Glucose-lowering effects of 7-day treatment with SGLT2 inhibitor confirmed by intermittently scanned continuous glucose monitoring in outpatients with type 1 diabetes. A pilot study.

abstract：:Immunoglobulin G4-related disease (IgG4-RD) is characterized by elevated serum IgG4 levels, IgG4-positive plasmacytes, and lymphocyte infiltration into multiple organs. IgG4 thyroiditis is a subset of patients with Hashimoto's thyroiditis (HT) who exhibited histopathological features of IgG4-RD; its source of serum Ig...

journal_title：Endocrine journal

authors： Takeshima K,Ariyasu H,Inaba H,Inagaki Y,Yamaoka H,Furukawa Y,Doi A,Furuta H,Nishi M,Akamizu T

更新日期：2015-01-01 00:00:00

abstract：:TSH receptor antibody (TRAb) titer has been reported to be correlated with Graves' ophthalmopathy (GO). However, the correlation between GO activity and TRAb titer assessed with a third-generation assay has not been reported. We enrolled 238 untreated Graves' disease patients who came to the outpatient clinic of Ito H...

journal_title：Endocrine journal

authors： Mukasa K,Yoshimura Noh J,Kouzaki A,Ohye H,Kunii Y,Watanabe N,Yoshihara A,Matsumoto M,Suzuki M,Ito K

更新日期：2016-01-01 00:00:00

abstract：:It has been reported that there is an inverse relationship between serum sodium (Na) and potassium (K) levels in patients with diabetic coma. The present study was undertaken to determine whether such an inverse relation depends upon plasma glucose levels in diabetic patients for their glycemic control. We examined tw...

journal_title：Endocrine journal

authors： Saito T,Ishikawa S,Higashiyama M,Nakamura T,Rokkaku K,Hayashi H,Kusaka I,Nagasaka S,Saito T

更新日期：1999-02-01 00:00:00

abstract：:Musk is a secreted external hormone or information compound that is stored in musk scent glands of the males of species within the family Moschidae, such as Moschus berezovskii. The secretion of musk changes periodically during the courtship and reproduction periods, with the early stage of secretion occurring from Ma...

journal_title：Endocrine journal

authors： Fan M,Zhang M,Shi M,Zhang T,Qi L,Yu J,Li X,Lin S,Huang Z,Yang S,Zhou J,Li Y,Sun X,Cha M,Xu S,Liu Y,Guo X,Hu D,Liu S

更新日期：2018-11-29 00:00:00

abstract：:Administration of monosodium L-glutamate (MSG) to neonatal mice produces a hypothalamic syndrome consisting of stunted growth and later development of obesity. We assayed plasma insulin (IRI), thyroxine (T4) and insulin-like growth factor-I (IGF-I) to investigate their roles in the growth of the mice. Two mg/g body we...

journal_title：Endocrine journal

authors： Yamamoto T,Matsuo S,Ueshima Y,Inoue F,Kinugasa A,Sawada T

更新日期：1993-08-01 00:00:00

abstract：:A previous study reported a high prevalence of autoantibodies to alpha-enolase in lymphocytic hypophysitis and these antibodies efficiently distinguished lymphocytic hypophysitis from pituitary tumors. To confirm this, we examined autoantibodies to alpha-enolase in patients with lymphocytic hypophysitis (n = 17), pitu...

journal_title：Endocrine journal

authors： Tanaka S,Tatsumi KI,Takano T,Murakami Y,Takao T,Yamakita N,Tahara S,Teramoto A,Hashimoto K,Kato Y,Amino N

更新日期：2003-12-01 00:00:00

abstract：:Progression to overt hypothyroidism and the associated adverse effects on lipid metabolism and the cardiovascular system are major concerns for patients diagnosed with subclinical hypothyroidism (SCH). No consensus regarding the clinical parameters associated with prognosis for this mild thyroid dysfunction has yet be...

