Thalamohippocampal atrophy in focal epilepsy of unknown cause at the time of diagnosis.

abstract：BACKGROUND:Idiopathic inflammatory demyelinating disorders (IIDD) affect the central nervous system. In classical multiple sclerosis (CMS), brain, optic nerves [optic neuritis (ON)] and spinal cord [acute transverse myelitis (ATM)] are affected. In neuromyelitis optica (NMO), optic nerves and spinal cord are predominan...

journal_title：European journal of neurology

authors： Chan KH,Ramsden DB,Yu YL,Kwok KH,Chu AC,Ho PW,Kwan JS,Lee R,Lim E,Kung MH,Ho SL

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Hereditary sensory and autonomic neuropathies (HSANs) are a group of clinically and genetically heterogeneous neurological disorders characterized by sensory dysfunctions. Here, 21 affected Chinese families are reported, including 19 with congenital insensitivity to pain with anhidrosis (CIPA; na...

journal_title：European journal of neurology

authors： Zhao F,Mao B,Geng X,Ren X,Wang Y,Guan Y,Li S,Li L,Zhang S,You Y,Cao Y,Yang T,Zhao X

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Studies investigating the association between 25-hydroxyvitamin D [25(OH)D] and cognition in the very old (85+) are lacking. METHODS:Cross-sectional (baseline) and prospective data (up to 3 years follow-up) from 775 participants in the Newcastle 85+ Study were analysed for global (measured by th...

journal_title：European journal of neurology

authors： Granic A,Hill TR,Kirkwood TB,Davies K,Collerton J,Martin-Ruiz C,von Zglinicki T,Saxby BK,Wesnes KA,Collerton D,Mathers JC,Jagger C

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Lower urinary tract symptoms (LUTS) including frequent urination, nocturia and urge urinary incontinence negatively impact quality of life. This project aimed at characterizing the prevalence and severity of urinary incontinence in multiple sclerosis (MS) patients and its association with demogra...

journal_title：European journal of neurology

authors： Zecca C,Riccitelli GC,Disanto G,Singh A,Digesu GA,Panicari L,Puccini F,Mattioli M,Tubaro A,Gobbi C

更新日期：2016-07-01 00:00:00

abstract：:Management of children with cerebral palsy (CP) is the focus of considerable resources in many countries, so that evaluation of the efficacy for new and established treatments is imperative. Botulinum toxin type A (BTX-A) is a relatively new method of spasticity management in children with cerebral palsy. It has been ...

journal_title：European journal of neurology

authors： Boyd RN,Hays RM

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Paraprotein-associated neuropathies have heterogeneous clinical, neurophysiological, neuropathological and haematological features. Objectives. To prepare evidence-based and consensus guidelines on the clinical management of patients with both a demyelinating neuropathy and a paraprotein (paraproteinaemic de...

journal_title：European journal of neurology

authors： European Federation of Neurological Societies.,Peripheral Nerve Society.,Hadden RD,Nobile-Orazio E,Sommer C,Hahn A,Illa I,Morra E,Pollard J,Hughes RA,Bouche P,Cornblath D,Evers E,Koski CL,Léger JM,Van den Bergh P,van Door

更新日期：2006-08-01 00:00:00

abstract：:It is not well established whether seizures and epilepsy after an ischaemic stroke increase the disability of patients. Seventy-two patients with delayed seizures after a hemispheric infarct (37 with a single seizure and 35 with epilepsy) were included in the study. The modified Rankin scale was used to compare disabi...

journal_title：European journal of neurology

authors： De Reuck J,Claeys I,Martens S,Vanwalleghem P,Van Maele G,Phlypo R,Hallez H

更新日期：2006-04-01 00:00:00

abstract：:We evaluated the putative factors for the onset of Guillain-Barré syndrome (GBS) in Harbin, China by a case-control study based on the information from GBS patients identified from a population-based incidence survey, which is the first study of this kind in China. Sixty-nine GBS patients were identified during a 1-ye...

journal_title：European journal of neurology

authors： Cheng Q,Wang DS,Jiang GX,Han H,Zhang Y,Wang WZ,Fredrikson S

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Multiple mitochondrial DNA (mtDNA) deletions usually have a mendelian inheritance secondary to mutation in nuclear genes. One of these is the Twinkle gene whose mutation is responsible for autosomal dominant progressive external ophthalmoplegia (PEO). The number of reported cases with mainly myopathic sympto...

journal_title：European journal of neurology

authors： Martin-Negrier ML,Sole G,Jardel C,Vital C,Ferrer X,Vital A

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The prognostic value of serum neurofilament light chain (sNfL), a biomarker of neurodegeneration, compared to other prognostic factors of amyotrophic lateral sclerosis (ALS) at the time of diagnosis, remains unclear. METHODS:Sera from ALS patients were prospectively collected at the first diagno...

