Patient decisional needs when considering treatment intensification for type 2 diabetes: A qualitative study in China.

Abstract:

AIMS:This study explored decisional needs of patients with type 2 diabetes in China when considering treatment intensification to achieve good glycemic control, from both the patient's and practitioners' perspectives. METHODS:Interviews were conducted with 35 patients, and individual interviews and focus groups with 28 practitioners in Beijing, China. Topic guides based on the Ottawa Decisional Support Framework were modified for the Chinese context. Two interviewers independently extracted and coded transcripts of their notes into-overarching themes. Content analysis was performed to analyze participants' responses. RESULTS:Patients (34/35) reported having tried different medications and some (15/35) visited multiple hospitals and consulted different doctors. Patients' knowledge of medications was suboptimal (26/35), and most patients were not aware of their glucose levels (23/35). Although most were receptive to add-on medications, both patients and practitioners reported a range of uncertainty about the decision, and patients wanted more reliable information. Patients (15/35) and practitioners (19/28) recognized the importance of a trusting relationship when adding medications. Both reported similar values and preferences, but these were rarely discussed when adding medications. Although most patients (32/35) reported that they were capable of making a decision on adding medications, few practitioners (6/28) perceived their patients were capable. CONCLUSIONS:Findings suggest a need for reliable information, more discussion about values and preferences and decision support to help engage patients and practitioners in a shared decision-making process. Decision support tools may facilitate the process for patients with type 2 diabetes in China considering add-on medications.

authors

Zheng H,Toupin-April K,An Y,He S,Sigal RJ,Coyle D,Wells GA,Li G

doi

10.1016/j.diabres.2020.108471

subject

Has Abstract

pub_date

2020-12-01 00:00:00

pages

108471

eissn

0168-8227

issn

1872-8227

pii

S0168-8227(20)30724-5

journal_volume

170

pub_type

杂志文章
  • Diabetes in the Western Pacific Region--past, present and future.

    abstract::In the 2013 issue of the International Diabetes Federation (IDF) Diabetes Atlas, the prevalence of diabetes in the Western Pacific (WP) Region was reported to be 8.6% in 2013, or 138 million adults, and estimated to rise to 11.1%, or 201 million adults, in 2035. The prevalence estimates of impaired glucose tolerance i...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2013.11.012

    authors: Chan JC,Cho NH,Tajima N,Shaw J

    更新日期:2014-02-01 00:00:00

  • Prevalence and geographical distribution of insulin pump therapy in the Central Denmark Region and its association with metabolic parameters.

    abstract:AIMS:Insulin treatment in type 1 diabetes encompasses multiple daily insulin injections (MDI) or continuous subcutaneous insulin infusion (CSII). Both population-based studies and comparative studies regarding CSII use are sparse. The aim of the current study was to describe the prevalence and distribution of CSII use ...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2018.04.042

    authors: Kampmann U,Madsen LR,Bjerg L,Witte DR,Hasselstrøm K,Østergård T,Alstrup K,Møller MK,Dylmer D,Hansen KW

    更新日期:2018-07-01 00:00:00

  • Ten-year mortality and glucose tolerance status in an elderly Finnish population.

    abstract::The aim of this study was to determine the 10-year mortality rate of an elderly population aged 70 years or over (n=379) with reference to glucose tolerance status, taking into account other determinants of excess mortality. The baseline examination during 1991-1992 included a postal questionnaire, a physical examinat...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2004.11.004

    authors: Hiltunen L

    更新日期:2005-07-01 00:00:00

  • The mechanism of exaggerated glucagon response to arginine in diabetes mellitus.

    abstract::As far as exaggerated arginine-induced glucagon secretion in diabetics is concerned, the authors have shown that both the restoration of blood glucose excursions and physiological insulinemia in response to arginine, obtained from an artificial endocrine pancreas (AEP) could normalize the glucagon secretory responses ...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/s0168-8227(85)80002-4

    authors: Kawamori R,Shichiri M,Kikuchi M,Yamasaki Y,Abe H

    更新日期:1985-10-01 00:00:00

  • Effects of evolving lipid-lowering drugs on carbohydrate metabolism.

