Some characteristics of academic departments of pathology in the United States. Implications for training of academic pathologists.

abstract：:Invasive lobular carcinoma of the breast is a relatively common diagnosis. However, other carcinomatous as well as noncarcinomatous neoplasms, either primary or metastatic to the breast, may mimic invasive lobular carcinoma. As treatment may differ, establishing the correct diagnosis is paramount to providing the appr...

journal_title：Archives of pathology & laboratory medicine

authors： Ishikawa MK,Pinsky RW,Smith LB,Jorns JM

更新日期：2015-10-01 00:00:00

abstract：CONTEXT.—:Repair is a challenging diagnosis and a significant source of false-positive (FP) interpretations in cervical cytology. No large-scale study of performance of repair in the liquid-based era has been performed. OBJECTIVE.—:To evaluate the performance of repair in the College of American Pathologists Pap Educa...

journal_title：Archives of pathology & laboratory medicine

authors： Staats PN,Souers RJ,Nunez AL,Li Z,Kurtycz DFI,Goodrich K,Witt BL,Davey DD,Booth CN

更新日期：2019-11-22 00:00:00

abstract：:In this article, we review prostatic lymphomas and discuss the differential diagnosis of high-grade malignant neoplasms of the prostate. We illustrate this with a case of a 46-year-old man seen with lower urinary tract obstruction who had diffuse involvement by a high-grade malignancy on prostate biopsy. Morphologic e...

journal_title：Archives of pathology & laboratory medicine

authors： Warrick JI,Owens SR,Tomlins SA

更新日期：2014-10-01 00:00:00

abstract：CONTEXT:The College of American Pathologists periodically surveys laboratories to determine changes in cytopathology practices. We report the results of a 2011 gynecologic cytology survey. OBJECTIVE:To provide a cross-sectional survey of gynecologic cytology practices in 2010. DESIGN:In 2011, a survey was sent to 160...

journal_title：Archives of pathology & laboratory medicine

authors： Crothers BA,Darragh TM,Tambouret RH,Nayar R,Barkan GA,Zhao C,Booth CN,Padmanabhan V,Tabatabai ZL,Souers RJ,Thomas N,Wilbur DC,Moriarty AT

更新日期：2016-01-01 00:00:00

abstract：CONTEXT:Recent advances in understanding the molecular basis of melanoma have resulted in development of fluorescence in situ hybridization (FISH) protocols designed to detect genetic abnormalities discriminating melanoma from nevi. The most extensively studied is a 4-probe multicolor FISH probe panel targeting chromos...

journal_title：Archives of pathology & laboratory medicine

authors： Gerami P,Zembowicz A

更新日期：2011-07-01 00:00:00

abstract：CONTEXT:Genomic medicine is revolutionizing patient care. Physicians in areas as diverse as oncology, obstetrics, and infectious disease have begun using next-generation sequencing assays as standard diagnostic tools. OBJECTIVE:To review the role of pathologists in genomic testing as well as current educational progra...

journal_title：Archives of pathology & laboratory medicine

authors： Haspel RL,Olsen RJ,Berry A,Hill CE,Pfeifer JD,Schrijver I,Kaul KL

更新日期：2014-04-01 00:00:00

abstract：CONTEXT:- Nonuterine high-grade serous carcinomas (HGSCs) are believed to arise most often from precursors in the fallopian tube referred to as serous tubal intraepithelial carcinomas (STICs). A designation of tubal origin has been suggested for all cases of nonuterine HGSC if a STIC is identified. OBJECTIVE:- To high...

journal_title：Archives of pathology & laboratory medicine

authors： Singh R,Cho KR

更新日期：2017-10-01 00:00:00

abstract：:The objective of this study was to evaluate conjunctival nevi for p53 gene mutations. We studied 11 conjunctival nevi by immunohistochemistry with the DO7 monoclonal p53 antibody as well as the cell proliferation marker, MIB1. Of the 11 cases, 2 were negative, 2 had less than 1%, and 7 had more than 2% p53 immunoposit...

journal_title：Archives of pathology & laboratory medicine

authors： Jay V,Ho M,Hunter W,Rootman D,Zielenska M

更新日期：1996-04-01 00:00:00

abstract：CONTEXT:Recent studies have uncovered a number of possible mechanisms by which prostate cancers can become resistant to systemic androgen deprivation, most involving androgen-independent reactivation of the androgen receptor. Genome-wide expression analysis with microarrays has identified a wide array of genes that are...

