The clinical value of a negative multi-detector computed tomographic angiography in patients suspected of coronary artery disease: A meta-analysis.


:The aim of this meta-analysis was to calculate the sensitivity of contrast-enhanced multi-detector computed tomography (MDCT) compared with coronary angiography (CAG) in incident patients suspected of coronary artery disease (CAD). We searched PubMed, Embase, bibliographies of original papers and reviews to identify original papers including > or =20 patients. Two independent reviewers selected papers and judged eligible papers on quality. Heterogeneity was assessed and homogeneous subgroups were pooled. Of the 15 included studies, ten provided moderately homogeneous patient-based analyses with absolute diagnostic numbers (n = 630 patients). Pooled sensitivity was 89% (95% confidence interval: 85-92%). Scanners with 16 detectors (n = 4) had higher sensitivities (pooled sensitivity: 91%) than four-detector scanners (n = 6; pooling not possible due to heterogeneity). Seven studies reported sensitivity for a proximal stenosis, but different definitions were used making pooling impossible; sensitivities ranged from 75 to 100%. The sensitivity of four- and 16-detector MDCT is not sufficient to rule out any stenosis in patients suspected of CAD. No conclusions can be drawn with respect to the sensitivity for clinically relevant or proximal stenoses.


Eur Radiol


European radiology


van der Zaag-Loonen HJ,Dikkers R,de Bock GH,Oudkerk M




Has Abstract


2006-12-01 00:00:00












  • Sonographic findings in stress fractures of the lower limb: preliminary findings.

    abstract::Stress fractures are common injuries frequently overlooked on first radiographs, especially in the early course. The gold standard for accurate diagnosis is MRI and scintigraphy. We report six cases of stress fractures of the lower limb diagnosed with sonography and describe typical sonographic features. ...

    journal_title:European radiology

    pub_type: 杂志文章


    authors: Bodner G,Stöckl B,Fierlinger A,Schocke M,Bernathova M

    更新日期:2005-02-01 00:00:00

  • A radiogenomics signature for predicting the clinical outcome of bladder urothelial carcinoma.

    abstract:OBJECTIVES:To determine the integrative value of contrast-enhanced computed tomography (CECT), transcriptomics data and clinicopathological data for predicting the survival of bladder urothelial carcinoma (BLCA) patients. METHODS:RNA sequencing data, radiomics features and clinical parameters of 62 BLCA patients were ...

    journal_title:European radiology

    pub_type: 杂志文章


    authors: Lin P,Wen DY,Chen L,Li X,Li SH,Yan HB,He RQ,Chen G,He Y,Yang H

    更新日期:2020-01-01 00:00:00

  • Multisegmental pneumatocysts of the lumbar spine mimic osteolytic lesions.

    abstract::Circumscribed radiolucencies within the vertebral bones can be due to a variety of changes including benign and malignant tumours or tumour-like lesions. Radiolucencies due to degenerative intraosseous pneumatocyst are very uncommon but have to be taken into the differential diagnosis in well-circumscribed lytic lesio...

    journal_title:European radiology

    pub_type: 杂志文章


    authors: Steingruber IE,Bach CM,Wimmer C,Nogler M,Buchberger W

    更新日期:2001-01-01 00:00:00

  • Grading of uterine cervical cancer by using the ADC difference value and its correlation with microvascular density and vascular endothelial growth factor.

    abstract:OBJECTIVE:To investigate the application value of the ADC(difference) value in evaluating the pathological grade of uterine cervical cancer and to analyse the correlations among microvascular density (MVD), vascular endothelial growth factor (VEGF) expression and maximum ADC(difference) value. METHODS:Fifty-six patien...

    journal_title:European radiology

    pub_type: 杂志文章


    authors: Liu Y,Ye Z,Sun H,Bai R

    更新日期:2013-03-01 00:00:00

  • Developmental nasal midline masses in children: neuroradiological evaluation.

    abstract::Developmental nasal midline masses in children are rare lesions. Neuroimaging is essential to characterise these lesions, to determine the exact location of the lesion and most importantly to exclude a possible intracranial extension or connection. Our objective was to evaluate CT and MRI in the diagnosis of developme...

    journal_title:European radiology

    pub_type: 杂志文章


    authors: Huisman TA,Schneider JF,Kellenberger CJ,Martin-Fiori E,Willi UV,Holzmann D

