Abstract:
OBJECTIVE:Survival of extremely low birthweight infants (BW<1000g) in Iceland has increased in recent years, especially since the availability of surfactant therapy for Respiratory Distress Syndrome of Prematurity. This study was part of a geographically defined national study on survival, health, development and longterm outcome of extremely low birthweight (ELBW) infants in Iceland focusing on health, development and disabilities with reference to a control group. MATERIAL AND METHODS:Information from the National Birth Registry on births in Iceland of ELBW infants weighing 500-999g was collected in two periods 1982-90 and 1991-95, before and after surfactant therapy became available. Information on pregnancy, birth, diseases in the newborn period and later health problems was collected from hospital records. The ELBW infants born in 1991-95 and matched control children were enrolled to a prospective study on longterm health and development. The children undervent medical examinations and developmental testing at 5 years of age in 1996-2001. Comparison was made between the two groups of ELBW infants and between ELBW infants and control children born in 1991-95. RESULTS:In 1982-90 the longterm survival of ELBW infants at 5 years of age was 22% and 52% in 1991-95. In both periods 1982-90 and 1991-95 similar data was found on ELBW infants regarding mothers health, pregnancy, birth and neonatal period. Difference was found in maternal age being significantly higher (p=0.02) and significally more deliveries by cesarian section (p=0.02) in the latter period. The two groups of ELBW infants were similar regarding sex, birthweight and diseases in the newborn period. Comparison between 35 ELBW infants and 55 control children born 1991-95 showed that significantly more mothers of ELBW children smoked during pregnancy (p=0.003) and suffered from various diseases (p=0.001). More ELBW children were born by cesarian section (p=0.001) than control children and their parents reported more longterm health problems regarding astma (p=0.001), convulsions (p=0.001), difficulties in swallowing (p=0.001) and weight gaining (p=0.005). At five years of age significantly more ELBW children born in 1991-95 compared to control children had abnormal general physical examination (p=0.001), neurological examination (p=0.001) and motor skills (p=0.001). Scores on developmental testing were significantly lower (p=0.002). The proportion of ELBW children with disabilities was 16% in 1982-90 and 14% in 1991-95. CONCLUSIONS:The two groups of ELBW infants born in 1982-90 and 1991-95 are similar regarding problems during pregnancy, birth and newborn period. The proportion of children with disabilities is similar in both periods although survival was significantly increased. When compared to matched control children, ELBW children born in 1991-95 suffer significantly more longterm health and developmental problems.
journal_name
Laeknabladidjournal_title
Laeknabladidauthors
Georgsdóttir I,Sæmundsen E,Símonardóttir I,Halldórsson JG,Egilson ST,Leósdóttir T,Ingvarsdóttir B,Sindrason E,Dagbjartsson Asubject
Has Abstractpub_date
2003-07-01 00:00:00pages
575-81issue
7-8eissn
0023-7213issn
1670-4959journal_volume
89pub_type
杂志文章相关文献
Laeknabladid文献大全abstract::Renal Cell Carcinoma (RCC) is by far the most common malignant tumor of the kidney. It is a disease with many faces, known for its clinical diversity and often unpredictable behavior. Less is known about its etiology and risk factors than for most other human cancers. Mortality-to-incidence ratio is higher compared to...
journal_title:Laeknabladid
pub_type: 杂志文章,评审
doi:
更新日期:2007-04-01 00:00:00
abstract::Body dysmorphic disorder (BDD) is a relatively common disorder characterized by a preoccupation with nonexistent or slight defects in appearance. BDD usually begins during childhood or adolescence. The preoccupation with the perceived appearance defect typically occurs for many hours a day and is often followed by rep...
journal_title:Laeknabladid
pub_type: 杂志文章,评审
doi:10.17992/lbl.2019.03.222
更新日期:2019-03-01 00:00:00
abstract::IAim The incidence of hepatitis A (HAV) in Iceland is low with about one case per year in the last decades. Since 2016, there has been an ongoing outbreak of HAV in men who have sex with men (MSM). The aim of this study was to inves-tigate whether cases diagnosed in Iceland during 2017 had any link to the HAV outbreak...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2018.06.188
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVE:To determine the size and main medical and social characteristics of the group of individuals receiving disability benefits in Iceland in December 2002 and compare the results with figures from 1996. MATERIAL AND METHODS:The study includes all those receiving disability benefits on December 1st 2002 and Dece...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract:OBJECTIVE:The goal of the study was to evaluate the effect and safety of CSII treatment in individuals 18 years and older with type 1 diabetes mellitus in Iceland. METHODS:The research is retrospective. We gathered information from patient data of 40 individuals, age 19-57 years who had been treated with CSII in Icela...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2011.05.367
更新日期:2011-05-01 00:00:00
abstract::A young competitive swimmer consulted a physician because of respiratory symptoms. He was found to have a normal spirometry. Bronchial asthma was diagnosed based on bronchial challenge test and appropriate treatment started. An overview is given on the rules of the National Sports Association on the treatment of asthm...
