Noninvasive assessment of cerebral collateral blood supply through the ophthalmic artery.

abstract：BACKGROUND AND PURPOSE:The treatment of large brain arteriovenous malformations (BAVMs) is challenging, and embolization alone is seldom curative. The study goal is to enhance the efficacy of arteriovenous malformation embolization by adding a beta-emitting isotope to the embolic agent. METHODS:The pig rete mirabile w...

journal_title：Stroke

authors： Roy D,Soucy JP,Hartman NG,Janicki C,Weill A,Guilbert F,Papineau K,Raymond J

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Eligibility criteria determine the external validity (generalizability) of the results of randomized controlled trials. To increase the number of outcome events, and hence statistical power, some recent stroke prevention trials have required additional vascular risk factors for eligibility. METH...

journal_title：Stroke

authors： Howard SC,Algra A,Warlow CP,Rothwell PM

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although the cause of stroke among patients with patent foramen ovale (PFO) may be due to paradoxical cerebral embolism (PCE), this mechanism is often difficult to prove. The aim of our study was to evaluate the association between brain imaging findings suggestive of embolism and PFO among ische...

journal_title：Stroke

authors： Steiner MM,Di Tullio MR,Rundek T,Gan R,Chen X,Liguori C,Brainin M,Homma S,Sacco RL

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this study was to assess the costs and cost-effectiveness of intravenous thrombolysis treatment with alteplase (Actilyse) of acute ischemic stroke with 24-hour in-house neurology coverage and use of magnetic resonance imaging. METHODS:A health economic model was designed to calculate ...

journal_title：Stroke

authors： Ehlers L,Andersen G,Clausen LB,Bech M,Kjølby M

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To assess the association of lesion location and risk of aspiration and to establish predictors of transient versus extended risk of aspiration after supratentorial ischemic stroke. METHODS:Atlas-based localization analysis was performed in consecutive patients with MRI-proven first-time acute s...

journal_title：Stroke

authors： Galovic M,Leisi N,Müller M,Weber J,Abela E,Kägi G,Weder B

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In a previous study from our laboratory, ritanserin, a specific 5-HT2 serotonin receptor antagonist, reduced ischemic damage in the setting of transient global ischemia. In this study, we examined the effect of ritanserin on ischemic cerebral blood flow, systemic blood pressure, and infarct volum...

journal_title：Stroke

authors： Takagi K,Ginsberg MD,Globus MY,Busto R,Dietrich WD

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It was found that glutamate, a major neurotransmitter, is vasoactive in the cerebral circulation. However, the mechanism is unclear. This study was designed to investigate the role of nitric oxide (NO) and N-methyl-D-aspartate (NMDA) receptors in cerebral arteriolar dilation to glutamate. METHOD...

journal_title：Stroke

authors： Meng W,Tobin JR,Busija DW

更新日期：1995-05-01 00:00:00

abstract：:Background and Purpose- Several vascular risk factors are known to be associated with the occurrence of intracranial aneurysms (IAs). Coronary artery calcium (CAC), which reflects the atherosclerotic burden of the coronary arteries, is a known predictor of cardiovascular events and stroke. We investigated the relation...

journal_title：Stroke

authors： Cho BH,Kim JH,Suh SH,Baik SJ,Lee HS,Kim J,Lee KY

更新日期：2019-06-01 00:00:00

abstract：:We measured cerebrovascular reactivity to carbon dioxide in the cerebral cortex and the subcortical white matter of 12 healthy adult volunteers (four young subjects aged 21-24, four middle-aged subjects aged 34-40, and four elderly subjects aged 62-85 years). Blood flow was computed from the concentration history of x...

journal_title：Stroke

authors： Reich T,Rusinek H

更新日期：1989-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It remains unknown whether the effects of 0.6 mg/kg alteplase differ with occlusion site of the middle cerebral artery (MCA). We therefore evaluated the effects of 0.6 mg/kg intravenous alteplase in patients with different sites of MCA occlusion. METHODS:An exploratory analysis was made of 57 pa...

journal_title：Stroke

authors： Hirano T,Sasaki M,Mori E,Minematsu K,Nakagawara J,Yamaguchi T,Japan Alteplase Clinical Trial II Group.

