State pathology societies and the future of pathology.

abstract：:The objective of this study was to evaluate conjunctival nevi for p53 gene mutations. We studied 11 conjunctival nevi by immunohistochemistry with the DO7 monoclonal p53 antibody as well as the cell proliferation marker, MIB1. Of the 11 cases, 2 were negative, 2 had less than 1%, and 7 had more than 2% p53 immunoposit...

journal_title：Archives of pathology & laboratory medicine

authors： Jay V,Ho M,Hunter W,Rootman D,Zielenska M

更新日期：1996-04-01 00:00:00

abstract：CONTEXT:Because the consequences of making an interpretive error on a proficiency test are more severe than those made on an educational challenge, the same slide may exhibit different performance characteristics in the 2 different settings. OBJECTIVE:The results of the 2006 College of American Pathologists Gynecologi...

journal_title：Archives of pathology & laboratory medicine

authors： Hughes JH,Bentz JS,Fatheree L,Souers RJ,Wilbur DC,Cytopathology Resource Committee, College of American Pathologists.

更新日期：2009-02-01 00:00:00

abstract：CONTEXT:The pancreas gives rise to an array of distinct neoplasms that can be solid, cystic, or intraductal and can recapitulate the various lines of differentiation present in the normal gland. OBJECTIVE:To develop an algorithmic approach to the diagnosis of pancreatic neoplasms that simplifies their pathologic evalu...

journal_title：Archives of pathology & laboratory medicine

authors： Klimstra DS,Pitman MB,Hruban RH

更新日期：2009-03-01 00:00:00

abstract：:The evolution of proteinuria in rabbits with experimentally induced chronic serum sickness was followed up longitudinally by analytical and quantitative assays. The results suggest that sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) is a more sensitive index of kidney malfunction than are total-p...

journal_title：Archives of pathology & laboratory medicine

authors： Patrick CC,Virella G,Fudenberg HH

更新日期：1980-06-01 00:00:00

abstract：CONTEXT:Primary intraosseous squamous cell carcinoma is a rare form of squamous cell carcinoma, arising within the jaws. OBJECTIVE:To clarify the clinicopathologic and behavioral spectrum of primary intraosseous squamous cell carcinoma. DESIGN:The clinical and pathologic findings, treatment, and follow-up data of 39 ...

journal_title：Archives of pathology & laboratory medicine

authors： Huang JW,Luo HY,Li Q,Li TJ

更新日期：2009-11-01 00:00:00

abstract：:We report the case of a primary breast rhabdomyosarcoma in a 51-year-old white woman. The tumor occupied the upper outer quadrant of the right breast. There was no association with the underlying pectoral muscle, and the patient was free of any other benign or malignant neoplastic processes outside the breast. Microsc...

journal_title：Archives of pathology & laboratory medicine

authors： Kyriazis AP,Kyriazis AA

更新日期：1998-08-01 00:00:00

abstract：:We evaluated the utility of a monoclonal antibody that recognizes Pneumocystis carinii as a diagnostic tool in specimens of bronchoalveolar lavage fluid and sputum from patients in whom a diagnosis of P carinii pneumonia was being considered. In addition to routine processing for diagnosis by morphologic recognition o...

journal_title：Archives of pathology & laboratory medicine

authors： Blumenfeld W,Kovacs JA

更新日期：1988-12-01 00:00:00

abstract：:A premature infant had three pseudoaneurysms of the thoracic and abdominal aorta secondary to umbilical artery catheterization and sepsis. The infant had septicemia as the direct result of bacterial contamination of an umbilical artery catheter with Staphylococcus aureus. The thoracic pseudoaneurysm caused massive hem...

journal_title：Archives of pathology & laboratory medicine

authors： Rabin E,Vye MV,Farrell EE

更新日期：1986-05-01 00:00:00

abstract：CONTEXT:Implementation of proficiency testing for gynecologic cytology was delayed 20 years because of challenges addressing the subjective nature of cytologic interpretation and replicating normal working conditions. Concern remains regarding test scoring, slide validation, test environment, and other issues. How thes...

journal_title：Archives of pathology & laboratory medicine

authors： Howell LP,Nayar R,Savaloja L,Tabbara S,Thomas N,Winkler B,Tworek J

更新日期：2013-02-01 00:00:00

abstract：CONTEXT:Aperio Technologies, Inc (Vista, California) provides a new immunohistochemistry (IHC) HER2 Image Analysis (IA) system that allows tuning of the intensity thresholds of the HER2/ neu scoring scheme to adapt to the staining characteristics of different reagents. OBJECTIVE:To compare the trainable IHC HER2 IA sy...

