Free radicals. Formation, function and potential relevance in anaesthesia.

abstract：:Anaesthetists require a good knowledge of the excretion of drugs in breast milk and the potential hazards to suckling infants of drug ingestion via breast milk. A brief account of the physiology of lactation is given. The mechanisms of drug passage into breast milk are discussed followed by a review of the excretion i...

journal_title：Anaesthesia

authors： Lee JJ,Rubin AP

更新日期：1993-07-01 00:00:00

abstract：:Negatively marked multiple-choice questions (MCQs) are part of the assessment process in both the Primary and Final examinations for the fellowship of the Royal College of Anaesthetists. It is said that candidates who guess will lose marks in the MCQ paper. We studied candidates attending a pre-examination revision co...

journal_title：Anaesthesia

authors： Hammond EJ,McIndoe AK,Sansome AJ,Spargo PM

更新日期：1998-11-01 00:00:00

abstract：:We aimed to determine if using the EndoFlex tracheal tube on the first intubation attempt provided improved placement times and intubation success compared with a standard-type tracheal tube in 50 patients undergoing gynaecological surgery in a prospective, randomised, cross-over trial. We found that using the EndoFle...

journal_title：Anaesthesia

authors： Teoh WH,Sia AT,Fun WL

更新日期：2009-11-01 00:00:00

abstract：:Previous studies of patients have shown that anaesthesia with nitrous oxide (N2O) increases the plasma levels of total homocysteine. In a randomised, controlled trial we measured the plasma total homocysteine levels in patients undergoing general surgery before and after anaesthesia with and without N2O. Plasma total ...

journal_title：Anaesthesia

authors： Foschi D,Rizzi A,Zighetti ML,Bissi M,Corsi F,Trabucchi E,Mezzetti M,Cattaneo M

更新日期：2001-07-01 00:00:00

abstract：:We have studied the respiratory effects of 5 and 10 cmH2O pressure support ventilation during anaesthesia with 1.5% end-tidal concentration of isoflurane in nine healthy, spontaneously breathing, adult patients. Some of the patients demonstrated an irregular respiratory pattern with periods of apnoea and we therefore ...

journal_title：Anaesthesia

authors： Bhatt SB,Chui PT,Gin T,Tam YH,Oh TE

更新日期：1995-12-01 00:00:00

abstract：:Thirty-seven patients with a wide range of illnesses were studied during mechanical ventilation of the lungs in an intensive care unit. Fifteen were sedated with a continuous propofol infusion, with analgesia provided by bolus doses of papaveretum. Twelve received a continuous infusion of papaveretum, supplemented by ...

journal_title：Anaesthesia

authors： Harris CE,Grounds RM,Murray AM,Lumley J,Royston D,Morgan M

更新日期：1990-05-01 00:00:00

abstract：:A myriad of new intubation equipment has been introduced commercially since the appearance of Macintosh/Miller blades in the 1940s. We review the role of devices that are relevant to current clinical practice based on their presence in the scientific literature. The comparative performance of new vs traditional direct...

journal_title：Anaesthesia

authors： Behringer EC,Kristensen MS

更新日期：2011-12-01 00:00:00

abstract：:The use of a low-power nerve stimulator to aid nerve location during the performance of sciatic nerve block was compared with a conventional anatomically based technique. The success rate, both in terms of the production of an effective block and the duration of postoperative analgesia, was significantly higher in the...

journal_title：Anaesthesia

authors： Smith BE,Allison A

更新日期：1987-03-01 00:00:00

abstract：:We performed a retrospective audit of blood glucose control after introducing a new protocol for insulin infusion. The audit showed a sustained reduction in the median blood glucose, which decreased from 7.0 to 6.8 mmol x l(-1), primarily because of a reduction in the proportion of values above 6 mmol x l(-1). When we...

journal_title：Anaesthesia

authors： Bone EG,Young D,Chantler J

更新日期：2006-10-01 00:00:00

abstract：:Doxacurium was administered to 50 adult patients for determination of potency (n = 10), onset and duration of clinical relaxation (n = 40). Cumulative dose-response showed the ED95 to be 33.24 micrograms.kg-1 (95% confidence limits 27.4-39.3). Doxacurium 33 micrograms.kg-1 was then administered to four groups of 10 pa...

