Abstract:
:Renal Cell Carcinoma (RCC) is by far the most common malignant tumor of the kidney. It is a disease with many faces, known for its clinical diversity and often unpredictable behavior. Less is known about its etiology and risk factors than for most other human cancers. Mortality-to-incidence ratio is higher compared to other urologic malignancies, and the malignancy confers adverse prognosis for the majority of patients. At the same time as incidence of RCC has been rising globally, progress has been made in the understanding of the disease, especially within the field of genetics and biological research. Immunotherapies together with tyrosine kinase inhibitors and growth factor/angiogenesis modulators are being developed for patients with advanced disease and improvements have been made in the surgical approach. This, together with increased incidental detection secondary to the widespread use of modern imaging procedures, suggests improved prognosis of these patients in the future. For unknown reasons the incidence of RCC is higher in Iceland than in most other countries, about 30 new cases being diagnosed every year, with 14 deaths due to RCC occurring. This evidence-based article reviews major studies on different aspects of RCC with special emphasis on the epidemiology and clinicopathological presentation of the disease in Iceland.
journal_name
Laeknabladidjournal_title
Laeknabladidauthors
Thoroddsen A,Einarsson GV,Gudbjartsson Tsubject
Has Abstractpub_date
2007-04-01 00:00:00pages
283-97issue
4eissn
0023-7213issn
1670-4959journal_volume
93pub_type
杂志文章,评审相关文献
Laeknabladid文献大全abstract:BACKGROUND:There is limited information on occupational injuries among Icelandic farmers. It has been suggested that they are common. This is thought to be in part because of the unique work environment of farmers. The aims of the study were to study occupational accidents among farmers and their effects on absence fro...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2009-12-01 00:00:00
abstract:INTRODUCTION:Research shows that out-of-pocket health care costs in Iceland and other Western European countries have increased in recent years, and unequal access to health services has been documented. In an attempt to contain out-of-pocket-costs and avoid service inequities, Icelandic health authorities have for a n...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2003-05-01 00:00:00
abstract:OBJECTIVE:Closed pleural biopsy is done to determine causes of pleural effusion after fluid analysis has been nondiagnostic. The aim of the study was to evaluate results of closed pleural biopsy in Iceland. MATERIAL AND METHODS:All pathology reports of closed pleural biopsy from 1990-1999 at the Department of Patholog...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2003-03-01 00:00:00
abstract:OBJECTIVE:During the last decade a new and successful treatment of supraventricular tachycardia - radiofrequency catheter ablations - gained ground. In Iceland this method was first used in 1993, seldom during the first year but with increasing frequency the following year. The aim of this study is to evaluate its succ...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2002-03-01 00:00:00
abstract:OBJECTIVE:Vitamin D plays a key role for children's growth and physical developement, not only by promoting bone health but also by its influence on extraskeletal systems. The Icelandic Directorate of Health recommends a vitamin D concentration in blood of at least 50 nmol/l. The object of this study was to evaluate th...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2020.05.579
更新日期:2020-05-01 00:00:00
abstract::A 49 year old previously healthy smoker was diagnosed with a giant bulla in his right lung, following a history of dry cough, repeated upper airway infections and increasing dyspnea for several years. Computed tomography (CT) confirmed the presence of a giant bulla in the right inferior lobe and several smaller bullae...
journal_title:Laeknabladid
pub_type: 杂志文章,评审
doi:
更新日期:2008-10-01 00:00:00
abstract:OBJECTIVE:To evaluate a) how many of symptomatic patients referred for upper endoscopy have active H. pylori infection, b) the correlation between the indications for upper endoscopy and endoscopic diagnosis and c) the association between H. pylori and organic disease in the upper gastrointestinal tract. MATERIAL AND ...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2000-03-01 00:00:00
abstract:INTRODUCTION:Formal referrals to medical specialists have not been required in Iceland since 1984. In 2006, however, referrals were required for patients to receive reimbursement for cardiologists fees. We studied patients' experiences and opinions on the referral process and explored the potential for quality improvem...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2010.05.293
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND/AIMS:Hepatitis C is a major cause of chronic liver disease and cirrhosis in Western countries. Its treatment aims at eradicating the virus and patients are considered cured if the virus is undetectable by PCR in blood 12-24 weeks after end of treatment (sustained virological response, SVR). The aim of this s...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2017.03.126
更新日期:2017-01-01 00:00:00
abstract:INTRODUCTION:Although acute bacterial meningitis is most common among children, the disease nevertheless poses serious problems in the adult population. However, most clinical overviews of the disease have either focused on children or all age groups combined. SUBJECTS AND METHODS:Information on all patients 5=16 year...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:1995-08-01 00:00:00
abstract::A seventeen year old girl in her first pregnancy had a normal vaginal delivery of a healthy male infant. Afterwards, the placenta was retained and subsequent MRI and ultrasound confirmed placenta increta. There was no history of prior uterine surgery. Conservative treatment with methotrexate was chosen in order to con...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2008-07-01 00:00:00
abstract:OBJECTIVE:Oesophageal atresia is an congenital anomali with incidence of 1/3000-1/4500 live births. The results of reconstructive surgery has improved greatly, to 80-92% survival reported in the last two decades. The aim of this study was to determine the incidence of oesophageal atresia in Iceland and to evaluate the ...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2004-09-01 00:00:00
abstract:INTRODUCTION:Lung transplantation is a treatment option for end-stage lung diseases, excluding lung cancer, when life expectancy is short and quality of life is poor. In most instances pulmonary function and quality of life improves after lung transplantation. Infections and rejection are the most common complications ...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2016.05.80
更新日期:2016-05-01 00:00:00