journal_title：Endocrine journal

authors： Shin DY,Kim EK,Lee EJ

更新日期：2010-01-01 00:00:00

abstract：:The objective of this study was to investigate the effect of administration of recombinant human growth hormone (hGH) in patients with Noonan syndrome. hGH was administered (0.5 IU/kg/week) to 15 patients with Noonan syndrome over a 2 year period. Average patient age prior to therapy was 7.5 +/- 2.5 (mean +/- SD) yr, ...

journal_title：Endocrine journal

authors： Ogawa M,Moriya N,Ikeda H,Tanae A,Tanaka T,Ohyama K,Mori O,Yazawa T,Fujita K,Seino Y,Kubo T,Tanaka H,Nishi Y,Yoshimoto M

更新日期：2004-02-01 00:00:00

abstract：:Since there is increasing evidence that postprandial hyperglycemia is a risk factor for the development of macrovascular complications, it is important to predict postprandial hyperglycemia in the early stages of glucose intolerance, and routine medical checkups provide a good opportunity to do so. The aim of this stu...

journal_title：Endocrine journal

authors： Goto M,Yamamoto-Honda R,Shimbo T,Goto A,Terauchi Y,Kanazawa Y,Noda M

更新日期：2011-01-01 00:00:00

abstract：:Erdheim-Chester disease (ECD) is a form of non-Langerhans histiocytosis. In this report, we show a case of ECD presenting diabetes insipidus and multiple xanthogranulomas received glucocorticoid treatment over a year. During this period, xanthogranulomas improved in response to the glucocorticoid therapy. Furthermore,...

journal_title：Endocrine journal

authors： Taguchi T,Iwasaki Y,Asaba K,Yoshida T,Takao T,Ikeno F,Nakajima H,Kodama H,Hashimoto K

更新日期：2008-03-01 00:00:00

abstract：:Kallmann syndrome is defined by the association of hypogonadotropic hypogonadism and anosmia, for which three modes of transmission have been described: X-linked, autosomal recessive and autosomal dominant. The KAL1 gene, responsible for the X-linked form of the disease, has been isolated and its intron-exon organizat...

journal_title：Endocrine journal

authors： Izumi Y,Tatsumi K,Okamoto S,Hosokawa A,Ueno S,Fukui H,Amino N

更新日期：1999-10-01 00:00:00

abstract：:Kallmann syndrome is defined by the association of hypogonadotropic hypogonadism and anosmia. The KAL1 gene is responsible for the X-linked form of Kallmann syndrome. We analyzed the KAL1 gene in 19 Japanese patients with Kallmann syndrome, including 3 patients reported previously, using PCR-direct sequencing method. ...

journal_title：Endocrine journal

authors： Izumi Y,Tatsumi K,Okamoto S,Ogawa T,Hosokawa A,Matsuo T,Kato Y,Fukui H,Amino N

更新日期：2001-04-01 00:00:00

abstract：:Fructose 2,6-bisphosphate (F2,6BP) is a powerful allosteric activator of 6-phosphofructo-1-kinase, which is the rate-limiting enzyme for glycolysis. Mitogenic stimulation of lymphocytes is related to an enhanced rate of glucose utilization and F2,6BP mediated activation of glycolysis. To determine the effect of hyperg...

journal_title：Endocrine journal

authors： Atsumi T,Chiba H,Yoshioka N,Bucala R,Koike T

更新日期：2007-08-01 00:00:00

abstract：:In each estrous cycle not all follicles recruited grow to ovulate, as some degenerate through the process of atresia. Apoptosis is the mechanism underlying follicle atresia. TGF-beta1 has been implicated in the induction and promotion of apoptosis in many cell types and it is expressed in the ovary. In this study immu...

