[Clinico-histopathologic correlation of ganciclovir-treated cytomegalovirus retinitis].

Abstract:

:A 46 year old AIDS-patient, who had developed CMV-retinitis was treated with the virostatic drug dihydroxypropoxymethylguanine (DHPG, Ganciclovir) over a period of 16 months until he died due to a pneumonia. After the DHPG-treatment was initiated the retinitis improved markedly, however there still was a very slow progression of the disease in the following time. The central retina of both eyes was not affected until death. Postmortal immunohistochemically CMV-antigen-staining was positive according to the former clinically active retinitis. At the eyes of the retinal necrosis calcified deposits were identified by Kossa-staining; these areas had clinically appeared as yellowish briddle deposits. The clinical course and the immunohistochemical proof of active CMV-virus-particles suggest that DHPG was able to suppress the progression of a CMV-retinitis and to preserve a good visual acuity until death; however a true cure of the CMV-infection could not be achieved.

journal_name

Klin Monbl Augenheilkd

authors

Daus W,Kaps D,Völcker HE

doi

10.1055/s-2008-1046305

subject

Has Abstract

pub_date

1990-11-01 00:00:00

pages

426-31

issue

5

eissn

0023-2165

issn

1439-3999

journal_volume

197

pub_type

杂志文章
  • [Ocular involvement in Whipple disease].

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    doi:10.1055/s-2008-1045480

    authors: Schrenk M,Metz K,Heiligenhaus A,Layer P,Bornfeld N,Wessing A

    更新日期:1994-06-01 00:00:00

  • [A training device for intraocular surgery (author's transl)].

    abstract::Description of a new holder for experimental intraocular surgery on human autopsy eyes. Stability of shape and position of the experimental eyes is achieved by a vacuum surrounding the posterior segment. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Spitznas M

    更新日期:1976-03-01 00:00:00

  • [Blepharospasm treatment with botulinum toxin (follow-up)].

    abstract::Within a period of 14 months 73 patients with idiopathic blepharospasm which could not be treated satisfactorily by any other form of therapy were treated by injections of botulin toxin. In 55 cases the follow-up period was sufficiently long to permit an evaluation. Thirty-five patients were temporarily completely fre...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

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    doi:10.1055/s-2008-1050804

    authors: Roggenkämper P

    更新日期:1986-10-01 00:00:00

  • [Ocular Manifestation of Mucopolysaccharidosis I-S (Scheie's Syndrome)].

    abstract:BACKGROUND:Bilateral stromal corneal opacifications are a differential diagnostical challenge to identify associated systemic diseases. CASE-REPORT:A 47-year old civil engineer (height 167 cm) with bilateral stromal corneal clouding presented with visual loss for the last 27 years: VA 20/100 OD and 20/50 OS (following...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2002-35688

    authors: Viestenz A,Shin YS,Viestenz A,Naumann GO

    更新日期:2002-10-01 00:00:00

  • [Neurological disorders and glaucoma - an overview].

    abstract::Due to the anatomic location of the N. opticus to the brain and its embryological development as a "bulging part of the brain", a close connection between the opticoneuropathy and certain neurological diseases exists. Glaucoma is a chronic neurodegenerative disorder and many cellular and molecular mechanisms of the ch...

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    doi:10.1055/s-0033-1360316

    authors: Göbel K,Erb C

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  • [Erythropsia following exposure to toluene].

    abstract::A patient who had been exposed to toluol for ten years developed acute erythropsia. The examinations leading to the diagnosis and the possible differential diagnosis are discussed. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

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    doi:10.1055/s-2008-1046214

    authors: Prünte-Glowazki A

    更新日期:1990-05-01 00:00:00

  • [Fusion amplitude and aniseikonia. Experimental studies of aniseikonia tolerance in unilateral aphakia].

