Spinal narcotics and central nervous system depression.

Abstract:

:A case of central nervous system depression which developed 7 hours after an intrathecal injection of 4 mg of morphine is described. The patient lapsed into coma with bradypnoea and "pin-point' pupils and there was no response to naloxone 0.4 mg. Treatment was continued for 3 hours. No postoperative analgesics were required for 126 hours. The problems associated with the use of intrathecal opiates are reviewed, delay in onset being the usual feature. Use of hyperbaric solutions of the narcotic and maintenance of a head-up posture may protect against respiratory depression.

journal_name

Anaesthesia

journal_title

Anaesthesia

authors

Sidi A,Davidson JT,Behar M,Olshwang D

doi

10.1111/j.1365-2044.1981.tb08679.x

subject

Has Abstract

pub_date

1981-11-01 00:00:00

pages

1044-7

issue

11

eissn

0003-2409

issn

1365-2044

journal_volume

36

pub_type

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