    更新日期:2004-02-01 00:00:00

  • Cystic lymphangioma of the spleen: US-CT-MRI correlation.

    abstract::A case of a surgically confirmed cystic lymphangioma of the spleen is presented. Preoperative imaging consisted of US, contrast-enhanced CT and MRI, all showing a multiloculated lesion with small cystic cavities divided by thin septa, corresponding to dilated lymphatic spaces. Preoperative studies correlated well with...

    journal_title:European radiology

    pub_type: 杂志文章


    authors: Bezzi M,Spinelli A,Pierleoni M,Andreoli G

    更新日期:2001-01-01 00:00:00

  • MR liver imaging with Gd-EOB-DTPA: a delay time of 10 minutes is sufficient for lesion characterisation.

    abstract:OBJECTIVES:To assess whether, in patients with normal liver function, a hepatobiliary delay time of 10 min after Gd-EOB-DTPA injection is sufficient for lesion characterisation. METHODS:In 42 consecutive patients with suspected focal liver lesions, dynamic MRI was performed after intravenous Gd-EOB-DTPA, followed by h...

    journal_title:European radiology

    pub_type: 杂志文章


    authors: van Kessel CS,Veldhuis WB,van den Bosch MA,van Leeuwen MS

    更新日期:2012-10-01 00:00:00

  • Differentiation between primary CNS lymphoma and glioblastoma: qualitative and quantitative analysis using arterial spin labeling MR imaging.

    abstract:OBJECTIVES:To evaluate the diagnostic performance of arterial spin labelling perfusion weighted images (ASL-PWIs) to differentiate primary CNS lymphoma (PCNSL) from glioblastoma (GBM). METHODS:ASL-PWIs of pathologically confirmed PCNSL (n = 21) or GBM (n = 93) were analysed. For qualitative analysis, tumours were visu...

    journal_title:European radiology

    pub_type: 杂志文章


    authors: You SH,Yun TJ,Choi HJ,Yoo RE,Kang KM,Choi SH,Kim JH,Sohn CH

    更新日期:2018-09-01 00:00:00

  • Contrast-enhanced computed tomographic colonography in the follow-up of colorectal cancer patients: a feasibility study.

    abstract::The aim of our study was to assess whether contrast-enhanced CT colonography is a feasible alternative to both conventional colonoscopy and liver ultrasonography in the follow-up program of colorectal cancer patients. Thirty-five patients, surgically treated for colorectal cancer, underwent a follow-up program that in...

    journal_title:European radiology

    pub_type: 杂志文章


    authors: Laghi A,Iannaccone R,Bria E,Carbone I,Trasatti L,Piacentini F,Lauro S,Vecchione A,Passariello R

    更新日期:2003-04-01 00:00:00

  • Semi-quantitative visual assessment of hepatic tumor burden can reliably predict survival in neuroendocrine liver metastases treated with transarterial chemoembolization.

    abstract:OBJECTIVES:To evaluate the accuracy and reproducibility of semi-quantitative visual assessment of hepatic tumor burden (HTB) on MRI and to investigate its prognostic value in predicting overall survival (OS) in neuroendocrine liver metastases (NELMs) treated with transarterial chemoembolization (TACE). METHODS:Three i...

    journal_title:European radiology

    pub_type: 杂志文章


    authors: Luo Y,Ameli S,Pandey A,Khoshpouri P,Ghasabeh MA,Pandey P,Li Z,Hu D,Kamel IR

    更新日期:2019-11-01 00:00:00

  • Short tau inversion recovery and proton density-weighted fat suppressed sequences for the evaluation of osteoarthritis of the knee with a 1.0 T dedicated extremity MRI: development of a time-efficient sequence protocol.

    abstract::Aim of this study was to develop a time-efficient sequence protocol for a 1.0 T dedicated MR system to be used for whole-organ scoring of osteoarthritis (OA). Thirty-four knees were examined using a protocol that included fat suppressed fast spin echo proton density weighted sequences (PDFS) in three planes plus a cor...

    journal_title:European radiology

    pub_type: 杂志文章,多中心研究


    authors: Roemer FW,Guermazi A,Lynch JA,Peterfy CG,Nevitt MC,Webb N,Li J,Mohr A,Genant HK,Felson DT

