In vitro susceptibility of Cryptococcus neoformans isolates from patients with acquired immunodeficiency syndrome.

Abstract:

:Cryptococcus neoformans strains from 26 individual patients with acquired immunodeficiency syndrome (AIDS) and three isolates from patients without AIDS were tested for their susceptibility to amphotericin B, flucytosine, ketoconazole, and miconazole nitrate. Ninety percent of the C neoformans isolates from patients with AIDS were inhibited by drug concentrations within achievable serum levels. The minimum fungicidal concentration of the four tested antifungal agents, however, exceeded obtainable cerebrospinal fluid levels.

journal_name

Arch Pathol Lab Med

authors

Poon M,Cronin DC 2nd,Wormser GP,Bottone EJ

subject

Has Abstract

pub_date

1988-02-01 00:00:00

pages

161-2

issue

2

eissn

0003-9985

issn

1543-2165

journal_volume

112

pub_type

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