Early graft dysfunction after liver transplantation.


:Liver transplantation has become the treatment of choice for fulminant hepatic failure and end-stage liver diseases. Several factors have been described to be predictors of graft function. Since early graft dysfunction dramatically influences graft and patient outcomes after liver transplantation, prevention of this event is mandatory. Donor-, procurement-, operative- and recipient-related factors influence the development of graft dysfunction. We have presented herein a review of the impact of these factors on graft dysfunction.


Transplant Proc


Briceño J,Ciria R




Has Abstract


2010-03-01 00:00:00














  • Interleukin-2 profiles shortly after tacrolimus conversion from a twice-daily to once-daily regimen.

    abstract::A number of studies have indicated that kidney recipients can be safely converted from the twice-daily formulation (Tac-T) to the same dose of a once-daily tacrolimus (TAC) regimen (Tac-O) based upon monitoring of renal function. Conversion from Tac-T to Tac-O is commonly followed by a reduction in Tac trough levels, ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Meçule A,Tinti F,Bachetoni A,Poli L,D'Alessandro M,Alessandri C,Umbro I,Nofroni I,Berloco PB,Mitterhofer AP

    更新日期:2011-05-01 00:00:00

  • A prospective cross-over study comparing the pharmacokinetics of cyclosporine A and its metabolites after oral versus short-time intravenous cyclosporine A administration in pre-heart transplant patients.

    abstract::Sometimes intravenous administration of cyclosporine (CsA) is essential before oral administration is possible. There are only a few reports available on the interindividual variability of CsA metabolism and different metabolite pattern depending on intravenous versus oral administration of CsA in heart transplant (HT...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Lehle K,Kirchner GI,Rupprecht L,Gruber M,Birnbaum DE,Schmid FX,Preuner JG

    更新日期:2007-12-01 00:00:00

  • Paradoxical depression in renal transplant recipients.

    abstract::Paradoxical depression occurs despite a completely successful transplantation without tissue rejection or other medical complications. In this study, the occurrence of paradoxical depression was retrospectively investigated among 1,139 Japanese successful renal transplant recipients January 1997 through September 2006...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Sugawara H,Nishimura K,Kobayashi S,Ishida H,Tanabe K,Ishigooka J

    更新日期:2008-12-01 00:00:00

  • Elevated tacrolimus levels associated with intravenous azithromycin and ceftriaxone: a case report.

    abstract::Drug interactions are a common occurrence with calcineurin inhibitors. We describe the case of a heart transplant recipient who developed increased tacrolimus blood levels after the administration of intravenous azithromycin and ceftriaxone. Tacrolimus levels decreased after the discontinuation of ceftriaxone and swit...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Shullo MA,Schonder K,Teuteberg JJ

    更新日期:2010-06-01 00:00:00

  • Color Doppler findings in transplanted kidneys and remnant kidneys of donors 6 to 12 months after kidney transplantation.

    abstract:OBJECTIVES:Ultrasonography and color Doppler have been used extensively in the evaluation of transplanted kidney. The aim of this study was evaluation and comparison of color Doppler sonography findings in the remnant kidney of living donors and the transplanted kidney at 6 to 12 months after kidney transplantation. M...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Khosroshahi HT,Tarzamni MK,Gojazadeh M,Bahluli A

    更新日期:2007-05-01 00:00:00

  • Nuclear translocation of SMAD3 may enhance the TGF-beta/SMADS pathway in high glucose circumstances.

    abstract:OBJECTIVES:Posttransplant diabetes mellitus is one of the most frequent complications after kidney transplantation. It is considered to be one cause of chronic allograft nephropathy. This study sought to investigate the effects of high glucose on the expression and nuclear translocation of Smad3, which is an important ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Li Q,Ye F,Shi Y,Zhang L,Wang W,Tu Z,Qiu J,Wang J,Li S,Bu H,Li Y

    更新日期:2006-09-01 00:00:00

  • Using elderly donors in liver transplantation.