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Spontaneous echo contrast (SEC) is thought to represent a risk factor for cardioembolic stroke. In vitro studies suggest that SEC results from interaction between red cells and fibrinogen. To better understand the relation between SEC and stroke and to investigate the in vivo genesis of SEC, we e...

journal_title：Stroke

authors： Briley DP,Giraud GD,Beamer NB,Spear EM,Grauer SE,Edwards JM,Clark WM,Sexton GJ,Coull BM

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Chlamydia pneumoniae infection has recently become noteworthy in relation to atherosclerosis. We investigated by immunohistochemistry the distribution of C pneumoniae infection in the atherosclerotic carotid artery. METHODS:Twenty carotid atherosclerotic lesions that were resected during carotid...

journal_title：Stroke

authors： Yamashita K,Ouchi K,Shirai M,Gondo T,Nakazawa T,Ito H

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The role of the cerebral microcirculation in delayed ischemia after subarachnoid hemorrhage remains obscure. To test the hypothesis that cerebral arterioles have a reduced capacity to dilate after subarachnoid hemorrhage, we studied the microvascular responses to papaverine (PPV) in patients unde...

journal_title：Stroke

authors： Pennings FA,Albrecht KW,Muizelaar JP,Schuurman PR,Bouma GJ

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Oxidative damage of mitochondrial DNA (mtDNA) in the ischemic brain is expected after ischemia/reperfusion injury. A recent study demonstrated limited patterns of mtDNA deletion in the brain after ischemia/reperfusion. We studied the ischemia/reperfusion-induced global changes of mtDNA integrity ...

journal_title：Stroke

authors： Chen H,Hu CJ,He YY,Yang DI,Xu J,Hsu CY

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The lipophilic calcium channel antagonist flunarizine has been demonstrated to be neuroprotective in several models of cerebral ischemia. Ischemic spinal cord injury may have a similar pathophysiology and hence may respond in a similar fashion. This study was designed to investigate the effects o...

journal_title：Stroke

authors： Johnson SH,Kraimer JM,Graeber GM

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The effect of statins on progression of carotid intima-media complex thickness (IMT) has been shown exclusively in nonstroke Western patients. This study aimed to determine the effect of low-dose pravastatin on carotid IMT in Japanese patients with noncardioembolic ischemic stroke. METHODS:This ...

journal_title：Stroke

authors： Koga M,Toyoda K,Minematsu K,Yasaka M,Nagai Y,Aoki S,Nezu T,Hosomi N,Kagimura T,Origasa H,Kamiyama K,Suzuki R,Ohtsuki T,Maruyama H,Kitagawa K,Uchiyama S,Matsumoto M,J-STARS Investigators.

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We evaluated the impact of a primary stroke center (PSC) destination policy in a major metropolitan city and used geographic modeling to evaluate expected changes for a comprehensive stroke center policy. METHODS:We identified suspected stroke emergency medical services encounters from 1/1/2004 ...

journal_title：Stroke

authors： Mullen MT,Pajerowski W,Messé SR,Mechem CC,Jia J,Abboud M,David G,Carr BG,Band R

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this study was to validate the diagnosis of self-reported stroke. METHODS:During 1994-1995, 27 159 people attended a population health survey in the community of Tromso, Norway, a response rate of 77%. A total of 418 attenders reported a history of stroke. In 1997, all individuals wit...

journal_title：Stroke

authors： Engstad T,Bonaa KH,Viitanen M

更新日期：2000-07-01 00:00:00

abstract：:Regional cerebral blood flow, blood volume, fractional oxygen extraction, and oxygen consumption were measured by positron emission tomography in 4 stroke patients prior to and 6 months following omental transposition surgery. Preoperatively, 3 patients showed the typical picture of established infarction with a match...

journal_title：Stroke

authors： Herold S,Frackowiak RS,Neil-Dwyer G

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral ischemia and stroke are leading causes of morbidity and mortality. An approach to protecting the brain during ischemia is to try to increase the delivery of oxygen via the residual blood flow through and around ischemic tissue. To test this hypothesis, we used a novel oxygen delivery age...

journal_title：Stroke

authors： Watson JC,Doppenberg EM,Bullock MR,Zauner A,Rice MR,Abraham D,Young HF

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The best management of patients with unruptured brain arteriovenous malformations (BAVM) is controversial. In this study, we analyzed the stroke rate and functional outcomes of patients having stereotactic radiosurgery (SRS) for unruptured BAVM using the same eligibility criteria and primary end ...

