Heterotopic ossification in rectal cancer: Rare finding with a novel proposed mechanism.

Abstract:

:The rare finding of heterotopic ossification in a case of primary rectal adenocarcinoma is described along with a review of the literature. Immunohistochemistry for a bone morphogenic protein (BMP-2) and fibroblast growth factor (FGF-2), both of which induce and stimulate bone formation, was performed and revealed overexpression of BMP-2 by the tumor cells, elucidating a possible mechanism which up to now had been based merely on speculation.

journal_name

J Surg Oncol

authors

Kypson AP,Morphew E,Jones R,Gottfried MR,Seigler HF

doi

10.1002/jso.10181

subject

Has Abstract

pub_date

2003-02-01 00:00:00

pages

132-6; disccussion 137

issue

2

eissn

0022-4790

issn

1096-9098

journal_volume

82

pub_type

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