Impact of lymph-node metastasis site in patients with thoracic esophageal cancer.

Abstract:

BACKGROUND AND OBJECTIVES:We retrospectively compared surgical outcomes between patients with intra-thoracic and extra-thoracic (cervical and abdominal) lymph-node metastasis. METHODS:The study population comprised 96 patients with lymph-node metastasis who had undergone curative esophagectomy for thoracic esophageal cancer. The patients were grouped according to whether the site of lymph-node metastasis was intra-thoracic, extra-thoracic, or both intra-thoracic and extra-thoracic. The patient characteristics, survival time, and prognostic factors were compared. RESULTS:The most significant difference in disease-specific survival was detected at a threshold value of four metastatic lymph nodes. Lymph-node metastasis was observed at intra-thoracic sites in 41 patients, at extra-thoracic sites in 20 patients, and at both intra-thoracic and extra-thoracic sites in 35 patients. Intra-thoracic lymph-node metastasis was frequently observed in patients with middle and upper thoracic esophageal cancer. There was no difference in the number of metastatic lymph nodes between patients with intra-thoracic and extra-thoracic lymph-node metastasis. Multivariate analysis revealed that the number of metastatic lymph nodes was an independent prognostic factor, whereas the site of metastatic lymph nodes was not. CONCLUSIONS:These findings suggest that the surgical outcomes in patients with thoracic esophageal cancer depend on the number, but not the site, of metastatic lymph nodes after curative esophagectomy.

journal_name

J Surg Oncol

authors

Kunisaki C,Makino H,Kimura J,Oshima T,Fujii S,Takagawa R,Kosaka T,Ono HA,Akiyama H

doi

10.1002/jso.21425

subject

Has Abstract

pub_date

2010-01-01 00:00:00

pages

36-42

issue

1

eissn

0022-4790

issn

1096-9098

journal_volume

101

pub_type

杂志文章
  • Ablative therapies in adrenal tumors: primary and metastatic.

    abstract::A large number of adrenal tumors are now identified either incidentally or associated with a metastatic workup for cancer. While the vast majority of these lesions are benign, those that prove to be primary or secondary cancers are traditionally treated with surgical resection. A wide variety of alternative, less inva...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.23191

    authors: Pua BB,Solomon SB

    更新日期:2012-10-01 00:00:00

  • Locally advanced rectal cancer: a multivariate analysis of outcome risk factors.

    abstract:BACKGROUND AND OBJECTIVES:Stages II and III rectal tumors are known as locally advanced rectal cancer (LARC) because they are characterized by a high incidence of local and distant relapses and a low probability of long-term survival. Adjuvant treatments have been advocated to ameliorate overall survival (OS), local re...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/1096-9098(200005)74:1<2::aid-jso2>3.0.co;2

    authors: Bufalari A,Boselli C,Giustozzi G,Moggi L

    更新日期:2000-05-01 00:00:00

  • Unusual origins of Pseudomyxoma peritonei.

    abstract::Pseudomyxoma peritonei is a rare neoplastic condition in that gelatinous intraperitoneal fluid collections and mucinous implants on the peritoneal surfaces and omentum are found. The pathological origin is usually an adenoma or well-differentiated adenocarcinoma of the appendix. A smaller number of cases arises from o...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/1096-9098(200012)75:4<270::aid-jso9>3.0.co

    authors: de Bree E,Witkamp A,Van De Vijver M,Zoetmulde F

    更新日期:2000-12-01 00:00:00

  • Sarcoidosis of the pancreas.

    abstract::We report a case of pancreatic sarcoidosis in a patient with radiographic and clinical findings suggestive of pancreatic cancer. Clinically apparent involvement of the pancreas is uncommon in patients with known sarcoidosis and is distinctly unusual as the initial presentation of disease. Sarcoid involvement of the pa...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.2930540215

    authors: Brady MS,Garfein CF,Klimstra D,Brenann MF

    更新日期:1993-10-01 00:00:00

  • The characteristics of thymoma with myasthenia gravis: a 28-year experience.

    abstract::Of 134 patients with thymoma, 79 (59%) also had myasthenia gravis (MG). The thymoma with MG differed from that in the absence of MG in the following aspects: The ratio of lymphocytes to epithelial cells in the tumor was larger, the polygonal cell type was more prominent (i.e., in 83% of the MG patients this cell type ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930380305

    authors: Monden Y,Uyama T,Taniki T,Hashimoto J,Fujii Y,Nakahara K,Kawashima Y,Masaoka A

    更新日期:1988-07-01 00:00:00

  • Adenocarcinoma arising in association with gastric heterotopic pancreas: A case report and review of the literature.