journal_title：Archives of pathology & laboratory medicine

authors： Nassar A,Cohen C,Agersborg SS,Zhou W,Lynch KA,Albitar M,Barker EA,Vanderbilt BL,Thompson J,Heyman ER,Lange H,Olson A,Siddiqui MT

更新日期：2011-07-01 00:00:00

abstract：CONTEXT:Tumors of the head and neck commonly arise from the squamous and respiratory mucosa that lines the nasal and oral cavity, sinuses, pharynx, and larynx. The rate of oropharyngeal cancers diagnosed among Americans younger than 50 years is increasing. Infection of the oropharynx and tonsils by the human papillomav...

journal_title：Archives of pathology & laboratory medicine

authors： Black CC,Bentley HA,Davis TH,Tsongalis GJ

更新日期：2010-12-01 00:00:00

abstract：:We performed x-ray microanalysis of autopsy specimens using a scanning-transmission electron microscopy mode. Tissues were obtained at necropsy from a patient with history of angiography using thorium dioxide and from a patient with hemochromatosis. X-ray microanalysis confirmed the presence of thorium and iron in the...

journal_title：Archives of pathology & laboratory medicine

authors： Landas S,Turner JW,Moore KC,Mitros FA

更新日期：1984-03-01 00:00:00

abstract：:Sarcoidlike granulomas may occur in association with Hodgkin lymphoma and non-Hodgkin lymphoma. The granulomas may be concomitant and so extensive that they obscure the malignant process. In addition, a sarcoidosis-lymphoma syndrome has been described in which there appears to be a relationship between sarcoidosis and...

journal_title：Archives of pathology & laboratory medicine

authors： Dunphy CH,Panella MJ,Grosso LE

更新日期：2000-01-01 00:00:00

abstract：CONTEXT:Diagnosing epithelioid serosal lesions remains a challenge because numerous different processes-primary or secondary, benign or malignant-occur in body cavities, some of which are very rare. OBJECTIVES:To review the newest literature and to describe the morphologic criteria and immunohistochemical markers that...

journal_title：Archives of pathology & laboratory medicine

authors： Anttila S

更新日期：2012-03-01 00:00:00

abstract：:Pulmonary adenocarcinoma is one of the most common types of lung cancer. Traditionally, adenocarcinomas have been divided based on their degree of resemblance to their parent tissues into 3 histopathologic types: well, moderately, and poorly differentiated. In the majority of cases, this schema is sufficient to catego...

journal_title：Archives of pathology & laboratory medicine

authors： Moran CA

更新日期：2006-07-01 00:00:00

abstract：:Renal solitary fibrous tumors (SFTs) have been reported infrequently. We report a 76-year-old man with a left renal mass that had previously been shown radiographically to be stable, but was now growing. Grossly, the mass measured 12 cm, was poorly circumscribed, and invaded beyond the renal capsule. Approximately 10%...

journal_title：Archives of pathology & laboratory medicine

authors： Fine SW,McCarthy DM,Chan TY,Epstein JI,Argani P

更新日期：2006-06-01 00:00:00

abstract：:The College of American Pathologists and the American Society of Human Genetics offer a proficiency testing program in clinical cytogenetics. Two hundred twenty-five laboratories now provide data for this survey, which was begun in 1986. Challenges have consisted of photographed metaphases, fixed lymphoblastoid cell s...

journal_title：Archives of pathology & laboratory medicine

authors： Hoeltge GA,Dewald G,Palmer CG,David-Nelson MA,Saikevych I,Patil S,Schwartz S,Schneider NR,Herrmann M

更新日期：1993-08-01 00:00:00

abstract：:Atherosclerosis can be defined as a disease process that occurs when the influx and deposition of cholesterol into the arterial wall exceed the egress of cholesterol from the arterial wall. This process is characterized by early deposition of cholesterol in and around arterial wall cells. The cholesterol is derived fr...

journal_title：Archives of pathology & laboratory medicine

authors： Mahley RW

更新日期：1983-08-01 00:00:00

abstract：:Evidence is presented that basophilic radial hairlines in the calcified layer of articular cartilage are in vivo microcracks. They were present in three of 25 normal patellas from subjects below the age of 50 years, in 20 of 25 recently fractured hips (average patient age, 77.3 years), and in 16 of 25 osteoarthritic t...

journal_title：Archives of pathology & laboratory medicine

authors： Sokoloff L

更新日期：1993-02-01 00:00:00

abstract：:Examination of the bone marrow poses several unique challenges to the pathologist: it is a semisolid organ without helpful gross correlation, it exists in a dynamic state with the peripheral blood and other organs of the lymphohemopoietic system, and the diagnosis of diseases affecting bone marrow often depends heavil...

