Should fertile people have access to in vitro fertilisation?

abstract：OBJECTIVE:To examine the relation between energy intake in childhood and adult mortality from cancer. STUDY DESIGN:Cohort study. SETTING:16 rural and urban centres in England and Scotland. SUBJECTS:3834 people who took part in Lord Boyd Orr's Carnegie survey of family diet and health in prewar Britain between 1937 a...

journal_title：BMJ (Clinical research ed.)

authors： Frankel S,Gunnell DJ,Peters TJ,Maynard M,Davey Smith G

更新日期：1998-02-14 00:00:00

abstract：:Lifetime fertility, abortion rates, and the proportion of pregnancies resulting in induced abortion were investigated in 105 district health authorities in England. In 1995, a total of 147,851 abortions occurred among women living in England, compared with 613,257 live births; a ratio of 1:4. This was equivalent to ...

journal_title：BMJ (Clinical research ed.)

authors： Raleigh VS

更新日期：1998-06-06 00:00:00

abstract：OBJECTIVE:To determine whether cognitive therapy is effective in preventing the worsening of emerging psychotic symptoms experienced by help seeking young people deemed to be at risk for serious conditions such as schizophrenia. DESIGN:Multisite single blind randomised controlled trial. SETTING:Diverse services at fi...

journal_title：BMJ (Clinical research ed.)

authors： Morrison AP,French P,Stewart SL,Birchwood M,Fowler D,Gumley AI,Jones PB,Bentall RP,Lewis SW,Murray GK,Patterson P,Brunet K,Conroy J,Parker S,Reilly T,Byrne R,Davies LM,Dunn G

更新日期：2012-04-05 00:00:00

abstract：OBJECTIVE:To systematically evaluate the published evidence regarding the characteristics and effectiveness of disease management programmes. DESIGN:Meta-analysis. DATA SOURCES:Computerised databases for English language articles during 1987-2001. STUDY SELECTION:102 articles evaluating 118 disease management progra...

journal_title：BMJ (Clinical research ed.)

authors： Weingarten SR,Henning JM,Badamgarav E,Knight K,Hasselblad V,Gano A Jr,Ofman JJ

更新日期：2002-10-26 00:00:00

abstract：OBJECTIVES:To assess the feasibility and effectiveness of a general practice based, proactive system of asthma care in children. DESIGN:Randomised controlled trial with cluster sampling by general practice. SETTING:General practices in the northern region of the Australian Capital Territory. PARTICIPANTS:174 childre...

journal_title：BMJ (Clinical research ed.)

authors： Glasgow NJ,Ponsonby AL,Yates R,Beilby J,Dugdale P

更新日期：2003-09-20 00:00:00

abstract：OBJECTIVES:To compare mix of patients, scope of practice, and duration of visit in primary care physicians in Australia, New Zealand, and the United States. DESIGN:Comparison of three comparable cross sectional surveys performed in 2001-2. Physicians completed a questionnaire on patients' demographics, diagnoses, and ...

journal_title：BMJ (Clinical research ed.)

authors： Bindman AB,Forrest CB,Britt H,Crampton P,Majeed A

更新日期：2007-06-16 00:00:00

abstract：OBJECTIVE:To test the hypothesis of an association between neonatal intramuscular vitamin K and childhood leukaemia and other cancers. DESIGN:Population based case-control study with data abstracted from hospital records. SETTING:Scotland. SUBJECTS:Children aged 0-14 years resident in Scotland from 1991-4 and diagno...

journal_title：BMJ (Clinical research ed.)

authors： McKinney PA,Juszczak E,Findlay E,Smith K

更新日期：1998-01-17 00:00:00

abstract：OBJECTIVE:To independently evaluate the impact of the second phase of the Health Foundation's Safer Patients Initiative (SPI2) on a range of patient safety measures. Design A controlled before and after design. Five substudies: survey of staff attitudes; review of case notes from high risk (respiratory) patients in med...

journal_title：BMJ (Clinical research ed.)

authors： Benning A,Dixon-Woods M,Nwulu U,Ghaleb M,Dawson J,Barber N,Franklin BD,Girling A,Hemming K,Carmalt M,Rudge G,Naicker T,Kotecha A,Derrington MC,Lilford R

更新日期：2011-02-03 00:00:00

abstract：OBJECTIVE:To describe the current methods used by English medical schools to identify prospective medical students for admission to the five year degree course. DESIGN:Review study including documentary analysis and interviews with admissions tutors. SETTING:All schools (n = 22) participating in the national expansio...

journal_title：BMJ (Clinical research ed.)

authors： Parry J,Mathers J,Stevens A,Parsons A,Lilford R,Spurgeon P,Thomas H

更新日期：2006-04-29 00:00:00

abstract：OBJECTIVE:To determine whether the author's 20.9 lb (9.5 kg) carbon frame bicycle reduced commuting time compared with his 29.75 lb (13.5 kg) steel frame bicycle. DESIGN:Randomised trial. SETTING:Sheffield and Chesterfield, United Kingdom, between mid-January 2010 and mid-July 2010. PARTICIPANTS:One consultant in an...

