Alternative allergy and the General Medical Council.

abstract：:Two patients with acute major, disabling cerebral infarction with presumed middle cerebral artery occlusion were treated with the clot specific thrombolytic agent tissue plasminogen activator roughly three and a half hours after the onset of symptoms. Both patients had a normal computed tomography (CT) scan before tre...

journal_title：BMJ (Clinical research ed.)

authors： Koudstaal PJ,Stibbe J,Vermeulen M

更新日期：1988-12-17 00:00:00

abstract：OBJECTIVE:To estimate trends between 1972-6 and 1996 in the prevalences of asthma and hay fever in adults. DESIGN:Two epidemiological surveys 20 years apart. Identical questions were asked about asthma, hay fever, and respiratory symptoms at each survey. SETTING:Renfrew and Paisley, two towns in the west of Scotland....

journal_title：BMJ (Clinical research ed.)

authors： Upton MN,McConnachie A,McSharry C,Hart CL,Smith GD,Gillis CR,Watt GC

更新日期：2000-07-08 00:00:00

abstract：:The instrument through which a commissioner purchases health services from a provider is, as in other walks of life, a contract, so considerable importance has been attached by the NHS Executive to the contracting mechanism. A contract should in theory influence the quality of the service provided, but they are in man...

journal_title：BMJ (Clinical research ed.)

authors： Hopkins A,Solomon JK

更新日期：1996-08-24 00:00:00

abstract：OBJECTIVE:To examine the relation between diameters of the retinal arterioles and 10 year incidence of hypertension. DESIGN:Population based prospective cohort study. SETTING:Beaver Dam eye study. PARTICIPANTS:2451 normotensive people aged 43 to 84 years. MAIN OUTCOME MEASURES:Diameters of retinal arterioles and ve...

journal_title：BMJ (Clinical research ed.)

authors： Wong TY,Shankar A,Klein R,Klein BE,Hubbard LD

更新日期：2004-07-10 00:00:00

abstract：:A committee of French bishops has contradicted the Vatican's condemnation of all methods of contraception by acknowledging that condom use may be necessary in order to prevent the spread of HIV and protect against AIDS. The Social Commission of the French Episcopate made this statement in a book entitled AIDS: Societ...

journal_title：BMJ (Clinical research ed.)

authors： Dorozynski A

更新日期：1996-02-24 00:00:00

abstract：:Molecular techniques have revolutionised our knowledge of cell and tissue function in both health and disease. We already have new and powerful treatments based on an understanding of communication between cells by messenger molecules called cytokines. Furthermore, there is great therapeutic promise in defining molecu...

journal_title：BMJ (Clinical research ed.)

authors： Savill J

更新日期：1997-01-18 00:00:00

abstract：OBJECTIVES:To compare patients' preference for transdermal fentanyl or sustained release oral morphine, their level of pain control, and their quality of life after treatment. DESIGN:Randomised, multicentre, international, open label, crossover trial. SETTING:35 centres in Belgium, Canada, Denmark, Finland, the Unite...

journal_title：BMJ (Clinical research ed.)

authors： Allan L,Hays H,Jensen NH,de Waroux BL,Bolt M,Donald R,Kalso E

更新日期：2001-05-12 00:00:00

abstract：:The recent growth in the numbers of published systematic reviews reflects growing recognition of their importance for improving knowledge about the effects of health care. In Britain the NHS R&D Programme has established two centres to prepare systematic reviews of existing information, and the Cochrane Collaboration-...

journal_title：BMJ (Clinical research ed.)

authors： Chalmers I,Haynes B

更新日期：1994-10-01 00:00:00

abstract：OBJECTIVE:To examine the association between intake of different types of alcoholic drinks and mortality. DESIGN:Prospective population study with baseline assessment of alcohol intake, smoking habit, income, education, and body mass index, and 10-12 years' follow up of mortality. SETTING:Copenhagen city heart study,...

journal_title：BMJ (Clinical research ed.)

authors： Grønbaek M,Deis A,Sørensen TI,Becker U,Schnohr P,Jensen G

更新日期：1995-05-06 00:00:00

abstract：OBJECTIVE:To evaluate systematically the review literature on type 2 diabetes to assess transmission of the findings of the United Kingdom prospective diabetes study (UKPDS), an important source of recent valid patient oriented evidence that matters (POEMs). DESIGN:Inception cohort analysis of the recent medical liter...

journal_title：BMJ (Clinical research ed.)

authors： Shaughnessy AF,Slawson DC

更新日期：2003-08-02 00:00:00

abstract：OBJECTIVE:To assess the accuracy of the AbC-19 Rapid Test lateral flow immunoassay for the detection of previous severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. DESIGN:Test accuracy study. SETTING:Laboratory based evaluation. PARTICIPANTS:2847 key workers (healthcare staff, fire and rescue of...

journal_title：BMJ (Clinical research ed.)

authors： Mulchandani R,Jones HE,Taylor-Phillips S,Shute J,Perry K,Jamarani S,Brooks T,Charlett A,Hickman M,Oliver I,Kaptoge S,Danesh J,Di Angelantonio E,Ades AE,Wyllie DH,EDSAB-HOME and COMPARE Investigators.

