Abstract:
:Little is known about the haemodynamic effects of inhaled xenon on regional organ perfusion. The aim of this study was to investigate the effect of 79% xenon ventilation on organ perfusion in pigs. We investigated 10 pigs, which were randomly allocated to receive either xenon 79% or total intravenous anaesthesia (TIVA)/oxygen anaesthesia. Microspheres were used to determine organ perfusion. The following regions of interest were investigated: cerebral cortex, medulla oblongata, brainstem, cerebellum, liver, kidney, small intestine, colon, muscle, skin and heart. The results demonstrated a significant increase in regional perfusion in the brainstem (+63%), cerebral cortex (+38%), medulla oblongata (+35%) and cerebellum (+34%). All other organs showed no significant change in regional perfusion. We conclude that xenon should be used with caution in clinical situations associated with pathological increases in intracranial pressure, e.g. neurosurgical procedures, head injury, cerebral mass lesions or stroke.
journal_name
Anaesthesiajournal_title
Anaesthesiaauthors
Schmidt M,Marx T,Kotzerke J,Lüderwald S,Armbruster S,Topalidis P,Schirmer U,Reinelt Hdoi
10.1046/j.1365-2044.2001.02322.xsubject
Has Abstractpub_date
2001-12-01 00:00:00pages
1154-9issue
12eissn
0003-2409issn
1365-2044pii
2322journal_volume
56pub_type
杂志文章相关文献
ANAESTHESIA文献大全abstract::In this prospective study, cardiac output was measured in 38 intensive care unit patients before and after a fluid challenge, using both pulse contour analysis (Nexfin(®); BMEYE, Amsterdam, the Netherlands) and transthoracic echocardiography. The ability of the Nexfin device to detect significant changes in the veloci...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/anae.12341
更新日期:2013-09-01 00:00:00
abstract::Despite numerous guidelines on the management of anaemia in surgical patients, there is no pragmatic guidance for the diagnosis and management of anaemia and iron deficiency in the postoperative period. A number of experienced researchers and clinicians took part in a two-day expert workshop and developed the followin...
journal_title:Anaesthesia
pub_type: 共识发展会议,杂志文章,评审
doi:10.1111/anae.14358
更新日期:2018-11-01 00:00:00
abstract::The cardiovascular effects of 20 ml 0.75% bupivacaine with adrenaline 5 micrograms/ml injected epidurally were compared with those of 20 ml 0.75% ropivacaine with adrenaline. Cardiovascular measurements were performed with a transthoracic electrical bioimpedance monitor. The maximum mean arterial blood pressure decrea...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1991.tb09544.x
更新日期:1991-05-01 00:00:00
abstract::An internal jugular catheter, which was inserted into a patient with a traumatic haemopneumothorax, accidentally entered the pleural cavity. This was initially undetected because the two signs most frequently used to confirm correct placement, those of blood reflux and fluctuation of central venous pressure with respi...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1992.tb01949.x
更新日期:1992-01-01 00:00:00
abstract::Malignant obstructive jaundice is associated with poor aerobic capacity. We measured oxygen consumption and oxygen extraction (arterial-venous oxygen content) in the legs of nine patients during cardiopulmonary exercise testing before pancreaticoduodenectomy. The median (IQR [range]) peak oxygen consumption was 67 (49...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/anae.12478
更新日期:2014-01-01 00:00:00
abstract::Anaesthesia is a critical and complex process that extends from the pre-operative assessment through to the postoperative management of patients. Handover of responsibility for logistical as opposed to patient-orientated reasons may compromise that process of care. If such handover becomes inevitable with shift-based ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.2004.03760.x
更新日期:2004-07-01 00:00:00
abstract::A high frequency oscillator and its interface with the Siemens 900C ventilator form a combined high frequency oscillator and intermittent positive pressure ventilator. This combined high frequency ventilator is designed for use in selected cases of refractory hypoxaemia. ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1995.tb15114.x
更新日期:1995-07-01 00:00:00
abstract::Cardiac output can be measured accurately by transpulmonary arterial thermodilution using the PiCCO (Pulsion Medical Systems, Munich, Germany) system with a femoral artery catheter. We have investigated the accuracy of a new 50 cm 4 French gauge radial artery catheter and the ability to use the system with a shorter r...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.2004.03710.x
更新日期:2004-06-01 00:00:00
abstract::Many new supraglottic airway devices have been recently introduced, their development motivated by the need for a single-use equivalent to the original re-usable laryngeal mask airway. We performed a randomised cross-over study in spontaneously breathing patients comparing the re-usable Laryngeal Mask Airway-Classic (...