    abstract:AIM:Elderly donors are half of the grafts available in our center for liver transplantation. We retrospectively investigated their characteristics, outcomes, and variables related to graft failure. MATERIAL AND METHODS:From 1996 to 2003, 540 (46.4%) of 1163 donors were older than 60 years of age and 236 grafts (43.4%)...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Grazi GL,Ravaioli M,Zanello M,Ercolani G,Cescon M,Varotti G,Del Gaudio M,Vetrone G,Lauro A,Ramacciato G,Pinna AD

    更新日期:2005-07-01 00:00:00

  • Early microchimerism in peripheral blood following kidney transplantation.

    abstract:BACKGROUND:The role of microchimerism found in the peripheral blood of renal transplant recipients remains a matter of debate. We assessed the frequency of microchimerism after kidney transplantation and examined its influence on clinical courses over a 12-month follow-up period. PATIENTS AND METHODS:Ten single-kidney...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Kishikawa H,Kinoshita T,Yonemoto S,Kawamura M,Nakazawa S,Ueda N,Hirai T,Nishimura K,Hashimoto M,Ichikawa Y

    更新日期:2014-01-01 00:00:00

  • Compound Effect of Kidney Donor Profile Index and Cold Ischemic Time on 1-Year Kidney Transplant Recipient Outcomes.

    abstract:OBJECTIVE:Kidney Donor Profile Index (KDPI) and cold ischemic time (CIT) independently influence recipient outcomes after kidney transplantation; however, the compound effect of these variables on posttransplant outcomes is unknown. DESIGN:The Scientific Registry of Transplant Recipients database of deceased-donor kid...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Kutzler HL,Martin ST,O'Sullivan DM,Rochon C

    更新日期:2019-12-01 00:00:00

  • Association of the metabolic syndrome and long-term renal function in kidney donors.

    abstract:BACKGROUND:Metabolic syndrome (MetS) may represent risk factor for long-term renal function of kidneys from living donors. The aim of this study was to evaluate the impact of MetS on renal function in donors. METHODS:Data regarding the presence or absence of MetS and renal function, as assessed by estimated glomerular...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Cuevas-Ramos D,Almeda-Valdés P,Arvizu M,Mata J,Morales-Buenrostro LE,Gabilondo B,Vilatobá M,Correa-Rotter R,Gabilondo-Navarro F,Mehta R,Aguilar-Salinas CA,Alberú J,Gómez-Pérez FJ

    更新日期:2011-06-01 00:00:00

  • Effects of polyethylene glycol and hydroxyethyl starch in University of Wisconsin preservation solution on human red blood cell aggregation and viscosity.

    abstract::University of Wisconsin (UW) preservation solution is considered an effective flush and cold storage liquid. However, recent studies have provided evidence of the hyperaggregating effect on human red blood cells (RBC) of hydroxyethyl starch (HES), one of the components of the UW solution. In contrast, preservation sol...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Mosbah IB,Franco-Gou R,Abdennebi HB,Hernandez R,Escolar G,Saidane D,Rosello-Catafau J,Peralta C

    更新日期:2006-06-01 00:00:00

  • Expression of CD158b on peripheral blood lymphocytic cell after kidney transplantation.

    abstract:OBJECTIVE:To investigate the expression of CD158b on peripheral blood lymphocytes after kidney transplantation. METHODS:Sixty two kidney transplant patients were divided into two groups (normal group and rejection group) according to pathologic results and clinical situation. Blood samples were assessed for percentage...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Kang N,Guan D,Xing N,Xia C

    更新日期:2005-03-01 00:00:00

  • Visfatin, a new adipocytokine, is predominantly related to inflammation/endothelial damage in kidney allograft recipients.

    abstract::Visfatin, a ubiquitous adipokine, was first described in 2005. It was found to be selectively up-regulated in the adipose tissue and to have insulin-mimetic effects. It has been reported that visfatin is associated with endothelial damage in chronic kidney disease. We investigated plasma visfatin levels (using commerc...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Malyszko J,Malyszko JS,Mysliwiec M