journal_title:Laeknabladid
pub_type: 杂志文章,评审
doi:10.17992/lbl.2013.02.483
更新日期:2013-02-01 00:00:00
abstract:OBJECTIVE:The incidence and types of central nervous system (CNS) defects diagnosed in fetuses and newborns over a 20-year period, 1972-1991, were investigated. Concurrently the effect of prenatal ultrasound screening on the rates of delivered babies with neural tube defects were evaluated. MATERIAL AND METHOD:All CNS...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:1996-07-01 00:00:00
abstract::Hair pulling disorder (HPD; trichotillomania) is characterized by recurrent pulling of hair from the scalp, eyebrows or other parts of the body. Skin picking disorder (SPD) is closely related to HPD and involves re-current picking of the skin. Even though both HPD and SPD are relatively common and potentially severe d...
journal_title:Laeknabladid
pub_type: 杂志文章,评审
doi:10.17992/lbl.2012.03.421
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVE:To determine the prevalence of fibromyalgia and chronic widespread musculoskeletal pain (CWP) in Iceland in two demographic different areas. MATERIAL AND METHODS:Population based prevalence study on 1200 females and 1200 males 18-79 years old in South-West- and South-Iceland. Established musculoskeletal pain...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:1998-09-01 00:00:00
abstract::The prevalence of personality disorders was estimated in a sample of 805 individuals randomly selected from the greater Reykjavik area. The sample consisted of 3 equally large cohorts of persons born in 1931, 1951 and 1971. The individuals were asked to participate in a survey of mental health. Of those contacted, 52%...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2009-03-01 00:00:00
abstract:OBJECTIVE:To evaluate a) how many of symptomatic patients referred for upper endoscopy have active H. pylori infection, b) the correlation between the indications for upper endoscopy and endoscopic diagnosis and c) the association between H. pylori and organic disease in the upper gastrointestinal tract. MATERIAL AND ...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2000-03-01 00:00:00
abstract:OBJECTIVE:Of children diagnosed with cancer, approximately one fourth die of the disease or disease related complications. The aim of this study was to investigate survival and causes of death in children with cancer in Iceland. METHODS:This study is retrospective; population based and includes all children, less than...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2010.11.325
更新日期:2010-11-01 00:00:00
abstract:INTRODUCTION:Good functional performance in elderly people greatly improves their changes of independence and well-being. Conversely, bad functional performance can impair their capability of managing the activities of daily life.. The main goal of this study was to investigate the effects of a 6-months' multimodal tra...
