[Breakthrough in research on pluripotent stem cells and their application in medicine].

Abstract:

:Embryonic stem cells are, as the name indicates, isolated from embryos. They are pluripotent cells which can be maintained undifferentiated or induced to differentiate into any cell type of the body. In 1998 the first isolation of human embryonic stem cells was successful and they became an interesting source for stem cell regenerative medicine. Only 8 years later pluripotent stem cells were generated by reprogramming somatic cells into induced pluripotent stem cells (iPSCs). This was a revolution in the way people thought of cell commitment during development. Since then, a lot of research has been done in understanding the molecular biology of pluripotent stem cells. iPSCs can be generated from somatic cells of a patient and therefore have the same genome. Hence, iPSCs have great potential application in medicine, as they can be utilized in disease modelling, drug screening and cell replacement therapy.

journal_name

Laeknabladid

journal_title

Laeknabladid

authors

Valdimarsdóttir G,Richter A

doi

10.17992/lbl.2015.12.56

subject

Has Abstract

pub_date

2015-12-01 00:00:00

pages

581-6

issue

12

eissn

0023-7213

issn

1670-4959

journal_volume

101

pub_type

杂志文章,评审
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  • [Pharmaceutical Care at the primary care clinic in Garðabær - number and type of drug therapy problems identified among elderly clients].

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    abstract::Body dysmorphic disorder (BDD) is a relatively common disorder characterized by a preoccupation with nonexistent or slight defects in appearance. BDD usually begins during childhood or adolescence. The preoccupation with the perceived appearance defect typically occurs for many hours a day and is often followed by rep...

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  • [Zoonotic parasites of cats and dogs found in playground sandboxes in the Reykjavik area, Iceland.].

    abstract::Recent surveys on the parasites of household cats and dogs in Iceland have revealed the zoonotic protozoans Cryptosporidium parvwn and Toxoplasma gondii and the zoonotic nematodes Toxocara cati and T. canis. Furthermore, a Giardia sp., recently found in cats in Iceland, is also suspected to be a zoonotic parasite. In ...

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    pub_type: 杂志文章

    doi:

    authors: Smaradottir H,Skirnisson K

    更新日期:1996-09-01 00:00:00

  • [Late and long-term effects of leukaemia treatment in childhood.].

    abstract:INTRODUCTION:The treatment of childhood leukemia has improved substantially over the last decades and now 65-75% of the patients recover. With increasing number of survivors it is important to know the long-term and late effects of leukemia and leukaemia treatment. PATIENTS:Of the 31 children diagnosed with leukemia i...

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    doi:

    authors: Kristinsson VH,Kristinsson JR,Jónmundsson GK,Jónsson OG,Thornórsson AV,Haraldsson A

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  • [Chronic non-communicable diseases: a global epidemic of the 21st century].

    abstract::Chronic non-communicable diseases (NCDs) are the cause of 86% of all deaths in the EU and 65% of deaths worldwide. A third of these deaths occur before the age of sixty years. The NCDs affect 40% of the adult population of the EU and two thirds of the population reaching retirement age suffers from two or more NCDs. T...

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    pub_type: 杂志文章,评审

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  • [Climateric symptoms and hormone replacement treatment among 50 years old Icelandic women.].

    abstract:OBJECTIVE:The objective of the research was to estimate the prevalence and treatment of climacteric symptoms among 50 years old women, including which doctors are prescribing the hormone replacement treatment (HRT) and what information is given about the risk and benefit of HRT. MATERIAL AND METHODS:All (n=956) 50 yea...

    journal_title:Laeknabladid

    pub_type: 杂志文章

    doi:

    authors: Benediktsdóttir B,Tómasson K,Gíslason T

    更新日期:2000-07-01 00:00:00

  • [Pediatric life support].

    abstract::Diseases which result in respiratory failure or hypotension are the most common cause of cardiac arrest in children. Whereas heart diseases are the most common cause of cardiac arrest in adults, they are uncommon cause in children. Accidents are the most common cause of out-of-hospital cardiac arrest. Prompt and skill...

    journal_title:Laeknabladid

    pub_type: 杂志文章,实务指引

    doi:

    authors: Thornórkelsson T,Bjoernsson HM,Sigfússon G,International Liaison Committee on Resuscitation (ILCOR).

