Abstract:
BACKGROUND:Pulmonary metastasectomy (PM) for metastatic sarcoma can result in long-term survival. The purpose of this study was to describe factors associated with survival in a series of patients undergoing PM for metastatic sarcoma. METHODS:We reviewed all patients undergoing PM for metastatic sarcoma over a 12-year period (2000-2012). Multivariate analyses were used to identify factors associated with outcomes. Survival was calculated with Kaplan-Meier and Cox proportional hazard models. RESULTS:A total of 120 patients underwent PM with a median follow-up was 48 months. Among 81 (85%) patients who presented with local disease, the median disease free interval (DFI) was 13 months and median overall survival (OS) was 48 months. Fourteen patients (15%) had synchronous metastasis with a median OS of 21 months. On multivariate analysis, synchronous metastasis (P = 0.005), older age (P = 0.02), and number of lung lesions (P = 0.003) were associated with poor survival. The median OS of patients with a DFI ≥12 versus <12 months following primary resection was 93 and 43 months (P = 0.004). CONCLUSION:While patients with a DFI >12 months have the best OS following PM, patients with a DFI <12 months also have excellent outcomes as compared to systemic therapy and should be considered for PM.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Dossett LA,Toloza EM,Fontaine J,Robinson LA,Reed D,Druta M,Letson DG,Zager JS,Gonzalez RJdoi
10.1002/jso.23961subject
Has Abstractpub_date
2015-07-01 00:00:00pages
103-6issue
1eissn
0022-4790issn
1096-9098journal_volume
112pub_type
杂志文章abstract:BACKGROUND:Extrapleural pneumonectomy for malignant pleural mesothelioma is considered an aggressive procedure, but symptomatic and quality of life changes are unknown. METHODS:Between 1997 and 2004, 16 consecutive patients underwent extrapleural pneumonectomy for mesothelioma followed by chemo-radiotherapy. Tumor-rel...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21261
更新日期:2009-09-01 00:00:00
abstract::The majority of patients with pulmonary metastases from primary soft tissue sarcomas have peripheral lesions that can be removed by wedge excision. A subset of these patients, however, present with, or develop, clinically significant endobronchial metastases. These patients require a preoperative evaluation that inclu...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930320305
更新日期:1986-07-01 00:00:00
abstract::Remote access approaches for thyroid surgery using surgical incisions placed outside the neck, including the axillary, chest and the retro-auricular region have gained interest due to the social stigmatization of young females with a visible neck scar. These novel approaches have been reported to be safe and feasible ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.23955
更新日期:2015-09-01 00:00:00
abstract::The realm of cancer chemotherapy is complex and often conflicting. The massive use of cytotoxic agents during the past 25 years has now reached a point where major decisions have to be made. The respective roles of regional techniques, systemic therapy for metastatic disease and adjuvant cytotoxic chemotherapy, all ne...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930300411
更新日期:1985-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The volume-outcome relationship is well recognized. We sought to investigate this relationship in retroperitoneal sarcoma (RPS) surgery. METHODS:Non-metastatic RPS cases from 2004 to 2014 in the National Cancer Database were analyzed. Hospitals in the top 10th percentile for volume were defin...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24710
更新日期:2017-11-01 00:00:00
abstract::A case of renal cell carcinoma arising in a horseshoe kidney and presenting with a pathologic fracture of humerus is reported. Relevant literature is discussed. ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930260116
更新日期:1984-05-01 00:00:00
abstract:BACKGROUND:Multiple free tissue transfer from the same donor site is not well described for microsurgical head and neck reconstruction. METHODS:Between (8/2011 and 11/2012), 103 patients received 103 free ALT flaps for head and neck reconstruction; flaps were called first-time ALT flaps. Intra-operative findings were ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24558
更新日期:2017-03-01 00:00:00
abstract::The journey of gastrinomas had its beginnings in 1955 when Zollinger and Ellison published their seminal paper (Zollinger and Ellison, Ann Surg 1955; 142: 709-723). The evolution of the diagnosis and management of this syndrome has paralleled many important advances in medicine, including the development of various di...