journal_title：BMJ (Clinical research ed.)

authors： Groves J

更新日期：2010-12-09 00:00:00

abstract：OBJECTIVE:To evaluate the effects of a multifaceted empowerment strategy on the actual use of single embryo transfer after in vitro fertilisation. DESIGN:Randomised controlled trial. SETTING:Five in vitro fertilisation clinics in the Netherlands. PARTICIPANTS:308 couples (women aged <40) on the waiting list for a fi...

journal_title：BMJ (Clinical research ed.)

authors： van Peperstraten A,Nelen W,Grol R,Zielhuis G,Adang E,Stalmeier P,Hermens R,Kremer J

更新日期：2010-09-30 00:00:00

abstract：OBJECTIVES:To examine how insurance companies assess proposals for life assurance from applicants with raised cholesterol concentrations and to determine the excess mortality rating applied. DESIGN:Survey of 49 companies underwriting term life assurance. SETTING:United Kingdom. SUBJECTS:Four fictional men aged 30 se...

journal_title：BMJ (Clinical research ed.)

authors： Neil HA,Mant D

更新日期：1991-04-13 00:00:00

abstract：OBJECTIVE:To study changes from 1969 to 1983 in the prognosis of patients with acute myocardial infarction treated in a coronary care unit. DESIGN:Mortality follow up of all patients with definite acute myocardial infarction. SETTING:The coronary care unit of the Royal Melbourne Hospital, a tertiary referral centre. ...

journal_title：BMJ (Clinical research ed.)

authors： Hopper JL,Pathik B,Hunt D,Chan WW

更新日期：1989-10-07 00:00:00

abstract：:This paper examines the impact of marital status on maternal mortality in the period before and the period after German reunification in the area covered by the former East Germany. Maternal mortality ratio prior to the reunification was stable and declined after reunification. This can be attributed to the adoption ...

journal_title：BMJ (Clinical research ed.)

authors： Razum O,Jahn A,Snow R

更新日期：1999-10-23 00:00:00

abstract：:In July 1992 Dr Keith Mumby, a clinical ecologist, appeared before the professional conduct committee of the General Medical Council on five charges to do with his practice of clinical ecology. He was found guilty of two of the charges--touting for publicity and failing to give a patient adequate medical attention--an...

journal_title：BMJ (Clinical research ed.)

authors： Kay AB

更新日期：1993-01-09 00:00:00

abstract：OBJECTIVE:To assess the association between macrolide antibiotics prescribing during pregnancy and major malformations, cerebral palsy, epilepsy, attention deficit hyperactivity disorder, and autism spectrum disorder in children. DESIGN:Population based cohort study. SETTING:The UK Clinical Practice Research Datalink...

journal_title：BMJ (Clinical research ed.)

authors： Fan H,Gilbert R,O'Callaghan F,Li L

更新日期：2020-02-19 00:00:00

abstract：OBJECTIVE:To discover if there is an association between respiratory tract infections and pericoronitis of erupting third molars in young adults. DESIGN:Data from male military conscripts' medical records were collected over five years and the incidence of respiratory tract infection before and after acute pericoronit...

journal_title：BMJ (Clinical research ed.)

authors： Meurman JH,Rajasuo A,Murtomaa H,Savolainen S

更新日期：1995-04-01 00:00:00

abstract：:Monocycline is the most widely prescribed systemic antibiotic for acne largely because it needs to be given only once or twice a day and seems not to induce resistance. Up to April 1994 11 cases of minocycline induced systemic lupus erythematosus and 16 cases of hepatitis had been reported to the Committee on Safety o...

journal_title：BMJ (Clinical research ed.)

authors： Gough A,Chapman S,Wagstaff K,Emery P,Elias E

更新日期：1996-01-20 00:00:00

abstract：OBJECTIVES:To determine whether the dose of vitamin A currently recommended by the World Health Organization or half this dose gives better protection against childhood morbidity and mortality. DESIGN:Randomised study. SETTING:A combined oral polio vaccine and vitamin A supplementation campaign in Guinea-Bissau, Afri...

journal_title：BMJ (Clinical research ed.)

authors： Benn CS,Martins C,Rodrigues A,Jensen H,Lisse IM,Aaby P

更新日期：2005-12-17 00:00:00

abstract：OBJECTIVE:To conduct a systematic review and meta-analysis of cohort studies of body mass index (BMI) and the risk of all cause mortality, and to clarify the shape and the nadir of the dose-response curve, and the influence on the results of confounding from smoking, weight loss associated with disease, and preclinical...

journal_title：BMJ (Clinical research ed.)

authors： Aune D,Sen A,Prasad M,Norat T,Janszky I,Tonstad S,Romundstad P,Vatten LJ

更新日期：2016-05-04 00:00:00

abstract：:In the existing WHO guidelines, complementary feeding at 4-6 months is advocated. However, many nutrition specialists believe that these guidelines lead to complementary foods being offered from the age of 3 months, or even earlier, subsequently suggesting that the WHO should change its recommendations to about 6 mon...

