Development and initial validation of a project-based rubric to assess the systems-based practice competency of residents in the clinical chemistry rotation of a pathology residency.

abstract：CONTEXT:Within the continent of Africa few countries have been able to practice pathology at the levels present in Europe and the Americas, and pediatric pathology does not exist as a stand-alone specialty. The author was invited by a colleague from Harvard Medical School, Boston, Massachusetts, to join a group of Nort...

journal_title：Archives of pathology & laboratory medicine

authors： Kaschula RO

更新日期：2013-06-01 00:00:00

abstract：:Findings of a histochemical and ultrastructural study of the mucogenic cells of congenital adenomatoid malformation of lung indicate that these cells share features with goblet cells of bronchial or intestinal origin and do not indicate a similarity to normal gastric epithelium or glands, as has been previously sugges...

journal_title：Archives of pathology & laboratory medicine

authors： Daroca PJ Jr

更新日期：1979-05-01 00:00:00

abstract：CONTEXT:Two recent studies have identified a high rate of microsatellite instability (MSI) in pancreatic neuroendocrine tumors (pNETs). Microsatellite instability is rare in small intestinal neuroendocrine tumors (NETs). It is unclear why there is discordance in the frequency of MSI in the 2 studies of pNETs and why th...

journal_title：Archives of pathology & laboratory medicine

authors： Arnason T,Sapp HL,Rayson D,Barnes PJ,Drewniak M,Nassar BA,Huang WY

更新日期：2011-12-01 00:00:00

abstract：CONTEXT:- Different types of mature B-cell lymphomas, including plasma cell neoplasms, exhibit distinct immunohistochemical profiles, which enable them to be correctly diagnosed. However, except for rare examples of lymphoma-specific immunohistochemistry, such as cyclin D1 in mantle cell lymphoma and annexin A1 in hair...

journal_title：Archives of pathology & laboratory medicine

authors： Wang HY,Zu Y

更新日期：2017-09-01 00:00:00

abstract：CONTEXT:Recently we have observed distinctive acidophilic intranuclear inclusions in cases of usual intraductal hyperplasia of the breast. Similar inclusions were described almost 20 years ago in cases of mammary hyperplasia. These correlated ultrastructurally with so-called helioid inclusions. However, there since has...

journal_title：Archives of pathology & laboratory medicine

authors： Lauer S,Oprea-Ilies G,Cohen C,Adsay V,Adams AL

更新日期：2011-06-01 00:00:00

abstract：:At autopsy in the past three years, a new complex of CNS lesions has appeared in 54% (50/93) of the brains of premature infant cadavers that have come from our neonatal intensive care unit. This complex consists of necrotizing lesions in the periventricular white matter and in the gray nuclei of the cerebral hemispher...

journal_title：Archives of pathology & laboratory medicine

authors： Grunnet ML

更新日期：1979-01-01 00:00:00

abstract：:We studied the use of stat (ie, statim--as soon as possible) laboratory tests at a university teaching hospital. For the 20 most frequently performed tests, 35.7% of the determinations were performed on a stat basis. The frequency with which a test was ordered on a stat basis ranged from 6.0% (for ESR) to 61.5% (amyla...

journal_title：Archives of pathology & laboratory medicine

authors： Chu RC,Williams SV,Eisenberg JM

更新日期：1982-12-01 00:00:00

abstract：CONTEXT:KRAS mutations can be detected in approximately 30% to 40% of all patients with colorectal cancer. Several recent studies have shown that patients with KRAS mutations in codons 12 or 13 in metastatic tumors do not benefit from anti-epidermal growth factor receptor therapy with cetuximab or panitumumab. OBJECTI...

journal_title：Archives of pathology & laboratory medicine

authors： Monzon FA,Ogino S,Hammond ME,Halling KC,Bloom KJ,Nikiforova MN

更新日期：2009-10-01 00:00:00

abstract：:Two hundred twenty-seven arteries from 17 autopsy patients having a history of Kawasaki disease were studied histopathologically and immunohistologically. Forty-five arteries in four cases (duration of illness ranging from 23 to 33 days) showed an arterial lesion characterized by reactive proliferative change of the m...

journal_title：Archives of pathology & laboratory medicine

authors： Masuda H,Shozawa T,Naoe S,Tanaka N

更新日期：1986-12-01 00:00:00

abstract：:The usual gross appearance of a renal oncocytoma is that of a well-circumscribed homogeneous tan-brown tumor with no evidence of necrosis or hemorrhage, but with a central fibrous scar. We describe a case of renal oncocytoma with the unusual gross appearance of a cystic tumor. While cystic change has occasionally been...

