Abstract:
:Alkalinisation of local anaesthetic drugs is a controversial technique for improving regional blockade. Forty-two patients scheduled for upper limb surgery received axillary brachial plexus anaesthesia using a cannula technique. Patients were randomly allocated to receive either lignocaine 1.5% with 1 in 200,000 adrenaline (pH = 4.2) or lignocaine 1.5% with 1 in 200,000 adrenaline (pH = 7.2). There was no significant difference in the incidence of satisfactory blockade or distribution of anaesthesia between the two groups. The percentage of patients with complete anaesthesia at 10, 20 and 30 min following injection was significantly increased in the alkalinized group with regard to the ulnar and median nerves, and the median cutaneous nerve of the arm (p < 0.05). In the alkalinized group, there was a significant reduction in the time to useful anaesthesia and a reduced requirement for adjuvants (p < 0.05). There was no effect on the duration of anaesthesia.
journal_name
Anaesthesiajournal_title
Anaesthesiaauthors
Gormley WP,Hill DA,Murray JM,Fee JPdoi
10.1111/j.1365-2044.1996.tb07712.xsubject
Has Abstractpub_date
1996-02-01 00:00:00pages
185-8issue
2eissn
0003-2409issn
1365-2044journal_volume
51pub_type
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