journal_title：European journal of neurology

authors： Thouvenot E,Demattei C,Lehmann S,Maceski-Maleska A,Hirtz C,Juntas-Morales R,Pageot N,Esselin F,Alphandéry S,Vincent T,Camu W

更新日期：2020-02-01 00:00:00

abstract：:The presence of white matter lesions (WML) is an important prognostic factor for the development of stroke. Plasma total homocysteine (tHcy), which increases with diabetes, has been flagged as a novel predictor for cerebrovascular events. We tested the hypothesis that the presence of WML correlates with tHcy and insul...

journal_title：European journal of neurology

authors： Shimomura T,Anan F,Umeno Y,Eshima N,Saikawa T,Yoshimatsu H,Fujiki M,Kobayashi H

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The deleterious effect of hyperthermia on intracerebral hemorrhage (ICH) has been studied. However, the results are not conclusive and new studies are needed to elucidate clinical factors that influence the poor outcome. The aim of this study was to identify the clinical factors (including ICH et...

journal_title：European journal of neurology

authors： Iglesias-Rey R,Rodríguez-Yáñez M,Arias S,Santamaría M,Rodríguez-Castro E,López-Dequidt I,Hervella P,Sobrino T,Campos F,Castillo J

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Prevalence rates of headache in multiple sclerosis (MS) patients varied widely in recent studies. This study aimed to investigate the 1 year prevalence of headache in MS compared with the general population. METHODS:Population-based case-control study in Germany. RESULTS:We included 491 patients with defin...

journal_title：European journal of neurology

authors： Putzki N,Pfriem A,Limmroth V,Yaldizli O,Tettenborn B,Diener HC,Katsarava Z

更新日期：2009-02-01 00:00:00

abstract：:We here present the case of a patient with a sleep disturbance attributed to the exploding head syndrome, recently redefined as 'episodic cranial sensory shock'. The patient, who suffered with concomitant migraine, was treated for headache prevention with daily single-pulse transcranial magnetic stimulation. Following...

journal_title：European journal of neurology

authors： Puledda F,Moreno-Ajona D,Goadsby PJ

更新日期：2021-01-18 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of this study was to analyse the long-term impact of Guillain-Barré syndrome (GBS) on quality of life, and the relationship between clinical variables at disease onset and symptoms at follow-up to general health status. METHODS:Forty-two GBS patients were examined at median 6 years a...

journal_title：European journal of neurology

authors： Rudolph T,Larsen JP,Farbu E

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To evaluate the association between having non-thymoma myasthenia and the risk of extra-thymic cancer in a population-based setting. METHODS:A nationwide case-control study was conducted in Denmark based on medical registries. The study included all cases with a first time diagnosis of cancer du...

journal_title：European journal of neurology

authors： Pedersen EG,Pottegård A,Hallas J,Friis S,Hansen K,Jensen PE,Gaist D

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In contrast to anterior circulation stroke (ACS), there is no evidence from randomized trials that mechanical thrombectomy (MT) with modern stent retrievers or thromboaspiration is safe and effective in posterior circulation stroke (PCS). METHODS:The present analysis was based on the prospective...

journal_title：European journal of neurology

authors： Weber R,Minnerup J,Nordmeyer H,Eyding J,Krogias C,Hadisurya J,Berger K,REVASK investigators.

更新日期：2019-02-01 00:00:00

abstract：:Although the value of magnetic resonance imaging (MRI) for diagnosis/differential diagnosis of patients with clinically isolated syndromes suggestive of multiple sclerosis (MS) is widely accepted, adoption of MRI into clinical practice to monitor disease evolution remains a work in progress. However, an accumulating b...

journal_title：European journal of neurology

authors： Oreja-Guevara C,ParadigMS Group.

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The diagnosis of cytomegalovirus encephalitis (CMV-E) in AIDS patients is challenging as other illnesses may obscure the symptoms. Here, we characterize the clinical symptoms of CMV-E and link them to post-mortem findings. Patients and methods In 254 homosexual men with AIDS, followed from HIV di...

journal_title：European journal of neurology

authors： Pirskanen-Matell R,Grützmeier S,Nennesmo I,Sandström E,Ehrnst A

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Behçet's disease (BD) is a multisystemic, recurrent, inflammatory disorder. Neurological involvement is well-known but cerebral vasculitis and ischaemic stroke are unusual. CASE DESCRIPTION:A 43-year-old male patient presented with acute left hemiparesis, he had recurrent oral aphthae and scrotal ulcerati...

journal_title：European journal of neurology

authors： Krespi Y,Akman-Demir G,Poyraz M,Tugcu B,Coban O,Tuncay R,Serdaroglu P,Bahar S