    更新日期:2005-05-01 00:00:00

  • Validation of the Ottawa knee rules in an emergency teaching centre.

    abstract::Our objective was to determine the value of the Ottawa knee rules when applied by users with different levels of clinical training. We used a prospective patient survey by the medical students and surgery residents of a European university trauma centre. The study group consisted of 261 eligible patients who presented...

    journal_title:European radiology

    pub_type: 杂志文章


    authors: Ketelslegers E,Collard X,Vande Berg B,Danse E,El-Gariani A,Poilvache P,Maldague B

    更新日期:2002-05-01 00:00:00

  • Non-invasive quantification of pancreatic exocrine function using secretin-stimulated MRCP.

    abstract::Our objective was to quantify water volume using magnetic resonance cholangiopancreatography (MRCP) sequences and apply this to secretin-stimulated studies with the aim of quantifying pancreatic exocrine function. A commercially available single-shot MRCP sequence was used in conjunction with a body phased-array coil ...

    journal_title:European radiology

    pub_type: 杂志文章


    authors: Punwani S,Gillams AR,Lees WR

    更新日期:2003-02-01 00:00:00

  • Coronary calcium score and computed tomography coronary angiography in high-risk asymptomatic subjects: assessment of diagnostic accuracy and prevalence of non-obstructive coronary artery disease.

    abstract:OBJECTIVES:The aim of the study was to compare the coronary artery calcium score (CACS) and computed tomography coronary angiography (CTCA) for the assessment of non-obstructive/obstructive coronary artery disease (CAD) in high-risk asymptomatic subjects. METHODS:Two hundred and thirteen consecutive asymptomatic subje...

    journal_title:European radiology

    pub_type: 杂志文章


    authors: Cademartiri F,Maffei E,Palumbo A,Seitun S,Martini C,Tedeschi C,La Grutta L,Midiri M,Weustink AC,Mollet NR,Krestin GP

    更新日期:2010-04-01 00:00:00

  • Wall enhancement on black-blood MRI is independently associated with symptomatic status of unruptured intracranial saccular aneurysm.

    abstract:OBJECTIVE:This study aims to investigate whether aneurysm wall enhancement (AWE) is independently associated with symptomatic status of unruptured intracranial aneurysms (UIAs). METHODS:One hundred thirty-nine consecutive patients (67 male, mean age 58 ± 11 years) with 79 symptomatic and 87 asymptomatic UIAs were imag...

    journal_title:European radiology

    pub_type: 杂志文章


    authors: Zhu C,Wang X,Eisenmenger L,Shi Z,Degnan A,Tian B,Liu Q,Hess C,Saloner D,Lu J

    更新日期:2020-12-01 00:00:00

  • Computed diffusion-weighted imaging using 3-T magnetic resonance imaging for prostate cancer diagnosis.

    abstract:OBJECTIVE:To assess the efficacy of computed diffusion-weighted images (cDWIs) of b = 2000 s/mm(2) (cDWI2000) generated from DWIs of b = 0 and 1000 for prostate cancer (PCa) diagnosis in comparison with that of measured original DWIs of b = 1000 (mDWI1000) and b = 2000(mDWI2000) using 3-T MRI. METHODS:Eighty patients ...

    journal_title:European radiology

    pub_type: 杂志文章


    authors: Ueno Y,Takahashi S,Kitajima K,Kimura T,Aoki I,Kawakami F,Miyake H,Ohno Y,Sugimura K

    更新日期:2013-12-01 00:00:00

  • Tracheobronchial stent insertions in the management of major airway obstruction in a patient with Hunter syndrome (type-II mucopolysaccharidosis).

    abstract::We report a case of a 22-year-old male with Hunter syndrome who developed progressive major airway obstruction and was treated with insertion of plastic and metallic stents, with dramatic improvement in the patient's symptomatic and functional status. To the best of our knowledge, this is the first reported case of en...

    journal_title:European radiology

    pub_type: 杂志文章


    authors: Davitt SM,Hatrick A,Sabharwal T,Pearce A,Gleeson M,Adam A

    更新日期:2002-02-01 00:00:00

  • The accuracy of teleradiologists in diagnosing COVID-19 based on a French multicentric emergency cohort.

