Abstract:
BACKGROUND:Identification of peri-operative variables predicting postoperative morbidity may improve postoperative patients' care. We aimed to identify patients' characteristics and operative factors predictive of early (≤ 30-day) and late (≤ 6-month) morbidity in cervical cancer patients undergoing surgery plus external beam radiotherapy (EBRT). METHODS:We studied 45 propensity-matched patient pairs (90 patients) undergoing laparoscopic radical hysterectomy (LRH) plus EBRT vs. abdominal radical hysterectomy (RAH) plus EBRT. Basic descriptive, multivariable and artificial neuronal network analyses (ANN) were used to design predicting models influencing outcomes. RESULTS:Baseline characteristics of the study populations were similar. Patients undergoing LRH experienced lower blood loss (200 (range, 10-700) vs. 400 (range, 100-2000) ml; P < 0.001), shorter length of hospital stay (4 (range, 1-10) vs. 8 (range, 5-52) days; P < 0.001) and similar operative time (235 (± 67.3) vs. 258 (± 70.2) min; P = 0.14) than patients undergoing RAH. We observed that, at multivariate analysis, open approach correlated with overall (OR: 1.2; 95%CI: 1.03-1.46), early (OR: 1.14; 95%CI:0.99-1.3) and late (OR: 1.13; 95%CI: 1.001-1.28) postoperative complications. CONCLUSIONS:Open approach is the main predictor for developing morbidity among cervical cancer patients undergoing radical hysterectomy followed by adjuvant radiotherapy. Laparoscopic surgery enhances peri-operative surgical results and minimizes the occurrence of late complications.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Bogani G,Cromi A,Serati M,Di Naro E,Uccella S,Donadello N,Ghezzi Fdoi
10.1002/jso.23747subject
Has Abstractpub_date
2014-12-01 00:00:00pages
893-8issue
7eissn
0022-4790issn
1096-9098journal_volume
110pub_type
杂志文章abstract::Malignant bowel obstruction (MBO) is a common problem for patients with advanced malignancy, especially colorectal and ovarian cancers. Symptoms include pain, bloating, nausea and vomiting, and inability to eat. Treatment options consist of a wide range of surgical and nonsurgical interventions (medications, endoscopi...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.25451
更新日期:2019-07-01 00:00:00
abstract::Delayed hypersensitivity reaction of 116 consecutive cases of urologic cancers were studied by skin tests. Ninety-one percent of those who were operable or free of diseases at least six months had positive skin reaction. All patients with inoperable or recurrent bladder, kidney, or testis tumor had negative skin react...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930070112
更新日期:1975-01-01 00:00:00
abstract:BACKGROUND:The choice of performing surgery when tumors encroach onto joints remains a challenging and controversial issue. Pre-operative assessment by magnetic resonance imaging (MRI) is of critical importance in dictating surgical management and subsequent functional outcome. METHODS:We examined archival samples fro...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20268
更新日期:2005-09-01 00:00:00
abstract:OBJECTIVE:To determine whether the presence of prostate stem cell antigen (PSCA) mRNA in peripheral blood can predict biochemical recurrence (BCR) after radical prostatectomy in patients with high-risk prostate cancer. METHODS:High-risk disease was defined based on the presence of any one of the following three risk f...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21445
更新日期:2010-02-01 00:00:00
abstract::Diffuse malignant peritoneal mesothelioma (DMPM) has been traditionally regarded as a rapidly lethal disease. Recently, several independent prospective trials have reported improved survival with an intensive loco-regional treatment strategy including cytoreductive surgery (CRS) along with peri-operative intra-periton...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.21055
更新日期:2008-09-15 00:00:00
abstract:BACKGROUND:Locally advanced colon cancer can result in serious clinical conditions unless treated appropriately. The aim of this study was to examine the feasibility of en bloc resection and the significance of depth of invasion by analyzing the outcomes of the procedure in colon cancer invading adjacent organs. METHO...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21165
更新日期:2009-01-01 00:00:00
abstract::Sentinel lymph node (sN) biopsy has gained special attention among surgical and medical oncologists as it represents an accepted technique for detecting occult nodal disease in regional lymph nodes of patients with melanoma and breast cancer. The histopathologic examination of the sN may well predict regional lymph no...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.20031