journal_title：Archives of pathology & laboratory medicine

authors： Mackinnon AC,Yan BC,Joseph LJ,Al-Ahmadie HA

更新日期：2009-07-01 00:00:00

abstract：CONTEXT:Turnaround time (TAT) for large or complex surgical pathology specimens is an indicator of efficiency in anatomic pathology and may affect coordination of patient care. OBJECTIVE:To establish benchmarks for TAT and to identify practice characteristics that may influence TAT. DESIGN:Participants in a 2012 Q-Pr...

journal_title：Archives of pathology & laboratory medicine

authors： Volmar KE,Idowu MO,Souers RJ,Karcher DS,Nakhleh RE

更新日期：2015-02-01 00:00:00

abstract：:A 50-year-old man presented with a lung mass in the left upper lobe, which was shown by electron microscopy to be a thymoma. There was no evidence of a mediastinal mass. The lymphocytes of the tumor reacted with monoclonal antibody T101, a pan T-cell marker, and with OKT8. B1 and B2 surface antigens characteristic of ...

journal_title：Archives of pathology & laboratory medicine

authors： Green WR,Pressoir R,Gumbs RV,Warner O,Naab T,Qayumi M

更新日期：1987-11-01 00:00:00

abstract：CONTEXT:Myofibroblastic proliferations of the urinary bladder, which share some similarities with nodular fasciitis, were first reported in 1980. Since then, they have had several designations, the most frequently used being inflammatory myofibroblastic tumor. Based on both histopathologic and prognostic grounds, some ...

journal_title：Archives of pathology & laboratory medicine

authors： Alquati S,Gira FA,Bartoli V,Contini S,Corradi D

更新日期：2013-08-01 00:00:00

abstract：:von Hippel-Lindau (VHL) disease is an autosomal dominant disorder caused by heterozygous mutations in the VHL tumor suppressor gene that is characterized by the occurrence of multiple endocrine and nonendocrine lesions. This review focuses on the endocrine manifestations of VHL disease. Pancreatic neuroendocrine proli...

journal_title：Archives of pathology & laboratory medicine

authors： Cassol C,Mete O

更新日期：2015-02-01 00:00:00

abstract：:Progressive sclerosing orbital pseudotumors are a subset of usually primary and localized idiopathic fibroinflammatory disorders. We report on a 66-year-old man who developed this condition along the facial tissue planes with extension into the orbit and preferential involvement of the periorbital membrane. Fibrocolla...

journal_title：Archives of pathology & laboratory medicine

authors： Mehta M,Jakobiec F,Fay A

更新日期：2009-08-01 00:00:00

abstract：:A peroxidase--antiperoxidase technique for S100 protein has been applied to 122 breast lesions from 122 patients. These included 35 cases of fibrocystic disease, 16 cases of sclerosing adenosis, 24 cases of papilloma and papillomatosis, 43 intraduct carcinomas, and four intralobular carcinomas. In fibrocystic disease,...

journal_title：Archives of pathology & laboratory medicine

authors： Egan MJ,Newman J,Crocker J,Collard M

更新日期：1987-01-01 00:00:00

abstract：CONTEXT:Digital viewing of histologic images is moving from presentations and publications to incorporation into the daily work of practicing pathologists. Many technologic limitations have been overcome recently, which should make widespread adoption more practical. The task now is for pathologists to become actively ...

journal_title：Archives of pathology & laboratory medicine

authors： Hedvat CV

更新日期：2010-11-01 00:00:00

abstract：:Amplification of the neu oncogene and overexpression of its product was found to be a potential marker for aggressive biological behavior in breast cancer. However, the expression of the neu oncoprotein in normal breast ducts and myoepithelial cells has also been demonstrated. Hence, we examined normal salivary gland ...

journal_title：Archives of pathology & laboratory medicine

authors： Kahn HJ,Hanna W,Auger M,Andrulis I

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Metanephric adenoma is a very rare benign renal tumor; only 80 well-documented cases have been reported to date. We have seen several renal tumors that were originally incorrectly diagnosed as metanephric adenoma. DESIGN:We present 3 unusual renal tumors (2 primary and 1 metastatic), each of which illustrat...

journal_title：Archives of pathology & laboratory medicine

authors： Pins MR,Jones EC,Martul EV,Kamat BR,Umlas J,Renshaw AA

更新日期：1999-05-01 00:00:00

abstract：CONTEXT:Sclerosing hemangioma of the lung is well characterized histologically, but the line of differentiation expressed by the tumor cells has been unclear. Despite the implication by its name of a vascular neoplasm, sclerosing hemangioma is considered by most authorities to be an epithelial tumor, possibly related t...

journal_title：Archives of pathology & laboratory medicine

authors： Illei PB,Rosai J,Klimstra DS

更新日期：2001-10-01 00:00:00

abstract：:We evaluated the utility of a monoclonal antibody that recognizes Pneumocystis carinii as a diagnostic tool in specimens of bronchoalveolar lavage fluid and sputum from patients in whom a diagnosis of P carinii pneumonia was being considered. In addition to routine processing for diagnosis by morphologic recognition o...