    abstract::The fusion amplitude of image pairs with aniseikonia was measured using the synoptophore. Aniseikonia was produced in five subjects by alteration of slide drawings. The subject's right eye was in cycloplegia after paralysis with cycloplegic eye drops. To compare these measurements with aniseikonic pictures to those us...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

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    doi:10.1055/s-2008-1050555

    authors: Pittke EC

    更新日期:1987-12-01 00:00:00

  • [Ophthalmological symptoms following extrathoracal reanimation (author's transl)].

    abstract::In patients with cardiac arrest and extrathorakal reanimation, hyposphagma, vitreous and retinal hemorrhages, fat embolism in the retinal arteries as well as fluffy exudates of the fundus were observed. Pathogenesis and connections with Purtscher's traumatic angiopathic retinopathy are discussed. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1057727

    authors: Rochels R,Schmitt EJ

    更新日期:1980-12-01 00:00:00

  • [Results of 1-year use of local pindolol in open-angle glaucoma].

    abstract::In a randomized and controlled study (already published) the efficacy and safety of Pindolol eye drops 1% were compared with Timolol eye drops 0.5% in the treatment of open-angle glaucoma over a period of 6 months. With the exception of some allergic reactions there was no difference between the two with regard to IOP...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1050872

    authors: Stryz JR,Merté HJ

    更新日期:1985-01-01 00:00:00

  • [Possibilities of microsurgery on ophthalmic vessels (author's transl)].

    abstract::Ciliary arteries, isolated from the eyes of human cadavers, were incised or severed under the microscope in order to test the technical possibilities of placing sutures or creating leak-proof anastomoses in ophthalmic vessels. Commercially available, minute atraumatic needles and 10-0 "Ethilon" or 15-0 Supramid suture...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1057589

    authors: Gundorowa RA,Galtschin AS

    更新日期:1980-06-01 00:00:00

  • [Principles of DNA diagnosis].

    abstract::In an ever-increasing number of the more than 4000 known genetic diseases with Mendelian inheritance, the geneloci have been mapped. In such cases it is possible to predict by DNA techniques whether or not family members are carriers of the mutation and risk having affected children. Using the same methods, disease ca...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1046167

    authors: Moser H

    更新日期:1990-05-01 00:00:00

  • [Voluntary control of unilateral strabismus sursoadductorius].

    abstract:BACKGROUND:Strabismus with unilateral elevation in adduction is an upward deviation of the adducting eye of unknown, not necessarily paretic origin. The term "old trochlear palsy" may be erroneous since the hypertropia is not necessarily larger in downward gaze and a causative lesion can usually not be identified. We d...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1035299

    authors: Kommerell G,Mattheus S,Mühlendyck H

    更新日期:1996-08-01 00:00:00

  • [Clinical and fluorescein angiography findings in patients with retinal vein occlusion. A unicenter study of 211 patients].

    abstract::Between january 1986 and december 1989 we prospectively studied 211 patients with branch retinal vein occlusion (BRVO). Documented by fundus photography and fluorescein angiography clinical and angiographic findings were analysed. The age ranged from 28 to 83 with a mean of 63 years. 104 (48.8%) patients were male, 10...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1045901

    authors: Lang GE,Freissler K

    更新日期:1992-10-01 00:00:00

  • Intravitreal triamcinolone injection for unresponsive cystoid macular oedema in probable Behçet's disease as an additional therapy.

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    pub_type: 杂志文章

    doi:10.1055/s-2008-1027351

    authors: Oueghlani E,Pavésio CE

    更新日期:2008-05-01 00:00:00

  • [Observations on cataract incision dehiscence (author's transl)].

    abstract::24 patients with rupturing corneal incisions were observed within 6 years from 1971 until 1976. 19 patients had already had cataract extractions performed by us. This complication occurred in 0.5% of cases. All ruptures were investigated regarding the period of time after the cataract extraction, and possible precipit...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Bleckmann H

    更新日期:1977-05-01 00:00:00

  • [Are there genuine and pseudo-normal pressure glaucomas? Body position-dependent intraocular pressure values in normal pressure glaucoma].

