Abstract:
BACKGROUND:Elevation of intraocular pressure in the supine position has been previously described in literature. Aim of this study is to investigate the elevation of intraocular pressure in normal tension glaucoma and its effect on the morphology of the optic disc, visual field function and capillary blood flow of the retina and optic disc. PATIENTS AND METHODS:56 eyes of 28 preperimetric and advanced normal tension glaucoma patients were prospectively evaluated. Ten eyes of ten normal patients served as a control group for the measurements of the intraocular pressure. In the course of a 24-h pressure profile applanation tonometry was performed in the morning in a supine and three and ten minutes later in a sitting position with Draeger's and Goldmann's tonometers. Arterial blood pressure was measured at the same time. The optic disc's morphology was evaluated by stereo photographs and Laser Scanning Tomography. As a sensory test computer perimetry was used. Capillary blood flow was measured at defined areas of the retina and optic disc. An intraocular pressure above 21 mm Hg in the supine position was used as a criterium to define two groups of normal tension glaucoma patients. RESULTS:In the supine position a statistically significant elevation of intraocular pressure was observed in 24 normal tension glaucoma patients by 6.2 +/- 2.8 mm Hg up to 21.8 +/- 3 mm Hg. Diastolic blood pressure in the supine position (80 +/- 10.5 mm Hg) was significantly lower than in the sitting position (94 +/- 11 mm Hg, p = 0.021). 12 of 28 normal tension glaucoma patients showed an intraocular pressure lower than 22 mm Hg in the supine position. In these patients a tendency towards a higher incidence for the occurrence of optic disc haemorrhages and significantly higher values for blood flow (p < 0.0005) and volume (p < 0.005) in the retina and optic nerve head could be shown. In this group of normal pressure glaucoma patients a higher incidence of migraine and vasospastic complaints was reported in the patients' history. CONCLUSION:In this study some normal tension glaucoma patients showed intraocular pressures in the supine position higher than 21 mm Hg and a lower diastolic arterial pressure. The higher incidence of haemorrhages and higher values for flow and volume parameters of the optic disc in normal tension glaucoma patients with an intraocular pressure lower than 22 mm Hg implicate the existence of two entities: real and pseudo normal tension glaucomas.
journal_name
Klin Monbl Augenheilkdjournal_title
Klinische Monatsblatter fur Augenheilkundeauthors
Mardin CY,Jonas J,Michelson G,Jünemann Adoi
10.1055/s-2008-1035128subject
Has Abstractpub_date
1997-10-01 00:00:00pages
235-40issue
4eissn
0023-2165issn
1439-3999journal_volume
211pub_type
杂志文章abstract:OBJECT:Results over a period of 24 months of performing the Er:YAG laser ab externo sclerostomy. MATERIAL AND METHODS:The procedure was performed 81 times (chronic glaucoma with open angle (n = 55) and narrow angle (n = 15), 6 secondary glaucoma, 4 pigment glaucoma, 1 normal pressure glaucoma) in 74 eyes of 64 patient...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1035199
更新日期:1996-04-01 00:00:00
abstract::The 30-prism-test is a relatively quick and simple method for many-sided testing binocular behaviour in near distance in patients with reading difficulties and asthenopic symptoms, respecting well known and assumed causes of the disturbances. Therefore indications for treatment are given. ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1035556
更新日期:1994-05-01 00:00:00
abstract::Thirty-six patients with postoperative microstrabismus (24 of them without or with only a slight amblyopia, 12 with severe unilateral amblyopia) and three control groups (normal binocular, long-term monocular, and inexperienced monocular subjects) were tested by their ability to hit 14 vertical sticks set in varied po...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050933
更新日期:1985-05-01 00:00:00
abstract::In this paper 21 cases of branch vein thrombosis and 15 cases of central retinal vein thrombosis treated by argon laser photocoagulation are compared with an untreated control group. The visual prognosis after photocoagulation was no better in the treated group than in the control group. After central retinal vein occ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1057347
更新日期:1981-12-01 00:00:00
abstract::A very rare combination of congenital malformations of the eyelids and eyes in a 6-month-old boy is reported. The main symptoms are a bilateral microblepharon associated with ectropion and bilateral aphakic microphthalmus. The pathogenesis of these changes is discussed. ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1057334
更新日期:1981-11-01 00:00:00
abstract::A case of Zinsser-Engman-Cole syndrome (Dyskeratosis congenita) with severe fundus changes is reported. ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1975-05-01 00:00:00