    更新日期:2009-01-01 00:00:00

  • Successful Ultrasound-Guided Percutaneous Drainage of Multiple Splenic Abscesses in a Kidney Transplant Patient With Encapsulated Sclerosing Peritonitis: A Case Report.

    abstract::Differential diagnosis of post-transplant infections should include rare/uncommon foci and pathogens. We present a rare case of life-threatening infection, a splenic abscess in a 53-year-old woman who was transplanted with a cadaveric kidney 5 months previously. The patient was admitted to our clinic with chills, shiv...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Tuğcu M,Ruhi Ç,Boynueğri B,Kasapoğlu U,Can Ö,Kiliçoğlu G,Şahin G,Titiz M

    更新日期:2015-06-01 00:00:00

  • Prevalence of anemia in renal transplant patients: results from MOST, an observational trial.

    abstract:INTRODUCTION:Anemia is one of the most common complications of chronic renal disease. However, the incidence or prevalence of anemia in kidney transplant recipients has not been well studied. The aim of this study was to assess the prevalence of anemia in renal transplant in early and late posttransplant period and the...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Fernández Fresnedo G,Palomar R,Rodrigo E,Ruiz JC,de Francisco AL,Cotorruelo JG,Arias M

    更新日期:2005-11-01 00:00:00

  • Duct-to-duct biliary reconstruction in pediatric liver transplantation: one center's results.

    abstract::In pediatric liver transplantation, both for cadaveric and living-related patients, the Roux-en-Y hepaticojejunostomy is often preferable to biliary reconstruction. Duct-to-duct biliary reconstruction in pediatric patients has been utilized only in a limited numbers of studies. Here, we retrospectively review our expe...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Haberal M,Sevmis S,Emiroglu R,Karakayali H,Arslan G

    更新日期:2007-05-01 00:00:00

  • Hepatitis B reactivation in a renal transplant patient due to a surface antigen mutant strain: a case report.

    abstract:INTRODUCTION:Reactivation of hepatitis B virus (HBV) is a complication of immunosuppressive treatment in patients with a history of HBV exposure. CASE PRESENTATION:Herein we have reported a case of reactivation after renal transplantation in a 52-year-old male chronic HBV carrier who was treated with hepatitis B immun...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Fylaktou A,Daoudaki M,Dimou V,Sianou E,Papaventsis D,Mavrovouniotis I,Fouzas I,Papanikolaou V

    更新日期:2012-11-01 00:00:00

  • Impact of mycophenolate mofetil dose posttransplantation on 12-month renal function: analysis of the MOST database.

    abstract:INTRODUCTION:Mycophenolate mofetil (MMF) has greatly reduced the risk of acute rejection episodes (ARE) after renal transplantation, but dose reductions/withdrawals could jeopardize long-term results. METHODS:The MOST database of "de novo" patients treated with MMF at month 1 and functioning grafts at month 12 were di...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章,多中心研究


    authors: Salvadori M,Bock A,Chapman J,Dussol B,Fritsche L,Kliem V,Lebranchu Y,Oppenheimer F,Pohanka E,Tufveson G,Rosati A,Puig X,Corbetta G,MOST International Study Group.

    更新日期:2005-07-01 00:00:00

  • The effect of later change or modulation of immunosuppression on long-term renal transplant results.

    abstract::Proper maintenance of immunosuppression is required to achieve long-term graft survival. The aim of this study was to evaluate the effect of change or modulation of an immunosuppressive regimen (IR) on graft survival during the posttransplant period in patients undergoing kidney transplantation. A total of 1164 patien...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Lee JJ,Kim MS,Kim YS,Joo DJ,Ju MK,Kim HJ,Lee JE,Kim SI,Huh KH

    更新日期:2010-12-01 00:00:00

  • Cytomegalovirus replication and "herpesvirus burden" as risk factor of cardiovascular events in the first year after renal transplantation.

