Abstract:
:The speed of onset of neuromuscular blockade was measured for increasing doses of vecuronium. Onset times were found to be shorter with larger doses, up to a limit of ED95 X 3 (0.15 mg/kg). Thereafter, increasing the dose, even up to ED95 X 8 (0.4 mg/kg), did not appreciably shorten the time to full neuromuscular blockade. The clinical implications of, and pharmacokinetic basis for, these findings are discussed.
journal_name
Anaesthesiajournal_title
Anaesthesiaauthors
Casson WR,Jones RMdoi
10.1111/j.1365-2044.1986.tb13217.xsubject
Has Abstractpub_date
1986-04-01 00:00:00pages
354-7issue
4eissn
0003-2409issn
1365-2044journal_volume
41pub_type
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