Determination of electron energy, spectral width, and beam divergence at the exit window for clinical megavoltage x-ray beams.

Abstract:

:Monte Carlo simulations of x-ray beams typically take parameters of the electron beam in the accelerating waveguide to be free parameters. In this paper, a methodology is proposed and implemented to determine the energy, spectral width, and beam divergence of the electron source. All treatment head components were removed from the beam path, leaving only the exit window. With the x-ray target and flattener out of the beam, uncertainties in physical characteristics and relative position of the target and flattening filter, and in spot size, did not contribute to uncertainty in the energy. Beam current was lowered to reduce recombination effects. The measured dose distributions were compared with Monte Carlo simulation of the electron beam through the treatment head to extract the electron source characteristics. For the nominal 6 and 18 MV x-ray beams, the energies were 6.51 +/- 0.15 and 13.9 +/- 0.2 MeV, respectively, with the uncertainties resulting from uncertainties in the detector position in the measurement and in the stopping power in the simulations. Gaussian spectral distributions were used, with full widths at half maximum ranging from 20 +/- 4% at 6 MV to 13 +/- 4% at 18 MV required to match the fall-off portion of the percent-depth ionization curve. Profiles at the depth of maximum dose from simulations that used the manufacturer-specified exit window geometry and no beam divergence were 2-3 cm narrower than measured profiles. Two simulation configurations yielding the measured profile width were the manufacturer-specified exit window thickness with electron source divergences of 3.3 degrees at 6 MV and 1.8 degrees at 18 MV and an exit window 40% thicker than the manufacturer's specification with no beam divergence. With the x-ray target in place (and no flattener), comparison of measured to simulated profiles sets upper limits on the electron source divergences of 0.2 degrees at 6 MV and 0.1 degrees at 18 MV. A method of determining source characteristics without mechanical modification of the treatment head, and therefore feasible in clinics, is presented. The energies and spectral widths determined using this method agree with those determined with only the exit window in the beam path.

journal_name

Med Phys

journal_title

Medical physics

authors

Sawkey DL,Faddegon BA

doi

10.1118/1.3070547

subject

Has Abstract

pub_date

2009-03-01 00:00:00

pages

698-707

issue

3

eissn

0094-2405

issn

2473-4209

journal_volume

36

pub_type

杂志文章
  • CUDA-based acceleration and BPN-assisted automation of bilateral filtering for brain MR image restoration.

    abstract:PURPOSE:Bilateral filters have been substantially exploited in numerous magnetic resonance (MR) image restoration applications for decades. Due to the deficiency of theoretical basis on the filter parameter setting, empirical manipulation with fixed values and noise variance-related adjustments has generally been emplo...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12157

    authors: Chang HH,Chang YN

    更新日期:2017-04-01 00:00:00

  • An adaptive probabilistic atlas for anomalous brain segmentation in MR images.

    abstract:PURPOSE:Automated segmentation of brain structures (objects) in MR three-dimensional (3D) images for quantitative analysis has been a challenge and probabilistic atlases (PAs) are among the most well-succeeded approaches. However, the existing models do not adapt to possible object anomalies due to the presence of a di...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.13771

    authors: Martins SB,Bragantini J,Falcão AX,Yasuda CL

    更新日期:2019-11-01 00:00:00

  • Ultrafast treatment plan optimization for volumetric modulated arc therapy (VMAT).

    abstract:PURPOSE:To develop a novel aperture-based algorithm for volumetric modulated are therapy (VMAT) treatment plan optimization with high quality and high efficiency. METHODS:The VMAT optimization problem is formulated as a large-scale convex programming problem solved by a column generation approach. The authors consider...

    journal_title:Medical physics

    pub_type: 信件

    doi:10.1118/1.3491675

    authors: Men C,Romeijn HE,Jia X,Jiang SB

    更新日期:2010-11-01 00:00:00

  • Off-axis beam quality change in linear accelerator x-ray beams.

    abstract::The effective energy of the x-ray beam from linear accelerators changes as a function of the position in the beam due to nonuniform filtration by the flattening filter. In this work, the transmittance through a water column was measured in good geometry and the beam quality characterized in units of HVL in water. Meas...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.594677

    authors: Hanson WF,Berkley LW,Peterson M

    更新日期:1980-03-01 00:00:00

  • An optimization algorithm for 3D real-time lung tumor tracking during arc therapy using kV projection images.

    abstract:PURPOSE:To develop a real-time markerless 3D tumor tracking using kilovoltage (kV) cone-beam CT (CBCT) projection images during volumetric modulated arc therapy (VMAT) treatment of lung tumors. METHODS:The authors have developed a method to identify the position of lung tumors during VMAT treatment, where the current ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4821545

    authors: Zhuang L,Liang J,Yan D,Zhang T,Marina O,Ionascu D

    更新日期:2013-10-01 00:00:00

  • Correcting TG 119 confidence limits.

