Abstract:
:Embryonic stem cells are, as the name indicates, isolated from embryos. They are pluripotent cells which can be maintained undifferentiated or induced to differentiate into any cell type of the body. In 1998 the first isolation of human embryonic stem cells was successful and they became an interesting source for stem cell regenerative medicine. Only 8 years later pluripotent stem cells were generated by reprogramming somatic cells into induced pluripotent stem cells (iPSCs). This was a revolution in the way people thought of cell commitment during development. Since then, a lot of research has been done in understanding the molecular biology of pluripotent stem cells. iPSCs can be generated from somatic cells of a patient and therefore have the same genome. Hence, iPSCs have great potential application in medicine, as they can be utilized in disease modelling, drug screening and cell replacement therapy.
journal_name
Laeknabladidjournal_title
Laeknabladidauthors
Valdimarsdóttir G,Richter Adoi
10.17992/lbl.2015.12.56subject
Has Abstractpub_date
2015-12-01 00:00:00pages
581-6issue
12eissn
0023-7213issn
1670-4959journal_volume
101pub_type
杂志文章,评审相关文献
Laeknabladid文献大全abstract:INTRODUCTION:Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system which affects young people, especially women. The aim of the study was to examine the disease profile of MS during pregnancy and postpartum as well as pregnancy outcomes in women with MS compared to a control group. Suc...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2020.12.612
更新日期:2020-01-01 00:00:00
abstract:INTRODUCTION:Elderly people are a rising population in Iceland. With higher age the likelihood of drug consumption increases and thus drug therapy problems. Pharmaceutical care has been established abroad, where the pharmacist works in collaboration with other healthcare professionals to reduce patients' drug therapy p...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2017.11.159
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVE:Pneumococcus is a common cause of disease among children and the elderly. With the emergence of resistant serotypes, antibiotic treatment is getting limited. Many countries have therefore introduced a vaccination program among children against the most common serotypes. The aim of this study was to analyse co...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2010.09.314
更新日期:2010-09-01 00:00:00
abstract::Body dysmorphic disorder (BDD) is a relatively common disorder characterized by a preoccupation with nonexistent or slight defects in appearance. BDD usually begins during childhood or adolescence. The preoccupation with the perceived appearance defect typically occurs for many hours a day and is often followed by rep...
journal_title:Laeknabladid
pub_type: 杂志文章,评审
doi:10.17992/lbl.2019.03.222
更新日期:2019-03-01 00:00:00
abstract::Recent surveys on the parasites of household cats and dogs in Iceland have revealed the zoonotic protozoans Cryptosporidium parvwn and Toxoplasma gondii and the zoonotic nematodes Toxocara cati and T. canis. Furthermore, a Giardia sp., recently found in cats in Iceland, is also suspected to be a zoonotic parasite. In ...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:1996-09-01 00:00:00
abstract:INTRODUCTION:The treatment of childhood leukemia has improved substantially over the last decades and now 65-75% of the patients recover. With increasing number of survivors it is important to know the long-term and late effects of leukemia and leukaemia treatment. PATIENTS:Of the 31 children diagnosed with leukemia i...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract::Chronic non-communicable diseases (NCDs) are the cause of 86% of all deaths in the EU and 65% of deaths worldwide. A third of these deaths occur before the age of sixty years. The NCDs affect 40% of the adult population of the EU and two thirds of the population reaching retirement age suffers from two or more NCDs. T...
journal_title:Laeknabladid
pub_type: 杂志文章,评审
doi:10.17992/lbl.2012.11.462
更新日期:2012-11-01 00:00:00
abstract:OBJECTIVE:The objective of the research was to estimate the prevalence and treatment of climacteric symptoms among 50 years old women, including which doctors are prescribing the hormone replacement treatment (HRT) and what information is given about the risk and benefit of HRT. MATERIAL AND METHODS:All (n=956) 50 yea...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2000-07-01 00:00:00
abstract::Diseases which result in respiratory failure or hypotension are the most common cause of cardiac arrest in children. Whereas heart diseases are the most common cause of cardiac arrest in adults, they are uncommon cause in children. Accidents are the most common cause of out-of-hospital cardiac arrest. Prompt and skill...
journal_title:Laeknabladid
pub_type: 杂志文章,实务指引
doi:
更新日期:2006-11-01 00:00:00
abstract:INTRODUCTION:Sport participation has increased during the past few decades, with accompanying rise in sport injuries. The purpose of this study was to assess the prevalence of sport injuries, and drop-out due to them along with possible risk factors (hours of sports participation, sex, age, aerobic fitness and body com...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2015.10.45
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:Oesophageal atresia is an congenital anomali with incidence of 1/3000-1/4500 live births. The results of reconstructive surgery has improved greatly, to 80-92% survival reported in the last two decades. The aim of this study was to determine the incidence of oesophageal atresia in Iceland and to evaluate the ...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2004-09-01 00:00:00
abstract::A young competitive swimmer consulted a physician because of respiratory symptoms. He was found to have a normal spirometry. Bronchial asthma was diagnosed based on bronchial challenge test and appropriate treatment started. An overview is given on the rules of the National Sports Association on the treatment of asthm...
