The effect of midazolam premedication on implicit memory activation during alfentanil-nitrous oxide anaesthesia.

Abstract:

:Eighty-three patients were given midazolam 0.1 mg.kg-1 by intramuscular injection as premedication before general anaesthesia with alfentanil-nitrous oxide. During anaesthesia patients were presented (through headphones) with either statements about common facts of some years ago (group A) (n = 43) or new verbal associations, e.g. names of fictitious, nonfamous people (group B) (n = 40). In a previous study with the same anaesthetic technique, but without premedication there was significant activation of implicit memory (p < 0.001). In this study we found no explicit or implicit memory for the auditory information presented during anaesthesia. Midazolam premedication can prevent implicit memory activation during alfentanil-nitrous oxide anaesthesia.

journal_name

Anaesthesia

journal_title

Anaesthesia

authors

De Roode A,Jelicic M,Bonke B,Bovill JG

doi

10.1111/j.1365-2044.1995.tb04553.x

subject

Has Abstract

pub_date

1995-03-01 00:00:00

pages

191-4

issue

3

eissn

0003-2409

issn

1365-2044

journal_volume

50

pub_type

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