    abstract:PURPOSE:Task Group 119 (TG-119) has been adopted for evaluating the adequacy of intensity-modulated radiation therapy (IMRT) commissioning and for establishing patient-specific IMRT quality assurance (QA) passing criteria in clinical practice. TG-119 establishes 95% confidence limits (CLs), which help clinics identify ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12759

    authors: Kearney V,Solberg T,Jensen S,Cheung J,Chuang C,Valdes G

    更新日期:2018-03-01 00:00:00

  • A clinically feasible method for the detection of potential collision in proton therapy.

    abstract:PURPOSE:Potential collision between the patient∕couch and the gantry could delay the start of the treatment and reduce clinical efficiency. The ability to accurately detect possible collisions during the treatment planning phase is desired. Such collision detection should account for the specific proton gantry design, ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4760988

    authors: Zou W,Lin H,Plastaras JP,Wang H,Bui V,Vapiwala N,McDonough J,Tochner Z,Both S

    更新日期:2012-11-01 00:00:00

  • Super-resolution reconstruction for 4D computed tomography of the lung via the projections onto convex sets approach.

    abstract:PURPOSE:The use of 4D computed tomography (4D-CT) of the lung is important in lung cancer radiotherapy for tumor localization and treatment planning. Sometimes, dense sampling is not acquired along the superior-inferior direction. This disadvantage results in an interslice thickness that is much greater than in-plane v...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4899185

    authors: Zhang Y,Wu X,Yang W,Feng Q,Chen W

    更新日期:2014-11-01 00:00:00

  • Effect of respiratory gating on reducing lung motion artifacts in PET imaging of lung cancer.

    abstract::Positron emission tomography (PET) has shown an increase in both sensitivity and specificity over computed tomography (CT) in lung cancer. However, motion artifacts in the 18F fluorodioxydoglucose (FDG) PET images caused by respiration persists to be an important factor in degrading PET image quality and quantificatio...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1448824

    authors: Nehmeh SA,Erdi YE,Ling CC,Rosenzweig KE,Squire OD,Braban LE,Ford E,Sidhu K,Mageras GS,Larson SM,Humm JL

    更新日期:2002-03-01 00:00:00

  • Noise power spectra of images from digital mammography detectors.

    abstract::Noise characterization through estimation of the noise power spectrum (NPS) is a central component of the evaluation of digital x-ray systems. We begin with a brief review of the fundamentals of NPS theory and measurement, derive explicit expressions for calculation of the one- and two-dimensional (1D and 2D) NPS, and...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.598623

    authors: Williams MB,Mangiafico PA,Simoni PU

    更新日期:1999-07-01 00:00:00

  • Registration of central paths and colonic polyps between supine and prone scans in computed tomography colonography: pilot study.

    abstract::Computed tomography colonography (CTC) is a minimally invasive method that allows the evaluation of the colon wall from CT sections of the abdomen/pelvis. The primary goal of CTC is to detect colonic polyps, precursors to colorectal cancer. Because imperfect cleansing and distension can cause portions of the colon wal...

    journal_title:Medical physics

    pub_type: 临床试验,杂志文章

    doi:10.1118/1.1796171

    authors: Li P,Napel S,Acar B,Paik DS,Jeffrey RB Jr,Beaulieu CF

    更新日期:2004-10-01 00:00:00

  • SU-F-BRCD-06: Multiple Anatomy Optimization of Accumulated Dose.

    abstract:PURPOSE:Multiple anatomy optimization (MAO) utilizing deformable dose accumulation on entire 4DCT data sets is implemented to overcome ambiguity between optimal dose defined on a single anatomy and optimal accumulated dose resulting from dose delivery to moving and deforming anatomy. METHODS:Six lung cancer patients a...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735744

    authors: Watkins WT,Moore JA,Sharma M,Dial C,Xu H,Hugo GD,Gordon JJ,Siebers JV

    更新日期:2012-06-01 00:00:00

  • A Monte Carlo estimation of effective dose in chest tomosynthesis.

    abstract:PURPOSE:The recent introduction of digital tomosynthesis imaging into routine clinical use has enabled the acquisition of volumetric patient data within a standard radiographic examination. Tomosynthesis requires the acquisition of multiple projection views, requiring additional dose compared to a standard projection e...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3250907

    authors: Sabol JM

    更新日期:2009-12-01 00:00:00

  • Verification of absorbed dose determined with plane-parallel chambers in clinical electron beams following AAPM Task Group 39 protocol using ferrous sulphate dosimetry.