journal_title:Journal of surgical oncology
pub_type: 历史文章,杂志文章,评审
doi:10.1002/jso.21359
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The effects of isolated metastatic node dissection in the para-aortic region have not been established in colorectal cancer (CRC). The authors undertook to evaluate the role of para-aortic lymph node (PALN) dissection in CRC with isolated PALN metastasis. METHODS:Between January 1993 and Marc...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21421
更新日期:2010-01-01 00:00:00
abstract::We report a patient with a large apocrine hidrocystoma. These tumors are almost always under 10 mm in diameter. In this 40-year-old man the tumor measured 20 mm. Apocrine hidrocystoma must be considered when evaluating a patient with a large cystic lesion of the face. Surgical management is similar to that of other be...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930270304
更新日期:1984-11-01 00:00:00
abstract:BACKGROUND:Interleukin-6 (IL-6) is closely associated with tumor progression. Whether it can predict postoperative prognosis of patients with T2 gallbladder cancer (GBC) remains controversial. METHODS:We retrospectively collected the medical records of 125 patients with T2 GBC. Then, we analyzed the association betwee...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25085
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Recent studies have disclosed the presence of somatic mutations in the epidermal growth factor receptor (EGFR) gene in non-small cell lung cancers (NSCLC), and susceptibility to the EGFR tyrosine kinase inhibitor (gefitinib) was determined by the presence of mutations in the kinase domain of t...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20426
更新日期:2006-01-01 00:00:00
abstract::Recently we resected and reconstructed the sternum in two female patients with thyroid carcinoma metastatic to the sternum. Histological diagnosis of the metastatic lesion was follicular carcinoma in the first case and papillary carcinoma in the second case. Reconstruction of the sternum was accomplished by using an a...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930600413
更新日期:1995-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Preoperative positivity of serum tumor markers has been reported to be a prognostic factor in several neoplasms. The aim of this longitudinal study was to evaluate the correlation between CEA, CA 19-9, and CA 72-4 preoperative serum levels and the site of recurrence after curative surgery for ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.1163
更新日期:2001-12-01 00:00:00
abstract:BACKGROUND:Gastric cancer (GC) has been defined in distinct molecular subtypes with different therapeutic implications. However, its clinical significance and prognosis regarding standard chemotherapy (CMT) remains unclear. This study aimed to analyze the impact of perioperative or adjuvant treatment among subtypes of ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25792
更新日期:2020-04-01 00:00:00
abstract::We investigated the incidence of thyroid nodules in female uremic patients on maintenance hemodialysis using a high-frequency sonographic scanner. In 47 (21.0%) of the 224 female normal controls and 33 (55.0%) of the 60 female patients, thyroid nodules were detected. The difference in these incidences between controls...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930540405
更新日期:1993-12-01 00:00:00
abstract::The clinical evidence suggests that the steroid hormones may influence the biologic course of tumors of soft tissue. In an attempt to characterize the possible steroid hormone dependency of soft tissue, we studied the incidence and distribution of cytosolic receptors for the steroid hormones in benign and malignant tu...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930280203
更新日期:1985-02-01 00:00:00
abstract::Several months (an average of 12.86 months) after perineal needling of the cancerous prostate for the purpose of obtaining tissue for biopsy, a tumor nodule becomes clinically evident in the subcutaneous tissue of the perineum, at the site of the needling in 0.34% of the cases. This nodule presents the same histologic...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.2930350309
更新日期:1987-07-01 00:00:00
abstract::Intra-abdominal visceral sarcomas are a rare group of mesenchymal tumors that require the use of distinct surgical principles and a multidisciplinary approach in order to optimize treatment. Surgery remains the only potentially curative treatment. Management and outcomes vary for the different sarcomas arising from vi...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23803
更新日期:2015-04-01 00:00:00
abstract::The clinicopathologic features of a case of malignant Brenner tumor with bilateral ovarian involvement are described. The tumor was apparently confined within the ovaries at initial laparotomy. However, multiple skeletal metastases developed 4 months later and the patient died of the disease 6 months after diagnosis. ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930260312
更新日期:1984-07-01 00:00:00
abstract::A primary retroperitoneal dermoid cyst (benign cystic teratoma) is described in a 64-year-old male, who died postoperatively of a leaking grafted abdominal aortic aneurysm. The asymptomatic tumor, measuring 12 cm in greatest diameter, showed an extensive sclerosing lipogranulomatous reaction in its wall and wide-sprea...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930140102
更新日期:1980-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The propeller flap is a reliable option for reconstruction after soft tissue sarcoma resection. However, some parts of the resection margin may move away from its original position during flap rotation and thus can be excluded from the clinical target volume of adjuvant radiotherapy. This stud...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.26076
更新日期:2020-06-28 00:00:00
abstract::Three patients with unresectable malignant retroperitoneal tumors that invaded and perforated the distal duodenum presented with sepsis unresponsive to antibiotics. A technique of proximal side-to-side duodenojejunostomy with stapled occlusion of the distal duodenum resulted in successful diversion and immediate resol...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930260410
更新日期:1984-08-01 00:00:00
abstract::Metastatic colorectal cancer (mCRC) continues to show poor outcomes, with many patients exhausting effective standard-of-care therapy. To explore the current landscape of clinical trials for mCRC, we reviewed over 600 clinical trials that are currently ongoing for mCRC patients. Immunotherapeutic agents form approxima...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.25441
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Sentinel node (SN) biopsy is a new standard of care for axillary node staging in patients with early-stage, clinically node-negative breast cancer. A second operation can be avoided when the results are available intraoperatively. However, there is no standard intraoperative method for SN asse...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.20067
更新日期:2004-06-01 00:00:00
abstract::Development of a carcinoma in the pancreas of a young man who had five years previously undergone intensive radiotherapy and subsequent chemotherapy for treatment of a lymphoma suggests that induction of the second neoplasm occurred as the result of the therapy of the first. While definite proof of causality is lackin...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930080603
更新日期:1976-01-01 00:00:00
abstract:BACKGROUND:Gastric cancer (GC) in Israel remains incompletely characterized. The aim of this study was to define the clinical and pathological characteristics of GC in Israel and to compare them to the general Western population. PATIENTS AND METHODS:This is a retrospective analysis of 461 consecutive GC patients trea...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.22078
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND:The aim of this study was to determine the effect of tumor encapsulation of hepatocellular carcinoma (HCC) on long-term survival. METHODS:A retrospective review of 1,240 patients who underwent hepatectomy from January 1993 to June 2005 was conducted. There were 891 patients with tumor encapsulation (EC type...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.22060
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:ERCP prior to pancreaticoduodenectomy is unnecessary in select patients. When performed, it should be in conjunction with endoscopic ultrasound (EUS) to increase diagnostic sensitivity and allow for metal stent placement. The aim of this study was to determine differences in endoscopic practic...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24191
更新日期:2016-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Prolonged air leaks (PAL) are the most frequent complication after lobectomy for non-small cell lung cancer, even in case of minimally invasive approaches. We developed a novel score to identify high-risk patients for PAL during minimally invasive lobectomy. METHODS:A dedicated database was c...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25289
更新日期:2018-12-01 00:00:00