Detection of novel sequences related to african Swine Fever virus in human serum and sewage.

Abstract:

:The family Asfarviridae contains only a single virus species, African swine fever virus (ASFV). ASFV is a viral agent with significant economic impact due to its devastating effects on populations of domesticated pigs during outbreaks but has not been reported to infect humans. We report here the discovery of novel viral sequences in human serum and sewage which are clearly related to the asfarvirus family but highly divergent from ASFV. Detection of these sequences suggests that greater genetic diversity may exist among asfarviruses than previously thought and raises the possibility that human infection by asfarviruses may occur.

journal_name

J Virol

journal_title

Journal of virology

authors

Loh J,Zhao G,Presti RM,Holtz LR,Finkbeiner SR,Droit L,Villasana Z,Todd C,Pipas JM,Calgua B,Girones R,Wang D,Virgin HW

doi

10.1128/JVI.00638-09

subject

Has Abstract

pub_date

2009-12-01 00:00:00

pages

13019-25

issue

24

eissn

0022-538X

issn

1098-5514

pii

JVI.00638-09

journal_volume

83

pub_type

杂志文章
  • Evidence that a capped oligoribonucleotide is the primer for duck hepatitis B virus plus-strand DNA synthesis.

    abstract::The plus strand of virion DNA of duck hepatitis B virus possessed, at its 5' terminus, a capped oligoribonucleotide 18 to 19 bases in length. This oligoribonucleotide had a unique 5' end, the heterogeneity in length reflecting two distinct junctions with plus-strand DNA that were 1 base apart. The sequence of the RNA ...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.57.1.229-236.1986

    authors: Lien JM,Aldrich CE,Mason WS

    更新日期:1986-01-01 00:00:00

  • Inhibition of Histone Deacetylase Activity Aggravates Coxsackievirus B3-Induced Myocarditis by Promoting Viral Replication and Myocardial Apoptosis.

    abstract:UNLABELLED:Viral myocarditis, which is most prevalently caused by coxsackievirus B3 (CVB3), is a serious clinical condition characterized by excessive myocardial inflammation. Recent studies suggest that regulation of protein acetylation levels by inhibiting histone deacetylase (HDAC) activity modulates inflammatory re...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.01028-15

    authors: Zhou L,He X,Gao B,Xiong S

    更新日期:2015-10-01 00:00:00

  • Selection of reversions and suppressors of a mutation in the CBF binding site of a lymphomagenic retrovirus.

    abstract::The retrovirus SL3 induces T-cell lymphomas in mice. The transcriptional enhancer in the long terminal repeat (LTR) of SL3 contains two 72-bp repeats. Each repeat contains a binding site for the transcription factor CBF (also called AML1). The CBF binding sites are called core elements. SAA is a mutant that is identic...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.73.9.7599-7606.1999

    authors: Martiney MJ,Rulli K,Beaty R,Levy LS,Lenz J

    更新日期:1999-09-01 00:00:00

  • Roles of VP4 and NSP1 in determining the distinctive replication capacities of simian rotavirus RRV and bovine rotavirus UK in the mouse biliary tract.

    abstract::Rotavirus replication and virulence are strongly influenced by virus strain and host species. The rotavirus proteins VP3, VP4, VP7, NSP1, and NSP4 have all been implicated in strain and species restriction of replication; however, the mechanisms have not been fully determined. Simian (RRV) and bovine (UK) rotaviruses ...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.02408-10

    authors: Feng N,Sen A,Wolf M,Vo P,Hoshino Y,Greenberg HB

    更新日期:2011-03-01 00:00:00

  • Mechanisms of human papillomavirus E2-mediated repression of viral oncogene expression and cervical cancer cell growth inhibition.