    abstract::The understanding that statins reduce but not eliminate the cardiovascular risk associated with disturbed lipid metabolism and the existence of forms of dyslipidemia that are unresponsive or only partially responsive to statins have led to the development of many novel lipid-lowering drugs. Accumulating evidence sugge...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,评审

    doi:10.1016/j.diabres.2017.12.012

    authors: Tsimihodimos V,Elisaf M

    更新日期:2018-03-01 00:00:00

  • Association of 48 type 2 diabetes susceptibility loci with fasting plasma glucose and lipid levels in Chinese Hans.

    abstract:AIM:Dozens of susceptibility loci have been identified by type 2 diabetes (T2D) genome wide association study (GWAS) in Europeans. In our previous studies, we systematically evaluated the association of 48 susceptibility loci with T2D risk in Chinese Hans. Because dyslipidemia and hyperglycemia are implicated in the pa...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2018.02.039

    authors: Liu J,Wang L,Qian Y,Dai J,Shen C,Jin G,Hu Z,Shen H

    更新日期:2018-05-01 00:00:00

  • Time-course changes in clinical features of early-onset Japanese type 1 and type 2 diabetes: TWMU hospital-based study.

    abstract::Using a database of patients with type 1 (n=1675) and type 2 (n=2259) diabetes diagnosed before the age of 30 years at the Diabetes Center, Tokyo Women's Medical University (TWMU), in which such Japanese patients have been registered at the time of first visit since the 1960s, we performed a hospital-based study over ...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2008.06.021

    authors: Uchigata Y,Otani T,Takaike H,Miura J,Osawa M,Tukahara S,Kasahara T,Iwamoto Y

    更新日期:2008-10-01 00:00:00

  • To explore the association of Ramadan fasting with symptoms of depression, anxiety, and stress in people with diabetes.

    abstract:AIM:To explore the association of Ramadan fasting with symptoms of depression, anxiety, and stress in people with diabetes. METHODS:This observational study was conducted at Baqai Institute of Diabetology and Endocrinology between May-July 2017. Informed consent was taken from each study participant. Demographic and b...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2020.108545

    authors: Yousuf S,Syed A,Ahmedani MY

    更新日期:2020-11-21 00:00:00

  • Lower limb arterio-venous shunts, autonomic neuropathy and diabetic foot.

    abstract::We have quantitatively assessed the percentage of lower limb arterio-venous (a-v) shunting using a radioisotopic technique and correlated it with autonomic neuropathy evaluated by cardiovascular tests. We have studied three groups of diabetic patients: Group A, 12 non-neuropathic subjects without foot lesions; Group B...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/0168-8227(92)90083-4

    authors: Uccioli L,Mancini L,Giordano A,Solini A,Magnani P,Manto A,Cotroneo P,Greco AV,Ghirlanda G

    更新日期:1992-05-01 00:00:00

  • Soy and the risk of type 2 diabetes mellitus: A systematic review and meta-analysis of observational studies.

    abstract:BACKGROUND:Increasing studies have focused on the relationship between soy intake and type 2 diabetes mellitus risk, but the results are inconsistent. We conduct a meta-analysis to evaluate the relationship. METHODS:The databases of PubMed, Web of Science and Embase were searched up to Dec 2016. A random-effect model ...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.diabres.2018.01.010

    authors: Li W,Ruan W,Peng Y,Wang D

    更新日期:2018-03-01 00:00:00

  • Estimation of influence of gastric emptying on shape of glucose concentration-time profile measured in oral glucose tolerance test.