journal_title：Archives of pathology & laboratory medicine

authors： Hasserjian RP

更新日期：2008-04-01 00:00:00

abstract：CONTEXT:Flow cytometric immunophenotyping is a useful ancillary tool in the diagnosis and subclassification of acute myeloid leukemias (AMLs). A recent study concluded that CD64 is sensitive and specific for distinguishing AMLs with a monocytic component (ie, AML M4 and AML M5) from other AML subtypes. However, in that...

journal_title：Archives of pathology & laboratory medicine

authors： Dunphy CH,Tang W

更新日期：2007-05-01 00:00:00

abstract：:Mucosa-associated lymphoid tissue (MALT) lymphomas are low-grade B-cell lymphomas that occur in a variety of extranodal sites but rarely as a primary hepatic lymphoma. We describe the histological findings, immunophenotype, and immunohistochemistry of one such lymphoma found incidentally in a 69-year-old woman. The ly...

journal_title：Archives of pathology & laboratory medicine

authors： Kirk CM,Lewin D,Lazarchick J

更新日期：1999-08-01 00:00:00

abstract：:The sophomore pathology course at the University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Piscataway, was substantially modified with the intention of promoting guided, independent learning. The emphasis has been shifted from lectures to other modalities of instruction. This article...

journal_title：Archives of pathology & laboratory medicine

authors： Raskova J,Martin EG,Trelstad RL,Shea SM

更新日期：1989-02-01 00:00:00

abstract：:Ciliated hepatic foregut cysts are rare congenital lesions derived from the embryologic foregut. They are considered benign, and a review of 64 published cases revealed no instances of malignant transformation. We report a case of squamous cell carcinoma arising in a ciliated hepatic foregut cyst in a 51-year-old man....

journal_title：Archives of pathology & laboratory medicine

authors： Vick DJ,Goodman ZD,Ishak KG

更新日期：1999-11-01 00:00:00

abstract：:We report a case of primary cerebral lymphoma metastasizing to the kidney with exclusive involvement of the glomeruli. We discuss the possible explanations of this unusual phenomenon, and present some of the unusual clinical features of the case. Nephropathologists interpreting glomerular hypercellularity should alway...

journal_title：Archives of pathology & laboratory medicine

authors： Iskandar SS,Jennette JC,Weis LS

更新日期：1985-06-01 00:00:00

abstract：:This project was designed to evaluate different criteria used in the interpretation of the human immunodeficiency virus type 1 (HIV-1) Western blot assay on a group of serum samples blinded to the examiner that were collected from individuals attending three different public health departments in central North Carolin...

journal_title：Archives of pathology & laboratory medicine

authors： O'Gorman MR,Weber D,Landis SE,Schoenbach VJ,Mittal M,Folds JD

更新日期：1991-01-01 00:00:00

abstract：:A case of epithelioid sarcoma was studied light microscopically, ultrastructurally, and immunohistologically. The tumor was a deep antebrachial mass in a 57-year-old man, and led to antebrachial amputation. Light microscopically, the tumor consisted of nodules that often had central necrosis. The cells were uniform, w...

journal_title：Archives of pathology & laboratory medicine

authors： Miettinen M,Lehto VP,Vartio T,Virtanen I

更新日期：1982-11-01 00:00:00

abstract：:The role of the Ito cells in perivenular and intralobular scarring in alcoholic liver disease was examined morphologically. There was a substantial decrease in the number of Ito cells in the midzone of the hepatic lobule in both fatty liver and alcoholic hepatitis as judged by light microscopy. By electron microscopy,...

journal_title：Archives of pathology & laboratory medicine

authors： Okanoue T,Burbige EJ,French SW

更新日期：1983-09-01 00:00:00

abstract：:We describe a young patient with no known family history of cancer who presented at 18 months with 2 advanced primary tumors, choroid plexus carcinoma and adrenal cortical carcinoma. Immunohistochemical studies demonstrated high levels of nuclear p53 protein expression in both tumors, as well as in the adjacent normal...

journal_title：Archives of pathology & laboratory medicine

authors： Wang L,Cornford ME

更新日期：2002-01-01 00:00:00

abstract：:Two alpha-fucose-binding lectins, Ulex europaeus agglutinin I (UEA I) and Lotus tetragonolobus agglutinin, were employed to compare and contrast the distribution of fucosubstance in normal human kidneys and a variety of renal tumors. The study employed a total of 31 kidneys surgically removed for the presence of a var...

journal_title：Archives of pathology & laboratory medicine

authors： Hennigar RA,Sens DA,Othersen HB,Garvin AJ

更新日期：1988-09-01 00:00:00