    abstract::The papillomavirus E2 gene product plays a pivotal role in viral replication. E2 has multiple functions, including (i) transcriptional activation and repression of viral promoters and (ii) the enhancement of viral DNA replication. It was previously reported that E2 suppressed the growth of papillomavirus-positive cerv...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/jvi.74.8.3752-3760.2000

    authors: Nishimura A,Ono T,Ishimoto A,Dowhanick JJ,Frizzell MA,Howley PM,Sakai H

    更新日期:2000-04-01 00:00:00

  • Two independent regions of simian virus 40 T antigen increase CBP/p300 levels, alter patterns of cellular histone acetylation, and immortalize primary cells.

    abstract::Simian virus 40 (SV40) large T antigen (SVT) interferes with normal cell regulation and thus has been used to identify cellular components controlling proliferation and homeostasis. We have previously shown that SVT-mediated transformation requires interaction with the histone acetyltransferases (HATs) CBP/p300 and no...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.02658-13

    authors: Sáenz Robles MT,Shivalila C,Wano J,Sorrells S,Roos A,Pipas JM

    更新日期:2013-12-01 00:00:00

  • Structurally similar woodchuck and human hepadnavirus core proteins have distinctly different temperature dependences of assembly.

    abstract:UNLABELLED:Woodchuck hepatitis virus (WHV), a close relative of human hepatitis B virus (HBV), has been a key model for disease progression and clinical studies. Sequences of the assembly domain of WHV and HBV core proteins (wCp149 and hCp149, respectively) have 65% identity, suggesting similar assembly behaviors. We r...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.01840-14

    authors: Kukreja AA,Wang JC,Pierson E,Keifer DZ,Selzer L,Tan Z,Dragnea B,Jarrold MF,Zlotnick A

    更新日期:2014-12-01 00:00:00

  • The large delta antigen of hepatitis delta virus potently inhibits genomic but not antigenomic RNA synthesis: a mechanism enabling initiation of viral replication.

    abstract::Hepatitis delta virus (HDV) contains two types of hepatitis delta antigens (HDAg) in the virion. The small form (S-HDAg) is required for HDV RNA replication, whereas the large form (L-HDAg) potently inhibits it by a dominant-negative inhibitory mechanism. The sequential appearance of these two forms in the infected ce...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/jvi.74.16.7375-7380.2000

    authors: Modahl LE,Lai MM

    更新日期:2000-08-01 00:00:00

  • The L-coding region of the DA strain of Theiler's murine encephalomyelitis virus causes dysfunction and death of myelin-synthesizing cells.

    abstract::The DA strain and other members of the TO subgroup of Theiler's murine encephalomyelitis virus (TMEV) induce an early transient subclinical neuronal disease followed by a chronic progressive inflammatory demyelination, with persistence of the virus in the central nervous system (CNS) for the life of the mouse. Althoug...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.00178-11

    authors: Ghadge GD,Wollmann R,Baida G,Traka M,Roos RP

    更新日期:2011-09-01 00:00:00

  • Effect of vesicular stomatitis virus infection on the histocompatibility antigen of L cells.

    abstract::When mouse L cells are infected for 22 hr with vesicular stomatitis virus (VSV), a ribonucleic acid-containing enveloped virus, greater than 70% of the major histocompatibility antigen (H-2), is no longer detectable by the method of inhibition of immune cytolysis. Infected cells prelabeled with (14)C-glucosamine also ...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.10.4.578-585.1972

    authors: Hecht TT,Summers DF

    更新日期:1972-10-01 00:00:00

  • A genetic system for rhesus monkey rhadinovirus: use of recombinant virus to quantitate antibody-mediated neutralization.

    abstract::Rhesus monkey rhadinovirus (RRV), a simian gamma-2 herpesvirus closely related to the Kaposi sarcoma-associated herpesvirus, replicates lytically in cultured rhesus monkey fibroblasts and establishes persistence in B cells. Overlapping cosmid clones were generated that encompass the entire 130-kilobase-pair genome of ...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.80.3.1549-1562.2006

    authors: Bilello JP,Morgan JS,Damania B,Lang SM,Desrosiers RC

    更新日期:2006-02-01 00:00:00

  • Virion Structure of Iflavirus Slow Bee Paralysis Virus at 2.6-Angstrom Resolution.