    abstract::The absorbed dose values determined with the Exradin and PTW-Markus plane-parallel chambers were compared to the values obtained with the ferrous sulphate dosimetry for a number of the Philips SL25 and the Therac 20 electron beams. For the plane-parallel chambers, the cavity-gas calibration factor Ngaspp, was derived ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.597800

    authors: Xu Z,Li H,Almond PR,Guan TY

    更新日期:1996-03-01 00:00:00

  • Optimized low-kV spectrum of dual-energy CT equipped with high-kV tin filtration for electron density measurements.

    abstract:PURPOSE:This paper describes the low-kV spectral optimization of dual-energy CT (DECT) equipped with high-kV tin filtration for the quantitative acquisition of electron density information, which is essential for treatment planning in radiotherapy. In addition, an analytical DECT image simulation was preliminarily perf...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3584200

    authors: Saito M

    更新日期:2011-06-01 00:00:00

  • Automatic three-dimensional correlation of CT-CT, CT-MRI, and CT-SPECT using chamfer matching.

    abstract::Image correlation is often required to utilize the complementary information in CT, MRI, and SPECT. A practical method for automatic image correlation in three-dimensions (3D) based on chamfer matching is described. The method starts with automatic extraction of contour points in one modality and automatic segmentatio...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.597344

    authors: van Herk M,Kooy HM

    更新日期:1994-07-01 00:00:00

  • Radiofrequency transmit calibration: A multi-center evaluation of vendor-provided radiofrequency transmit mapping methods.

    abstract:PURPOSE:To determine the accuracy and test-retest repeatability of fast radiofrequency (RF) transmit measurement approaches used in Dynamic Contrast Enhanced Magnetic Resonance Imaging (DCE-MRI). Spatial variation in the transmitted RF field introduces bias and increased variance in quantitative DCE-MRI metrics includi...

    journal_title:Medical physics

    pub_type: 杂志文章,多中心研究

    doi:10.1002/mp.13518

    authors: Bliesener Y,Zhong X,Guo Y,Boss M,Bosca R,Laue H,Chung C,Sung K,Nayak KS

    更新日期:2019-06-01 00:00:00

  • TU-E-BRB-01: Similar-Case-Based Optimization of Beam Arrangements in Stereotactic Body Radiation Therapy.

    abstract:PURPOSE:The quality of a treatment plan for stereotactic body radiotherapy (SBRT) depends on an experience of each treatment planner. Therefore, the treatment plans are subjectively determined by comparison of several treatment plans developed by time consuming iterative manners, while considering the benefit to a tumo...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735950

    authors: Magome T,Arimura H,Shioyama Y,Mizoguchi A,Tokunaga C,Nakamura K,Honda H,Ohki M,Toyofuku F,Hirata H

    更新日期:2012-06-01 00:00:00

  • An improved neutron collimator for brain tumor irradiations in clinical boron neutron capture therapy.

    abstract::To improve beam penetration into a head allowing the treatment of deeper seated tumors, two neutron collimators were built sequentially and tested for use in the clinical boron neutron capture therapy (BNCT) program at the epithermal neutron irradiation facility of the Brookhaven Medical Research Reactor. The collimat...

    journal_title:Medical physics

    pub_type: 临床试验,杂志文章

    doi:10.1118/1.597772

    authors: Liu HB,Greenberg DD,Capala J,Wheeler FJ

    更新日期:1996-12-01 00:00:00

  • Performance tests of two portable mini gamma cameras for medical applications.

    abstract::We have developed two prototypes of portable gamma cameras for medical applications based on a previous prototype designed and tested by our group. These cameras use a CsI(Na) continuous scintillation crystal coupled to the new flat-panel-type multianode position-sensitive photomultiplier tube, H8500 from Hamamatsu Ph...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2358199

    authors: Sánchez F,Fernández MM,Giménez M,Benlloch JM,Rodríguez-Alvarez MJ,García de Quirós F,Lerche Ch,Pavón N,Palazón JA,Martínez J,Sebastiá A

    更新日期:2006-11-01 00:00:00

  • SU-E-T-300: Monte Carlo Simulation of Single-Plane Magnetically Focused Narrow Proton Beams.

    abstract::Purpose To investigate narrow, elongated magnetically focused proton beams and compare their properties with passively collimated beams using Monte Carlo simulation. METHODS:We performed Geant4 Monte Carlo simulations involving a single quadrapole focusing magnet, thereby creating a flattened beam with an elongated e...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735386

    authors: McAuley G,Barnes S,Wroe A,Slater J

    更新日期:2012-06-01 00:00:00

  • SU-E-T-476: GPU-Based Monte Carlo Radiotherapy Dose Calculation Using Phase- Space Sources.