journal_title:Anaesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1365-2044.2005.04461.x
更新日期:2006-02-01 00:00:00
abstract::Nimodipine is widely used in patients with aneurysmal subarachnoid haemorrhage for the prevention and treatment of delayed ischaemic neurological deficits. Intravenous nimodipine has significant vasodilatory properties and may compromise the achievement of haemodynamic targets in patients who receive hypertensive hype...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章
doi:10.1111/j.1365-2044.1997.112-az0105.x
更新日期:1997-05-01 00:00:00
abstract::We tested whether prophylactic droperidol and ondansetron, in combination with a moderate dose of dexamethasone, were equally effective in reducing nausea and vomiting after tonsillectomy in children and that both were superior to saline with dexamethasone. We randomly allocated 300 children to intravenous saline, dro...
journal_title:Anaesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1111/anae.13907
更新日期:2017-07-01 00:00:00
abstract::The most appropriate technique for performing tracheal intubation in patients with cervical spine injury is debatable. Recently, a new device enabling blind oral intubation (Augustine Guide) with the patient's head and neck in the neutral position has been introduced. The aim of this study was to compare the extent of...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1994.tb03364.x
更新日期:1994-02-01 00:00:00
abstract::The Airtraq laryngoscope is a single-use laryngoscope designed to facilitate tracheal intubation in patients with either normal or difficult airways. The aim of this systematic review and meta-analysis was to compare the Airtraq with the conventional Macintosh laryngoscope. Data were retrieved from Medline, Embase, th...
journal_title:Anaesthesia
pub_type: 杂志文章,meta分析,评审
doi:10.1111/j.1365-2044.2011.06871.x
更新日期:2011-12-01 00:00:00
abstract::Increased duration of anaesthetic administration has implications for recovery from anaesthesia, has cardiovascular effects, and potential for toxicity through metabolism and breakdown of the anaesthetics. Recovery of function after desflurane or sevoflurane anaesthesia, because of the low blood gas and tissue solubil...
journal_title:Anaesthesia
pub_type: 杂志文章,评审
doi:10.1111/j.1365-2044.1995.tb06183.x
更新日期:1995-10-01 00:00:00
abstract::Plasma concentrations of lignocaine were determined in six ASA 1 children treated with thoracic paravertebral blockade. Peak concentrations ranged between 1.7 and 3.0 micrograms.ml-1 after a bolus injection of lignocaine 0.5 ml.kg-1 (lignocaine 10 mg.ml-1 with adrenaline 5 micrograms.ml-1) and peak plasma concentratio...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1993.tb07473.x
更新日期:1993-11-01 00:00:00
abstract::The elderly are a group of patients who would seem ideally suited to day surgery. However, age was initially regarded as a potential barrier to this process. We conducted a retrospective review of 1647 elderly patients (> 70 years of age) over a two-year period. Our results show a favourable outcome for these patients...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.2004.03560.x
更新日期:2004-01-01 00:00:00
abstract::Thirty-six healthy patients, ASA 1, aged 16-41 years, scheduled for elective plastic surgery were studied to determine if thoracocervical or lumbar epidural blocks affected the lag time of the pulse oximeter response. Patients were allocated to receive thoracocervical epidural block (n = 20) (group 1) (lignocaine 1%) ...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章
doi:10.1111/j.1365-2044.1996.tb15041.x
更新日期:1996-12-01 00:00:00
abstract::Epidural sufentanil 50 micrograms was compared with intramuscular buprenorphine 0.3 mg for postoperative pain relief. Patients were assigned randomly to one of two treatment groups and received both an intramuscular and epidural injection, one of which was a placebo. Onset of pain relief was faster and quality of anal...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1365-2044.1987.tb05222.x
更新日期:1987-11-01 00:00:00
abstract::We studied seven analytical methods of estimating the plasma volume from the decay curves of indocyanine green. Fifteen volunteers received 1.0 mg.kg-1 of the dye by intravenous injection and the plasma concentration was measured continuously using spectrophotometry. Plasma volumes were calculated using three single-r...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1997.249-az0389.x
更新日期:1997-12-01 00:00:00
abstract::The aims of noninvasive ventilation include the correction of hypoventilation and unloading of inspiratory muscles. Volume cycled flow generators, bi-level positive airway pressure and continuous positive airway pressure techniques have all been used with face and nasal masks. We have compared these modes of ventilato...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1365-2044.1994.tb14173.x
更新日期:1994-04-01 00:00:00
abstract::We have compared the performance of the single use laryngeal airway devices Softseal and LMA-Unique in a randomised comparative trial in anaesthetised healthy patients who did not receive neuromuscular blockade. Primary outcome was success of airway placement. Secondary outcomes included manipulations and complication...