    abstract:UNLABELLED:The western honeybee (Apis mellifera) is the most important commercial insect pollinator. However, bees are under pressure from habitat loss, environmental stress, and pathogens, including viruses that can cause lethal epidemics. Slow bee paralysis virus (SBPV) belongs to the Iflaviridae family of nonenvelop...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.00680-16

    authors: Kalynych S,Přidal A,Pálková L,Levdansky Y,de Miranda JR,Plevka P

    更新日期:2016-07-27 00:00:00

  • Human T-cell leukemia virus type 1 Tax transactivates the human proliferating cell nuclear antigen promoter.

    abstract::The human T-cell leukemia virus type 1 (HTLV-1) transforming protein, Tax, is a potent transactivator of both viral and cellular gene expression. The ability of Tax to transform cells is believed to depend on its transactivation of cellular-growth-regulatory genes. Expression of proliferating cell nuclear antigen (PCN...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.71.2.1181-1190.1997

    authors: Ressler S,Morris GF,Marriott SJ

    更新日期:1997-02-01 00:00:00

  • Human immunodeficiency virus type 1 Tat regulates endothelial cell actin cytoskeletal dynamics through PAK1 activation and oxidant production.

    abstract::Human immunodeficiency virus type 1 Tat exerts prominent angiogenic effects which may lead to a variety of vasculopathic conditions in AIDS patients. Because endothelial cells undergo prominent cytoskeletal rearrangement during angiogenesis, we investigated the specific effects of Tat on the endothelial cell actin cyt...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/jvi.78.2.779-789.2004

    authors: Wu RF,Gu Y,Xu YC,Mitola S,Bussolino F,Terada LS

    更新日期:2004-01-01 00:00:00

  • Dengue type 4 virus mutants containing deletions in the 3' noncoding region of the RNA genome: analysis of growth restriction in cell culture and altered viremia pattern and immunogenicity in rhesus monkeys.

    abstract::The dengue type 4 virus (DEN4) genome contains a 384-nucleotide (nt) 3' noncoding sequence in which the last 81 nt, predicted to form a secondary structure, are thought to be essential for virus replication. Immediately upstream of the secondary structure, short RNA sequences that are conserved among mosquito-borne fl...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.70.6.3930-3937.1996

    authors: Men R,Bray M,Clark D,Chanock RM,Lai CJ

    更新日期:1996-06-01 00:00:00

  • Twin studies demonstrate a host cell genetic effect on productive human immunodeficiency virus infection of human monocytes and macrophages in vitro.

    abstract::Biological and genetic variability is a prominent feature of human immunodeficiency virus (HIV) strains, especially in tropism, syncytium formation, and replicative capacity. To determine whether there were variable host cell effects on HIV replication in monocytes, three different strains of low-passage-number monocy...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.70.11.7792-7803.1996

    authors: Chang J,Naif HM,Li S,Sullivan JS,Randle CM,Cunningham AL

    更新日期:1996-11-01 00:00:00

  • Distal leucines are key functional determinants of Alix-binding simian immunodeficiency virus SIV(smE543) and SIV(mac239) type 3 L domains.

    abstract::In addition to PTAP L domains, primate lentiviruses carry Alix-binding motifs that include the recently described type 3 SREKPYKEVTEDLLHLNSLF sequence. We examined the requirements for the type 3 sequence motif in simian immunodeficiency virus SIV(smE543) and identified the (499)LNSLF(503) sequence as a key functional...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.05284-11

    authors: Bello NF,Wu F,Sette P,Dussupt V,Hirsch VM,Bouamr F

    更新日期:2011-11-01 00:00:00

  • Multi-PDZ domain protein MUPP1 is a cellular target for both adenovirus E4-ORF1 and high-risk papillomavirus type 18 E6 oncoproteins.