abstract::Between january 1986 and december 1989 we prospectively studied 211 patients with branch retinal vein occlusion (BRVO). Documented by fundus photography and fluorescein angiography clinical and angiographic findings were analysed. The age ranged from 28 to 83 with a mean of 63 years. 104 (48.8%) patients were male, 10...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1045901
更新日期:1992-10-01 00:00:00
abstract:BACKGROUND:Pseudoexfoliation syndrome is a frequent cause of secondary open-angle glaucoma due to deposition and in situ-production of abnormal extracellular matrix proteins in the trabecular meshwork. Glaucomas itself are a known risk factor for retinal vein thrombosis. In this retrospective study the prevalence of ps...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1035088
更新日期:1997-07-01 00:00:00
abstract:BACKGROUND:Affections of the lacrimal drainage system are often seen by ophthalmologists. Inspection, palpation, diagnostic rinsing and sounding can distinguish anatomical stops before or after tear sac. For final diagnostics however more apparative examinations are necessary. The ultrasonic examination with contrast m...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1035009
更新日期:1997-01-01 00:00:00
abstract::In unilateral stenosis of the internal carotid artery tonography shows the differences in amplitudes in a comparison of the two sides; in bilateral stenosis it shows markedly reduced amplitudes with an intermittent absence of the pulse amplitudes. When extrasystoles occur there are characteristic reductions in the amp...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1057270
更新日期:1981-08-01 00:00:00
abstract:OBJECTIVE:To study the learning risk of a new surgical technique, the deep sclerectomy (DS), which may be complicated with a perforation of the trabeculodescemetic membrane. To do so, we compared the results and the complications of patients who underwent DS transformed in trabeculectomy (DSt) and those of patients who...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1035050
更新日期:1997-05-01 00:00:00
abstract::A new procedure of piezometry of the orbit with electronic recording of the data obtained is being described. The advantages offered by this method are the unprecedented possibility of conducting long-term tests, the high accuracy of the measurements (0.1 mm), and transpalpebral measuring involving a minimum of inconv...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1975-10-01 00:00:00
abstract::Using the laser flare-cell meter (LFMC), we have previously determined the intensity and pattern of post-ALT ocular inflammation. Inflammation peak occurs 48 hours after ALT and clinically relevant inflammation is seen in 100% of pigmentary glaucomas (PIG), 75% of pseudoexfoliative glaucomas (PEXG) but only in 25% of ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1055/s-2008-1045765
更新日期:1992-05-01 00:00:00
abstract::After a brief statistical survey the anotomic basis is explained in a broad outline. In the description of a case with bilateral paralysis of the abducens nerve, the suffering of the patient in his working life is examined and the phenomenon of inacurrate depth projection, of "pointing past", is discussed. As a result...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1976-02-01 00:00:00
abstract::Using the CANON CG 6 60 Z wide-angle fundus camera, fluorescein angiographic examinations of the fundus periphery were performed on 90 diabetic patients presenting with exudative diabetic maculopathy. The peripheral angiogram demonstrates that perimacular hyperpermeability - the main cause of diabetic maculopathy - is...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050901
更新日期:1985-03-01 00:00:00
abstract::Gene therapy raised euphoric expectations in the past that have yet to be met and have even been lowered due to the absence of concrete clinical successes and the occurrence of some tragic incidents. In spite of the great future potential of gene therapy, numerous pilot studies in this field will probably be discontin...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-2003-44610
更新日期:2003-11-01 00:00:00
abstract::Biologic disease modifying antirheumatic drugs (bDMARDs) can be highly efficient in the treatment of various non-infectious uveitis entities. Currently, the TNF-α-inhibitor Adalimumab is the only in-label therapeutic option, whereas, all other bDMARDs need to be given as an off-label therapy. bDMARDs are indicated in ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/a-0577-8006
更新日期:2018-05-01 00:00:00
abstract::In the ERG the b-wave and the oscillatory potentials are reduced or nonrecordable in ischemic retinopathy. The photopic b-wave appeared to be more sensitive than the scotopic b-wave. In the EOG the slow oscillation is reduced. These clinical observations are in accordance with the results of experimental studies in rh...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1979-03-01 00:00:00