journal_title：Stroke

authors： Pollock BE,Link MJ,Brown RD

更新日期：2013-02-01 00:00:00

abstract：:We have investigated the effects of a reduced regional or a reduced body temperature, on pial arteriolar response to a variety of vasoactive stimuli. This has been done by studying the effects of these stimuli on groups of mice with different body temperatures, or with different temperatures of the artificial cerebros...

journal_title：Stroke

authors： Rosenblum WI,Segreti AC

更新日期：1978-11-01 00:00:00

abstract：:Background and Purpose- The purpose of this study was to conduct a meta-analysis of CVOTs (cardiovascular outcome trials) to evaluate the effect of glucagon-like peptide-1 receptor agonists therapy in reducing the risk of stroke in patients with type 2 diabetes mellitus. Methods- PubMed and other electronic sources we...

journal_title：Stroke

authors： Bellastella G,Maiorino MI,Longo M,Scappaticcio L,Chiodini P,Esposito K,Giugliano D

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Telomerase reverse transcriptase (TERT) is tightly related to the resistance of cells to stress and injury. However, little is known about the roles of TERT in the nervous system. We try to investigate the effects of TERT on the function of astrocytes in developing rat brains subjected to hypoxia...

journal_title：Stroke

authors： Qu Y,Duan Z,Zhao F,Wei D,Zhang J,Tang B,Li J,Yang C,Mu D

更新日期：2011-12-01 00:00:00

abstract：:A 25-year-old black man with sarcoidosis presented with transient ischemic attacks followed by sudden, persistent right hemiparesis. He gave a history of recent, recurrent lower motor neuron facial palsy. Computed tomography demonstrated an infarct in the left internal capsule. Chest x-ray film showed bilateral hilar ...

journal_title：Stroke

authors： Brown MM,Thompson AJ,Wedzicha JA,Swash M

更新日期：1989-03-01 00:00:00

abstract：:Various concentrations of acetylcholine (ACh) produced dose dependent relaxations of isolated, helical preparations of human cerebral arteries and these responses were blocked by atropine. The median effective concentration (EC50) of ACh was 6.1 +/- 0.2 X 10(-6)M. ACh produced dual responses in isolated dog cerebral a...

journal_title：Stroke

authors： Tsukahara T,Usui H,Taniguchi T,Shimohama S,Fujiwara M,Handa H

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Perihematomal edema formation and consequent cell death contribute to the delayed brain injury evoked by intracerebral hemorrhage (ICH). We aimed to evaluate the effect of α7 nicotinic acetylcholine receptor (α7nAChR) stimulation on behavior, brain edema, and neuronal apoptosis. Furthermore, we a...

journal_title：Stroke

authors： Krafft PR,Altay O,Rolland WB,Duris K,Lekic T,Tang J,Zhang JH

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Hyperpolarization of vascular muscle in response to activation of potassium channels is a major mechanism of vasodilatation. In cerebral blood vessels, four different potassium channels have been described: ATP-sensitive potassium channels, calcium-activated potassium channels, delayed rectifier potassium ch...

journal_title：Stroke

authors： Kitazono T,Faraci FM,Taguchi H,Heistad DD

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Chinese patients largely experience acute ischemic stroke (AIS) because of large artery atherosclerosis rather than cardioembolism, and whether tirofiban is safe and effective in these patients treated with endovascular thrombectomy (ET) is unknown. This study evaluated the safety and efficacy of...

journal_title：Stroke

authors： Zhao W,Che R,Shang S,Wu C,Li C,Wu L,Chen J,Duan J,Song H,Zhang H,Ling F,Wang Y,Liebeskind D,Feng W,Ji X

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of this study was to assess the association of vitamin D deficiency and indices of mineral metabolism with subclinical carotid markers that predict cardiovascular events. METHODS:Two hundred three community-dwelling adults (Northern Manhattan Study; age, 68 ± 11; age range, 50 to 93 ...

journal_title：Stroke

authors： Carrelli AL,Walker MD,Lowe H,McMahon DJ,Rundek T,Sacco RL,Silverberg SJ

更新日期：2011-08-01 00:00:00