abstract:UNLABELLED:Sexually transmitted Chlamydia infection is the most common venereal disease in Iceland. Although considerable information is available on the epidemiology of these infections, the true prevalence of C. trachomatis infections in Iceland is unknown because all the studies have been conducted on selected popul...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:1995-07-01 00:00:00
abstract:INTRODUCTION:The European Community Respiratory Health Survey (ECRHS) was the first project embarked on extensive study of geographical difference between countries with regards to asthma and atopy incidence in a young adult population. The same methodology and definitions were used at all study sites. The purpose of t...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2002-12-01 00:00:00
abstract:INTRODUCTION:The classical pathophysiological process underlying acute coronary syndromes has been considered to be plaque rup-ture followed by platelet activation and aggregation and subsequent thrombus formation leading to myocardial ischemia and infarction. A substantial number of patients with acute coronary syndro...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2018.05.185
更新日期:2018-01-01 00:00:00
abstract::This article discusses endovascular thrombectomy in acute ischemic stroke. This treatment is vascular medicine's most significant leap in years. This treatment is complicated, and various technical aspects are discussed. Close cooperation is required between different specialties since patient selection for treatment ...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2018.01.169
更新日期:2018-01-01 00:00:00
abstract::In this article the focus is on the estimation of a likelihood ratio by using software which calculates the risk for trisomy 13, 18 and 21. It is based on the woman s age, crown rump length of the fetus and its nuchal translucency measurement. Examples are given based on different maternal age, previous history and re...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2001-05-01 00:00:00
abstract::This nationwide study describes the short- and longterm outcome of acute myocardial infarction in Iceland 1982-83 prior to the routine use of aspirin and thrombolytic therapy. The material consists of 486 cases of acute myocardial infarction, 390 men and 96 women aged 25-64 years. Death prior to hospitalization occure...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:1996-04-01 00:00:00
abstract:BACKGROUND:In the mid twentieth century gastric cancer was the most common type of cancer in Iceland. In recent decades, however, the incidence rate of gastric cancer has decreased markedly and currently only represents 2-3% of cancer cases. The Laurén classification system classifies adenocarcinoma into two types, int...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2016.03.70
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVE:To study the relationship between neonatal feeding patterns and the emergence of neonatal necrotizing enterocolitis during the epidemic of this disease in Iceland in 1987-1990. MATERIAL AND METHODS:This was a retrospective case-controlled study of 18 newborns that developed neonatal necrotizing enterocolitis...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:1998-03-01 00:00:00
abstract::In Iceland, about 770 strokes can be estimated to occur annually. Until recently no treatment had been shown to be effective for acute and subacute strokes. This may have led to therapeutical nihilism and inconsistency in treatment. In 1995, however, t-PA was shown to improve functional outcome when given within three...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:1999-06-01 00:00:00
abstract:OBJECTIVE:To describe the changes in the epidemiology of acute epiglottitis in Iceland from 1983-2005. METHODS:All patients with discharge diagnosis of epiglottitis during the study years were identified and diagnosis confirmed by chart review. Main outcome measures were age, gender, month/year of diagnosis, microbiol...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2010.06.300
更新日期:2010-06-01 00:00:00
abstract:OBJECTIVE:The evaluation of a vocational rehabilitation programme initiated by the State Social Security Institute in Iceland (SSSI) in 1999 with the aim of reducing disability. MATERIAL AND METHODS:New disability claimants who had been unable to work because of illness for a few months at least were referred by SSSI ...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2002-05-01 00:00:00
abstract:OBJECTIVE:To invesigate the familial risk of prostate cancer in Icelandic males. MATERIAL AND METHODS:In the years 1983 and 1984 a total of 146 Icelandic males were diagnosed with adenocarcinoma of the prostate. Family trees were constructed to the third degree relation (first degree male relatives are father, brother...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:1999-09-01 00:00:00
abstract:UNLABELLED:A fifty six year old woman with history of asthma visited a respiratory specialist. She had been diagnosed with asthma more than a year previously in a primary care clinic. She was treated with inhaled medications without good response. A respiratory specialist diagnosed tracheal narrowing secondary to thyro...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:The goal of the study was to evaluate the effect and safety of CSII treatment in individuals 18 years and older with type 1 diabetes mellitus in Iceland. METHODS:The research is retrospective. We gathered information from patient data of 40 individuals, age 19-57 years who had been treated with CSII in Icela...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2011.05.367
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVE:To investigate long-term complications and survival following aortic valve replacement (AVR) in patients with aortic stenosis (AS) in Iceland. MATERIAL AND METHODS:Included were 156 patients (average age 71.7 yrs, 64.7% males) that underwent AVR for AS at Landspitali between 2002 and 2006. A mechanical prost...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2011.11.395
更新日期:2011-11-01 00:00:00
abstract:OBJECTIVE:This study was conducted to investigate the prevalence of alcohol abuse and dependency among elderly women in Iceland and to make an assessment of the sensitivity and specificity of liver function tests and mean corpuscular volume (MCV) in the diagnosis of alcohol abuse. METHODS:The group was made of 280 wom...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:1997-12-01 00:00:00
abstract:INTRODUCTION:The treatment of childhood leukemia has improved substantially over the last decades and now 65-75% of the patients recover. With increasing number of survivors it is important to know the long-term and late effects of leukemia and leukaemia treatment. PATIENTS:Of the 31 children diagnosed with leukemia i...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00