journal_title：Archives of pathology & laboratory medicine

authors： Blumenfeld W,Kovacs JA

更新日期：1988-12-01 00:00:00

abstract：:Keratin and carcinoembryonic antigen immunoperoxidase staining were applied to lung cancer cells in paraffin sections of cell blocks from sputa and bronchial washings. The results correlate well with cytologic diagnosis. The large cell carcinomas are nonreactive with both antibodies. ...

journal_title：Archives of pathology & laboratory medicine

authors： Lyubsky S,Thorn R

更新日期：1989-01-01 00:00:00

abstract：CONTEXT:Pediatric myelodysplastic syndromes (MDSs) are uncommon disorders, which may be difficult to diagnose, particularly in the absence of increased blasts. Pediatric MDSs have several unique features including their association with inherited/constitutional disorders in approximately one third of patients. The clas...

journal_title：Archives of pathology & laboratory medicine

authors： Elghetany MT

更新日期：2007-07-01 00:00:00

abstract：CONTEXT:Clinical laboratory specimens may be rejected as unsuitable for analysis for a variety of reasons and specimen rejection may have significant clinical consequences. OBJECTIVE:To quantify the clinical consequences of specimen rejection and determine the impact of laboratories' policies and practices on these co...

journal_title：Archives of pathology & laboratory medicine

authors： Karcher DS,Lehman CM

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:This review focuses on commercial and in-house-developed reverse-transcription polymerase chain reaction (RT-PCR) assays used for the detection of enteroviral infections. In addition to providing details on the performance of RT-PCR, its specificity, and sensitivity, the clinical utility of this diagnostic me...

journal_title：Archives of pathology & laboratory medicine

authors： Romero JR

更新日期：1999-12-01 00:00:00

abstract：:An unusual case of primary angiitis of the central nervous system associated with Hodgkin's disease in a 55-year-old-man is reported. After a 10-month history of acute transverse myelitis, the patient was diagnosed as having nodular sclerosing-type Hodgkin's disease involving the retroperitoneal lymph nodes. The patie...

journal_title：Archives of pathology & laboratory medicine

authors： Yuen RW,Johnson PC

更新日期：1996-06-01 00:00:00

abstract：:A 55-year-old woman developed symptoms suggestive of hepatitis 12 weeks after first receiving methyldopa for hypertension. Liver biopsy showed chronic aggressive hepatitis with subacute hepatic necrosis. Methyldopa was discontinued, but after exhibiting transient clinical improvement, the patient's condition progressi...

journal_title：Archives of pathology & laboratory medicine

authors： Thomas E,Bhuta S,Rosenthal WS

更新日期：1976-03-01 00:00:00

abstract：CONTEXT:The clinical introduction of new oral anticoagulants (NOACs) has stimulated the development of tests to quantify the effects of these drugs and manage complications associated with their use. Until recently, the only treatment choices for the prevention of venous thromboembolism in orthopedic surgical patients,...

journal_title：Archives of pathology & laboratory medicine

authors： Dias JD,Norem K,Doorneweerd DD,Thurer RL,Popovsky MA,Omert LA

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVE:The pathogenesis of appendicitis remains poorly understood. However, there is increasing evidence of involvement of the enteric nervous system in immune regulation and in inflammatory responses. This study was set up to characterize the status of the enteric nervous system in normal and in inflamed appendixes...

journal_title：Archives of pathology & laboratory medicine

authors： Xiong S,Puri P,Nemeth L,O'Briain DS,Reen DJ

更新日期：2000-10-01 00:00:00

abstract：CONTEXT:Perineural invasion and vascular invasion may be adverse prognostic factors in patients with oral cavity squamous cell carcinoma. However, the incidence of perineural and vascular invasion varies in the literature, and the use of immunohistochemistry to enhance their detection has not been evaluated in oral cav...

journal_title：Archives of pathology & laboratory medicine

authors： Kurtz KA,Hoffman HT,Zimmerman MB,Robinson RA

更新日期：2005-03-01 00:00:00

abstract：CONTEXT:Myelodysplastic syndromes (MDSs) are clonal stem cell diseases characterized by ineffective hematopoiesis, multilineage dysplasia, and peripheral cytopenias with normocellular or hypercellular marrow. They represent a heterogeneous group of disorders with a varied spectrum of clinical, morphologic, biologic, an...

journal_title：Archives of pathology & laboratory medicine

authors： Nishino HT,Chang CC

更新日期：2005-10-01 00:00:00