    abstract:PURPOSE:To design an efficient method for utilizing phase-space source models in the GPU-based Monte Carlo (MC) dose calculation engine gDPM. METHODS:In GPU-based MC algorithms, particles are transported in parallel on different threads. Particles of different types and energies can require significantly different exe...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735565

    authors: Townson R,Jia X,Zavgorodni S,Jiang S

    更新日期:2012-06-01 00:00:00

  • Two-dimensional antiscatter grid: A novel scatter rejection device for Cone-beam computed tomography.

    abstract:PURPOSE:Scattered radiation remains to be a major cause of image quality degradation in Flat Panel Detector (FPD)-based Cone-beam computed tomography (CBCT). We have been investigating a novel two-dimensional antiscatter grid (2D-ASG) concept to reduce scatter intensity, and hence improve CBCT image quality. We present...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12724

    authors: Alexeev T,Kavanagh B,Miften M,Altunbas C

    更新日期:2018-02-01 00:00:00

  • Gamma dose measurement in a d(80) + Be neutron beam.

    abstract::The gamma-ray dose component of a d(80) + Be neutron beam was measured with a 6Li-shielded Geiger-Mueller counter in a tissue-equivalent liquid phantom. The proportion of gamma-ray dose to total dose increased from 0.07 near the surface to 0.09 at 25 cm depth. Due to thermal neutron sensitivity, the G-M count rate inc...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.594571

    authors: Harrison GH,Cox CR

    更新日期:1979-05-01 00:00:00

  • Nonlocal atlas-guided multi-channel forest learning for human brain labeling.

    abstract:PURPOSE:It is important for many quantitative brain studies to label meaningful anatomical regions in MR brain images. However, due to high complexity of brain structures and ambiguous boundaries between different anatomical regions, the anatomical labeling of MR brain images is still quite a challenging task. In many ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4940399

    authors: Ma G,Gao Y,Wu G,Wu L,Shen D

    更新日期:2016-02-01 00:00:00

  • Calculation of the radiological depth.

    abstract::The concept of the radiological depth is central to all algorithms which calculate radiation dose in a heterogeneous medium. For a discrete heterogeneous medium, consisting of regions of inhomogeneity, the radiological depth is usually presented as the sum over segments of the product of the segment length and the inh...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.595739

    authors: Siddon RL

    更新日期:1985-01-01 00:00:00

  • Physical characteristics of scattered radiation in diagnostic radiology: Monte Carlo simulation studies.

    abstract::We applied Monte Carlo methods for the simulation of x-ray scattering in water phantoms. The phantom thickness was varied from 5 to 20 cm, and the monoenergetic incident x rays were varied from 15 to 100 keV. Eight screen pairs and a total absorption system were used as x-ray receptors. We determined the angular, spec...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.595771

    authors: Chan HP,Doi K

    更新日期:1985-03-01 00:00:00

  • Convolutional neural network-based pelvic floor structure segmentation using magnetic resonance imaging in pelvic organ prolapse.

    abstract:PURPOSE:Automated segmentation could improve the efficiency of modeling-based pelvic organ prolapse (POP) evaluations. However, segmentation performance is limited by the blurry soft tissue boundaries. In this study, we aimed to present a hybrid solution for uterus, rectum, bladder, and levator ani muscle segmentation ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.14377

    authors: Feng F,Ashton-Miller JA,DeLancey JOL,Luo J

    更新日期:2020-09-01 00:00:00

  • In vivo functional chronic imaging of a small animal model using optical-resolution photoacoustic microscopy.

    abstract::Optical-resolution photoacoustic microscopy (OR-PAM) has been validated as a valuable tool for label-free volumetric microvascular imaging. More importantly, the advantages of noninvasiveness and measurement consistency suggest the use of OR-PAM for chronic imaging of intact microcirculation. Here, such chronic imagin...

    journal_title:Medical physics

    pub_type: 信件

    doi:10.1118/1.3137572

    authors: Hu S,Maslov K,Wang LV

    更新日期:2009-06-01 00:00:00

  • Evaluation of a direct motion estimation/correction method in respiratory-gated PET/MRI with motion-adjusted attenuation.

    abstract:PURPOSE:Respiratory motion compensation in PET/CT and PET/MRI is essential as motion is a source of image degradation (motion blur, attenuation artifacts). In previous work, we developed a direct method for joint image reconstruction/motion estimation (JRM) for attenuation-corrected (AC) respiratory-gated PET, which us...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12253

    authors: Bousse A,Manber R,Holman BF,Atkinson D,Arridge S,Ourselin S,Hutton BF,Thielemans K

    更新日期:2017-06-01 00:00:00