    abstract:BACKGROUND:Elevation of intraocular pressure in the supine position has been previously described in literature. Aim of this study is to investigate the elevation of intraocular pressure in normal tension glaucoma and its effect on the morphology of the optic disc, visual field function and capillary blood flow of the ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1035128

    authors: Mardin CY,Jonas J,Michelson G,Jünemann A

    更新日期:1997-10-01 00:00:00

  • [Selective thrombophilia screening of young patients with retinal vein occlusion].

    abstract:BACKGROUND:The potential impact of coagulation abnormalities on retinal vascular occlusive diseases, individually and in combination with cardiovascular risk factors, remains unclear. PATIENTS AND METHODS:In a prospective case-control study a cohort of 74 young patients with central, hemicentral or branch retinal vein...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-0028-1109195

    authors: Kuhli-Hattenbach C,Scharrer I,Lüchtenberg M,Hattenbach LO

    更新日期:2009-09-01 00:00:00

  • [Silent sinus syndrome: an unusual cause of vertical diplopia].

    abstract:BACKGROUND:Causes of transient vertical diplopia include myasthenia, dysthyroid orbitopathy, multiple sclerosis, decompensation of a pre-existing state. PURPOSE:To describe an unusual cause of transient diplopia, silent sinus syndrome. METHODS:Clinical, radiological and pathology findings from a 55-year-old man with ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1034917

    authors: Durig J,Borruat FX,Jaques B

    更新日期:1998-05-01 00:00:00

  • [A new iridocorneal endothelial syndrome].

    abstract::Three iridocorneal endothelial syndromes are distinguished: essential progressive iris atrophy, iris nevus (Cogan-Reese) syndrome, and Chandler's syndrome. Obviously, there are patients in whom findings do not correspond fully to any one of the three syndromes; signs and symptoms which justify being considered as a ne...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1050446

    authors: Slezak H,Stur M,Strasser G

    更新日期:1987-06-01 00:00:00

  • Spasm of accommodation in a patient with increased intracranial pressure and pineal cyst.

    abstract:BACKGROUND:In the setting of a normal neurological examination, accommodation spasm is frequently attributed to a non-organic etiology. Occasionally, organic disorders are associated. In particular, central lesions involving the dorsal midbrain and quadrigeminal plate have been described with disorders of accommodation...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2005-857976

    authors: Kawasaki A,Borruat FX

    更新日期:2005-03-01 00:00:00

  • [Timolol in the treatment of glaucoma (author's transl)].

    abstract::Untolerated or insufficiently effective Therapy in 32 patients (63 eyes) with primary open-angle glaucoma was discontinued and substituted with Timolol, and all patients were followed up over a period of 60 weeks. Timolol was well tolerated in all cases without any local or systemic side effects. Either alone or in co...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1057171

    authors: Strasser G,Haddad R,Wohlzogen FX

    更新日期:1981-02-01 00:00:00

  • [New trends in tonometry].

    abstract:BACKGROUND:Though the knowledge about the risk of elevated intraocular pressure for pathogenesis for development and progress of glaucoma is more than 400 years old. It took another 300 years before by means of tonometry this elevation could be quantified. After discussion of the key words it is our aim to demonstrate ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-2006-927161

    authors: Draeger JA,Schwenteck T,Ruokonen PC

    更新日期:2006-10-01 00:00:00

  • Effect of Risk Alleles in CFH, C3, and VEGFA on the Response to Intravitreal Bevacizumab in Tunisian Patients with Neovascular Age-related Macular Degeneration.

    abstract::Purpose. The aim of this pharmacogenetic study was to evaluate the impact of high-risk alleles in factor H, factor C3 and vascular endothelial growth factor (VEGF) on the response to intravitreal bevacizumab in patients with neovascular age-related macular degeneration (AMD) in a Tunisian population. Methods. Ninety p...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-0041-111801

    authors: Habibi I,Kort F,Sfar I,Chebil A,Bouraoui R,Ben Abdallah T,Gorgi Y,El Matri L