    abstract:AIMS:To develop a model for simulations of processes in the oral glucose tolerance test (OGTT), using tools of the theory of dynamic systems. METHODS:Frequent sampling OGTT was performed in 13 healthy subjects (6 males and 7 females). Subsequently, employing glucose and insulin concentration-time profiles of the subje...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2006.12.017

    authors: Dedík L,Durisová M,Penesová A,Miklovicová D,Tvrdonová M

    更新日期:2007-09-01 00:00:00

  • Importance of OGTT for diagnosing diabetes mellitus based on prevalence and incidence of retinopathy.

    abstract::Study was made on the necessity and importance of the oral glucose tolerance test (OGTT) for diagnosing diabetes mellitus based on prevalence and incidence of diabetic retinopathy. Subjects were 12208 persons undergoing OGTT between 1965 and 1997. The prevalence of retinopathy was significantly elevated with FPG>/=126...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/s0168-8227(00)00156-x

    authors: Ito C,Maeda R,Ishida S,Harada H,Inoue N,Sasaki H

    更新日期:2000-08-01 00:00:00

  • Global and regional estimates and projections of diabetes-related health expenditure: Results from the International Diabetes Federation Diabetes Atlas, 9th edition.

    abstract:AIMS:Diabetes and its complications have a significant economic impact on individuals and their families, health systems and national economies. METHODS:The direct health expenditure of diabetes was calculated relying on the following inputs: diagnosed and undiagnosed diabetes prevalence estimates, United Nations popu...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2020.108072

    authors: Williams R,Karuranga S,Malanda B,Saeedi P,Basit A,Besançon S,Bommer C,Esteghamati A,Ogurtsova K,Zhang P,Colagiuri S

    更新日期:2020-04-01 00:00:00

  • Dropout of young non-insulin-dependent diabetics from diabetic care.

    abstract::We investigated the follow-up status and prognosis of 109 patients with non-insulin-dependent diabetes mellitus aged from 10 to 19 years old (66 males and 43 females). Patients who had not attended hospital for at least 20 months up to the end of September 1990 were regarded as defaulters, and were surveyed by questio...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/0168-8227(94)90114-7

    authors: Kawahara R,Amemiya T,Yoshino M,Miyamae M,Sasamoto K,Omori Y

    更新日期:1994-07-01 00:00:00

  • Abnormal transient rise in hepatic glucose production after oral glucose in non-insulin-dependent diabetic subjects.

    abstract::A transient rise in hepatic glucose production (HGP) after an oral glucosa load has been reported in some insulin-resistant states such as in obese fa/fa Zucker rats. The aim of this study was to determine whether this rise in HGP also occurs in subjects with established non-insulin-dependent diabetes mellitus (NIDDM)...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/0168-8227(95)01067-n

    authors: Thorburn A,Litchfield A,Fabris S,Proietto J

    更新日期:1995-05-01 00:00:00

  • Elevated liver enzymes in women with a family history of diabetes.

    abstract::Both elevated liver enzymes and a family history of diabetes mellitus (FHDM) are independent risk factors for type 2 diabetes. This study evaluates the epidemiological association between elevated liver enzymes and FHDM. Subjects included 3512 women workers without diabetes, hepatitis, a smoking habit, or a history of...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2007.10.032

    authors: Inoue K,Matsumoto M,Miyoshi Y,Kobayashi Y

    更新日期:2008-03-01 00:00:00

  • Awareness of pathophysiological concepts of type 2 diabetes: a survey in 847 physicians.

    abstract:AIMS:The aim of the study was to determine physicians' knowledge of specific concepts generally implicated in the pathophysiology of type 2 diabetes (T2D). METHODS:A multiple choice online survey was completed by 847 physicians, of which 516 were engaged in primary care (PCP) and 331 in specialized care (SCP) in the U...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2006.09.037

    authors: Busse FP,Denti V,Stumvoll M

    更新日期:2007-06-01 00:00:00

  • Exercise training in Otsuka Long-Evans Tokushima Fatty rat, a model of spontaneous non-insulin-dependent diabetes mellitus: effects on the B-cell mass, insulin content and fibrosis in the pancreas.

