Abstract:
OBJECTIVE:To invesigate the familial risk of prostate cancer in Icelandic males. MATERIAL AND METHODS:In the years 1983 and 1984 a total of 146 Icelandic males were diagnosed with adenocarcinoma of the prostate. Family trees were constructed to the third degree relation (first degree male relatives are father, brother/s, and son/s, et cetera). Relatives with prostate cancer were found using the centralized Icelandic cancer registry. Expected number of cases was calculated from relatives age and the population risk of the disease. RESULTS:The relative risk of prostate cancer was markedly increased for the first and second degree relatives 1.7 (CI: 1.2-2.3) and 1.5 (CI: 1.1-2.2) respectively. The mean age for the probands was 74 years and there was no significant difference in the cumulative familial risk (first, second and third degree relatives) after dividing the probands into two groups; younger or older than the mean age. CONCLUSIONS:Risk of prostate cancer is significantly elevated in relatives of Icelandic males diagnosed with the disease. Family history is therefore of value in screening for prostate cancer.
journal_name
Laeknabladidjournal_title
Laeknabladidauthors
Jonsson E,Olafsdottir G,Sigvaldason H,Tulinius Hsubject
Has Abstractpub_date
1999-09-01 00:00:00pages
708-10issue
9eissn
0023-7213issn
1670-4959journal_volume
85pub_type
杂志文章相关文献
Laeknabladid文献大全abstract::A seventeen year old girl in her first pregnancy had a normal vaginal delivery of a healthy male infant. Afterwards, the placenta was retained and subsequent MRI and ultrasound confirmed placenta increta. There was no history of prior uterine surgery. Conservative treatment with methotrexate was chosen in order to con...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2008-07-01 00:00:00
abstract::Eight of ten strokes are due to cerebral ischemia, two from cerebal hemorrhage. Stroke is the most common cause of disability, the second commonest cause of dementia and the fourth commonest cause of death in the developed world. The incidence of stroke is 150-200/100.000 individuals/ year. One of every seven individu...
journal_title:Laeknabladid
pub_type: 杂志文章,评审
doi:10.17992/lbl.2014.05.543
更新日期:2014-05-01 00:00:00
abstract:OBJECTIVE:This study was part of a geographically defined national study on survival, health, development, and longterm outcome of extremely low birthweight infants (ELBW; birthweight < 1000g) in Iceland focusing on development and neurodevelopmental measures in comparison to a reference group. METHODS:All 35 ELBW lon...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2004-11-01 00:00:00
abstract::Migraine is the cause of 3-25% of strokes in young adults. Each year we can expect 9-10 cases of migraine-related stroke in Iceland. The most common symptom is hemianopia but other common symptoms include hemiparesis, hemianesthesia, dysphasia and various brain stem symptoms. The stroke must occur during a typical mig...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:1998-02-01 00:00:00
abstract:INTRODUCTION:Formal referrals to medical specialists have not been required in Iceland since 1984. In 2006, however, referrals were required for patients to receive reimbursement for cardiologists fees. We studied patients' experiences and opinions on the referral process and explored the potential for quality improvem...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2010.05.293
更新日期:2010-05-01 00:00:00
abstract:OBJECTIVE:Of children diagnosed with cancer, approximately one fourth die of the disease or disease related complications. The aim of this study was to investigate survival and causes of death in children with cancer in Iceland. METHODS:This study is retrospective; population based and includes all children, less than...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2010.11.325
更新日期:2010-11-01 00:00:00
abstract:BACKGROUND:There is limited information on occupational injuries among Icelandic farmers. It has been suggested that they are common. This is thought to be in part because of the unique work environment of farmers. The aims of the study were to study occupational accidents among farmers and their effects on absence fro...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Increased medical and technical knowledge has saved the lives of more patients than was possible a few decades ago. This has also raised many ethical questions. It is now regarded to be justifiable to limit treatment for some terminally ill patients because certain treatment options are not fel...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:1997-06-01 00:00:00
abstract::Fulfilling individual energy and nutrient requirements is of great importance for athletes to support overall health and well-being, training adaptation, recovery and injury prevention. Energy availability is the amount of energy left over and available for bodily functions after the energy expended for training is su...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2020.09.596
更新日期:2020-09-01 00:00:00
abstract::This article discusses endovascular thrombectomy in acute ischemic stroke. This treatment is vascular medicine's most significant leap in years. This treatment is complicated, and various technical aspects are discussed. Close cooperation is required between different specialties since patient selection for treatment ...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2018.01.169
更新日期:2018-01-01 00:00:00
abstract::Pulmonary arterial hypertension is a rare disease with substantial morbidity and mortality. In the last few years significant progress has been made in the understanding of the pathogenesis and course of the disease. New classification and drug treatment have emerged. The new drugs are expensive but can improve qualit...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2003-12-01 00:00:00
abstract::Renal Cell Carcinoma (RCC) is by far the most common malignant tumor of the kidney. It is a disease with many faces, known for its clinical diversity and often unpredictable behavior. Less is known about its etiology and risk factors than for most other human cancers. Mortality-to-incidence ratio is higher compared to...
journal_title:Laeknabladid
pub_type: 杂志文章,评审
doi:
更新日期:2007-04-01 00:00:00
abstract:OBJECTIVE:To determine the prevalence of fibromyalgia and chronic widespread musculoskeletal pain (CWP) in Iceland in two demographic different areas. MATERIAL AND METHODS:Population based prevalence study on 1200 females and 1200 males 18-79 years old in South-West- and South-Iceland. Established musculoskeletal pain...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:1998-09-01 00:00:00
abstract::Modern tablet compression was instituted in England in 1844 by William Brockedon (1787-1854). The first tablets made according to Brockedon´s procedures contained watersoluble salts and were most likely compressed without expedients. In USA a watershed occurred around 1887 when starch (amylum maydis) was introduced to...