journal_title：Endocrine journal

authors： Christopher B

更新日期：2000-08-01 00:00:00

abstract：:Methylenetetrahydrofolate reductase plays an important role in folate metabolism. Individuals who are type 2 diabetes mellitus have greatest risk for the development of vascular complications. The results of studies which assessed the association between MTHFR C677T polymorphism and T2DM with vascular complications we...

journal_title：Endocrine journal

authors： Zhang D,Zhou Y,Han L,Ji H,Li J

更新日期：2014-01-01 00:00:00

abstract：:Thyrotoxic periodic paralysis (TPP) is mainly associated with Graves' disease but rarely with autonomously functioning thyroid nodule (AFTN). We herein report a case of AFTN associated with TPP in which the latter resolved after (131) I therapy for the former. We analyzed the genes encoding thyrotropin receptor (TSHR)...

journal_title：Endocrine journal

authors： Ozaki H,Mori K,Nakagawa Y,Hoshikawa S,Ito S,Yoshida K

更新日期：2008-03-01 00:00:00

abstract：:We measured serum levels of the carboxy-terminal propeptide of type 1 procollagen (P1CP) as a marker of bone formation and the carboxy-terminal telopeptide of type 1 collagen (1CTP) as a marker of bone resorption by RIA in sera from 40 Graves' disease patients and 14 Hashimoto's disease patients before and during trea...

journal_title：Endocrine journal

authors： Miyakawa M,Tsushima T,Demura H

更新日期：1996-12-01 00:00:00

abstract：:It seems reasonable to expect that biochemical changes occurring in the pregnant woman with diabetes should be reflected in the placenta structure. However, it has not been possible to correlate placental morphology with glycemic control in a comparison between those with long life diabetes and poorly controlled gesta...

journal_title：Endocrine journal

authors： al-Okail MS,al-Attas OS

更新日期：1994-08-01 00:00:00

abstract：:In this study, we investigated the difference in lymph node-recurrence free survival (LN-RFS), distant recurrence-free survival (DRFS), and cause-specific survival (CSS) between patients with papillary thyroid carcinoma (PTC) in the entire group (Group I) and those with lymph node- and distant-recurrence-free survival...

journal_title：Endocrine journal

authors： Ito Y,Kudo T,Kihara M,Takamura Y,Kobayashi K,Miya A,Miyauchi A

更新日期：2012-01-01 00:00:00

abstract：:Thyrotropin-releasing hormone (TRH)-stimulated thyroid stimulating hormone (TSH) response in normal subjects is suppressed by oral glucose administration. Pharmacologic studies indicate that this suppressive action of glucose is mediated by an increase in hypothalamic somatostatin (SRIH) tone. Since activation of the ...

journal_title：Endocrine journal

authors： Park C,Kim E,Sohn S,Yang I,Koh G,Oh S,Woo J,Kim S,Kim J,Kim Y,Oh K,Park S,Park S

更新日期：2005-02-01 00:00:00

abstract：:Gonadotropin-releasing hormone (GnRH) and its agonists have been known to directly affect steroid hormone production in human granulosa cells. In this study, we examined effects of GnRH on Ca2+ mobilization, protein kinase C activity and steroidogenesis of human granulosa cells. Human granulosa cells were harvested by...

journal_title：Endocrine journal

authors： Hori H,Uemura T,Minaguchi H

更新日期：1998-04-01 00:00:00

abstract：:We report on two siblings with classic simple virilizing 21-hydroxylase deficiency whose neonatal screening for serum 17alpha-hydroxyprogesterone (17-OHP) gave normal results. The proband, a girl with clitoromegaly whose screening 17-OHP value had been 9.2 ng/ml, was diagnosed at the age of 6 months, and her elder bro...

journal_title：Endocrine journal

authors： Shinohara O,Ishiguro H,Shinagawa T,Kubota C

更新日期：1998-06-01 00:00:00

abstract：:Ghrelin is a peptide hormone with a unique structure comprising a medium chain fatty acid modification. Ghrelin cells are known to be abundantly localized in the gastric mucosa and are released into the blood stream to exert their multifunctional physiological effects. To elucidate the regulatory mechanisms of ghrelin...

