Abstract:
:We have studied the respiratory effects of 5 and 10 cmH2O pressure support ventilation during anaesthesia with 1.5% end-tidal concentration of isoflurane in nine healthy, spontaneously breathing, adult patients. Some of the patients demonstrated an irregular respiratory pattern with periods of apnoea and we therefore went on to study a further seven patients with a continuous 500 s recording of airflow. Pressure support ventilation augmented mean (SD) tidal volume from 212 (56) ml to 360 (88) ml at 5 cmH2O and to 509 (108) ml at 10 cmH2O (n = 16, p < 0.05). Mean (SD) respiratory rate decreased from 26 (6) min-1 to 22 (6) min-1 at 5 cmH2O and 17 (5) min-1 at 10 cmH2O pressure support (n = 16, p < 0.05). Mean (SD) inspiratory work of breathing decreased from 1.77 (0.70) J. min-1 to 0.31 (0.36) J.min-1 at 5 cmH2O and 0.16 (0.26) J.min-1 at 10 cmH2O pressure support ventilation (n = 9, p < 0.05). Analysis of the respiratory rhythm in the second group of seven patients revealed an oscillating respiratory pattern in four patients at 5 cmH2O and six of the seven patients at 10 cmH2O pressure support ventilation. The metabolic advantage of the decreased work of breathing during pressure support ventilation during anaesthesia is unlikely to balance the disadvantage of an oscillating respiratory rhythm.
journal_name
Anaesthesiajournal_title
Anaesthesiaauthors
Bhatt SB,Chui PT,Gin T,Tam YH,Oh TEdoi
10.1111/j.1365-2044.1995.tb05944.xsubject
Has Abstractpub_date
1995-12-01 00:00:00pages
1026-30issue
12eissn
0003-2409issn
1365-2044journal_volume
50pub_type
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