Renal cortical necrosis at presentation in a patient with systemic lupus erythematosus: an autopsy case report.

Abstract:

:Systemic lupus erythematosus (SLE) is a multisystemic autoimmune disorder. Renal involvement has the worst prognosis. However, renal cortical necrosis is extremely unusual in SLE. In this case report, we describe the autopsy findings in a young female patient with SLE presenting with renal failure. At autopsy, there was Libmann-Sacks endocarditis with multiorgan infarcts and renal cortical necrosis. Secondary antiphospholipid antibodies contribute to the cardiac and renal manifestations in SLE. We discuss the incidence and pathogenesis of endocarditis with differential diagnosis for cortical necrosis in a patient of SLE.

journal_name

Clin Rheumatol

journal_title

Clinical rheumatology

authors

Uppin MS,Rajasekhar L,Swetha H,Srinivasan VR,Prayaga AK

doi

10.1007/s10067-010-1395-5

subject

Has Abstract

pub_date

2010-07-01 00:00:00

pages

815-8

issue

7

eissn

0770-3198

issn

1434-9949

journal_volume

29

pub_type

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