journal_title：Anaesthesia

authors： Maddineni VR,Cooper R,Stanley JC,Mirakhur RK,Clarke RS

更新日期：1992-07-01 00:00:00

abstract：:The effects of propofol during low flow (1.6 l.min-1.m-2) hypothermic (27-29 degrees C) cardiopulmonary bypass on systemic haemodynamic and metabolic variables were studied in 20 patients in a parallel group comparison. Patients in the control group underwent two consecutive control periods, whereas those in the propo...

journal_title：Anaesthesia

authors： Laycock GJ,Alston RP

更新日期：1992-05-01 00:00:00

abstract：:Post-spinal hypotension remains a common and clinically-important problem during caesarean section, and accurate pre-operative prediction of this complication might enhance clinical management. We conducted a prospective, single-centre, observational study of heart rate variability in 102 patients undergoing elective ...

journal_title：Anaesthesia

authors： Bishop DG,Cairns C,Grobbelaar M,Rodseth RN

更新日期：2017-05-01 00:00:00

abstract：:A case of central nervous system depression which developed 7 hours after an intrathecal injection of 4 mg of morphine is described. The patient lapsed into coma with bradypnoea and "pin-point' pupils and there was no response to naloxone 0.4 mg. Treatment was continued for 3 hours. No postoperative analgesics were re...

journal_title：Anaesthesia

authors： Sidi A,Davidson JT,Behar M,Olshwang D

更新日期：1981-11-01 00:00:00

abstract：:The stability of propofol emulsion following the addition of various amounts of lignocaine solution was investigated. The investigations used were macroscopic and microscopic observations and electroacoustic determination of both droplet size and zeta potential. Evidence of emulsion instability was present following t...

journal_title：Anaesthesia

authors： Lilley EM,Isert PR,Carasso ML,Kennedy RA

更新日期：1996-09-01 00:00:00

abstract：:We sought to determine whether the forced air convection warmers (nine Bair Huggers, Augustine Medical, and one Warm Touch, Mallinkrodt Medical) used in our operating theatres could be a source of microbial pathogens. Agar plates were placed directly in the air stream of the warmers. Four of these grew potentially pat...

journal_title：Anaesthesia

authors： Avidan MS,Jones N,Ing R,Khoosal M,Lundgren C,Morrell DF

更新日期：1997-11-01 00:00:00

abstract：:Apnoeic oxygenation refers to oxygenation in the absence of any patient or ventilator effort to move the lungs. This phenomenon was first described in humans in the mid-20th century but has seen renewed interest in the last decade following the demonstration of apnoeic oxygenation with low-flow, and subsequently high-...

journal_title：Anaesthesia

authors： Lyons C,Callaghan M

更新日期：2021-01-01 00:00:00

abstract：:Twelve patients had their arterial oxygen saturation measured pre-operatively and on days 1, 4 and 7 after laparotomy. Measurements were performed in the supine, sitting and standing positions on each day. Arterial oxygen saturation was significantly higher during sitting and standing on days 1 and 4 after operation c...

journal_title：Anaesthesia

authors： Mynster T,Jensen LM,Jensen FG,Kehlet H,Rosenberg J

更新日期：1996-03-01 00:00:00

abstract：:Twelve volunteers known to have airways that responded adversely to 2.0 MAC desflurane were recruited. Each volunteer inhaled three single breaths of each of 0.5, 1.0 and 2.0 MAC of sevoflurane, halothane, isoflurane, desflurane and balance air, with breaths of air between, whilst breathing nasally through a face mask...

journal_title：Anaesthesia

authors： Wilkes AR,Raj N,Hall JE

更新日期：2003-03-01 00:00:00

abstract：:In this prospective observational study we investigated the changes in cardiac index and mean arterial pressure in children when positioned prone for scoliosis correction surgery. Thirty children (ASA 1-2, aged 13-18 years) undergoing primary, idiopathic scoliosis repair were recruited. The cardiac index and mean arte...

journal_title：Anaesthesia

authors： Brown ZE,Görges M,Cooke E,Malherbe S,Dumont GA,Ansermino JM

更新日期：2013-07-01 00:00:00

abstract：:The effects of increasing concentrations of nitrous oxide 30, 50 and 70% on the hepatic circulation and hepatic oxygen consumption were investigated in seven normocapnic greyhounds. Hepatic arterial and portal venous blood flows were measured continuously using electromagnetic flow probes, and mean arterial pressure a...