    更新日期:2006-11-01 00:00:00

  • [Prevalence of sport injuries, sport participation and drop out due to injury in young adults].

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    journal_title:Laeknabladid

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  • [Oesophageal atresia in Iceland 1963-2002; Incidence outcome.].

    abstract:OBJECTIVE:Oesophageal atresia is an congenital anomali with incidence of 1/3000-1/4500 live births. The results of reconstructive surgery has improved greatly, to 80-92% survival reported in the last two decades. The aim of this study was to determine the incidence of oesophageal atresia in Iceland and to evaluate the ...

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    pub_type: 杂志文章

    doi:

    authors: Gunnarsdóttir A,Bjarnason G,Haraldsson A

    更新日期:2004-09-01 00:00:00

  • [Case report: respiratory symptoms in a competitive swimmer].

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    pub_type: 杂志文章,评审

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    authors: Gudmundsson G

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  • [European outbreak of Hepatitis A in Iceland in 2017. Common radiological changes of the gallbladder].

    abstract::IAim The incidence of hepatitis A (HAV) in Iceland is low with about one case per year in the last decades. Since 2016, there has been an ongoing outbreak of HAV in men who have sex with men (MSM). The aim of this study was to inves-tigate whether cases diagnosed in Iceland during 2017 had any link to the HAV outbreak...

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    abstract:OBJECTIVE:The evaluation of a vocational rehabilitation programme initiated by the State Social Security Institute in Iceland (SSSI) in 1999 with the aim of reducing disability. MATERIAL AND METHODS:New disability claimants who had been unable to work because of illness for a few months at least were referred by SSSI ...

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    doi:

    authors: Thorlacius S,Guðmundsson GK,Jónsson FH

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  • [Experience of Icelandic adults of corporal punishment and abuse in childhood].

    abstract:INTRODUCTION:Corporal punishment and abuse of children can have a negative impact on their health and well-being. The aim is to examine on Icelandic adults, experience of corporal punishment as children, its prevalence, justification as victims, and its impact on the assessment of their upbringing. MATERIALS AND METHO...

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  • [Good survival of Icelandic men diagnosed with testicular seminoma between 1971 and 1990 - A retrospective study.].

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  • [Lung transplantation.].

    abstract::Lung transplantation is an option in the treatment of end stage lung diseases, excluding lung cancer, that lead to short life expectancy and poor quality of life. Now they are mostly limited by shortage of donor organs and longterm complications. They are used for various lung diseases such as pulmonary vascular disea...

    journal_title:Laeknabladid

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    doi:

    authors: Guðmundsson G

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  • [Prevalence of persistent physical symptoms and association with depression, anxiety and health anxiety in Iceland].

    abstract:INTRODUCTION:Persistent physical symptoms that are medically unexplained can result in significant functional impairment. The aim of this study was to estimate the prevalence of persistent physical symptoms among people seeking primary healthcare in Reykjavík, Iceland, how they relate to functional impairment, symptoms...

    journal_title:Laeknabladid

    pub_type: 杂志文章

    doi:10.17992/lbl.2021.02.620

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  • [Prevalence of genital chlamydia trachomatis infections in college students.].

    abstract:UNLABELLED:Sexually transmitted Chlamydia infection is the most common venereal disease in Iceland. Although considerable information is available on the epidemiology of these infections, the true prevalence of C. trachomatis infections in Iceland is unknown because all the studies have been conducted on selected popul...

