Abstract:
:Colorectal cancer is the third most common cancer in the Western hemisphere and the incidence increases with increasing age. Most colorectal cancers are localized with or without lymph node metastases. Up to 20% of patients present with metastatic disease, most commonly to the liver. Surgery is the only curative therapy for localized colorectal cancer and adjuvant chemotherapy is usually recommended for patients with lymph node metastases. Surgery, radiation therapy and chemotherapy are the key components of rectal cancer therapy. Selected patients with recurrent and metastatic disease can be salvaged with surgery but chemotherapy remains the mainstay of therapy for advanced colorectal cancer. Substantial progress has been observed in the treatment of metastatic colorectal cancer in recent years.
journal_name
Laeknabladidjournal_title
Laeknabladidauthors
Haraldsdottir S,Einarsdottir HM,Smaradottir A,Gunnlaugsson A,Halfdanarson TRdoi
10.17992/lbl.2014.02.531subject
Has Abstractpub_date
2014-02-01 00:00:00pages
75-82issue
2eissn
0023-7213issn
1670-4959journal_volume
100pub_type
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