journal_title：Anaesthesia

authors： Thomson IA,Hughes RL,Fitch W,Campbell D

更新日期：1982-05-01 00:00:00

abstract：:The use of a portable generator which liberates oxygen from hydrogen peroxide solutions has been investigated in veterinary anaesthesia to assess its potential as an alternative to conventional oxygen supplies both in emergency situations and in the event of failure of cylinder systems. The reliability of the supply a...

journal_title：Anaesthesia

authors： Hall LW,Kellagher RE,Fleet KJ

更新日期：1986-05-01 00:00:00

abstract：:The purpose of this double-blind study was to investigate the incidence of transient neurological symptoms after the use of isobaric lidocaine and isobaric prilocaine for spinal anaesthesia. Seventy patients (ASA 1-2, age between 18 and 70 years) were randomly assigned to two groups of 35 patients each, to receive eit...

journal_title：Anaesthesia

authors： de Weert K,Traksel M,Gielen M,Slappendel R,Weber E,Dirksen R

更新日期：2000-10-01 00:00:00

abstract：:Thirty-three patients who had undergone elective open cholecystectomy were studied in a prospective, randomised comparison of thoracic (n = 17) and lumbar (n = 16) epidural routes of administration of a mixture of bupivacaine 0.2% with fentanyl 10 micrograms.ml-1 for postoperative pain. Pain relief, cardiovascular sta...

journal_title：Anaesthesia

authors： Chisakuta AM,George KA,Hawthorne CT

更新日期：1995-01-01 00:00:00

abstract：:We assessed the effectiveness of early patient-controlled oral analgesia compared with parenteral analgesia in a randomised controlled non-inferiority trial of women undergoing elective caesarean section under regional anaesthesia. Seventy-seven women received multimodal paracetamol, ketoprofen and morphine analgesia....

journal_title：Anaesthesia

authors： Bonnal A,Dehon A,Nagot N,Macioce V,Nogue E,Morau E

更新日期：2016-05-01 00:00:00

abstract：:Conditions for tracheal intubation at 90 seconds, time to onset of maximum block and duration of clinical relaxation after five different doses of atracurium, which ranged from 0.4 to 1.0 mg/kg were studied in 200 adult patients who were anaesthetized with nitrous oxide, oxygen and halothane or fentanyl. The condition...

journal_title：Anaesthesia

authors： Mirakhur RK,Lavery GG,Clarke RS,Gibson FM,McAteer E

更新日期：1985-08-01 00:00:00

abstract：:Anaesthetic procedures for successful separation of pygopagus twins are described. A bony union in the sacral region and communication of the subarachnoid space in this region were the main abnormalities. Various anaesthetic problems during the operation and in the immediate postoperative period are discussed. ...

journal_title：Anaesthesia

authors： Roy M

更新日期：1984-12-01 00:00:00

abstract：:The management of childbirth, including epidural anaesthesia for Caesarean section is described in a patient with von Hippel-Lindau disease. The reasons for the choice of epidural anaesthesia are explained and the anaesthetic significance of the disease is discussed. ...

journal_title：Anaesthesia

authors： Matthews AJ,Halshaw J

更新日期：1986-08-01 00:00:00

abstract：:Measurements of intraocular pressure (IOP) by applanation tonometry in twelve patients undergoing lens extraction showed that a normocapnic anaesthetic technique using 0.4% trichloroethylene with controlled ventilation of the lungs (IPPV) with large tidal volumes (14 ml/kg) reduced IOP by 13--20%. There was only a sma...

journal_title：Anaesthesia

authors： Adams AP,Freedman A,Dart JK

更新日期：1979-06-01 00:00:00

abstract：:This study compared the analgesic efficacy of an epidural infusion of ropivacaine and ropivacaine with sufentanil following major knee surgery. In a double-blind clinical trial, 115 adult patients received either epidural ropivacaine (R group, 2 mg.ml(-1)), or ropivacaine (2 mg.ml(-1)) with sufentanil (RS group, 1 mic...

journal_title：Anaesthesia

authors： Lorenzini C,Moreira LB,Ferreira MB

更新日期：2002-05-01 00:00:00

abstract：:This is a review of 136 patients who have undergone corrective surgery for congenital heart disease with the aid of profound hypothermia in a 6-year period. Almost all patients were less than one year old and less than 10 kg. In 1979 the average age was 3.4 months and the average weight was 4.1 kg in 34 infants. The h...

journal_title：Anaesthesia

authors： Manners JM,Monro JL,Edwards JC

更新日期：1980-12-01 00:00:00