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Benign paroxysmal positional vertigo (BPPV) is a frequently encountered condition that can severely affect the quality of life. In this study, we aimed to assess the possible relations between serum uric acid (SUA) levels and BPPV. METHODS:Fifty patients with BPPV, and 40 age- and sex-matched co...

journal_title：European journal of neurology

authors： Celikbilek A,Gencer ZK,Saydam L,Zararsiz G,Tanik N,Ozkiris M

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Dimethyl fumarate (DMF) causes a mean lymphocyte count drop of approximately 30% in relapsing-remitting multiple sclerosis (RRMS) patients. The relationship between this reduction and DMF effectiveness is controversial. The objective was to investigate if the decrease in absolute lymphocyte count...

journal_title：European journal of neurology

authors： Tsantes E,Curti E,Ferraro D,Lugaresi A,Baldi E,Montepietra S,Immovilli P,Simone AM,Mancinelli L,Strumia S,Vitetta F,Foschi M,Ferri C,Ferrarini C,Sola P,Granella F

更新日期：2021-01-01 00:00:00

abstract：:We report a novel missense mutation of the Notch3 gene in a Japanese family with CADASIL. The Cys49Gly mutation in this family is located in exon 2 of the Notch3 gene. Most of the documented Notch3 gene mutations occur in exons 3 or 4. On the other hand, there are few reports around the world of mutations in exon 2 of...

journal_title：European journal of neurology

authors： Oki K,Nagata E,Ishiko A,Shimizu A,Tanaka K,Takahashi K,Tabira T,Katayama T,Suzuki N

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The relative frequency of the different autosomal dominant cerebellar ataxia (ADCA) varies widely amongst different geographic locations. Here we describe a series of 45 ADCA families from Portugal. METHODS:Patients with progressive cerebellar dysfunction of autosomal dominant transmission under...

journal_title：European journal of neurology

authors： Vale J,Bugalho P,Silveira I,Sequeiros J,Guimarães J,Coutinho P

更新日期：2010-01-01 00:00:00

abstract：AIM:To investigate the corticomotor projection to the upper limb in children with hemiplegic cerebral palsy (CP) and the changes that occur with botulinum toxin (BTX)-A. METHODS:The study design is a pilot prospective randomized trial. Twenty-two children with hemiplegic CP aged 7 years to 13 years 11 months were recr...

journal_title：European journal of neurology

authors： Redman TA,Gibson N,Finn JC,Bremner AP,Valentine J,Thickbroom GW

更新日期：2008-08-01 00:00:00

abstract：:In approximately 40% of the patients, Parkinson's disease (PD) is complicated by cognitive impairment. The objective of this study was to evaluate the impact of cognitive impairment on disease severity and motor function in idiopathic PD patients. Forty-one PD patients with cognitive impairment (PD-CI) (Mini-Mental St...

journal_title：European journal of neurology

authors： Papapetropoulos S,Ellul J,Polychronopoulos P,Chroni E

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Approximately 9000 people in the UK are affected by Huntington's disease (HD). People with HD require ongoing health and social care support. There is a knowledge gap about costs of health and social care use associated with HD in the UK. This paper estimates the economic cost in the UK. METHODS...

journal_title：European journal of neurology

authors： Jones C,Busse M,Quinn L,Dawes H,Drew C,Kelson M,Hood K,Rosser A,Edwards RT

更新日期：2016-10-01 00:00:00

abstract：:Cocaine abuse is a well known cause of cerebrovascular complications. An inflammatory vasculopathy hypothesis has been proposed, but the medical literature has only reported a few pathological confirmations. We report a case with a biopsy demonstrating cerebral inflammatory vascular changes that are associated with co...

journal_title：European journal of neurology

authors： Diez-Tejedor E,Frank A,Gutierrez M,Barreiro P

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Ataxia-telangiectasia (A-T) is a rare neurodegenerative disease, due to A-T mutated (ATM) gene mutations, which typically presents with signs of progressive neurological dysfunction, cerebellar ataxia and uncoordinated movements. A-T severely affects patients' quality of life. Successful treatmen...

journal_title：European journal of neurology

authors： Cirillo E,Del Giudice E,Micheli R,Cappellari AM,Soresina A,Dellepiane RM,Pietrogrande MC,Dell'Era L,Specchia F,Pession A,Plebani A,Pignata C

更新日期：2018-06-01 00:00:00

abstract：:This study is aimed at assessing the prevalence and features of psychotic symptoms in a sample of 180 patients with Alzheimer's disease (AD). Sixty-four patients (35.5% of the sample) showed one or more psychotic symptoms. The presence of these symptoms correlated with the severity of the patients' cognitive impairmen...

journal_title：European journal of neurology

authors： Sala SD,Francescani A,Muggia S,Spinnler H

更新日期：1998-11-01 00:00:00