journal_title:Laeknabladid
pub_type: 历史文章,杂志文章
doi:10.17992/lbl.2013.04.493
更新日期:2013-04-01 00:00:00
abstract::During almost four decades neuroleptic drugs have been the main weapon in doctor's armamentarium against schizophrenia and some other major psychiatric disorders. In Iceland seven different depot-neuroleptics from three subgroups are used. The main indication for depot-neuroleptics is to insure that the patient gets t...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the prevalence of psychotropic drug use among home-dwelling elderly Icelanders in the year 2006. MATERIALS AND METHODS:A population-based drug utilization study using the Icelandic Medicines Registry. The study group consisted of Icelanders, seventy years and older living at home (8% of total pop...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract:INTRODUCTION:Persistent physical symptoms that are medically unexplained can result in significant functional impairment. The aim of this study was to estimate the prevalence of persistent physical symptoms among people seeking primary healthcare in Reykjavík, Iceland, how they relate to functional impairment, symptoms...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2021.02.620
更新日期:2021-02-01 00:00:00
abstract:OBJECTIVE:To assess the diagnostic yield of fiberoptic bronchoscopy in patients with a variety of radiographic findings suspected of malignancy. MATERIAL AND METHODS:The study group was composed of all patients who underwent bronchoscopy in our hospital over a seven year period (1986-1993) where cytologic samples were...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:1999-07-01 00:00:00
abstract::Demand for Vocational Rehabilitation in Iceland has been steadily rising in recent years where the presence of young patients has increased proportionally the most. It is essential that public spending is efficient without compromising the treatment quality. It is worth exploring if a solution for increasing the effic...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2019.06.236
更新日期:2019-06-01 00:00:00
abstract::IAim The incidence of hepatitis A (HAV) in Iceland is low with about one case per year in the last decades. Since 2016, there has been an ongoing outbreak of HAV in men who have sex with men (MSM). The aim of this study was to inves-tigate whether cases diagnosed in Iceland during 2017 had any link to the HAV outbreak...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2018.06.188
更新日期:2018-01-01 00:00:00
abstract::Anaemia of uncertain origin is common in elderly people and is reported to be more common in men than women. We have investigated retrospectively a database of haematological and biochemical data on 16.332 people referred to an outpatient laboratory and compared the blood haemoglobin (Hb) concentration of the sexes. I...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:1994-10-01 00:00:00
abstract::Allergies to antibiotics are reported by 8-14% of the adult population out of which half is thought to be due to penicillins. Women are two thirds of those. It is estimated that 20.000 Icelanders believe they are allergic to beta-lactam drugs. Less than 10% of suspected penicillin allergy can be proved by allergy test...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2008-03-01 00:00:00
abstract:OBJECTIVE:To evaluate a) how many of symptomatic patients referred for upper endoscopy have active H. pylori infection, b) the correlation between the indications for upper endoscopy and endoscopic diagnosis and c) the association between H. pylori and organic disease in the upper gastrointestinal tract. MATERIAL AND ...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2000-03-01 00:00:00
abstract:BACKGROUND:Cognitive behavioral therapy (CBT) and SSRI/SNRI antidepressants have proven to be effective treatments for anxiety and depression. The gain from combined CBT and antidepressant therapy has in some studies been greater than from monotherapy. Benzodiazepines may interfere with the efficacy of individual CBT-t...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2013.11.517
更新日期:2013-11-01 00:00:00
abstract:INTRODUCTION:Despite the decreasing incidence rate of acute coronary syndromes worldwide, the incidence of NSTEMI (Non- ST elevation myocardial infarction) has increased relative to STEMI (ST elevation myocardial infarction). The aim of this study was to compare long-term survival rates of NSTEMI and STEMI patients and...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2018.11.203
更新日期:2018-11-01 00:00:00
abstract:INTRODUCTION:The classical pathophysiological process underlying acute coronary syndromes has been considered to be plaque rup-ture followed by platelet activation and aggregation and subsequent thrombus formation leading to myocardial ischemia and infarction. A substantial number of patients with acute coronary syndro...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2018.05.185
更新日期:2018-01-01 00:00:00
abstract:INTRODUCTION:Research shows that out-of-pocket health care costs in Iceland and other Western European countries have increased in recent years, and unequal access to health services has been documented. In an attempt to contain out-of-pocket-costs and avoid service inequities, Icelandic health authorities have for a n...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2003-05-01 00:00:00
abstract:UNLABELLED:A fifty six year old woman with history of asthma visited a respiratory specialist. She had been diagnosed with asthma more than a year previously in a primary care clinic. She was treated with inhaled medications without good response. A respiratory specialist diagnosed tracheal narrowing secondary to thyro...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract::Lung transplantation is an option in the treatment of end stage lung diseases, excluding lung cancer, that lead to short life expectancy and poor quality of life. Now they are mostly limited by shortage of donor organs and longterm complications. They are used for various lung diseases such as pulmonary vascular disea...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:
更新日期:2000-09-01 00:00:00
abstract:OBJECTIVE:Vitamin D plays a key role for children's growth and physical developement, not only by promoting bone health but also by its influence on extraskeletal systems. The Icelandic Directorate of Health recommends a vitamin D concentration in blood of at least 50 nmol/l. The object of this study was to evaluate th...
journal_title:Laeknabladid
pub_type: 杂志文章
doi:10.17992/lbl.2020.05.579
更新日期:2020-05-01 00:00:00