    abstract:OBJECTIVES:To evaluate the accuracy of diagnoses of COVID-19 based on chest CT as well as inter-observer agreement between teleradiologists during on-call duty and senior radiologists in suspected COVID-19 patients. MATERIALS AND METHODS:From March 13, 2020, to April 14, 2020, consecutive suspected COVID-19 adult pati...

    journal_title:European radiology

    pub_type: 杂志文章


    authors: Nivet H,Crombé A,Schuster P,Ayoub T,Pourriol L,Favard N,Chazot A,Alonzo-Lacroix F,Youssof E,Ben Cheikh A,Balique J,Porta B,Petitpierre F,Bouquet G,Mastier C,Bratan F,Bergerot JF,Thomson V,Banaste N,Gorincour G

    更新日期:2020-10-29 00:00:00

  • White matter integrity associated with clinical symptoms in tinnitus patients: A tract-based spatial statistics study.

    abstract:OBJECTIVE:To assess the relationship between white matter (WM) integrity and clinical variables in tinnitus patients using diffusion tensor imaging (DTI). METHODS:Sixty-seven tinnitus patients and 39 healthy controls were enrolled in this study. The tinnitus duration, laterality, pitch and characteristics, and two psy...

    journal_title:European radiology

    pub_type: 杂志文章


    authors: Ryu CW,Park MS,Byun JY,Jahng GH,Park S

    更新日期:2016-07-01 00:00:00

  • Can magnetic resonance imaging predict the success of parturition in oxytocin-induced pregnant women?

    abstract::The aim of this study was to assess whether magnetic resonance imaging could predict the outcome of attempted vaginal delivery in a group of pregnant women whose parturition had to be induced by oxytocin. The signal intensity and morphology alterations in the cervix of 21 full-term pregnant women were analyzed before ...

    journal_title:European radiology

    pub_type: 杂志文章


    authors: Sabir N,Dicle O,Yurdakul B,Akkemik B

    更新日期:2000-01-01 00:00:00

  • Correction to: Cone-beam breast CT features associated with HER2/neu overexpression in patients with primary breast cancer.

    abstract::The original version of this article, published on 03 January 2020, unfortunately contained two mistakes. ...

    journal_title:European radiology

    pub_type: 杂志文章,已发布勘误


    authors: Zhu Y,Zhang Y,Ma Y,Li H,Liu A,Han P,Yin L,Lv N,Li Z,Lu H,Liu P,Ye Z

    更新日期:2020-06-01 00:00:00

  • Chemical exchange saturation transfer MR imaging of Parkinson's disease at 3 Tesla.

    abstract:OBJECTIVES:To demonstrate the feasibility of using chemical exchange saturation transfer (CEST) imaging to detect Parkinson's disease (PD) in patients at 3 Tesla. METHODS:Twenty-seven PD patients (17 men and 10 women; age range, 54-77 years) and 22 age-matched normal controls (13 men and 9 women; age range, 55-73 year...

    journal_title:European radiology

    pub_type: 杂志文章


    authors: Li C,Peng S,Wang R,Chen H,Su W,Zhao X,Zhou J,Chen M

    更新日期:2014-10-01 00:00:00

  • Radiation dose and fluoroscopy time of modern endovascular treatment techniques in patients with saccular unruptured intracranial aneurysms.

    abstract:OBJECTIVES:Modern endovascular treatment of unruptured intracranial aneurysms (UIAs) demands for observance of diagnostic reference levels (DRLs). The national DRL (250 Gy cm2) is only defined for coiling. We provide dosimetric data for the following procedures: coiling, flow diverter (FD), Woven EndoBridge (WEB), comb...

    journal_title:European radiology

    pub_type: 杂志文章


    authors: Forbrig R,Ozpeynirci Y,Grasser M,Dorn F,Liebig T,Trumm CG

    更新日期:2020-08-01 00:00:00

  • Comparison of image quality and radiation dose between split-filter dual-energy images and single-energy images in single-source abdominal CT.

    abstract:OBJECTIVES:To compare image quality and radiation dose of abdominal split-filter dual-energy CT (SF-DECT) combined with monoenergetic imaging to single-energy CT (SECT) with automatic tube voltage selection (ATVS). METHODS:Two-hundred single-source abdominal CT scans were performed as SECT with ATVS (n = 100) and SF-D...

