Abstract:
:Haemodynamic instability is a recognised phenomenon in critically ill patients undergoing hyperbaric therapy. Instability may result from the effects of ambient pressure on the cardiovascular system, devices involved in infusion of drugs and fluids, or a combination of the two. The effect of hyperbaric pressure on air-containing spaces in syringes has not been previously measured. We connected 60-ml syringes (Terumo Corporation, Tokyo, Japan) containing coloured water to low volume extensions via three-way taps. We examined the effect of pressurisation to 2.4 and 2.8 atmospheres absolute (ATA) on the syringes by measuring the displacement of the coloured water in the low volume extension set. There was compression of air spaces within the syringe causing retrograde flow of fluid within the low volume extension set. The mean (95% CI) change in volume was 154 (141-168) microl at 2.4 ATA, and 197 (183-212) microl at 2.8 ATA (both p < 0.0001). We conclude that hyperbaric exposure may cause clinically significant changes in syringe function at infusion rates < 100 ml. h(-1).
journal_name
Anaesthesiajournal_title
Anaesthesiaauthors
Hopson AS,Greenstein Adoi
10.1111/j.1365-2044.2007.05027.xsubject
Has Abstractpub_date
2007-06-01 00:00:00pages
602-4issue
6eissn
0003-2409issn
1365-2044pii
ANA5027journal_volume
62pub_type
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