Abstract:
:Systemic lupus erythematosus (SLE) is a multisystemic autoimmune disorder. Renal involvement has the worst prognosis. However, renal cortical necrosis is extremely unusual in SLE. In this case report, we describe the autopsy findings in a young female patient with SLE presenting with renal failure. At autopsy, there was Libmann-Sacks endocarditis with multiorgan infarcts and renal cortical necrosis. Secondary antiphospholipid antibodies contribute to the cardiac and renal manifestations in SLE. We discuss the incidence and pathogenesis of endocarditis with differential diagnosis for cortical necrosis in a patient of SLE.
journal_name
Clin Rheumatoljournal_title
Clinical rheumatologyauthors
Uppin MS,Rajasekhar L,Swetha H,Srinivasan VR,Prayaga AKdoi
10.1007/s10067-010-1395-5subject
Has Abstractpub_date
2010-07-01 00:00:00pages
815-8issue
7eissn
0770-3198issn
1434-9949journal_volume
29pub_type
杂志文章abstract:OBJECTIVES:The aim of this study is to analyze the prevalence of myositis-specific autoantibodies (MSAs) and to elucidate their associations with clinical features in Chinese patients with polymyositis (PM) and dermatomyositis (DM). METHODS:Twelve subsets of MSAs including anti-Mi-2, anti-TIF1-γ, anti-MDA5, anti-NXP2,...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-019-04503-7
更新日期:2019-08-01 00:00:00
abstract::The aim of this study was to describe how persons with rheumatoid arthritis (RA) of working age experience and handle their fatigue in everyday life. Six focus group discussions were conducted focusing on experiences of fatigue in 25 persons with RA (19 women, 6 men), aged 20-60 years. The discussions were recorded, t...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-012-2133-y
更新日期:2013-05-01 00:00:00
abstract::This study aimed to investigate the effects of colchicine on growth parameters in familial Mediterranean fever (FMF) patients. Fifty-one (29 girls, 22 boys) FMF patients were enrolled in the study. All of the patients were in the prepubertal stage and had not received colchicine treatment before the study. Anthropomet...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-015-3077-9
更新日期:2016-06-01 00:00:00
abstract::Monocytes are an important component in the innate immune system. However, studies to date have failed to conclude whether their levels are altered in patients with systemic lupus erythematosus (SLE). We applied the cytodiff counting method and comprehensively measured the circulating levels of distinct white blood ce...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-017-3787-2
更新日期:2017-10-01 00:00:00
abstract::This study aims to evaluate the impact of arthritis on the physical function of people living in a Maya-Yucateco rural community and to assess the association of known modifiable risk factors with the prevalence of overall arthritis and its main types (osteoarthritis and rheumatoid arthritis). Using a cross-sectional,...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-015-3084-x
更新日期:2016-07-01 00:00:00
abstract::Objectives of this study were to examine work disability (WD) and its leading causes in incident SLE patients. Data were derived from the Finnish nationwide registries to identify all non-retired, 18 to 64-year-old incident SLE patients between 2000 and 2007. Sick benefits and WD pensions and the causes for them were ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-018-4066-6
更新日期:2018-05-01 00:00:00
abstract::We reviewed the records of 315 patients with rheumatoid arthritis (RA) treated with low-dose methotrexate (MTX) and evaluated the conditions contributing to thrombocytopenia. Thirteen out of 315 patients with RA presented with low platelet counts (< or = 100.000/mm3). The age of these patients (51 +/- 12.6 years) did ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02230334
更新日期:1996-03-01 00:00:00
abstract::A number of laboratory variables, including Hb., ESR and several phase proteins, fluctuated in concord with the clinical signs of synovitis activity in patients with rheumatoid arthritis during a controlled study of 3 disease-modifying anti-rheumatic drugs (DMARD). The correlation between laboratory variables and clin...