    更新日期:2016-04-01 00:00:00

  • [ERG and EOG results in X-chromosomal vitreo-retinal degeneration (author transl)].

    abstract::ERG and EOG were performed in three male patients deriving from two no related families and who had vitreo-retinal degeneration including macula area. The EOG was below normal and ERG-potentials particularly b-waves reduced. The finding although of interest are not pathognomically significant. Therefore the diagnosis ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Denden A

    更新日期:1975-01-01 00:00:00

  • [Ciliary body metastasis as the first sign of small-cell bronchial carcinoma].

    abstract:BACKGROUND:About 3-10% of patients suffering from metastatic disease develop metastatic choroidal tumors. In this case report ocular symptoms were the first sign of a systemic malignancy. CASE REPORT:A 65-year old man complained of an increasing painful redness of his left eye. He showed a white mass with 10 mm in thi...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2000-10578

    authors: Stoffelns BM,Dick B

    更新日期:2000-05-01 00:00:00

  • [Factors influencing applanation tonometry - a practical approach].

    abstract::Applanation tonometry has been the gold standard in clinical ophthalmology for more than fifty years. The most popular factor is central corneal thickness that is now routinely considered in glaucoma management. However, other individual features of the cornea can also play a key role for the interpretation of the app...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-0029-1246037

    authors: Rosentreter A,Neuburger M,Jordan JF,Schild AM,Dietlein TS

    更新日期:2011-02-01 00:00:00

  • [Type I lattice corneal dystrophy. Clinical and molecular genetic study of a large family].

    abstract:BACKGROUND:Lattice corneal dystrophy type I is one of the frequent forms of stromal dystrophies following autosomal dominant inheritance. The beta-IG-h3 gene encoding keratoepithelin on the long arm of chromosome 5 has recently been described as disease gene for lattice corneal dystrophy type I as well as for three oth...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1034852

    authors: Meins M,Kohlhaas M,Richard G,Gal A

    更新日期:1998-03-01 00:00:00

  • [Ab externo sclerostomy with the Er:YAG laser: report of outcome after 2 years].

    abstract:OBJECT:Results over a period of 24 months of performing the Er:YAG laser ab externo sclerostomy. MATERIAL AND METHODS:The procedure was performed 81 times (chronic glaucoma with open angle (n = 55) and narrow angle (n = 15), 6 secondary glaucoma, 4 pigment glaucoma, 1 normal pressure glaucoma) in 74 eyes of 64 patient...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1035199

    authors: Kampmeier J,Klafke M,Hibst R,Wierschin S,Schütte E,Steiner R

    更新日期:1996-04-01 00:00:00

  • Strabismus Surgery of Consecutive Exotropia.

    abstract:PURPOSE:The purpose of this study was to determine the surgical outcome, dose-effect (DE), and degree of binocularity in patients undergoing surgery for consecutive exotropia following initial surgery of esotropia. PATIENTS/METHODS:Twenty-one patients were identified. We analyzed the mean angle of deviation pre- and p...

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    pub_type: 杂志文章

    doi:10.1055/a-1097-5653

    authors: Janeschitz-Kriegl L,Roulez F,Wipf MM,Palmowski-Wolfe A

    更新日期:2020-04-01 00:00:00

  • [Diminution of myopia following operation of macular hole-induced retinal detachment].

    abstract::This paper presents an assessment of the diminution of myopia in 25 eyes after surgery according to the technique of G. P. Theodossiadis for retinal detachment due to a macular hole. The procedure consists in the stretching and fixation of a silicone sponge at the posterior pole and dispenses entirely with either cryo...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1050806

    authors: Theodossiadis GP,Damanakis AG,Koutsandrea CN

    更新日期:1986-10-01 00:00:00