    abstract::The effects of exercise on alterations in the amount of B-cell mass, insulin content and fibrous tissue present in the pancreas were examined for a diabetic state induced by a 70% pancreatectomy and a prediabetic state in Otsuka Long-Evans Tokushima Fatty (OLETF) rat, a model for the spontaneous development of non-ins...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/s0168-8227(96)01357-5

    authors: Shima K,Zhu M,Noma Y,Mizuno A,Murakami T,Sano T,Kuwajima M

    更新日期:1997-02-01 00:00:00

  • Lower waist-circumference cutoff point for the assessment of cardiometabolic risk in Koreans.

    abstract:AIMS:To determine the appropriate cutoff value of waist circumference associated with cardiometabolic risk factors in Koreans. METHODS:Clinical and laboratory data on 31,076 Korean adults (age 20-89 years, 40% women) were recorded at regular health check-ups. Receiver operating characteristic curves were used to deter...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2009.04.009

    authors: Kim HK,Kim CH,Park JY,Lee KU

    更新日期:2009-07-01 00:00:00

  • Altered expression of WFS1 and NOTCH2 genes associated with diabetic nephropathy in T2DM patients.

    abstract:AIM:The increased incidence of type 2 diabetes mellitus (T2DM) and the importance of early identification and management of its complications, especially diabetic nephropathy (DN), have spotted the light on genetic factors that increase risk of T2DM and its related nephropathy. The present study aimed at investigating ...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2018.03.053

    authors: Sharaf SA,Kantoush NA,Ayoub DF,Ibrahim AA,Abdelaal AA,Aziz RA,ElHefnawi MM,Ahmed AN

    更新日期:2018-06-01 00:00:00

  • C679X loss-of-function PCSK9 variant lowers fasting glucose levels in a black South African population: A longitudinal study.

    abstract:AIMS:To determine the longitudinal association of the loss-of-function (LOF) PCSK9 variants (C679X and A443T), proxies of PCSK9 inhibitor drugs, with LDL-C, fasting glucose and glycated hemoglobin. METHODS:We conducted a five year, longitudinal study, nested within the Prospective Urban and Rural Epidemiology study, a...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2018.09.012

    authors: Chikowore T,Cockeran M,Conradie KR,van Zyl T

    更新日期:2018-10-01 00:00:00

  • Diabetes mellitus with left transverse sinus thrombosis and right transverse sinus aplasia.

    abstract::A 67-year-old woman with diabetes mellitus was hospitalized due to a throbbing headache. She appeared neurologically normal, except for meningeal irritation. The cerebrospinal fluid pressure was high. There was increased fluid protein without an increased cell count. Brain CT scan showed no abnormality, however, brain...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/s0168-8227(00)00207-2

    authors: Nagai T,Tomizawa T,Tonooka N,Mita Y,Misumi S,Mori M

    更新日期:2001-01-01 00:00:00

  • Prognostic nomogram and score to predict renal survival of patients with biopsy-proven diabetic nephropathy.

    abstract:AIMS:Both clinical and pathogenetic markers for accurate prediction of end-stage renal disease in diabetic nephropathy (DN) are lacking. This study aimed to establish an effective prognostic nomogram and a score for renal survival (RS) in biopsy-proven DN. METHODS:Analyses were derived from 110 DN patients who underwe...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2019.107809

    authors: Jiang S,Yu T,Zhang Z,Fang J,Wang Y,Yang Y,Liu L,Zou G,Gao H,Zhuo L,Li W

    更新日期:2019-09-01 00:00:00

  • Premature loss of muscle mass and function in type 2 diabetes.

