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Prevalence and geographical distribution of insulin pump therapy in the Central Denmark Region and its association with metabolic parameters.

Abstract：

AIMS:Insulin treatment in type 1 diabetes encompasses multiple daily insulin injections (MDI) or continuous subcutaneous insulin infusion (CSII). Both population-based studies and comparative studies regarding CSII use are sparse. The aim of the current study was to describe the prevalence and distribution of CSII use among adults with type 1 diabetes in the Central Denmark Region and to compare metabolic control in CSII-treated patients to those treated with MDI. METHODS:A database was constructed using the Danish Adult Diabetes Registry in 2014/2015 in combination with an audit of the patients' medical records. RESULTS:3909 adults with type 1 diabetes patients were included. The proportion of patients treated with CSII differed significantly between the 8 regional hospitals from 12.0% to 31.1%. CSII users had a significantly lower HbA1c compared to MDI treated patients (7.6% (60 mmol/mol) versus 8.0% (64 mmol/mol)) in unadjusted analyses. After adjustment for clinically relevant characteristics the difference between CSII and MDI-treated patients was attenuated, but remained statistically significant. CONCLUSION:The distribution of CSII differed markedly between hospitals and CSII users had better glycemic control, even after adjustment for sex, age, BMI, diabetes duration, smoking, use of lipid-lowering and blood pressure-lowering medication.

journal_name

Diabetes Res Clin Pract

journal_title

Diabetes research and clinical practice

authors

Kampmann U,Madsen LR,Bjerg L,Witte DR,Hasselstrøm K,Østergård T,Alstrup K,Møller MK,Dylmer D,Hansen KW

doi

10.1016/j.diabres.2018.04.042

subject

Has Abstract

pub_date

2018-07-01 00:00:00

pages

148-155

eissn

0168-8227

issn

1872-8227

pii

S0168-8227(17)32014-4

journal_volume

141

pub_type

杂志文章

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