更新日期:2004-03-01 00:00:00
abstract::Mucin-producing tumors of the pancreas (MPT) are characterized by the production of much mucin and a benign course after surgical treatment. We examined 16 cases of MPT and 20 cases of "common" pancreatic duct cell carcinomas (DCC) in regard to K-ras and p53 mutations. The mutations were detected by constant denaturan...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930550205
更新日期:1994-02-01 00:00:00
abstract:BACKGROUND:The objective of the current study was to define the impact of albumin-bilirubin (ALBI) grade on short- as well as long-term outcomes among patients with intrahepatic cholangiocarcinoma (ICC). METHODS:Patients who underwent hepatectomy for ICC between 1990 and 2016 were identified using an international mul...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,多中心研究
doi:10.1002/jso.25486
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Transcription factor Snail1 is a key inducer of epithelial-mesenchymal transition (EMT), a biological process implicated in the cancer progression and metastasis. The aim of the study was to investigate Snail1 expression in DCIS found on breast biopsy and assess its predictive value for the fi...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24708
更新日期:2017-11-01 00:00:00
abstract::A case of extramammary Paget's disease is reported. The distinguishing features of the case are: (1) localization of the primary lesion to the scrotum, (2) development of metastases in the absence of a recognizable underlying carcinoma, and (3) response of the systemic disease to a combination of radiation therapy and...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930380111
更新日期:1988-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Adjuvant radiotherapy for node positive breast cancer postmastectomy has been recommended by two previously published randomized controlled trials (RCT). The local-regional recurrence rates in the control arms, however, were considered by some critics to be excessive (> 25% at 10 years). Inadeq...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.1114
更新日期:2001-09-01 00:00:00
abstract:BACKGROUND:CD109, a TGF-β co-receptor, is reported to be preferentially expressed during the early stages of tumorigenesis in several carcinoma types. Myxofibrosarcoma is one of the most common soft-tissue sarcomas found in elderly patients. This study aimed to elucidate the impact of CD109 expression in myxofibrosarco...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23934
更新日期:2015-06-01 00:00:00
abstract::This article reviews immediate and delayed breast reconstruction with prosthetic implants, and the effect of irradiation therapy. Despite widespread use of breast conserving surgery for early breast cancer, many breast cancer patients still undergo mastectomy. Some of these patients choose breast reconstruction. Over ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.20484
更新日期:2006-11-01 00:00:00
abstract:BACKGROUND:At present, the majority of outcome studies of survival of hepatocellular carcinoma (HCC) post-liver resection (post-LR) present actuarial survival data, which often results in overestimation of survival. We sought to evaluate the actual 10-year survival post-LR for HCC and identify variables that are associ...
journal_title:Journal of surgical oncology
pub_type: 临床试验,杂志文章
doi:10.1002/jso.26259
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The therapeutic role of systematic lymph node dissection (LND) remains unclear in advanced epithelial ovarian cancer (EOC), especially during interval debulking surgery (IDS) performed after neoadjuvant chemotherapy (NAC). We analyzed the therapeutic and prognostic roles of systematic LND in ad...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24669
更新日期:2017-09-01 00:00:00
abstract::An unusual case of Merkel cell carcinoma of the lower lip with metastasis to the submental nodes is presented. Clinical similarities and the histopathologic and prognostic differences between this tumor and basal or squamous cell carcinomas of the head and neck area are discussed and the current thoughts for treatment...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930370212
更新日期:1988-02-01 00:00:00
abstract::A prospective randomized phase III trial was carried out at Songklanagarind Hospital from August 1988 to December 1990. The objectives of the study were to evaluate the effect of chemotherapy regimen in squamous cell carcinoma of the esophagus and to determine whether induction chemotherapy improves symptom-free perio...
