Functional interaction between TRPV1 and mu-opioid receptors in the descending antinociceptive pathway activates glutamate transmission and induces analgesia.

abstract：:We compared the spatial sensitivity of neural responses in three areas of cat auditory cortex: primary auditory cortex (A1), the posterior auditory field (PAF), and the dorsal zone (DZ). Stimuli were 80-ms pure tones or broadband noise bursts varying in free-field azimuth (in the horizontal plane) or elevation (in the...

journal_title：Journal of neurophysiology

authors： Stecker GC,Harrington IA,Macpherson EA,Middlebrooks JC

更新日期：2005-08-01 00:00:00

abstract：:When the head is free to move, electrical stimulation in the frontal eye field (FEF) evokes eye and head movements. However, it is unclear whether FEF stimulation-evoked head movements contribute to shifting the line of sight, like visually guided coordinated eye-head gaze shifts. Here we investigated this issue by sy...

journal_title：Journal of neurophysiology

authors： Chen LL

更新日期：2006-06-01 00:00:00

abstract：:Dopamine (DA) neurons and GABA neurons of the substantia nigra (SN) promote distinct functions in the control of movement and have different firing properties and action potential (AP) waveforms. APs recorded from DA and GABA neurons differed in amplitude, maximal rate of rise, and duration. In addition, the threshold...

journal_title：Journal of neurophysiology

authors： Seutin V,Engel D

更新日期：2010-06-01 00:00:00

abstract：:Previous research using a loud acoustic stimulus (LAS) to investigate motor preparation in reaction time (RT) tasks indicates that responses can be triggered well in advance of the presentation of an imperative stimulus (IS). This is intriguing given that high levels of response preparation cannot be maintained for lo...

journal_title：Journal of neurophysiology

authors： Marinovic W,de Rugy A,Lipp OV,Tresilian JR

更新日期：2013-02-01 00:00:00

abstract：:Central pattern generator (CPG) motor circuits underlying rhythmic behaviors provide feedback to the projection neuron inputs that drive these circuits. This feedback elicits projection neuron bursting linked to CPG rhythms. The brief periodic interruptions in projection neuron activity in turn influence CPG output, g...

journal_title：Journal of neurophysiology

authors： Blitz DM

更新日期：2017-08-01 00:00:00

abstract：:Avian auditory and vestibular hair cells regenerate after damage by ototoxic drugs, but until recently there was little evidence that regenerated vestibular hair cells function normally. In an earlier study we showed that the vestibuloocular reflex (VOR) is eliminated with aminoglycoside antibiotic treatment and recov...

journal_title：Journal of neurophysiology

authors： Goode CT,Carey JP,Fuchs AF,Rubel EW

更新日期：1999-03-01 00:00:00

abstract：:1. Depolarization-induced elevations of intracellular calcium concentration ([Ca2+]i) were examined in slice-cultured hippocampal pyramidal and nonpyramidal cells of the CA3 region by combined intracellular and multisite fura-2 recording techniques. 2. In pyramidal cells, spiking activity induced by depolarizing curre...

journal_title：Journal of neurophysiology

authors： Knöpfel T,Gähwiler BH

更新日期：1992-09-01 00:00:00

abstract：:The lability of the responses of mammalian central neurons to gamma-aminobutyric acid (GABA) was studied using neurons acutely dissociated from the CA1 region of the adult guinea pig hippocampus as a model system. GABA was applied to the neuronal somata by pressure ejection and the resulting current (IGABA) recorded u...

journal_title：Journal of neurophysiology

authors： Huguenard JR,Alger BE

更新日期：1986-07-01 00:00:00

abstract：:Hilar mossy cells represent a unique population of local circuit neurons in the hippocampus and dentate gyrus. Here we use electrophysiological techniques in acute preparations of hippocampal slices to demonstrate that depolarization of a single hilar mossy cell can produce robust inhibition of local GABAergic afferen...

journal_title：Journal of neurophysiology

authors： Hofmann ME,Nahir B,Frazier CJ

更新日期：2006-11-01 00:00:00

abstract：:1. B31 and B32 are pattern-initiator neurons in the buccal ganglia of Aplysia. Along with the B61/B62 neurons, B31/B32 are also motor neurons that innervate the 12 buccal muscle via the I2 nerve. This research was aimed at determining the physiological functions of the B31/B32 and B61/B62 neurons, and of the I2 muscle...