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    authors: Davidsson S,Olafsson JH,Karlsson SM,Kristinsson KG,Steingrimsson O

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    authors: Jonsson PV,Jensdottir AB,Gudmundsdottir H,Palsson H,Hjaltadottir I,Hardarson O,Sigurgeirsdottir S

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  • [Idiopathic vasculitides.].

    abstract::Idiopathic vasculitides are systemic inflammatory diseases of vessels, chiefly arteries, of all sizes. The etiology of most vasculitides is unknown. Some are infectious, others involve the deposition of circulating immune complexes in vessel walls. Diagnosis is a composite of clinical symptoms and signs, serologies, h...

    journal_title:Laeknabladid

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    doi:

    authors: Bjornsson J

    更新日期:1995-01-01 00:00:00

  • [Aortic valve replacement for aortic stenosis in Iceland 2002-2006: Indications and short term complications].

    abstract:OBJECTIVE:Information on surgical outcome of aortic valve replacement (AVR) has not been available in Iceland. We therefore studied the indications, short-term complications and operative mortality in Icelandic patients that underwent AVR with aortic stenosis. MATERIAL AND METHODS:This was a retrospective study includ...

    journal_title:Laeknabladid

    pub_type: 杂志文章

    doi:

    authors: Ingvarsdóttir IL,Viktorsson SA,Hreinsson K,Sigurdsson MI,Helgadóttir S,Arnórsson P,Danielsen R,Gudbjartsson T

    更新日期:2011-10-01 00:00:00

  • [The treatment of arterial hypertension in elderly men in Iceland].

    abstract::The choice of antihypertensive therapy in elderly Icelanders is unknown. In the database of the Icelandic Heart Association 1145 men, aged 70-84 were alive in 1994. Eight hundred thirty-four came to the Heart Association Clinic, 429 of whom either had hypertension or were found to be hypertensive on examination. The p...

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    doi:

    authors: Sigurdardottir V,Einarsson B,Sigfusson N,Harðarson T

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  • [Occupational accidents in Icelandic farmers. Risk factor analysis using questionnaire].

    abstract:BACKGROUND:There is limited information on occupational injuries among Icelandic farmers. It has been suggested that they are common. This is thought to be in part because of the unique work environment of farmers. The aims of the study were to study occupational accidents among farmers and their effects on absence fro...

    journal_title:Laeknabladid

    pub_type: 杂志文章

    doi:

    authors: Gudmundsson G,Tomasson K

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  • [A 49 year old male with a giant pulmonary bulla--a case report and review of the literature].

    abstract::A 49 year old previously healthy smoker was diagnosed with a giant bulla in his right lung, following a history of dry cough, repeated upper airway infections and increasing dyspnea for several years. Computed tomography (CT) confirmed the presence of a giant bulla in the right inferior lobe and several smaller bullae...

    journal_title:Laeknabladid

    pub_type: 杂志文章,评审

    doi:

    authors: Asgeirsson H,Lúdvíksdóttir D,Kjartansson O,Gudbjartsson T

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  • [Acute epiglottitis in Iceland from 1983-2005].

    abstract:OBJECTIVE:To describe the changes in the epidemiology of acute epiglottitis in Iceland from 1983-2005. METHODS:All patients with discharge diagnosis of epiglottitis during the study years were identified and diagnosis confirmed by chart review. Main outcome measures were age, gender, month/year of diagnosis, microbiol...

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  • [Gatekeeping and referrals from GPs to cardiologists: patients' opinions and registration of information flow].

    abstract:INTRODUCTION:Formal referrals to medical specialists have not been required in Iceland since 1984. In 2006, however, referrals were required for patients to receive reimbursement for cardiologists fees. We studied patients' experiences and opinions on the referral process and explored the potential for quality improvem...

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  • [Enuresis amongst schoolchildren in an Icelandic town.].

    abstract::Enuresis is defined as uncontrolled voiding during day or night after normal control is expected. It is a common disorder, which can be divided into primary and secondary. We looked at the health files from children born between 1986-1988, written when they started school. There were 62 children which were said to hav...

    journal_title:Laeknabladid

    pub_type: 杂志文章

    doi:

    authors: Johannsdottir IM,Stefansson ML

    更新日期:1996-12-01 00:00:00

  • [Change in attitude towards antibiotic prescriptions among Icelandic general practitioners].

    abstract:INTRODUCTION:Antibiotic use is a leading cause of antibiotic resistance and it is therefore important to reduce unnecessary prescribing in Iceland where antibiotic use is relatively high. The purpose of this study was to explore antibiotic prescribing practices among Icelandic physicians and compare the results with re...

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