[Bronchoscopic diagnosis of lung malignancies.].

Abstract:

OBJECTIVE:To assess the diagnostic yield of fiberoptic bronchoscopy in patients with a variety of radiographic findings suspected of malignancy. MATERIAL AND METHODS:The study group was composed of all patients who underwent bronchoscopy in our hospital over a seven year period (1986-1993) where cytologic samples were obtained. Schematic drawings of endobronchial and radiographic findings done at the time of bronchoscopy were reviewed and the results of cytologic and histologic samples were compared for sensitivity and diagnostic accuracy. RESULTS:Bronchoscopy and cytologic sampling was performed on 189 patients. Tissue samples were obtained in 109 patients from visible endobronchial abnormalities or peripheral lesions using the transbronchial approach with fluoroscopic guidance. A total of 64 malignancies were diagnosed, 43 by bronchoscopy (67%). Among 58 patients who had primary malignancy of the lung, adenocarcinoma was the most frequent histologic type (50%) followed by squamous cell carcinoma (22%) and small cell carcinoma (17%). The diagnostic sensitivity of cytology was 30% whereas that of tissue biopsy was 70% among those patients where both tests were obtained. The two methods complemented each other to give a joint sensitivity of 76%. Among 13 patients with malignancy and normal endobronchial appearance, transbronchial biopsy was performed in 10 of which seven were diagnostic. Patients with primary malignancy who underwent surgery had a five year survival of 37% while the overall five year survival was 15.5%. CONCLUSIONS:In this study histology was much more sensitive than cytology as a sampling technique during bronchoscopy (p< 0.01). Adenocarcinoma has become the most frequent histologic type of primary lung malignancy in Iceland and overall survival among patients with primary tumors compares with recent international trends.

journal_name

Laeknabladid

journal_title

Laeknabladid

authors

Magnason S,Isaksson HJ,Bjornsson S,Jonsson S

subject

Has Abstract

pub_date

1999-07-01 00:00:00

pages

610-5

issue

7

eissn

0023-7213

issn

1670-4959

journal_volume

85

pub_type

杂志文章
  • [Diseases in the esophagus, stomach and duodenum: is Helicobacter pylori to blame?].

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    doi:

    authors: Bjœrnsson B,Oervar K,Theodórs A

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  • [Long-term survival of patients with acute myocardial infarction in Iceland].

    abstract:INTRODUCTION:Despite the decreasing incidence rate of acute coronary syndromes worldwide, the incidence of NSTEMI (Non- ST elevation myocardial infarction) has increased relative to STEMI (ST elevation myocardial infarction). The aim of this study was to compare long-term survival rates of NSTEMI and STEMI patients and...

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    authors: Snorrason EL,Johannnesdottir BK,Aspelund T,Gudnason V,Andersen K

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  • [Treatment of hepatitis C with peginterferon and ribavirin in Iceland from 2002-2012].

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    authors: Fridriksson B,Bergmann OM,Olafsson S

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  • [Psychiatric epidemiological research in Iceland].

    abstract::Epidemiological studies of mental disorders in Iceland have a long tradition. The first study was carried out 150 years ago. The results of some of these studies are reviewed to illustrate the uses of epidemiolgy. According to the results of the first study in 1839-1841 mental disorders seemed to be more prevalent in ...

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    authors: Helgason T

    更新日期:1994-04-01 00:00:00

  • [Late and long-term effects of leukaemia treatment in childhood.].

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    doi:

    authors: Kristinsson VH,Kristinsson JR,Jónmundsson GK,Jónsson OG,Thornórsson AV,Haraldsson A

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  • [The prevalence of sicca symptoms in Iceland.].

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    journal_title:Laeknabladid

    pub_type: 杂志文章

    doi:

    authors: Atladóttir J,Guðmundsson OG,Holbrook P,Sigurðsson R,Gudbjornsson B

    更新日期:2000-12-01 00:00:00

  • [Enuresis amongst schoolchildren in an Icelandic town.].

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    pub_type: 杂志文章

    doi:

    authors: Johannsdottir IM,Stefansson ML

    更新日期:1996-12-01 00:00:00

  • [Cost- effectiveness analysis of pneumococcal vaccination in Iceland].

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    journal_title:Laeknabladid

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    doi:10.17992/lbl.2010.09.314

    authors: Björnsdóttir M

    更新日期:2010-09-01 00:00:00

  • [Occupational accidents in Icelandic farmers. Risk factor analysis using questionnaire].

    abstract:BACKGROUND:There is limited information on occupational injuries among Icelandic farmers. It has been suggested that they are common. This is thought to be in part because of the unique work environment of farmers. The aims of the study were to study occupational accidents among farmers and their effects on absence fro...

    journal_title:Laeknabladid

    pub_type: 杂志文章

    doi:

    authors: Gudmundsson G,Tomasson K

    更新日期:2009-12-01 00:00:00

  • [Migraine-related stroke. Two case-reports.].

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    journal_title:Laeknabladid

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    doi:

    authors: Eliasson JH,Valdimarsson EM,Jonsdottir B,Jakobsson F

    更新日期:1998-02-01 00:00:00

  • [Not all wheezing is asthma. Case report].