更新日期：2020-11-11 00:00:00

abstract：OBJECTIVE:To compare patient outcomes of restrictive versus liberal blood transfusion strategies in patients with cardiovascular disease not undergoing cardiac surgery. DESIGN:Systematic review and meta-analysis. DATA SOURCES:Randomised controlled trials involving a threshold for red blood cell transfusion in hospita...

journal_title：BMJ (Clinical research ed.)

authors： Docherty AB,O'Donnell R,Brunskill S,Trivella M,Doree C,Holst L,Parker M,Gregersen M,Pinheiro de Almeida J,Walsh TS,Stanworth SJ

更新日期：2016-03-29 00:00:00

abstract：PROBLEM:To reduce hospital inpatient mortality and thus increase public confidence in the quality of patient care in an urban acute hospital trust after adverse media coverage. DESIGN:Eight care bundles of treatments known to be effective in reducing in-hospital mortality were used in the intervention year; adjusted m...

journal_title：BMJ (Clinical research ed.)

authors： Robb E,Jarman B,Suntharalingam G,Higgens C,Tennant R,Elcock K

更新日期：2010-03-31 00:00:00

abstract：OBJECTIVE:To examine the protective efficacy of measles vaccination in infants in a low income country before 9 months of age. DESIGN:Randomised clinical trial. PARTICIPANTS:1333 infants aged 4.5 months: 441 in treatment group and 892 in control group. SETTING:Urban area in Guinea-Bissau. INTERVENTION:Measles vacci...

journal_title：BMJ (Clinical research ed.)

authors： Martins CL,Garly ML,Balé C,Rodrigues A,Ravn H,Whittle HC,Lisse IM,Aaby P

更新日期：2008-07-24 00:00:00

abstract：:The meaning of the GP contract has changed since the last major upheaval in the mid-1960s. The government has always dealt with general practitioners as independent contractors, but the way in which it treated them in 1990 was entirely different from the way in which they were treated in 1966. In 1966, the profession'...

journal_title：BMJ (Clinical research ed.)

authors： Lewis J

更新日期：1997-03-22 00:00:00

abstract：OBJECTIVE:To establish the extent of prescribing injectable and oral methadone to opiate addicts and the practice characteristics and dispensing arrangements attached to these prescriptions. DESIGN:National survey of 25% random sample of community (high street) pharmacies through postal questionnaire, with four mailin...

journal_title：BMJ (Clinical research ed.)

authors： Strang J,Sheridan J,Barber N

更新日期：1996-08-03 00:00:00

abstract：OBJECTIVE:To assess the cost-effectiveness of low dose statins for primary prevention of vascular disease, incorporating current prices, non-adherence (reduced clinical efficacy while maintaining healthcare costs), and the results of the recently published JUPITER trial. DESIGN:Cost-effectiveness analysis using a Mark...

journal_title：BMJ (Clinical research ed.)

authors： Greving JP,Visseren FL,de Wit GA,Algra A

更新日期：2011-03-30 00:00:00

abstract：OBJECTIVE:To assess whether a strategy of endovascular repair (if aortic morphology is suitable, open repair if not) versus open repair reduces early mortality for patients with suspected ruptured abdominal aortic aneurysm. DESIGN:Randomised controlled trial. SETTING:30 vascular centres (29 UK, 1 Canadian), 2009-13. ...

journal_title：BMJ (Clinical research ed.)

authors： IMPROVE Trial Investigators.,Powell JT,Sweeting MJ,Thompson MM,Ashleigh R,Bell R,Gomes M,Greenhalgh RM,Grieve R,Heatley F,Hinchliffe RJ,Thompson SG,Ulug P

更新日期：2014-01-13 00:00:00

abstract：:In Oregon, Planned Parenthood and a group of physicians who perform abortions have filed a civil suit against several anti-abortion groups individuals. The suit seeks $200 million in damages and an injunction to bar the defendants from posting information on the Internet that threatens the lives and well-being of the...

journal_title：BMJ (Clinical research ed.)

authors： Charatan F

更新日期：1999-01-23 00:00:00

abstract：OBJECTIVE:To confirm the findings of pilot studies that interferon alfa is an effective treatment of Europid men with chronic hepatitis B virus infection. DESIGN:Randomised controlled trial of three months treatment with interferon alfa followed by 12 months of observation. SETTING:Outpatient clinic of a tertiary ref...

journal_title：BMJ (Clinical research ed.)

