Abstract:
OBJECTIVE:To develop a classification system using imaging features to interpret breast non-mass lesions (NMLs) detected on US and to stratify their cancer risk. METHODS:This retrospective study included 715 patients with 715 breast NMLs detected on breast US from 2012 to 2016. Each patient underwent mammography at the time of diagnosis. Radiologists assessed US and mammographic features and final BI-RADS categories. Multivariable logistic regression was used to find imaging features associated with malignancy in a development dataset (n = 460). A system to classify BI-RADS categories (3 to 5) was developed based on the odds ratios (ORs) of imaging features significantly associated with malignancy and validated in a distinct validation dataset (n = 255). RESULTS:Among 715 NMLs, 385 (53.8%) were benign and 330 (46.2%) were malignant. In the development dataset, the following B-mode US features were associated with malignancy (all p < 0.001): segmental distribution (OR = 3.03; 95% confidence interval [CI], 1.50-6.15), associated calcifications (OR = 4.26; 95% CI, 1.62-11.18), abnormal ductal change (OR = 4.91; 95% CI, 2.07-11.68), and posterior shadowing (OR = 20.20; 95% CI, 6.46-63.23). The following mammographic features were also associated with malignancy (all p < 0.001): calcifications (OR = 7.98; 95% CI, 3.06-20.81) and focal asymmetry (OR = 4.75; 95% CI, 1.90-11.88). In the validation dataset, our classification system using US and mammography showed a higher area under the curve (0.951-0.956) compared to when it was not applied (0.908-0911) to predict malignancy with BI-RADS categories (p < 0.05). CONCLUSION:Our classification system which incorporates US and mammographic features of breast NMLs can help interpret and manage all NMLs detected on breast US by stratifying cancer risk according to BI-RADS categories. KEY POINTS:• When diagnosing breast NMLs detected on US, suspicious US features are segmental distribution, associated abnormal ductal change, calcifications, and posterior shadowing within or around the NML on B-mode US, while a probably benign US feature is the presence of multiple small cysts. • Corresponding suspicious mammographic features of breast NMLs detected on US are associated calcifications and focal asymmetry. • Our classification system which incorporates US features with and without mammography can potentially be used to interpret and manage any NMLs detected on breast US in clinical practice.
journal_name
Eur Radioljournal_title
European radiologyauthors
Park KW,Park S,Shon I,Kim MJ,Han BK,Ko EY,Ko ES,Shin JH,Kwon MR,Choi JSdoi
10.1007/s00330-020-07168-ysubject
Has Abstractpub_date
2020-09-04 00:00:00eissn
0938-7994issn
1432-1084pii
10.1007/s00330-020-07168-ypub_type
杂志文章abstract:OBJECTIVES:To determine the integrative value of clinical, hematological, and computed tomography (CT) radiomic features in survival prediction for locally advanced non-small cell lung cancer (LA-NSCLC) patients. METHODS:Radiomic features and clinical and hematological features of 118 LA-NSCLC cases were firstly extra...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-018-5949-2
更新日期:2019-06-01 00:00:00
abstract:OBJECTIVE:Medical imaging acquired for clinical purposes can have several legitimate secondary uses in research projects and teaching libraries. No commonly accepted solution for anonymising these images exists because the amount of personal data that should be preserved varies case by case. Our objective is to provide...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-010-1745-3
更新日期:2010-08-01 00:00:00
abstract::The purpose of the study was to evaluate a semiautomatic analysis tool for assessing global left ventricular myocardial function with multislice computed tomography (MSCT). We examined 33 patients with MSCT using 16x0.5 mm detector collimation and magnetic resonance imaging (MRI) on a 1.5-T scanner. MSCT data were ana...
journal_title:European radiology
pub_type: 临床试验,杂志文章
doi:10.1007/s00330-005-2817-7
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVES:To describe a randomized controlled trial (RCT) of digital breast tomosynthesis including synthesized two-dimensional mammograms (DBT) versus digital mammography (DM) in a population-based screening program for breast cancer and to compare selected secondary screening outcomes for the two techniques. METHOD...
journal_title:European radiology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s00330-018-5690-x
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVES:To determine the sensitivity and positive predictive value (PPV) of gadobenate-enhanced MR imaging for the detection of liver metastases. METHODS:This systematic review and meta-analysis was conducted according to PRISMA guidelines. A comprehensive search (EMBASE, PubMed) was performed to identify relevant ...
journal_title:European radiology
pub_type: 杂志文章,meta分析
doi:10.1007/s00330-019-06110-1
更新日期:2019-10-01 00:00:00
abstract::In paediatric radiology it has been recognised that children have a higher risk of developing cancer from the irradiation than adults (two to three times); therefore, increased attention has been directed towards the dose to the patient. In this study the effect on patient dose and image quality in replacing the expos...