journal_title:Clinical rheumatology
pub_type: 临床试验,杂志文章
doi:10.1007/BF02201028
更新日期:1987-06-01 00:00:00
abstract::Wegener's granulomatosis (WG) is a systemic granulomatous vasculitis that typically affects the upper airways, lungs and kidneys. Lymphadenopathy is rare in patients with WG. Here, we present the first case of WG whose initial manifestation was superficial lymphadenopathy (i.e. supraclavicular and axillary lymphadenop...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s100670200128
更新日期:2002-11-01 00:00:00
abstract:INTRODUCTION:The prevalence of herpes zoster (HZ) is high in patients with rheumatologic diseases. The incidence in patients with rheumatoid arthritis (RA) is at least twice as high as in healthy people. Nevertheless, little is known about humoral immunity against varicella zoster virus (VZV), in particular in patients...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-019-04563-9
更新日期:2019-09-01 00:00:00
abstract::Hyperimmunoglobulinemia D syndrome (HIDS) is newly recognized and resembles familial Mediterranean fever (FMF). It is inherited as an autosomal recessive trait. Mutation of the gene coding for mevalonate kinase is responsible for the disease. The gene is located at chromosome 12q24. The patients initially described we...
journal_title:Clinical rheumatology
pub_type: 信件
doi:10.1007/s10067-004-0953-0
更新日期:2005-02-01 00:00:00
abstract::We report a case of a 56-year-old woman with an alleged diagnosis of an acute coronary syndrome that was later correctly identified in our Cardiology Unit as antisynthetase syndrome (AS) with inflammatory cardiac involvement. In this case report, we focus on clinical features of this rare autoimmune disease aiming to ...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-019-04527-z
更新日期:2019-08-01 00:00:00
abstract::The objective of this study is to identify baseline factors associated with rheumatoid arthritis (RA) diagnosis at the end of 1-year follow-up in a cohort of patients with very recent onset arthritis. Incident cases with self-reported arthritis ( journal_title:Clinical rheumatology pub_type: 杂志文章 doi:10.1007/s10067-009-1206-z 更新日期:2009-10-01 00:00:00
abstract:OBJECTIVES:To test the psychometric properties of the United Kingdom's Commissioning for Quality in Rheumatoid Arthritis Patient-Reported Experience Measure (CQRA-PREM) in patients with spondyloarthritis (SpA) and rheumatoid arthritis (RA) and to implement this questionnaire in daily practice in the Netherlands. METHO...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-020-05076-6
更新日期:2020-10-01 00:00:00
abstract::The aims of this study were to find the characteristics and prevalence of nailfold capillary changes in a large series of patients with Behçet's disease (BD) and to analyze their possible relation to other clinical characteristics of the disease. We performed nailfold capillaroscopy in 128 randomly selected patients f...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-009-1106-2
更新日期:2009-05-01 00:00:00
abstract::The aim of this study was to determine whether the prolactin -1149 G/T polymorphism confers susceptibility to systemic lupus erythematous (SLE) and rheumatoid arthritis (RA). A meta-analysis was conducted for examining the associations between prolactin -1149 G/T polymorphism and susceptibility to SLE or RA using alle...