journal_title：Archives of pathology & laboratory medicine

authors： Ogden BW,Beckman EN,Rodriguez FH Jr

更新日期：1987-05-01 00:00:00

abstract：:Petrification of the auricle results in a rigid and immalleable ear. The etiology of such a finding is usually ectopic calcification. The condition has been associated with injurious processes, such as cold injury, and with various endocrinopathies, including Addison disease. In a significant number of cases, ossifica...

journal_title：Archives of pathology & laboratory medicine

authors： High WA,Larson MJ,Hoang MP

更新日期：2004-12-01 00:00:00

abstract：:Questionnaires sent to representative medicolegal jurisdictions in the United States showed that medicolegal necropsies comprise a substantial proportion of the total number of autopsies performed. Qualitative differences between customary hospital autopsies and their forensic counterparts include autopsy bias, the im...

journal_title：Archives of pathology & laboratory medicine

authors： Hirsch CS

更新日期：1984-06-01 00:00:00

abstract：CONTEXT:The Mre11-Rad50-NBS1 complex plays an important role in telomere maintenance. Recently, it has been proposed that alterations in Mre11 function may be contributing factors in the development of some tumors. Moreover, mutations of Mre11 have been demonstrated to cause reduced Mre11 immunostaining. OBJECTIVE:To ...

journal_title：Archives of pathology & laboratory medicine

authors： Nakanishi K,Kumaki F,Hiroi S,Mukai M,Ikeda E,Kawai T

更新日期：2006-09-01 00:00:00

abstract：:We have developed an inexpensive, microcomputer-based, multiuser hard disk system for surgical pathology that uses a commercially available word processor and data base manager, linked together by several BASIC programs written by us. System functions include keyboard input of patient demographic data and specimen inf...

journal_title：Archives of pathology & laboratory medicine

authors： Talamo TS,Losos FJ 3rd

更新日期：1985-01-01 00:00:00

abstract：CONTEXT.—:The separation of benign from malignant mesothelial proliferations is a difficult morphologic problem. Some mesotheliomas stain for programmed death ligand-1 (PD-L1). OBJECTIVE.—:To determine whether PD-L1 staining can separate mesotheliomas from reactive mesothelial proliferations (RMPs). DESIGN.—:We stain...

journal_title：Archives of pathology & laboratory medicine

authors： Derakhshan F,Ionescu D,Cheung S,Churg A

更新日期：2020-02-01 00:00:00

abstract：CONTEXT:- The Ki-67 index is strongly prognostic and is used as a surrogate marker to distinguish luminal A from luminal B breast cancer types. OBJECTIVE:- To investigate differences in Ki-67 index between core needle biopsy samples and matched surgical samples in breast cancer. DESIGN:- We included patients with inv...

journal_title：Archives of pathology & laboratory medicine

authors： Ahn S,Lee J,Cho MS,Park S,Sung SH

更新日期：2018-03-01 00:00:00

abstract：CONTEXT:The endomyocardial biopsy is the mainstay for monitoring acute allograft rejection in heart transplantation. Objective and accurate assessment of cellular and humoral types of rejection is important to optimize immunosuppressive therapy, avoid therapeutic complications, and improve patient outcome. The grading ...

journal_title：Archives of pathology & laboratory medicine

authors： Tan CD,Baldwin WM 3rd,Rodriguez ER

更新日期：2007-08-01 00:00:00

abstract：CONTEXT:Deletion of the short arm of chromosome 3 (3p deletion) is a cytogenetic abnormality generally associated with clear cell renal cell carcinoma, the most aggressive form of renal epithelial tumor. OBJECTIVE:To cytogenetically characterize 24 renal tumors in order to check the incidence and the type of 3p deleti...

journal_title：Archives of pathology & laboratory medicine

authors： Gayrard N,Cacheux V,Iborra F,Mourad G,Argilés A

更新日期：2008-06-01 00:00:00

abstract：:Glomus tumor is a benign mesenchymal neoplasm comprising less than 2% of soft tissue tumors. It is composed of cells resembling modified smooth muscle cells of the normal glomus body. The glomus body, a thermoregulator, is a specialized form of arteriovenous anastomosis localized in dermal and precoccygeal soft tissue...

journal_title：Archives of pathology & laboratory medicine

authors： Gombos Z,Zhang PJ

更新日期：2008-09-01 00:00:00

abstract：:In this time of significant change in pathology and medicine, pathology's future is uncertain. Many issues, including the emergence of molecular medicine, the demand for personalized medicine, confusing payment schemes, increasing governmental regulation, medical education challenges, administrative relationships, and...