    abstract::A general theme that has emerged from studies of DNA tumor viruses is that otherwise unrelated oncoproteins encoded by these viruses often target the same important cellular factors. Major oncogenic determinants for human adenovirus type 9 (Ad9) and high-risk human papillomaviruses (HPV) are the E4-ORF1 and E6 oncopro...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/jvi.74.20.9680-9693.2000

    authors: Lee SS,Glaunsinger B,Mantovani F,Banks L,Javier RT

    更新日期:2000-10-01 00:00:00

  • Size of genetic bottlenecks leading to virus fitness loss is determined by mean initial population fitness.

    abstract::Genetic bottlenecks are important events in the genetic diversification of organisms and colonization of new ecological niches. Repeated bottlenecking of RNA viruses often leads to fitness losses due to the operation of Muller's ratchet. Herein we use vesicular stomatitis virus to determine the transmission population...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.69.5.2869-2872.1995

    authors: Novella IS,Elena SF,Moya A,Domingo E,Holland JJ

    更新日期:1995-05-01 00:00:00

  • Analysis of viral and cellular factors influencing herpesvirus-induced nuclear envelope breakdown.

    abstract::Herpesvirus nucleocapsids are translocated from their assembly site in the nucleus to the cytosol by acquisition of a primary envelope at the inner nuclear membrane which subsequently fuses with the outer nuclear membrane. This transport through the nuclear envelope requires homologs of the conserved herpesviral pUL31...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.00068-12

    authors: Grimm KS,Klupp BG,Granzow H,Müller FM,Fuchs W,Mettenleiter TC

    更新日期:2012-06-01 00:00:00

  • ATPgammaS disrupts human immunodeficiency virus type 1 virion core integrity.

    abstract::Heat shock protein 70 (Hsp70) is incorporated within the membrane of primate lentiviral virions. Here we demonstrate that Hsp70 is also incorporated into oncoretroviral virions and that it remains associated with membrane-stripped human immunodeficiency virus type 1 (HIV-1) virion cores. To determine if Hsp70 promotes...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.79.9.5557-5567.2005

    authors: Gurer C,Höglund A,Höglund S,Luban J

    更新日期:2005-05-01 00:00:00

  • LANA and hnRNP A1 Regulate the Translation of LANA mRNA through G-Quadruplexes.

    abstract::During the latent phase, Kaposi's sarcoma-associated herpes virus (KSHV) maintains itself inside the host by escaping the host immune surveillance mechanism through restricted protein expression. Latency-associated nuclear antigen (LANA), the most abundantly expressed protein, is essential for viral persistence, as it...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.01508-19

    authors: Dabral P,Babu J,Zareie A,Verma SC

    更新日期:2020-01-17 00:00:00

  • Human papillomavirus type 16 E5 protein induces expression of beta interferon through interferon regulatory factor 1 in human keratinocytes.

    abstract::Crucial steps in high-risk human papillomavirus (HR-HPV)-related carcinogenesis are the integration of HR-HPV into the host genome and loss of viral episomes. The mechanisms that promote cervical neoplastic progression are, however, not clearly understood. During HR-HPV infection, the HPV E5 protein is expressed in pr...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.02114-10

    authors: Muto V,Stellacci E,Lamberti AG,Perrotti E,Carrabba A,Matera G,Sgarbanti M,Battistini A,Liberto MC,Focà A

    更新日期:2011-05-01 00:00:00

  • Clinical Control of HIV-1 by Cytotoxic T Cells Specific for Multiple Conserved Epitopes.

    abstract:UNLABELLED:Identification and characterization of CD8(+) T cells effectively controlling HIV-1 variants are necessary for the development of AIDS vaccines and for studies of AIDS pathogenesis, although such CD8(+) T cells have been only partially identified. In this study, we sought to identify CD8(+) T cells controlli...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.00020-15

    authors: Murakoshi H,Akahoshi T,Koyanagi M,Chikata T,Naruto T,Maruyama R,Tamura Y,Ishizuka N,Gatanaga H,Oka S,Takiguchi M