abstract::Congenital, bilaterally symmetrical dislocation of the lens within the posterior chamber is referred to as lens ectopia. The behavior of the anterior hyaloid membrane in congenital lens ectopia has not been considered hitherto. The anterior hyaloid membrane in the aphakic area of the pupil is intact or ruptured and th...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050519
更新日期:1987-11-01 00:00:00
abstract::In a series of 6000 cases of pseudophakia following extracapsular cataract extraction and implantation of Simcoe-type posterior chamber lenses, observed for a minimum of 20 months, the incidence of retinal detachment was 21 cases (0.33%). Significant risk factors include male sex (18/21, 82%), high myopia (axial lengt...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050061
更新日期:1988-01-01 00:00:00
abstract::Radioactively labelled microspheres (size 15 micron) were used to determine the regional blood flow in cats before and 15, 30 and 45 minutes after unilateral drug administration. In four experimental groups, each consisting of five animals, two drops of the drug were administered into the conjunctival sac. The blood f...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1978-03-01 00:00:00
abstract:PURPOSE:The aim of this study was to compare the different calculation methods in large patient collectives, including eyes with extreme axial lengths. METHOD AND MATERIAL:The prediction errors of the Haigis, SRK/T, Hoffer-Q and Holladay formulae and of the OKULIX ray-tracing are compared in 2888 normal eyes implanted...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1027966
更新日期:2009-02-01 00:00:00
abstract::After a discussion of the pathomechanism of skull trauma by a blow leading to chiasmal lesion, frontobasal injuries of the skull are considered; it is shown that typical defects of the visual field resulting from chiasmal damage can be revealed not only in cases of serious industrial or traffic accidents with brain co...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1976-11-01 00:00:00
abstract::This work is a survey of 82 cases of keratoconus which have been followed up for 1 to 12 years. Among them only 66 were fitted with contact lenses. The contra-indications for them are: 1. a better visual acuity with spectacles than with contact lenses, 2. advanced cases (4th degree of Amsler) whose fitting is impossib...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract:BACKGROUND:Using biomicroscopy the evidence of deposits of silicone oil in the anterior segment after vitrectomy is limited. We examined the anterior segment by high resolution ultrasound to verify the possibility to identify silicone oil. MATERIALS AND METHODS:Ten patients treated by vitrectomy with instillation of s...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2002-36327
更新日期:2002-11-01 00:00:00
abstract::From 126 patients with ocular hypertension and/or primary open-angle glaucoma, those (n = 18) who had an untreated intraocular pressure of at least 25 mm Hg or a cup/disk ratio of at least 0.8 were selected for this study. The course of the disease was followed by means of photos of the disk and visual field examinati...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050763
更新日期:1986-08-01 00:00:00
abstract::A large variety of diseases may cause a subretinal neovascularization originating from choroidal vessels. Four cases of parapillary choroidal neovascularisation are described, including neovascularization caused by senile and myopic degeneration, by drusen of the optic nerve head, and by angioid streaks. Obliteration ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050277
更新日期:1988-10-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate tumour regression in a large series of choroidal melanomas, which were treated with three different eye-sparing treatment modalities. PATIENTS AND METHODS:Retrospective review of the treatment results in all eyes with malignant choroidal melanoma, which were treated in the...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0029-1245224
更新日期:2010-04-01 00:00:00
abstract::Purpose. The aim of this pharmacogenetic study was to evaluate the impact of high-risk alleles in factor H, factor C3 and vascular endothelial growth factor (VEGF) on the response to intravitreal bevacizumab in patients with neovascular age-related macular degeneration (AMD) in a Tunisian population. Methods. Ninety p...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0041-111801
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:The aim of this study is to report the feasibility of one to two weeks delayed reconstruction after eyelid tumor excision. PATIENTS AND METHODS:A retrospective case-series study was designed. Fourteen consecutive outpatients referred to a tertiary referral eye center for eyelid tumor management were enrolle...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0031-1299208
更新日期:2012-04-01 00:00:00