    journal_title:European radiology

    pub_type: 杂志文章


    authors: Euler A,Obmann MM,Szucs-Farkas Z,Mileto A,Zaehringer C,Falkowski AL,Winkel DJ,Marin D,Stieltjes B,Krauss B,Schindera ST

    更新日期:2018-08-01 00:00:00

  • The diagnostic performance of reduced-dose CT for suspected appendicitis in paediatric and adult patients: A systematic review and diagnostic meta-analysis.

    abstract:OBJECTIVE:To evaluate the diagnostic performance of reduced-dose CT for suspected appendicitis. METHODS:A systematic search of the MEDLINE and EMBASE databases was carried out through to 10 January 2017. Studies evaluating the diagnostic performance of reduced-dose CT for suspected appendicitis in paediatric and adult...

    journal_title:European radiology

    pub_type: 杂志文章,meta分析,评审


    authors: Yoon HM,Suh CH,Cho YA,Kim JR,Lee JS,Jung AY,Kim JH,Lee JY,Kim SY

    更新日期:2018-06-01 00:00:00

  • The role of imaging in 2019 novel coronavirus pneumonia (COVID-19).

    abstract::Almost the entire world, not only China, is currently experiencing the outbreak of a novel coronavirus that causes respiratory disease, severe pneumonia, and even death. The outbreak began in Wuhan, China, in December of 2019 and is currently still ongoing. This novel coronavirus is highly contagious and has resulted ...

    journal_title:European radiology

    pub_type: 杂志文章,评审


    authors: Yang W,Sirajuddin A,Zhang X,Liu G,Teng Z,Zhao S,Lu M

    更新日期:2020-09-01 00:00:00

  • Clinical management of focal liver lesions: the key role of real-time contrast-enhanced US.

    abstract::Ultrasonography (US) is the most commonly used liver imaging modality worldwide. Unfortunately, it has limited sensitivity in the detection of small tumor nodules. Moreover, US findings are often nonspecific, as appearances of benign and malignant liver lesions overlap. The introduction of microbubble contrast agents ...

    journal_title:European radiology

    pub_type: 杂志文章,评审


    authors: Lencioni R,Della Pina C,Crocetti L,Bozzi E,Cioni D

    更新日期:2007-12-01 00:00:00

  • Current diagnostic approaches to subarachnoid haemorrhage.

    abstract::Over the past decade, significant advances have been made in the field of subarachnoid haemorrhage (SAH). Prompt diagnosis with high-resolution CT and intensive critical care support remain key aspects of good patient management. Early identification and definitive treatment of underlying ruptured aneurysms is general...

    journal_title:European radiology

    pub_type: 杂志文章,评审


    authors: U-King-Im JM,Koo B,Trivedi RA,Higgins NJ,Tay KY,Cross JJ,Antoun NM,Gillard JH

    更新日期:2005-06-01 00:00:00

  • Consensus report from the 7th International Forum for Liver Magnetic Resonance Imaging.

    abstract:OBJECTIVES:Liver-specific MRI is a fast-growing field, with technological and protocol advancements providing more robust imaging and allowing a greater depth of information per examination. This article reports the evidence for, and expert thinking on, current challenges in liver-specific MRI, as discussed at the 7th ...

    journal_title:European radiology

    pub_type: 共识发展会议,杂志文章


    authors: Merkle EM,Zech CJ,Bartolozzi C,Bashir MR,Ba-Ssalamah A,Huppertz A,Lee JM,Ricke J,Sakamoto M,Sirlin CB,Ye SL,Zeng M

    更新日期:2016-03-01 00:00:00

  • Calcium scoring using virtual non-contrast images from a dual-layer spectral detector CT: comparison to true non-contrast data and evaluation of proportionality factor in a large patient collective.

    abstract:OBJECTIVE:Determination of coronary artery calcium scoring (CACS) in non-contrast computed tomography (CT) images has been shown to be an important prognostic factor in coronary artery disease (CAD). The objective of this study was to evaluate the accuracy of CACS from virtual non-contrast (VNC) imaging generated from ...

    journal_title:European radiology

    pub_type: 杂志文章


    authors: Gassert FG,Schacky CE,Müller-Leisse C,Gassert FT,Pahn G,Laugwitz KL,Makowski MR,Nadjiri J

    更新日期:2021-01-20 00:00:00