    更新日期:2015-05-01 00:00:00

  • Foot-and-mouth disease virus, but not bovine enterovirus, targets the host cell cytoskeleton via the nonstructural protein 3Cpro.

    abstract::Foot-and-mouth disease virus (FMDV), a member of the Picornaviridae, is a pathogen of cloven-hoofed animals and causes a disease of major economic importance. Picornavirus-infected cells show changes in cell morphology and rearrangement of cytoplasmic membranes, which are a consequence of virus replication. We show he...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.00907-08

    authors: Armer H,Moffat K,Wileman T,Belsham GJ,Jackson T,Duprex WP,Ryan M,Monaghan P

    更新日期:2008-11-01 00:00:00

  • SERINC5 Inhibits HIV-1 Infectivity by Altering the Conformation of gp120 on HIV-1 Particles.

    abstract::SERINC5 is a 10-transmembrane-domain cellular protein that is incorporated into budding HIV-1 particles and reduces HIV-1 infectivity by inhibiting virus-cell fusion. HIV-1 susceptibility to SERINC5 is determined by sequences in the viral Env glycoprotein gp120, and the antiviral effect of SERINC5 is counteracted by t...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.00594-20

    authors: Featherstone A,Aiken C

    更新日期:2020-09-29 00:00:00

  • Analysis of gag proteins from mouse mammary tumor virus.

    abstract::Structural proteins designated p10gag, p21gag, p8gag, p3gag, p27gag, and p14gag from the C3H strain of mouse mammary tumor virus (MMTV) were purified by reversed-phase high-pressure liquid chromatography. The N- and C-terminal amino acid sequences and amino acid composition of each protein were determined and compared...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.63.6.2543-2549.1989

    authors: Hizi A,Henderson LE,Copeland TD,Sowder RC,Krutzsch HC,Oroszlan S

    更新日期:1989-06-01 00:00:00

  • Parvovirus Capsid Structures Required for Infection: Mutations Controlling Receptor Recognition and Protease Cleavages.

    abstract::Parvovirus capsids are small but complex molecular machines responsible for undertaking many of the steps of cell infection, genome packing, and cell-to-cell as well as host-to-host transfer. The details of parvovirus infection of cells are still not fully understood, but the processes must involve small changes in th...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.01871-16

    authors: Callaway HM,Feng KH,Lee DW,Allison AB,Pinard M,McKenna R,Agbandje-McKenna M,Hafenstein S,Parrish CR

    更新日期:2017-01-03 00:00:00

  • Interleukin-15 and natural killer and NKT cells play a critical role in innate protection against genital herpes simplex virus type 2 infection.

    abstract::Interleukin-15 (IL-15), natural killer (NK) cells, and NK T (NKT) cells, components of the innate immune system, are known to contribute to defense against pathogens, including viruses. Here we report that IL-15(-/-) (NK(-) and NKT(-/+)) mice and RAG-2(-/-)/gamma(c)(-/-) (NK(-) and NKT(-)) mice that lack all lymphoid ...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/jvi.77.18.10168-10171.2003

    authors: Ashkar AA,Rosenthal KL

    更新日期:2003-09-01 00:00:00

  • Three arginine residues within the RGG box are crucial for ICP27 binding to herpes simplex virus 1 GC-rich sequences and for efficient viral RNA export.

    abstract::ICP27 is a multifunctional protein that is required for herpes simplex virus 1 mRNA export. ICP27 interacts with the mRNA export receptor TAP/NXF1 and binds RNA through an RGG box motif. Unlike other RGG box proteins, ICP27 does not bind G-quartet structures but instead binds GC-rich sequences that are flexible in str...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.00509-10

    authors: Corbin-Lickfett KA,Souki SK,Cocco MJ,Sandri-Goldin RM

    更新日期:2010-07-01 00:00:00