journal_title：Endocrine journal

authors： Sakata I,Gong Z,Ikenoya C,Takemi S,Sakai T

更新日期：2017-01-01 00:00:00

abstract：:Thyroid dysfunction has been known to be closely associated with increased vascular events. The aims of the present study included determining the prevalence of subclinical thyroid disease and relationships between normal ranges of thyroid function and internal carotid artery steno-occlusion (ICS) in patients with isc...

journal_title：Endocrine journal

authors： Jeong SK,Seo JY,Nam HS,Park HK

更新日期：2010-01-01 00:00:00

abstract：:The purpose of this study is to evaluate the impact of insulin secretion-sensitivity index-2 (ISSI-2) in the identification of the role of pancreatic iron deposition on beta-cell function in thalassemia major. Tissue iron stores were measured with magnetic resonance imaging (MRI) in the liver (R2), pancreas (R2*), and...

journal_title：Endocrine journal

authors： Karadas N,Yurekli B,Bayraktaroglu S,Aydinok Y

更新日期：2019-12-25 00:00:00

abstract：:We demonstrated severe hyponatremia in a 68 year-old man who had pituitary tumor. He had poor appetite and was disoriented. Tests revealed hyponatremia of 110 mmol/l, and he was admitted to Jichi Medical School Omiya Medical Center to undergo further tests. Physical findings revealed disturbance of consciousness with ...

journal_title：Endocrine journal

authors： Kanda M,Omori Y,Shinoda S,Yamauchi T,Tamemoto H,Kawakami M,Ishikawa SE

更新日期：2004-08-01 00:00:00

abstract：:Adult growth hormone deficiency (GHD) is a well defined clinical condition, which is characterized by abnormal body composition, impaired physical activity and decreased quality of life. In addition, in recent years, growing interest has been shown towards cardiovascular risks in adult patients affected by GHD. In thi...

journal_title：Endocrine journal

authors： Giovannini L,Tirabassi G,Muscogiuri G,Di Somma C,Colao A,Balercia G

更新日期：2015-01-01 00:00:00

abstract：:The presence of human progesterone receptor (PR) mRNA variants has been demonstrated in uterine endometrium and breast tissues as well as in cancer cells of these tissues. While exon deletions by the alternative splicing in these variants have been reported, there are few reports available on the PR mRNA variants with...

journal_title：Endocrine journal

authors： Yamanaka T,Hirata S,Shoda T,Hoshi K

更新日期：2002-08-01 00:00:00

abstract：:We provide the details of the successful management of a patient with active Cushing's disease complicated with coronavirus disease 2019 (COVID-19) pneumonia. The patient was a 27-year-old Japanese female healthcare worker who was scheduled to undergo pituitary surgery for Cushing's disease. She had been in close cont...

journal_title：Endocrine journal

authors： Yuno A,Kenmotsu Y,Takahashi Y,Nomoto H,Kameda H,Cho KY,Nakamura A,Yamashita Y,Nakamura J,Nakakubo S,Kamada K,Suzuki M,Sugino H,Inoshita N,Konno S,Miyoshi H,Atsumi T,Sawamura Y,Shimatsu A

更新日期：2020-12-24 00:00:00

abstract：:A 19-year-old girl presented at our emergency room with hypokalemic periodic paralysis. She had a thyrotoxic goiter and had experienced three paralytic attacks during the previous 2 years on occasions when she stopped taking antithyroid drugs. In addition to thyrotoxic periodic paralysis (TPP), she had metabolic acido...

journal_title：Endocrine journal

authors： Im EJ,Lee JM,Kim JH,Chang SA,Moon SD,Ahn YB,Son HS,Cha BY,Lee KW,Son HY

更新日期：2010-01-01 00:00:00