journal_title:Clinical rheumatology
pub_type: 杂志文章,meta分析
doi:10.1007/s10067-015-2904-3
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVE:Peer support is important for psychosocial well-being in patients with rheumatoid arthritis (RA). Our objective was to assess the interactions, engagement, and perceptions of participants in an online support group for patients with RA. METHODS:Participants were 18 years or older, diagnosed with RA within 10...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-020-04967-y
更新日期:2020-06-01 00:00:00
abstract::Angiotensin II, the major effective molecule of the renin-angiotensin system, plays a vital role in the development of systemic lupus erythematosus (SLE). To study angiotensin II type 1 receptor (AT1R) gene polymorphism at (A1166C) in Egyptian children with SLE and its correlation with serum ACE level and SLE manifest...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-018-4255-3
更新日期:2018-12-01 00:00:00
abstract::An understanding of the cytokine cascade in a rheumatoid joint has led to the development of new therapeutic options, including drugs targeting tumor necrosis factor-alpha (TNF-alpha). The safety profile of these agents in patients with hepatitis-induced liver disease, however, remains a concern because of risks assoc...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-009-1149-4
更新日期:2009-07-01 00:00:00
abstract::Clinical guidelines regarding anti-viral prophylaxis for HBV surface antigen (HBsAg) carriers starting anti-TNFα agents are not yet fully established, even in endemic regions of HBV infection. We retrospectively collected the clinical data of 52 HBsAg carriers with rheumatoid arthritis (RA) or ankylosing spondylitis (...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-012-1960-1
更新日期:2012-06-01 00:00:00
abstract::A 22-year-old African male with known sickle cell anaemia was referred by a Congolese medical centre with a request to improve his poor physical condition. He was unable to walk, stand or sit because his large joints and his spine were either ankylosed or very rigid. Radiographs showed joint fusion from the third to t...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s100670070047
更新日期:2000-01-01 00:00:00
abstract::Multilevel studies have gained importance for highlighting social inequalities in health. These associations have been reported previously in diseases such as arthritis and chronic pain. We conducted a cross-sectional study using multilevel analysis to identify individual and contextual factors associated with the var...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-014-2776-y
更新日期:2016-01-01 00:00:00
abstract::The objective of this study was to characterise the peripheral arthritis of spondyloarthritis (pSpA) excluding psoriatic-, inflammatory enteropathy-related, post-infectious reactive-SpA and arthritis associated with axial SpA/ankylosing spondylitis (axSpA/AS). Patients presenting with the clinical features of the broa...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-017-3720-8
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVES:(1) Development and validation of a composite ultrasound score (cUSS) for the diagnosis of carpal tunnel syndrome (CTS). (2) To predict treatment response after local corticosteroid injection. METHODS:Wrists of CTS patients and controls were evaluated with high-resolution ultrasound and cross-sectional area...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-020-05228-8
更新日期:2020-07-21 00:00:00
abstract::The objective of this study was to determine possible differences in the outcome of patients with rheumatoid arthritis (RA) with disease onset early and late in life. As part of a broader outcome study of RA which included patients seen in the division of Rheumatology of Hospital Universitario Marqués de Valdecilla of...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-004-1067-4
更新日期:2005-09-01 00:00:00
abstract:OBJECTIVE:To assess whether systemic sclerosis (SSc) is associated with total knee arthroplasty (TKA) outcomes. METHODS:We used the 1998-2014 US National Inpatient Sample. We conducted multivariable-adjusted logistic regression analyses to examine the association of a diagnosis of SSc with post-TKA in-hospital complic...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-019-04754-4
更新日期:2020-01-01 00:00:00
abstract::Juvenile idiopathic arthritis (JIA) is the most common chronic arthritis of childhood. Currently, it is characterized by seven categories. The enthesitis-related arthritis (ERA) category usually affects boys older than 6 years and presents with lower limb asymmetrical arthritis associated with enthesitis. Later, these...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-015-3029-4
更新日期:2015-11-01 00:00:00
abstract::In a great majority of patients with systemic lupus erythematosus (SLE) lymphocytotoxic antibodies (LCA) are detected. The reported prevalence depends on the methods of detection and definition of test-positivity. The pathogenetic role of LCA remains unclear. Different reports show that LCA can have an influence on mo...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/BF02229861
更新日期:1994-03-01 00:00:00
abstract::There are few reports about the coexistence of Sjögren's syndrome (SS) and ankylosing spondylitis (AS). To evaluate the frequency of SS in patients with AS. We studied 70 patients with AS presenting to the university outpatient clinic between January 2002 and November 2003. All the patients were asked about sicca symp...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-006-0255-9
更新日期:2007-02-01 00:00:00
abstract::Fibromyalgia syndrome (FMS) is characterized by chronic widespread pain and systemic symptoms. The aetiology and pathogenesis of fibromyalgia are not yet fully understood. Blood neutrophil/lymphocyte ratio (NLR) is a marker of systemic inflammatory response. Platelet distribution width (PDW) and mean platelet volume (...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-017-3647-0
更新日期:2017-08-01 00:00:00