    abstract:INTRODUCTION:Muscle mass and function are among the most relevant factors that contribute to an optimal quality of life, and are strong predictors of mortality in the elderly. Loss of lean tissues and deterioration of muscle function have been described as one of the many complications of type 2 diabetes mellitus (DM2)...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2016.04.011

    authors: Guerrero N,Bunout D,Hirsch S,Barrera G,Leiva L,Henríquez S,De la Maza MP

    更新日期:2016-07-01 00:00:00

  • Morphological changes in autonomic ganglionic cells of the heart in diabetic patients.

    abstract::To clarify the histological changes of the cardiac autonomic nervous system in diabetes mellitus, ganglionic cells of the hearts of autopsy cases were examined light microscopically. In 7 severely diabetic patients, the ganglionic neurons showed cellular contraction, cytoplasmic condensation and poor staining of Nissl...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/s0168-8227(86)80014-6

    authors: Tsujimura T,Nunotani H,Fushimi H,Inoue T

    更新日期:1986-06-01 00:00:00

  • Health beliefs among individuals at increased familial risk for type 2 diabetes: implications for prevention.

    abstract:AIM:To evaluate perceived risk, control, worry, and severity about diabetes, coronary heart disease (CHD) and stroke among individuals at increased familial risk of diabetes. METHODS:Data analyses were based on the Family Healthware™ Impact Trial. Baseline health beliefs were compared across three groups: (1) no famil...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2011.12.017

    authors: Dorman JS,Valdez R,Liu T,Wang C,Rubinstein WS,O'Neill SM,Acheson LS,Ruffin MT 4th,Khoury MJ

    更新日期:2012-05-01 00:00:00

  • Diabetes in the Melanesian and Indian peoples of Fiji: a study of risk factors.

    abstract::Epidemiological risk factor patterns for diabetes mellitus determined by hemoglobin A1 and fasting blood glucose criteria were compared in the biethnic (Melanesian and Indian) nation of Fiji. The 2 diagnostic criteria elicited essentially similar risk factor patterns in Indians but ranking of predictors was altered in...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/s0168-8227(87)80050-5

    authors: Hoskins PL,Handelsman DJ,Hannelly T,Silink M,Yue DK,Turtle JR

    更新日期:1987-09-01 00:00:00

  • Further evidence for insulin hypersecretion not as an initial event but as a consequence of body growth and maturation in juvenile-onset obesity.

    abstract::According to our previous study, hyperinsulinism develops not before 10 years of age despite the presence of obesity but during the maturation years of 10-20. We aimed here at examining the growth-related islet B-cell change together with pituitary activity in non-familial juvenile obesity. Measurement of 24 h urine h...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/s0168-8227(86)80064-x

    authors: Maruhama Y,Hikichi I,Hashimoto T,Saito F,Ninomiya K

    更新日期:1986-05-01 00:00:00

  • A case of chronic hepatitis C developing insulin-dependent diabetes mellitus associated with various autoantibodies during interferon therapy.

    abstract::We report a case of chronic hepatitis C presenting insulin-dependent diabetes mellitus (IDDM) associated with various autoantibodies including possible anti-insulin receptor antibody (AIRA) during interferon (IFN) therapy. A 57-year-old man having chronic hepatitis C virus (HCV) infection with chronic thyroiditis rece...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/s0168-8227(00)00143-1

    authors: Uto H,Matsuoka H,Murata M,Okamoto T,Miyata Y,Hori T,Ido A,Hirono S,Hayashi K,Tsubouchi H

    更新日期:2000-08-01 00:00:00

  • Factors predicting the need for insulin therapy in patients with gestational diabetes mellitus.

    abstract:AIM:To determine the possible factors predicting the insulin requirement in pregnancies complicated by gestational diabetes mellitus (GDM). METHOD:A total of 294 patients with GDM diagnosed by the 100-g/3-h oral glucose tolerance test (OGTT) were studied. The following factors were analyzed: maternal age, nulliparity,...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2009.12.023

    authors: Sapienza AD,Francisco RP,Trindade TC,Zugaib M

    更新日期:2010-04-01 00:00:00