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    journal_title:Laeknabladid

    pub_type: 杂志文章

    doi:

    authors: Pórarinsson BL,Jónasson L,Jónsdóttir B,Guethmundsson G

    更新日期:2007-01-01 00:00:00

  • [Effects of rehabilitation on functional capacity, obesity and health behavior, among cardiac patients with DM2].

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  • [Extremely Low Birthweight Infants in Iceland. Health and development.].

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    journal_title:Laeknabladid

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    doi:

    authors: Georgsdóttir I,Sæmundsen E,Símonardóttir I,Halldórsson JG,Egilson ST,Leósdóttir T,Ingvarsdóttir B,Sindrason E,Dagbjartsson A

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    journal_title:Laeknabladid

    pub_type: 杂志文章

    doi:

    authors: Magnúsdóttir S,Sighvatsdóttir E

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  • [Sudden noncardiac arrest out-of-hospital in the Reykjavík area 1987-1999.].

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    pub_type: 杂志文章

    doi:

    authors: Marelsson S,Thornorgeirsson G

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  • [The prevalence of fibromyalgia and chronic widespread musculoskeletal pain in Iceland.].

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    doi:

    authors: Birgisson H,Jonsson H,Geirsson AJ

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  • [Closed needle pleural biopsy in Iceland 1990-1999.].

    abstract:OBJECTIVE:Closed pleural biopsy is done to determine causes of pleural effusion after fluid analysis has been nondiagnostic. The aim of the study was to evaluate results of closed pleural biopsy in Iceland. MATERIAL AND METHODS:All pathology reports of closed pleural biopsy from 1990-1999 at the Department of Patholog...

    journal_title:Laeknabladid

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    doi:

    authors: Einarsson JG,Isaksson HJ,Guðmundsson G

    更新日期:2003-03-01 00:00:00

  • [Role of Thrombectomy in Acute Ischemic Stroke].

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    doi:10.17992/lbl.2018.01.169

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  • [Caroli's disease, case report and review of the literature].

    abstract::In 1958 Caroli described a rare disease with multifocal, segmental and saccular dilation of the large intrahepatic bile ducts which causes stagnation of bile and formation of bile sludge and stones. This results in recurrent abdominal pain, cholangitis and hepatic abscesses. The diagnosis is confirmed with endoscopic ...

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    doi:

    authors: Agustsson AI,Cariglia N

    更新日期:2007-09-01 00:00:00

  • [Endocarditis in Iceland 2000-2009, a national survey incidence, microbiology and prognosis].

    abstract:INTRODUCTION:The objective of this study was to analyze the incidence, clinical features, microbiology and prognosis of patients with infective endocarditis (IE) in Iceland, and to compare the results with a previous study made in Iceland 1976-85. MATERIAL AND METHODS:A retrospective study including all patients diagn...

    journal_title:Laeknabladid

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    doi:10.17992/lbl.2012.01.409

    authors: Tryggvadóttir EB,Agnarsson UT,Sverrisson JT,Thorsteinsson SB,Högnason JV,Thorgeirsson G

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  • [Anorexia nervosa in psychiatric units in Iceland 1983-2008, incidence of admissions, psychiatric comorbidities and mortality].

    abstract:OBJECTIVE:Information is scarce concerning the incidence of anorexia nervosa (AN) in psychiatric facilities in Iceland. The aim of this study was to describe the incidence of admissions, comorbidity and mortality of patients who were admitted to psychiatric units in Iceland, diagnosed with AN in 1983-2008. MATERIAL AN...

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    doi:10.17992/lbl.2010.12.331

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    doi:

    authors: Jensdóttir JO,Sigurethsson EL,Thornorgeirsson G

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  • [The treatment of arterial hypertension in elderly men in Iceland].

    abstract::The choice of antihypertensive therapy in elderly Icelanders is unknown. In the database of the Icelandic Heart Association 1145 men, aged 70-84 were alive in 1994. Eight hundred thirty-four came to the Heart Association Clinic, 429 of whom either had hypertension or were found to be hypertensive on examination. The p...

    journal_title:Laeknabladid

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    doi:

    authors: Sigurdardottir V,Einarsson B,Sigfusson N,Harðarson T

    更新日期:1994-12-01 00:00:00

  • [Breakthrough in research on pluripotent stem cells and their application in medicine].

    abstract::Embryonic stem cells are, as the name indicates, isolated from embryos. They are pluripotent cells which can be maintained undifferentiated or induced to differentiate into any cell type of the body. In 1998 the first isolation of human embryonic stem cells was successful and they became an interesting source for stem...

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    authors: Valdimarsdóttir G,Richter A

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    journal_title:Laeknabladid

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    doi:

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  • [Health and performance consequences of Relative Energy Deficiency in Sport (RED-s)].

    abstract::Fulfilling individual energy and nutrient requirements is of great importance for athletes to support overall health and well-being, training adaptation, recovery and injury prevention. Energy availability is the amount of energy left over and available for bodily functions after the energy expended for training is su...

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    pub_type: 杂志文章

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    journal_title:Laeknabladid

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    doi:10.17992/lbl.2010.10.320

    authors: Viktorsdóttir MB,Jónsson E,Einarsdóttir H

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    abstract:OBJECTIVE:The goal of the study was to evaluate the effect and safety of CSII treatment in individuals 18 years and older with type 1 diabetes mellitus in Iceland. METHODS:The research is retrospective. We gathered information from patient data of 40 individuals, age 19-57 years who had been treated with CSII in Icela...

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