    abstract::We report a case of adenocarcinoma arising in a focus of heterotopic pancreas, occurring in the stomach of a 52-year-old man. The patient presented with gastric outlet obstruction. Radiographic studies revealed thickening of the gastric wall, but endoscopy failed to reveal a mucosal abnormality. A 50% distal gastrecto...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.20087

    authors: Emerson L,Layfield LJ,Rohr LR,Dayton MT

    更新日期:2004-07-15 00:00:00

  • Neoadjuvant therapy of locally advanced gastric cancer.

    abstract::Treatment of gastric cancer has evolved with the advent of randomized trials demonstrating chemotherapeutic agents with efficacy in advanced disease. Level I evidence supports delivering chemotherapy in the neoadjuvant setting; the data shows improvement in progression-free and overall survival. A clinical response to...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.21483

    authors: Mezhir JJ,Tang LH,Coit DG

    更新日期:2010-03-15 00:00:00

  • Heterotopic ossification in rectal cancer: Rare finding with a novel proposed mechanism.

    abstract::The rare finding of heterotopic ossification in a case of primary rectal adenocarcinoma is described along with a review of the literature. Immunohistochemistry for a bone morphogenic protein (BMP-2) and fibroblast growth factor (FGF-2), both of which induce and stimulate bone formation, was performed and revealed ove...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.10181

    authors: Kypson AP,Morphew E,Jones R,Gottfried MR,Seigler HF

    更新日期:2003-02-01 00:00:00

  • Recurrent pleomorphic adenoma of the parotid gland: Institutional experience and review of the literature.

    abstract:BACKGROUND:Recurrent pleomorphic adenoma (PA) of the parotid gland is a challenging surgical issue with controversy regarding management and long term outcome. METHODS:All patients who were operated for recurrent PA of the parotid gland between the years 1991 and 2013 were reviewed. Patient demographics, clinicopathol...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.24392

    authors: Abu-Ghanem Y,Mizrachi A,Popovtzer A,Abu-Ghanem N,Feinmesser R

    更新日期:2016-11-01 00:00:00

  • Comparison of R1 and R2 gastrectomy for gastric cancer in patients over 80 years of age.

    abstract::To evaluate the benefit of R2 gastrectomy for gastric cancer in Japanese patients over 80 years of age, data on 93 patients who underwent gastrectomy between 1967 and 1989 were collected retrospectively from charts filed in the Kyushu University Hospital and two affiliated national hospitals. Of 93 patients, 62 had a ...

    journal_title:Journal of surgical oncology

    pub_type: 临床试验,杂志文章

    doi:10.1002/jso.2930480213

    authors: Korenaga D,Baba H,Kakeji Y,Orita H,Haraguchi M,Maehara Y,Saku M,Sugimachi K

    更新日期:1991-10-01 00:00:00

  • Expression of interleukin (IL)-12 mRNA in gastric carcinoma specimens: cellular antitumor immune responses.

    abstract:BACKGROUND AND OBJECTIVES:Several tumor-related antigen peptides that are recognized by autologous cytolytic T cells (CTL) have been reported. However, most human solid tumors, including gastric carcinoma, are only weakly immunogenic. In this study, we focused on interleukin (IL)-12 and interferon-gamma (IFN-gamma) as ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/(sici)1096-9098(199801)67:1<11::aid-jso3>3

    authors: Katano M,Nakamura M,Kuwahara A,Fujimoto K,Matsunaga H,Miyazaki K,Morisaki T

    更新日期:1998-01-01 00:00:00

  • Intravenous electrocardiography helps inexperienced operators to place totally implantable venous access device more accurately.

    abstract:BACKGROUND:Proper tip position is a major determinant of totally implantable venous access device (TIVAD) outcome. The aim of this study is to analyze the potential utilization of intravenous electrocardiography (IV-ECG) to help inexperienced operators for TIVAD placement. PATIENTS AND METHODS:This is a retrospective,...

    journal_title:Journal of surgical oncology

    pub_type: 临床试验,杂志文章

    doi:10.1002/jso.23000

    authors: Wang YC,Huang CH,Lin FS,Lin WY,Fan SZ,Lin CP,Sun WZ

    更新日期:2012-06-15 00:00:00

  • Fine-needle aspiration cytology of abdominal masses.

    abstract::An investigation of the role of blind fine-needle aspiration cytology (FNAC) in the assessment of palpable abdominal masses was carried out on 196 patients: 124 hepatic, 30 retroperitoneal, and 42 other masses. All of the smears were stained either by Papanicolaou stain or by hematoxylin and eosin stain. The results o...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930440105

    authors: Khanna AK,Misra MK,Khanna A,Misra VK,Khanna S

    更新日期:1990-05-01 00:00:00

  • Malignant pheochromocytoma and paraganglioma: a population level analysis of long-term survival over two decades.