authors： Brook MG,Chan G,Yap I,Karayiannis P,Lever AM,Jacyna M,Main J,Thomas HC

更新日期：1989-09-09 00:00:00

abstract：OBJECTIVE:To determine the effectiveness of oral rehydration in children with moderate dehydration caused by gastroenteritis, and to compare the complications of oral and intravenous treatment. DESIGN:Randomised controlled trial. SETTING:Emergency department and infectious diseases ward in a large urban teaching hosp...

journal_title：BMJ (Clinical research ed.)

authors： Mackenzie A,Barnes G

更新日期：1991-08-17 00:00:00

abstract：OBJECTIVE:To evaluate the effect on general practitioners' prescribing of feedback on their levels of prescribing. DESIGN:Randomised controlled trial. SETTING:General practice in rural Australia. PARTICIPANTS:2440 full time recognised general practitioners practising in non-urban areas. INTERVENTION:Two sets of gra...

journal_title：BMJ (Clinical research ed.)

authors： O'Connell DL,Henry D,Tomlins R

更新日期：1999-02-20 00:00:00

abstract：OBJECTIVES:To study the effects of metformin on the incidence of vitamin B-12 deficiency (<150 pmol/l), low concentrations of vitamin B-12 (150-220 pmol/l), and folate and homocysteine concentrations in patients with type 2 diabetes receiving treatment with insulin. DESIGN:Multicentre randomised placebo controlled tri...

journal_title：BMJ (Clinical research ed.)

authors： de Jager J,Kooy A,Lehert P,Wulffelé MG,van der Kolk J,Bets D,Verburg J,Donker AJ,Stehouwer CD

更新日期：2010-05-20 00:00:00

abstract：OBJECTIVES:To report on the country of training and ethnicity of consultants in different specialties in the NHS, on trends in intake to UK medical schools by ethnicity, and on the specialty choices made by UK medical graduates in different ethnic groups. DESIGN:Analysis of official databases of consultants and of stu...

journal_title：BMJ (Clinical research ed.)

authors： Goldacre MJ,Davidson JM,Lambert TW

更新日期：2004-09-11 00:00:00

abstract：OBJECTIVE:To evaluate the effectiveness and costs of a multifaceted flexible educational programme aimed at reducing antibiotic dispensing at the practice level in primary care. DESIGN:Randomised controlled trial with general practices as the unit of randomisation and analysis. Clinicians and researchers were blinded ...

journal_title：BMJ (Clinical research ed.)

authors： Butler CC,Simpson SA,Dunstan F,Rollnick S,Cohen D,Gillespie D,Evans MR,Alam MF,Bekkers MJ,Evans J,Moore L,Howe R,Hayes J,Hare M,Hood K

更新日期：2012-02-02 00:00:00

abstract：OBJECTIVES:To examine the prospective associations between consumption of sugar sweetened beverages, artificially sweetened beverages, and fruit juice with type 2 diabetes before and after adjustment for adiposity, and to estimate the population attributable fraction for type 2 diabetes from consumption of sugar sweete...

journal_title：BMJ (Clinical research ed.)

authors： Imamura F,O'Connor L,Ye Z,Mursu J,Hayashino Y,Bhupathiraju SN,Forouhi NG

更新日期：2015-07-21 00:00:00

abstract：:Objective To estimate the cumulative radiation exposure and lifetime attributable risk of cancer incidence associated with lung cancer screening using annual low dose computed tomography (CT).Design Secondary analysis of data from a lung cancer screening trial and risk-benefit analysis.Setting 10 year, non-randomised,...

journal_title：BMJ (Clinical research ed.)

authors： Rampinelli C,De Marco P,Origgi D,Maisonneuve P,Casiraghi M,Veronesi G,Spaggiari L,Bellomi M

更新日期：2017-02-08 00:00:00

abstract：OBJECTIVE:To cost the relation between socioeconomic status and various measures of primary care workload and assess the adequacy of current "deprivation" payments in relation to actual costings for patients living in qualifying areas. DESIGN:Retrospective data on primary care were collected over a 4.5 year period fro...

journal_title：BMJ (Clinical research ed.)

authors： Worrall A,Rea JN,Ben-Shlomo Y

更新日期：1997-01-04 00:00:00

abstract：OBJECTIVES: To estimate differences in annual income of physicians in the United States by race and sex adjusted for characteristics of physicians and practices. DESIGN: Cross sectional survey study. SETTING: Nationally representative samples of US physicians. PARTICIPANTS: The 2000-13 American Community Survey (ACS...

journal_title：BMJ (Clinical research ed.)

authors： Ly DP,Seabury SA,Jena AB

更新日期：2016-06-07 00:00:00

abstract：OBJECTIVE:To assess the association between genotype at the insertion or deletion polymorphism of the angiotensin converting enzyme gene and risk of coronary restenosis after percutaneous coronary intervention. DESIGN:Meta-analysis of studies before July 2001 that reported on these genotypes and risk of coronary reste...

journal_title：BMJ (Clinical research ed.)

authors： Bonnici F,Keavney B,Collins R,Danesh J

更新日期：2002-09-07 00:00:00