journal_title：Archives of pathology & laboratory medicine

authors： Allen TC

更新日期：2012-02-01 00:00:00

abstract：:The significance of an elevated free thyroxine index (FTI) as an indicator of hyperthyroidism was studied while screening 651 elderly nursing home residents. Eleven subjects had FTI elevations. Most of these patients were chronically ill and/or malnourished. Clinical assessment, repeated FTI determinations, and subseq...

journal_title：Archives of pathology & laboratory medicine

authors： Drinka PJ,Nolten WE,Voeks S,Langer E,Carlson IH

更新日期：1991-12-01 00:00:00

abstract：CONTEXT:Although the early post-myelosuppressive chemotherapy pathologic changes of the marrow have been described, the rate and the histologic definition of recovery are not defined. OBJECTIVE:To study the rate of recovery of bone marrow in patients given myelosuppressive therapy for acute myelogenous leukemia, estab...

journal_title：Archives of pathology & laboratory medicine

authors： Khalil F,Cualing H,Cogburn J,Miles L

更新日期：2007-08-01 00:00:00

abstract：:Accurate diagnosis of salivary gland tumors can be challenging because of the many diagnostic entities, the sometimes extensive morphologic overlap, and the rarity of most tumor types. Ancillary testing is beginning to ameliorate some of these challenges through access to newer immunohistochemical stains and fluoresce...

journal_title：Archives of pathology & laboratory medicine

authors： Griffith CC,Schmitt AC,Little JL,Magliocca KR

更新日期：2017-03-01 00:00:00

abstract：:The pathogenesis of experimental meningococcal septicemia and the efficacy of heparin sodium therapy were evaluated by inoculating rabbits intraperitoneally with type B meningococci in mucin. Half the rabbits died, and the respiratory distress and circulatory failure that occurred during the terminal phase of the dise...

journal_title：Archives of pathology & laboratory medicine

authors： Gaskins RA Jr,Dalldorf FG

更新日期：1976-06-01 00:00:00

abstract：CONTEXT.—:Endometrial serous carcinoma is an aggressive subtype of endometrial cancer with the highest rate of recurrence and mortality among all histotypes. A recent clinical trial showed prolonged progression-free survival in advanced-stage and recurrent human epidermal growth factor receptor 2 (HER2)-positive endome...

journal_title：Archives of pathology & laboratory medicine

authors： Buza N

更新日期：2020-07-10 00:00:00

abstract：CONTEXT:Diagnosing epithelioid serosal lesions remains a challenge because numerous different processes-primary or secondary, benign or malignant-occur in body cavities, some of which are very rare. OBJECTIVES:To review the newest literature and to describe the morphologic criteria and immunohistochemical markers that...

journal_title：Archives of pathology & laboratory medicine

authors： Anttila S

更新日期：2012-03-01 00:00:00

abstract：:Accurate assessment of tissues for hematolymphoid neoplasms requires an integrated multiparameter approach. Although morphologic examination by light microscopy remains the mainstay of initial assessment for hematolymphoid neoplasms, immunophenotypic analysis by immunohistochemistry and/or flow cytometry is essential ...

journal_title：Archives of pathology & laboratory medicine

authors： Li S,Jaye DL,Bradley KT,Zhang L,Saxe D,Deeb G,Hill CE,Mann KP

更新日期：2017-03-01 00:00:00

abstract：CONTEXT:Hemolyzed specimens delay clinical laboratory results, proliferate unnecessary testing, complicate physician decisions, injure patients indirectly, and increase health care costs. OBJECTIVE:To determine quality improvement practices when hemolysis occurs. DESIGN:We used the College of American Pathologists (C...

journal_title：Archives of pathology & laboratory medicine

authors： Howanitz PJ,Lehman CM,Jones BA,Meier FA,Horowitz GL

更新日期：2015-07-01 00:00:00

abstract：CONTEXT:Pretransfusion testing of whole blood and red blood cell recipients is regulated by the federal government under the authority of the Clinical Laboratory Improvement Amendments of 1988. Regulated tests include determination of ABO group, Rh D type, antibody detection, antibody identification, and crossmatching....

journal_title：Archives of pathology & laboratory medicine

authors： Shulman IA,Maffei LM,Downes KA

更新日期：2005-08-01 00:00:00

abstract：:Investigations were carried out in order to determine whether animals with spontaneous diabetes are prone to develop skeletal lesions comparable to those found in diabetic human subjects. The present report deals with the ultrastructure of the cartilage of the hip joint of diabetic Chinese hamsters and nondiabetic con...

journal_title：Archives of pathology & laboratory medicine

authors： Silberberg R,Gerritsen G,Hasler M

更新日期：1976-01-01 00:00:00