journal_title：Journal of neurophysiology

authors： Hurwitz I,Neustadter D,Morton DW,Chiel HJ,Susswein AJ

更新日期：1996-04-01 00:00:00

abstract：:Properties, developmental regulation, and cAMP modulation of the hyperpolarization-activated current (I(h)) were investigated by the whole cell patch-clamp technique in vestibular ganglion neurons of the rat at two postnatal stages (P7-10 and P25-28). In addition, by RT-PCR and immunohistochemistry the identity and di...

journal_title：Journal of neurophysiology

authors： Almanza A,Luis E,Mercado F,Vega R,Soto E

更新日期：2012-10-01 00:00:00

abstract：:1. Neurons (n = 142) were recorded with extracellular micropipettes in the parabrachial (PB) area, in the anesthetized rat, some of them being antidromically driven from the centralis nucleus of the amygdala (Ce). The spontaneous activity of these neurons was low, (10th percentile < median frequency < 90th percentile;...

journal_title：Journal of neurophysiology

authors： Bernard JF,Huang GF,Besson JM

更新日期：1994-05-01 00:00:00

abstract：:Neurons in the visual cortex respond selectively to stimulus orientation and spatial frequency. Changes in response amplitudes of these neurons could be the neurophysiological basis of orientation and spatial frequency discrimination. We have estimated the minimum differences in stimulus orientation and spatial freque...

journal_title：Journal of neurophysiology

authors： Bradley A,Skottun BC,Ohzawa I,Sclar G,Freeman RD

更新日期：1987-03-01 00:00:00

abstract：:Filamentous actin (F-actin) was measured in cultured rat cerebellum granule neurons with the use of fluorescently labeled phallotoxin as a site-specific probe for F-actin, and fluorescence microscopy. The averaged apparent intensity of soma-associated F-actin-derived fluorescence (F(app)) was measured from fixed cells...

journal_title：Journal of neurophysiology

authors： Shorte SL

更新日期：1997-08-01 00:00:00

abstract：:Neurons in the medial superior olive (MSO) are tuned to the interaural time difference (ITD) of sound arriving at the two ears. MSO neurons evoke a strongest response at their best delay (BD), at which the internal delay between bilateral inputs to MSO matches the external ITD. We performed extracellular recordings in...

journal_title：Journal of neurophysiology

authors： Day ML,Semple MN

更新日期：2011-10-01 00:00:00

abstract：:1. Cellular properties were studied before and after bath application of the dihydropyridine L-type calcium channel antagonist nimodipine in aging and young rabbit hippocampal CA1 pyramidal cells in vitro. Various concentrations of nimodipine, ranging from 10 nM to 10 microM, were tested to investigate age- and concen...

journal_title：Journal of neurophysiology

authors： Moyer JR Jr,Thompson LT,Black JP,Disterhoft JF

更新日期：1992-12-01 00:00:00

abstract：:Previous studies of visual processing in humans using event-related potentials (ERPs) have demonstrated that task-related modulations of an early component called the "N1" wave (140-200 ms) reflect the operation of a voluntary discrimination process. Specifically, this component is larger in tasks requiring target dis...

journal_title：Journal of neurophysiology

authors： Hopf JM,Vogel E,Woodman G,Heinze HJ,Luck SJ

更新日期：2002-10-01 00:00:00

abstract：:To study the possible role of the cerebellum in the vestibular-ocular reflex, extracellular responses of cerebellar nuclear neurons were recorded in awake monkeys during natural vestibular stimulation; 115 neurons in the fastigial nucleus responded to horizontal sinusoidal accelerations applied to the head by means of...

journal_title：Journal of neurophysiology

authors： Gardner EP,Fuchs AF

更新日期：1975-05-01 00:00:00

abstract：:1. The hyperpolarization that follows tetanic stimulation was recorded intra-axonally from the internodal region of intramuscular myelinated motor axons. 2. The peak amplitude of the posttetanic hyperpolarization (PTH) that followed stimulation at 20-100 Hz for < or = 35 s increased with increasing train duration, rea...

journal_title：Journal of neurophysiology

authors： Morita K,David G,Barrett JN,Barrett EF

更新日期：1993-11-01 00:00:00

abstract：:Orexin-producing neurons are clearly essential for the regulation of wakefulness and sleep because loss of these cells produces narcolepsy. However, little is understood about how these neurons dynamically interact with other wake- and sleep-regulatory nuclei to control behavioral states. Using survival analysis of wa...