journal_title:Journal of surgical oncology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/jso.2930560314
更新日期:1994-07-01 00:00:00
abstract:BACKGROUND:The role of postmastectomy radiation therapy (PMRT) after neoadjuvant chemotherapy (NAC) and mastectomy is unclear, especially in patients that have post-treatment tumor negative axillary nodes (ypN0). METHODS:The National Cancer Data Base was used to identify women that had PMRT after NAC and mastectomy fo...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24551
更新日期:2017-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Gastric cancer recurrence after curative surgery remains high. Although no preoperative marker of gastric cancer progression after radical gastrectomy exists, recent studies suggest that C-reactive protein (CRP) is associated with cancer progression. Our study evaluated the significance of pre...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.22129
更新日期:2012-03-15 00:00:00
abstract::Distribution of Leu-7+ cells in cancer tissues and regional lymph nodes was immunohistochemically examined to estimate the role of NK cells in colorectal cancer patients. Leu-7+ cells were rarely observed both in the primary and distant metastatic lesions, but the number of these cells was large in the germinal center...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930450406
更新日期:1990-12-01 00:00:00
abstract::Thirty-eight cases of advanced upper gastrointestinal cancer were assessed for their immune status prior to any form of therapy. Cell-mediated immunity, as tested by absolute lymphocyte count, T-cell count and delayed cutaneous hypersensitivity reactions to purified protein derivative and phytohemagglutinin showed sev...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930290113
更新日期:1985-05-01 00:00:00
abstract:INTRODUCTION:The need for regional lymphadenectomy for treating appendiceal neuroendocrine tumors (A-NET) is determined by the risk of nodal metastasis. Current guidelines for A-NET are solely based on tumor size. Methods Patients with A-NET from 1988 to 2012 were identified from the SEER registry. The depth of invasio...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24714
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Stages II and III rectal tumors are known as locally advanced rectal cancer (LARC) because they are characterized by a high incidence of local and distant relapses and a low probability of long-term survival. Adjuvant treatments have been advocated to ameliorate overall survival (OS), local re...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/1096-9098(200005)74:1<2::aid-jso2>3.0.co;2
更新日期:2000-05-01 00:00:00
abstract::Intrapancreatic extension of pancreatic duct cell carcinoma in 19 resectable cases was evaluated by both hematoxylin and eosin (H&E) staining and quick immunostaining using antibodies against cancer-associated antigens--e.g., CA19-9, DUPAN 2, and CEA--on the intraoperative frozen-section biopsy during the course of la...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930400105
更新日期:1989-01-01 00:00:00
abstract::A case of spine metastasis of basal cell carcinoma and review of the literature are presented. The treatment approach is discussed. ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930250109
更新日期:1984-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Lymph node involvement is common in thyroid cancer, but the system of staging does not consider the histological features of lymph node metastases. We conducted a meta-analysis to investigate the prognostic role of extranodal extension (ENE) in thyroid cancer patients. METHODS:We ran PubMed a...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,meta分析,评审
doi:10.1002/jso.24070
更新日期:2015-12-01 00:00:00
abstract::The clinicopathologic features of 118 granular cell tumors (GCT) encountered at two affiliated hospitals were reviewed. A total of 110 patients were affected over this 32-year period of study (71 men, 39 women), and in 5% GCT were multiple. Patients ranged in age from 16 to 58 years (average 32 years) and were symptom...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930130405
更新日期:1980-01-01 00:00:00
abstract::The records of 130 patients with soft tissue and bone sarcomas were retrospectively analyzed to identify the subgroups of patients that would benefit from tomographic studies for pulmonary metastasis. Sixty-six of 96 patients with a normal conventional chest roentgenogram (CXR) had tomography to diagnose pulmonary met...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930380414
更新日期:1988-08-01 00:00:00
abstract:BACKGROUND:The object of the current study was to review the outcomes of hepatic resection for hepatocellular carcinoma (HCC) ≥ 10 cm. METHODS:Between 1995 and 2007, fifty-three patients with HCC ≥ 10 cm underwent hepatic resection, and clinical data were compared to those of patients with non-surgical treatment (n = ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21931
更新日期:2011-09-01 00:00:00