journal_title:Laeknabladid
pub_type: 杂志文章,评审
doi:10.17992/lbl.2013.02.483
更新日期:2013-02-01 00:00:00
abstract::IAim The incidence of hepatitis A (HAV) in Iceland is low with about one case per year in the last decades. Since 2016, there has been an ongoing outbreak of HAV in men who have sex with men (MSM). The aim of this study was to inves-tigate whether cases diagnosed in Iceland during 2017 had any link to the HAV outbreak...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2018.06.188
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVE:The evaluation of a vocational rehabilitation programme initiated by the State Social Security Institute in Iceland (SSSI) in 1999 with the aim of reducing disability. MATERIAL AND METHODS:New disability claimants who had been unable to work because of illness for a few months at least were referred by SSSI ...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2002-05-01 00:00:00
abstract:INTRODUCTION:Corporal punishment and abuse of children can have a negative impact on their health and well-being. The aim is to examine on Icelandic adults, experience of corporal punishment as children, its prevalence, justification as victims, and its impact on the assessment of their upbringing. MATERIALS AND METHO...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2013.05.496
更新日期:2013-05-01 00:00:00
abstract::Testicular cancer is the most common cancer diagnosed in males aged 20 to 34 in Iceland. A retrospective population-based study was carried out on all Icelandic males diagnosed between 1971 and 1990 to evaluate presentation and survival of seminoma in Iceland. Fortyseven males with average age of 36 years (range 21-71...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:1996-03-01 00:00:00
abstract::Lung transplantation is an option in the treatment of end stage lung diseases, excluding lung cancer, that lead to short life expectancy and poor quality of life. Now they are mostly limited by shortage of donor organs and longterm complications. They are used for various lung diseases such as pulmonary vascular disea...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2000-09-01 00:00:00
abstract:INTRODUCTION:Persistent physical symptoms that are medically unexplained can result in significant functional impairment. The aim of this study was to estimate the prevalence of persistent physical symptoms among people seeking primary healthcare in Reykjavík, Iceland, how they relate to functional impairment, symptoms...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2021.02.620
更新日期:2021-02-01 00:00:00
abstract:UNLABELLED:Sexually transmitted Chlamydia infection is the most common venereal disease in Iceland. Although considerable information is available on the epidemiology of these infections, the true prevalence of C. trachomatis infections in Iceland is unknown because all the studies have been conducted on selected popul...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:1995-07-01 00:00:00
abstract::Those elderly living in institutions have multiple social, health and mental problems, in addition to loss of function. The Resident Assessment Instrument assesses the individual in detail and his caring needs. Resident Assessment Protocols come with the instrument and a handbook that describes how to evaluate specifi...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:1997-10-01 00:00:00
abstract::Idiopathic vasculitides are systemic inflammatory diseases of vessels, chiefly arteries, of all sizes. The etiology of most vasculitides is unknown. Some are infectious, others involve the deposition of circulating immune complexes in vessel walls. Diagnosis is a composite of clinical symptoms and signs, serologies, h...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract:OBJECTIVE:Information on surgical outcome of aortic valve replacement (AVR) has not been available in Iceland. We therefore studied the indications, short-term complications and operative mortality in Icelandic patients that underwent AVR with aortic stenosis. MATERIAL AND METHODS:This was a retrospective study includ...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2011-10-01 00:00:00
abstract::The choice of antihypertensive therapy in elderly Icelanders is unknown. In the database of the Icelandic Heart Association 1145 men, aged 70-84 were alive in 1994. Eight hundred thirty-four came to the Heart Association Clinic, 429 of whom either had hypertension or were found to be hypertensive on examination. The p...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:1994-12-01 00:00:00
abstract:BACKGROUND:There is limited information on occupational injuries among Icelandic farmers. It has been suggested that they are common. This is thought to be in part because of the unique work environment of farmers. The aims of the study were to study occupational accidents among farmers and their effects on absence fro...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2009-12-01 00:00:00
abstract::A 49 year old previously healthy smoker was diagnosed with a giant bulla in his right lung, following a history of dry cough, repeated upper airway infections and increasing dyspnea for several years. Computed tomography (CT) confirmed the presence of a giant bulla in the right inferior lobe and several smaller bullae...
journal_title:Laeknabladid
pub_type: 杂志文章,评审
doi:
更新日期:2008-10-01 00:00:00
abstract:OBJECTIVE:To describe the changes in the epidemiology of acute epiglottitis in Iceland from 1983-2005. METHODS:All patients with discharge diagnosis of epiglottitis during the study years were identified and diagnosis confirmed by chart review. Main outcome measures were age, gender, month/year of diagnosis, microbiol...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2010.06.300
更新日期:2010-06-01 00:00:00
abstract:INTRODUCTION:Formal referrals to medical specialists have not been required in Iceland since 1984. In 2006, however, referrals were required for patients to receive reimbursement for cardiologists fees. We studied patients' experiences and opinions on the referral process and explored the potential for quality improvem...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2010.05.293
更新日期:2010-05-01 00:00:00
abstract::Enuresis is defined as uncontrolled voiding during day or night after normal control is expected. It is a common disorder, which can be divided into primary and secondary. We looked at the health files from children born between 1986-1988, written when they started school. There were 62 children which were said to hav...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:1996-12-01 00:00:00
abstract:INTRODUCTION:Antibiotic use is a leading cause of antibiotic resistance and it is therefore important to reduce unnecessary prescribing in Iceland where antibiotic use is relatively high. The purpose of this study was to explore antibiotic prescribing practices among Icelandic physicians and compare the results with re...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2016.01.61
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:To analyze the epidemiology of Kawasaki disease in Icelandic children and its complications. METHODS:A retrospective analysis of all cases of Kawasaki disease and atypical Kawasaki disease in children in Iceland from 1996-2005. Chart records were reviewed and children diagnosed at Landspítali - University Ho...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2012.02.414
更新日期:2012-02-01 00:00:00