journal_title：BMJ (Clinical research ed.)

authors： Yamey G

更新日期：2000-09-09 00:00:00

abstract：OBJECTIVE:To evaluate the effectiveness and costs of a multifaceted flexible educational programme aimed at reducing antibiotic dispensing at the practice level in primary care. DESIGN:Randomised controlled trial with general practices as the unit of randomisation and analysis. Clinicians and researchers were blinded ...

journal_title：BMJ (Clinical research ed.)

authors： Butler CC,Simpson SA,Dunstan F,Rollnick S,Cohen D,Gillespie D,Evans MR,Alam MF,Bekkers MJ,Evans J,Moore L,Howe R,Hayes J,Hare M,Hood K

更新日期：2012-02-02 00:00:00

abstract：OBJECTIVES:To determine the clinical and radiological features of severe acute respiratory syndrome (SARS) and to evaluate the accuracy of the World Health Organization's guidelines on defining cases of SARS. DESIGN:Prospective observational study. SETTING:A newly set up SARS screening clinic in the emergency departm...

journal_title：BMJ (Clinical research ed.)

authors： Rainer TH,Cameron PA,Smit D,Ong KL,Hung AN,Nin DC,Ahuja AT,Si LC,Sung JJ

更新日期：2003-06-21 00:00:00

abstract：OBJECTIVE:To compare the clinical effectiveness of local corticosteroid injection, standard non-steroidal anti-inflammatory drugs, and simple analgesics for the early treatment of lateral epicondylitis in primary care. DESIGN:Multicentre pragmatic randomised controlled trial. SETTING:23 general practices in North Sta...

journal_title：BMJ (Clinical research ed.)

authors： Hay EM,Paterson SM,Lewis M,Hosie G,Croft P

更新日期：1999-10-09 00:00:00

abstract：OBJECTIVE:To assess the effectiveness of teaching general practitioners skills in brief cognitive behaviour therapy. DESIGN:Parallel group, cluster randomised, controlled trial of an educational package on cognitive behaviour therapy. SETTING:General practices in north London. PARTICIPANTS:84 general practitioner pr...

journal_title：BMJ (Clinical research ed.)

authors： King M,Davidson O,Taylor F,Haines A,Sharp D,Turner R

更新日期：2002-04-20 00:00:00

abstract：OBJECTIVE:To estimate the risk of breast cancer associated with diagnostic radiation in carriers of BRCA1/2 mutations. DESIGN:Retrospective cohort study (GENE-RAD-RISK). SETTING:Three nationwide studies (GENEPSO, EMBRACE, HEBON) in France, United Kingdom, and the Netherlands, PARTICIPANTS:1993 female carriers of BRC...

journal_title：BMJ (Clinical research ed.)

authors： Pijpe A,Andrieu N,Easton DF,Kesminiene A,Cardis E,Noguès C,Gauthier-Villars M,Lasset C,Fricker JP,Peock S,Frost D,Evans DG,Eeles RA,Paterson J,Manders P,van Asperen CJ,Ausems MG,Meijers-Heijboer H,Thierry-Chef I,Hau

更新日期：2012-09-06 00:00:00

abstract：OBJECTIVE:To evaluate the relative efficacy of programmed cell death 1 (PD-1) or programmed cell death ligand 1 (PD-L1) inhibitors versus conventional drugs in patients with cancer that were PD-L1 positive and PD-L1 negative. DESIGN:Meta-analysis of randomised controlled trials. DATA SOURCES:PubMed, Embase, Cochrane ...

journal_title：BMJ (Clinical research ed.)

authors： Shen X,Zhao B

更新日期：2018-09-10 00:00:00

abstract：OBJECTIVES:To identify the extent of HIV infection and injecting drug use among female streetworking prostitutes in Glasgow; to estimate the size of the female streetworking prostitute population in the city; and to estimate the number of HIV positive women working as prostitutes on the streets in Glasgow. DESIGN:Obse...

journal_title：BMJ (Clinical research ed.)

authors： McKeganey N,Barnard M,Leyland A,Coote I,Follet E

更新日期：1992-10-03 00:00:00

abstract：OBJECTIVE:To examine the absolute risks or benefits on cancer associated with oral contraception, using incident data. DESIGN:Inception cohort study. SETTING:Royal College of General Practitioners' oral contraception study. PARTICIPANTS:Directly standardised data from the Royal College of General Practitioners' oral...

journal_title：BMJ (Clinical research ed.)

authors： Hannaford PC,Selvaraj S,Elliott AM,Angus V,Iversen L,Lee AJ

更新日期：2007-09-29 00:00:00

abstract：OBJECTIVE:To investigate explanations for social inequalities in health with respect to health related social mobility and cumulative socioeconomic circumstances over the first three decades of life. DESIGN:Longitudinal follow up. SETTING:Great Britain. SUBJECTS:Data from the 1958 birth cohort study (all children bo...

journal_title：BMJ (Clinical research ed.)

authors： Power C,Matthews S,Manor O

更新日期：1996-08-24 00:00:00