journal_title：Journal of neurophysiology

authors： Diniz Behn CG,Kopell N,Brown EN,Mochizuki T,Scammell TE

更新日期：2008-06-01 00:00:00

abstract：:Working memory (WM) for sensory-based information about individual objects and their locations appears to involve interactions between lateral prefrontal and sensory cortexes. The mechanisms and representations for maintenance of more abstract, nonsensory information in WM are unknown, particularly whether such active...

journal_title：Journal of neurophysiology

authors： Ikkai A,Blacker KJ,Lakshmanan BM,Ewen JB,Courtney SM

更新日期：2014-10-15 00:00:00

abstract：:The presence of a calcium-activated nonspecific cationic (CAN) current in turtle motoneurons and its involvement in plateau potentials, bistability, and wind-up was investigated by intracellular recordings in a spinal cord slice preparation. In the presence of tetraethylammonium (TEA) and tetrodotoxin (TTX), calcium a...

journal_title：Journal of neurophysiology

authors： Perrier JF,Hounsgaard J

更新日期：1999-08-01 00:00:00

abstract：:Studying adaptation to Coriolis perturbations of arm movements has advanced our understanding of motor control and learning. We have now applied this paradigm to two-dimensional postural sway. We measured how subjects (n = 8) standing at the center of a fully enclosed rotating room who made voluntary anterior-posterio...

journal_title：Journal of neurophysiology

authors： Bakshi A,DiZio P,Lackner JR

更新日期：2019-06-01 00:00:00

abstract：:Speech stimuli give rise to neural activity in the listener that can be observed as waveforms using magnetoencephalography. Although waveforms vary greatly from trial to trial due to activity unrelated to the stimulus, it has been demonstrated that spoken sentences can be discriminated based on theta-band (3-7 Hz) pha...

journal_title：Journal of neurophysiology

authors： Howard MF,Poeppel D

更新日期：2010-11-01 00:00:00

abstract：:The underlying neurophysiology of postural control of the lower back in humans is poorly understood. We have characterized motor unit (MU) discharge activity in the deep lumbar multifidus (LM) muscle in nine healthy subjects (20-40 yr, 3 females). Bilateral fine wire electrodes were implanted at L4 spinal level using ...

journal_title：Journal of neurophysiology

authors： Lothe LR,Raven TJ,Eken T

更新日期：2015-08-01 00:00:00

abstract：:1. The antidromic compound action potential (ACAP) of the auditory nerve was evoked by shocks to the auditory nerve root and recorded at the round window of the cochlea in anesthetized guinea pigs. The goal of this study was to determine the characteristics of the ACAP and compare these characteristics with those of t...

journal_title：Journal of neurophysiology

authors： Brown MC

更新日期：1994-05-01 00:00:00

abstract：:In recent years a small number of studies have applied functional imaging techniques to investigate visual responses in the human superior colliculus (SC), but few have investigated its oculomotor functions. Here, in two experiments, we examined activity associated with endogenous saccade preparation. We used 3-T fMRI...

journal_title：Journal of neurophysiology

authors： Furlan M,Smith AT,Walker R

更新日期：2015-08-01 00:00:00

abstract：:Motor imagery (MI) is a promising rehabilitation technique that has received significant interest for use in persons with multiple sclerosis (MS). Through alterations in neural networks, MI has the potential to improve measures of walking speed, walking distance, and fatigue in people with MS. Further research is requ...

journal_title：Journal of neurophysiology

authors： Hanson M,Concialdi M

更新日期：2019-02-01 00:00:00

abstract：:The suppressive action of a moving textured background on responses to moving bars was investigated in 118 striate neurons, 19 dorsal lateral geniculate neurons, and 5 perigeniculate neurons in paralyzed and anesthetized cats. In standard conditions the background was a two-dimensional (2D) noise pattern, the bar move...

journal_title：Journal of neurophysiology

authors： Gulyás B,Orban GA,Duysens J,Maes H

更新日期：1987-06-01 00:00:00

abstract：:The widespread noradrenergic innervation in the brain promotes arousal and learning by molecular mechanisms that remain largely undefined. Recent work shows that the β(2)-adrenergic receptor (β(2)AR) is linked to the AMPA-type glutamate receptor subunit GluA1 via stargazin and PSD-95 (Joiner ML, Lise MF, Yuen EY, Kam ...

journal_title：Journal of neurophysiology

authors： Qian H,Matt L,Zhang M,Nguyen M,Patriarchi T,Koval OM,Anderson ME,He K,Lee HK,Hell JW

更新日期：2012-05-01 00:00:00