    abstract:BACKGROUND AND OBJECTIVES:Pheochromocytoma (PHEO) and paraganglioma (PGL) are rare tumors. Aims of this study were to describe and to compare demographic, clinical, pathologic, and survival characteristics of malignant PHEO and PGL. METHODS:Patients were identified in SEER, 1988-2009. Analyses included chi-square, ANO...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.23297

    authors: Goffredo P,Sosa JA,Roman SA

    更新日期:2013-05-01 00:00:00

  • Effective and efficient lymphaticovenular anastomosis using preoperative ultrasound detection technique of lymphatic vessels in lower extremity lymphedema.

    abstract:BACKGROUND:Identification of functional lymphatic vessels and localization of lymphatic vessels are important for lymphaticovenular anastomosis (LVA). Indocyanine green (ICG) lymphography is useful for localization of superficial lymphatic vessels where dermal backflow is not observed, but not for lymphatic vessels in ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.24812

    authors: Hayashi A,Hayashi N,Yoshimatsu H,Yamamoto T

    更新日期:2018-02-01 00:00:00

  • Predictors of postoperative morbidity after laparoscopic versus open radical hysterectomy plus external beam radiotherapy: a propensity-matched comparison.

    abstract:BACKGROUND:Identification of peri-operative variables predicting postoperative morbidity may improve postoperative patients' care. We aimed to identify patients' characteristics and operative factors predictive of early (≤ 30-day) and late (≤ 6-month) morbidity in cervical cancer patients undergoing surgery plus extern...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.23747

    authors: Bogani G,Cromi A,Serati M,Di Naro E,Uccella S,Donadello N,Ghezzi F

    更新日期:2014-12-01 00:00:00

  • The neoadjuvant therapy of colorectal hepatic metastases and the role of biologic sensitizing and resistance factors.

    abstract::Liver metastasis represents a common systemic complication of colorectal cancers (CRCs). Partial liver resection has been demonstrated to result in long-term survival in certain well-selected patients with otherwise well-controlled systemic disease. Neoadjuvant therapy has been demonstrated to result in improved resec...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.21691

    authors: Wanebo HJ,Berz D

    更新日期:2010-12-15 00:00:00

  • Spontaneous regression of breast carcinoma: follow-up report and literature review.

    abstract::A case of spontaneous complete regression of metastatic breast carcinoma (malignant pleural effusion and bone metastases) with previously reported from M. D. Anderson Hospital and Tumor Institute. The patient did not receive any form of hormonal manipulation or systemic chemotherapy. This patient has now relapsed afte...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930190107

    authors: Ross MB,Buzdar AU,Hortobagyi GN,Lukeman JM

    更新日期:1982-01-01 00:00:00

  • Malignancy and differentiation of neoplastic epithelial cells of thymoma.

    abstract::Fifteen fetal thymuses and 100 thymomas were examined concerning the degree of differentiation of thymic epithelial cells by light and electron microscopy. The following results were obtained. The embryologic process of the fetal thymus was categorized into four stages (8, 12, 15, and 17 weeks or more of gestation) ba...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930310212

    authors: Monden Y,Tanioka T,Maeda M,Masaoka A,Nakahara K,Kawashima Y,Kitamura H

    更新日期:1986-02-01 00:00:00

  • A prediction model for lymph node metastasis in early-stage gastric cancer: Toward tailored lymphadenectomy.

    abstract:BACKGROUND:The aim of this study was to develop a prediction model for the presence and location of lymph node metastasis (LNM) in early gastric cancer. METHOD:We reviewed medical records of 4 929 patients who underwent radical gastrectomy for early gastric cancer. Variables of age, sex, lymphatic invasion, depth of i...

    journal_title:Journal of surgical oncology

    pub_type: 临床试验,杂志文章

    doi:10.1002/jso.25628

    authors: Kim SM,Lee H,Min BH,Kim JJ,An JY,Choi MG,Bae JM,Kim S,Sohn TS,Lee JH

    更新日期:2019-09-01 00:00:00

  • Outcomes and clinical predictors of improved survival in a patients undergoing pulmonary metastasectomy for sarcoma.

    abstract:BACKGROUND:Pulmonary metastasectomy (PM) for metastatic sarcoma can result in long-term survival. The purpose of this study was to describe factors associated with survival in a series of patients undergoing PM for metastatic sarcoma. METHODS:We reviewed all patients undergoing PM for metastatic sarcoma over a 12-year...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.23961

    authors: Dossett LA,Toloza EM,Fontaine J,Robinson LA,Reed D,Druta M,Letson DG,Zager JS,Gonzalez RJ

    更新日期:2015-07-01 00:00:00

  • Safety and early efficacy of irreversible electroporation for hepatic tumors in proximity to vital structures.