journal_title:European radiology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00330-003-2144-9
更新日期:2004-04-01 00:00:00
abstract::The purpose of this study was to assess the performance of a new motion correction algorithm. Twenty-five dynamic MR mammography (MRM) data sets and 25 contrast-enhanced three-dimensional peripheral MR angiographic (MRA) data sets which were affected by patient motion of varying severeness were selected retrospectivel...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-006-0224-3
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVES:Chronic obstructive pulmonary disease (COPD) is characterized by variable contributions of emphysema and airway disease on computed tomography (CT), and still little is known on their temporal evolution. We hypothesized that quantitative CT (QCT) is able to detect short-time changes in a cohort of patients w...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-019-06577-y
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:To develop and validate a decision support tool for mammographic mass lesions based on a standardized descriptor terminology (BI-RADS lexicon) to reduce variability of practice. MATERIALS AND METHODS:We used separate training data (1,276 lesions, 138 malignant) and validation data (1,177 lesions, 175 malignant...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-014-3570-6
更新日期:2015-06-01 00:00:00
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journal_title:European radiology
pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07037-8
更新日期:2021-01-01 00:00:00
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journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-004-2352-y
更新日期:2005-01-01 00:00:00
abstract::This paper evaluates the management of 31 patients with bile leaks identified over a 7-year period. Leaks complicated cholecystectomy in 19 patients (11 laparoscopic, 8 open), interventional procedures in 10 (including surgery in 1), trauma in one and was spontaneous in one case. Confirmation of the diagnosis typicall...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050595
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVES:To determine lumbar intervertebral disc properties with shear wave elastography in adolescent idiopathic scoliotic (AIS) patients before and after surgery, and compare them with asymptomatic controls. METHODS:Twenty-five severe AIS patients with an indication for fusion surgery (15 ± 1.5 years old, the Cobb...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-019-06563-4
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journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-007-0816-6
更新日期:2008-04-01 00:00:00
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journal_title:European radiology
pub_type: 杂志文章,meta分析
doi:10.1007/s00330-006-0312-4
更新日期:2006-12-01 00:00:00
abstract::The original version of this article, published on 12 August 2019, unfortunately contained a mistake. The funding note was incorrect; the correct funding note is given below. ...
journal_title:European radiology
pub_type: 已发布勘误
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更新日期:2020-09-01 00:00:00
abstract:OBJECTIVES:To validate a visual rating scale of frontal atrophy with quantitative imaging and study its association with clinical status, APOE ε4, CSF biomarkers, and cognition. METHODS:The AddNeuroMed and ADNI cohorts were combined giving a total of 329 healthy controls, 421 mild cognitive impairment patients, and 28...
journal_title:European radiology
pub_type: 杂志文章
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journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-002-1640-7
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abstract::A "quadraphasic" imaging technique is described for imaging malignancies of the abdomen (liver, kidneys and pancreas). With this technique images are acquired during four different phases relative to the administration of contrast agent: pre-contrast (baseline), during the capillary (arterial, pre-sinusoidal) phase, d...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/pl00006899
更新日期:1997-01-01 00:00:00
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pub_type: 杂志文章,评审
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journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-010-2013-2
更新日期:2011-05-01 00:00:00
abstract::Our purpose was to assess image quality and interpretation problems of two-dimensional (2D) coronary MR angiograms. The coronary arteries of 27 subjects (12 normal volunteers and 15 patients) were evaluated with 2D coronary MR angiography (MRA). Coronary MRA was performed with a fat-suppressed electrocardiographically...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/BF00180601
更新日期:1996-01-01 00:00:00
abstract::The aim of this study was to demonstrate that dose reduction and constant image quality can be achieved by adjusting X-ray dose to patient size. To establish the relation between patient size, image quality and dose we scanned 19 patients with reduced dose. Image noise was measured. Four radiologists scored image qual...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300101039
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVES:Accurately predicting the WHO classification of thymomas is urgently needed to optimize individualized therapeutic strategies. We aimed to develop and validate a combined radiomics nomogram for personalized prediction of histologic subtypes in patients with thymomas. METHODS:A total of 182 thymoma patients ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07074-3
更新日期:2021-01-01 00:00:00
abstract::Positron emission tomography (PET) is a powerful molecular imaging technique for the human body-imaging applications currently available. As altered glucose metabolism is characteristic for many malignancies, FDG-PET is mostly used in oncology for staging and therapy control. Although PET is a sensitive tool for detec...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-005-0088-y
更新日期:2006-05-01 00:00:00
abstract::The aim of this study was to develop an endorectal MRI strategy for prostatic cancer. We evaluated the MR images from 44 consecutive prostatic cancer patients treated by radical prostatectomy. Each sequence from every examination was assessed separately with a specific tumor map drawn. Tumor localization, capsular pen...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300000598
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVES:This prospective trial was performed to verify whether microwave ablation (MWA) in combination with chemotherapy could provide superior survival benefit compared with chemotherapy alone. MATERIALS AND METHODS:From March 1, 2015, to June 20, 2017, treatment-naïve patients with pathologically verified advance...
journal_title:European radiology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s00330-019-06613-x
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVE:This tertiary care experience examines the utility of magnetic resonance neurography (MRN) in the management of peripheral trigeminal neuropathies. MATERIALS AND METHODS:Seventeen patients with clinically suspected peripheral trigeminal neuropathies (inferior alveolar nerve and lingual nerve) were imaged uni...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-015-4182-5
更新日期:2016-10-01 00:00:00