journal_title:Anaesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1365-2044.2005.04330.x
更新日期:2005-12-01 00:00:00
abstract::This study compares retrospectively the postoperative analgesia provided via intravenous opioids with continuous regional techniques (interpleural and epidural infusions) administered as a clinical routine by an anaesthesia-based Acute Pain Service. In 2630 patients no severe complications resulting in morbidity or mo...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1994.tb03528.x
更新日期:1994-06-01 00:00:00
abstract::A randomised, controlled, crossover trial was designed to assess the safety and effectiveness of oral midazolam sedation for orthodontic extractions. Forty-six ASA physical status I children aged 10-16 years were recruited. Each child required two treatment sessions. Sedation with either oral midazolam 0.5 mg.kg-1 or ...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1046/j.1365-2044.2002.02784.x
更新日期:2002-09-01 00:00:00
abstract::Extradural analgesia is well established for relief of pain but in certain cases unusual difficulties may be encountered. We report our experiences of a patient with congenital ichthyosis who required extradural analgesia for the relief of pain in labour. ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1984.tb09507.x
更新日期:1984-02-01 00:00:00
abstract::The C-MAC comprises a Macintosh blade connected to a video unit. The familiarity of the Macintosh blade, and the ability to use the C-MAC as a direct or indirect laryngoscope, may be advantageous. We wished to compare the C-MAC with Macintosh, Glidescope and Airtraq laryngoscopes in easy and simulated difficult laryng...
journal_title:Anaesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1365-2044.2010.06307.x
更新日期:2010-05-01 00:00:00
abstract::Severe acute respiratory syndrome-corona virus-2, which causes coronavirus disease 2019 (COVID-19), is highly contagious. Airway management of patients with COVID-19 is high risk to staff and patients. We aimed to develop principles for airway management of patients with COVID-19 to encourage safe, accurate and swift ...
journal_title:Anaesthesia
pub_type: 杂志文章,实务指引
doi:10.1111/anae.15054
更新日期:2020-06-01 00:00:00
abstract::A new approach to the internal jugular vein is described which keeps the head and neck in the neutral position and uses bony and cartilaginous landmarks for guidelines. Venous puncture is made along an axial line drawn superiorly from the lateral edge of the bony depression caused by the insertion of the sternocleidom...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1994.tb03421.x
更新日期:1994-03-01 00:00:00
abstract::A method is described whereby gas powered, minute volume divider, ventilators may be adapted to provide intermittent mandatory ventilation. ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1976.tb11979.x
更新日期:1976-11-01 00:00:00
abstract::Supraglottic airway devices such as the ProSeal Laryngeal Mask Airway (PLMA) and Laryngeal Tube-Suction Airway (LTS) that provoke the least stress responses could be beneficial in many situations, especially in patients with cardiovascular disease. We compared the haemodynamic and catecholamine stress response of the ...
journal_title:Anaesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1365-2044.2006.04548.x
更新日期:2006-04-01 00:00:00
abstract::One hundred patients undergoing microsurgery of the ear were anaesthetised using thiopentone, nitrous oxide, oxygen and either halothane or enflurane with spontaneous respiration. Blood pressure was reduced to approximately 70 mmHg by the use of hypotensive agents. The efficacy of halothane and enflurane in producing ...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1365-2044.1982.tb01718.x
更新日期:1982-10-01 00:00:00