journal_title:Laeknabladid
pub_type: 杂志文章,随机对照试验
doi:10.17992/lbl.2013.0708.504
更新日期:2013-07-01 00:00:00
abstract:OBJECTIVE:This study was conducted to investigate the prevalence of alcohol abuse and dependency among elderly women in Iceland and to make an assessment of the sensitivity and specificity of liver function tests and mean corpuscular volume (MCV) in the diagnosis of alcohol abuse. METHODS:The group was made of 280 wom...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:1997-12-01 00:00:00
abstract::A seventeen year old girl in her first pregnancy had a normal vaginal delivery of a healthy male infant. Afterwards, the placenta was retained and subsequent MRI and ultrasound confirmed placenta increta. There was no history of prior uterine surgery. Conservative treatment with methotrexate was chosen in order to con...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2008-07-01 00:00:00
abstract:OBJECTIVE:To investigate long-term complications and survival following aortic valve replacement (AVR) in patients with aortic stenosis (AS) in Iceland. MATERIAL AND METHODS:Included were 156 patients (average age 71.7 yrs, 64.7% males) that underwent AVR for AS at Landspitali between 2002 and 2006. A mechanical prost...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2011.11.395
更新日期:2011-11-01 00:00:00
abstract::In this article the focus is on the estimation of a likelihood ratio by using software which calculates the risk for trisomy 13, 18 and 21. It is based on the woman s age, crown rump length of the fetus and its nuchal translucency measurement. Examples are given based on different maternal age, previous history and re...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2001-05-01 00:00:00
abstract:INTRODUCTION:Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system which affects young people, especially women. The aim of the study was to examine the disease profile of MS during pregnancy and postpartum as well as pregnancy outcomes in women with MS compared to a control group. Suc...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2020.12.612
更新日期:2020-01-01 00:00:00
abstract::This article discusses endovascular thrombectomy in acute ischemic stroke. This treatment is vascular medicine's most significant leap in years. This treatment is complicated, and various technical aspects are discussed. Close cooperation is required between different specialties since patient selection for treatment ...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2018.01.169
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVE:Pneumococcus is a common cause of disease among children and the elderly. With the emergence of resistant serotypes, antibiotic treatment is getting limited. Many countries have therefore introduced a vaccination program among children against the most common serotypes. The aim of this study was to analyse co...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2010.09.314
更新日期:2010-09-01 00:00:00
abstract::Allergies to antibiotics are reported by 8-14% of the adult population out of which half is thought to be due to penicillins. Women are two thirds of those. It is estimated that 20.000 Icelanders believe they are allergic to beta-lactam drugs. Less than 10% of suspected penicillin allergy can be proved by allergy test...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2008-03-01 00:00:00
abstract:OBJECTIVE:To describe the changes in the epidemiology of acute epiglottitis in Iceland from 1983-2005. METHODS:All patients with discharge diagnosis of epiglottitis during the study years were identified and diagnosis confirmed by chart review. Main outcome measures were age, gender, month/year of diagnosis, microbiol...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2010.06.300
更新日期:2010-06-01 00:00:00
abstract:OBJECTIVE:To assess the diagnostic yield of fiberoptic bronchoscopy in patients with a variety of radiographic findings suspected of malignancy. MATERIAL AND METHODS:The study group was composed of all patients who underwent bronchoscopy in our hospital over a seven year period (1986-1993) where cytologic samples were...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:1999-07-01 00:00:00
abstract:OBJECTIVES:Sjoegren' syndrome is one of the most common inflammatory systemic rheumatic disorders. The syndrome is characterised by tiredness, pain problems and mucosal dryness. The goal of this study is to elucidate the prevalence of sicca symptoms in the Icelandic population and to calculate the preliminary prevalenc...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2000-12-01 00:00:00
abstract::The choice of antihypertensive therapy in elderly Icelanders is unknown. In the database of the Icelandic Heart Association 1145 men, aged 70-84 were alive in 1994. Eight hundred thirty-four came to the Heart Association Clinic, 429 of whom either had hypertension or were found to be hypertensive on examination. The p...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:1994-12-01 00:00:00
abstract:INTRODUCTION:Corporal punishment and abuse of children can have a negative impact on their health and well-being. The aim is to examine on Icelandic adults, experience of corporal punishment as children, its prevalence, justification as victims, and its impact on the assessment of their upbringing. MATERIALS AND METHO...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2013.05.496
更新日期:2013-05-01 00:00:00
abstract::Enuresis is defined as uncontrolled voiding during day or night after normal control is expected. It is a common disorder, which can be divided into primary and secondary. We looked at the health files from children born between 1986-1988, written when they started school. There were 62 children which were said to hav...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:1996-12-01 00:00:00
abstract:BACKGROUND:Viral hepatitis B and C are a major health problem worldwide. The prevalence of these diseases varies throughout the world. In Iceland, the incidence of hepatitis B and C has increased in recent years. At the same time, the number of immigrants from countries where viral hepatitis is endemic, has also increa...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2006-10-01 00:00:00
abstract:OBJECTIVE:To evaluate the medical management and cardiovascular (CV) risk profile of patients with hypertension in general practice in Iceland. METHODS:All patients with the diagnosis of hypertension at the primary health care center Solvangur, providing services for 23.066 inhabitants, made up the study group. Medica...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2006-05-01 00:00:00
abstract:INTRODUCTION:The classical pathophysiological process underlying acute coronary syndromes has been considered to be plaque rup-ture followed by platelet activation and aggregation and subsequent thrombus formation leading to myocardial ischemia and infarction. A substantial number of patients with acute coronary syndro...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2018.05.185
更新日期:2018-01-01 00:00:00