    abstract:INTRODUCTION:Irreversible electroporation (IRE) has shown promise for ablation of lesions in proximity to vital structures in the preclinical setting. This study aims to evaluate the safety and efficacy of IRE for hepatic tumors in the clinical setting. METHODS:An IRB approved prospective registry of patients undergoi...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.23280

    authors: Cannon R,Ellis S,Hayes D,Narayanan G,Martin RC 2nd

    更新日期:2013-04-01 00:00:00

  • Distribution and patterns of lymph nodes metastases and micrometastases in the mesorectum of rectal cancer.

    abstract:BACKGROUND AND OBJECTIVES:Facts buried in the mesorectum remain to be unveiled. This study investigated the number, size, and detailed distribution of lymph nodes metastases and micrometastases within the mesorectum of rectal cancer. METHODS:Thirty-one patients who underwent total mesorectal excision (TME) were treate...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.20826

    authors: Zheng YC,Zhou ZG,Li L,Lei WZ,Deng YL,Chen DY,Liu WP

    更新日期:2007-09-01 00:00:00

  • Gastric cancer molecular classification and adjuvant therapy: Is there a different benefit according to the subtype?

    abstract:BACKGROUND:Gastric cancer (GC) has been defined in distinct molecular subtypes with different therapeutic implications. However, its clinical significance and prognosis regarding standard chemotherapy (CMT) remains unclear. This study aimed to analyze the impact of perioperative or adjuvant treatment among subtypes of ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.25792

    authors: Ramos MFKP,Pereira MA,Amorim LC,de Mello ES,Faraj SF,Ribeiro U,Hoff PMG,Cecconello I,de Castria TB

    更新日期:2020-04-01 00:00:00

  • Radical reoperation for invasive cervical cancer found in simple hysterectomy.

    abstract:OBJECTIVE:To evaluate the patients with invasive cervical cancer found in simple hysterectomy and who were subjected to radical parametrectomy and upper vaginectomy with therapeutic lymphadenectomy. METHODS:Twenty-seven patients who underwent the radical parametrectomy and upper vaginectomy with therapeutic lymphadene...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.20550

    authors: Ayhan A,Otegen U,Guven S,Kucukali T

    更新日期:2006-07-01 00:00:00

  • An inverse dose response of 5-methyl cytidine on multiple primary spontaneous tumors and their regressions in mice.

    abstract::Ten series mice of C3H/ST inbreds with spontaneous tumors have received 5-methyl cytidine (total 500 mice). Graded single doses of (1) 3.86, (2) 2.57, (3) 2.06, (4) 1.54, (5) 1.03, (6) 1.54, (7) 1.03, (8) 0.51, (9) 0.26, and (10) 0.13 mg/injection (three times weekly) were used. In series 1-5 the 5-methyl cytidine was...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930070614

    authors: Strong LC,Matsunaga H

    更新日期:1975-01-01 00:00:00

  • Unusual presentation of carcinoma of the vermiform appendix: a report of two cases.

    abstract::Two unusual presentations of perforated mucoid adenocarcinoma of the appendix are described. One patient presented with a large periappendicular abscess that extended into the gluteal region, the other with a retroperitoneal abscess and abscesses in the right flank and groin. Recognition of the source of the abscess m...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930250409

    authors: Waizbard E,Michowitz M,Baratz M,Papo J,Stavorovsky M

    更新日期:1984-04-01 00:00:00

  • Potential survival benefit of radiofrequency ablation for small solitary intrahepatic cholangiocarcinoma in nonsurgically managed patients: A population-based analysis.

    abstract:BACKGROUND:Little data regarding the selection of nonsurgical therapies for localized intrahepatic cholangiocarcinoma (ICC) are available. METHODS:A cohort of nonsurgically managed patients with American Joint Commission on Cancer clinical stage I/II ICC in the United States from 2004 to 2013 were identified in the Na...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.25736

    authors: Wu L,Tsilimigras DI,Farooq A,Hyer JM,Merath K,Paredes AZ,Mehta R,Sahara K,Shen F,Pawlik TM

    更新日期:2019-12-01 00:00:00

  • When to start an aromatase inhibitor: now or later?

    abstract::Among women who have undergone surgery for breast cancer, the risk of recurrence, especially distant metastases, peaks 1-2 years postsurgery. Recent clinical trial evidence suggests that initial adjuvant therapy with an aromatase inhibitor (AI) can reduce this early risk of recurrence. According to the recently update...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.21801

    authors: Doughty JC

    更新日期:2011-06-01 00:00:00

  • Frequent K-ras mutations and absence of p53 mutations in mucin-producing tumors of the pancreas.

    abstract::Mucin-producing tumors of the pancreas (MPT) are characterized by the production of much mucin and a benign course after surgical treatment. We examined 16 cases of MPT and 20 cases of "common" pancreatic duct cell carcinomas (DCC) in regard to K-ras and p53 mutations. The mutations were detected by constant denaturan...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930550205

    authors: Hoshi T,Imai M,Ogawa K

    更新日期:1994-02-01 00:00:00