    abstract::Cytomegalovirus (CMV) infection alone or in combination with other pathogens ("pathogen burden") has been postulated as a factor producing arteriosclerosis in some solid organ transplant recipients. The aim of this study was to assess whether the patients with CMV replication and/or "herpesvirus burden" experienced a ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Gómez E,Laurés A,Baltar JM,Melón S,Díez B,de Oña M

    更新日期:2005-11-01 00:00:00

  • Homocysteine-lowering therapy and carotid intima-media thickness in renal transplant recipients.

    abstract::The aim of this study was to document, in hyperhomocysteinemic renal transplant recipients, the effect of vitamin supplementation on carotid intima-media thickness (cIMT). Fifty-six hyperhomocysteinemic stable renal transplant recipients were randomly assigned to either vitamin supplementation (group A) or placebo tre...

    journal_title:Transplantation proceedings

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Marcucci R,Zanazzi M,Bertoni E,Rosati A,Fedi S,Lenti M,Prisco D,Castellani S,Abbate R,Salvadori M

    更新日期:2005-07-01 00:00:00

  • Effect of Donor- and Recipient-Related Factors on Arterial Resistance Index After Kidney Transplant.

    abstract:BACKGROUND:The assessment of color Doppler resistance index (RI) of the intra-renal arteries has been shown to be a good predictor of short-term and long-term graft survival after kidney transplant. In this study, we investigated the influence of donor- and recipient-related factors on RI evaluated early after kidney t...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Saracino A,Santarsia G

    更新日期:2015-09-01 00:00:00

  • Heterogeneity of human pancreata in perspective of the isolation of the islets of langerhans.

    abstract::The success of human islet isolation is hampered by the varied and unpredictable outcomes of the islet isolation procedure. Pancreata which meet well-defined criteria are no guarantee for success. Interindividual variations may contribute to the differences in isolation outcomes. The present study examined several str...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Töns HA,Terpstra OT,Bouwman E

    更新日期:2008-03-01 00:00:00

  • Pancreata from pediatric donors restore insulin independence in adult insulin-dependent diabetes mellitus recipients.

    abstract:CONTEXT:The use of pediatric donors can increase the number of donors available for pancreas transplantation. AIM:The aim of this study was to verify if pancreas transplantation from pediatric donors is as effective as transplantation from adult donors to restore metabolic control in type 1 diabetic patients. MATERIA...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Socci C,Orsenigo E,Santagostino I,Caumo A,Caldara R,Parolini D,Aldrighetti L,Castoldi R,Frasson M,Carvello M,Ghirardelli L,Secchi A,Di Carlo V,Staudacher C

    更新日期:2010-07-01 00:00:00

  • Thrombomodulin administration attenuates ischemia-reperfusion injury of the remnant liver after 70% hepatectomy in rats: simulated model of small-for-size graft in living donor liver transplantation.

    abstract:BACKGROUND:Hepatic ischemia-reperfusion injury (IRI) is a serious complication affecting liver function and postoperative course after liver transplantation. Thrombomodulin (TM) has been known to have anticoagulant and anti-inflammatory activities exerting a cytoprotective effect. We evaluated the cytoprotective effect...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Tanemura A,Kuriyama N,Azumi Y,Ohsawa I,Kishiwada M,Mizuno S,Usui M,Sakurai H,Tabata M,Isaji S

    更新日期:2014-05-01 00:00:00

  • Mechanism of Premature Apoptosis in CD1d-Restricted Natural Killier T Cells From Human Peripheral Blood During the Induction of Proliferation In Vitro.

    abstract:OBJECTIVE:A preliminary investigation on the proliferation and cultivation process of natural killer T cells (NKT) was carried out. We provide reference data for future NKT-related research and development. METHODS:Peripheral blood mononuclear cells (PBMCs) were isolated from healthy people and were induced by α-galac...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Gao L,Fan Y,Yang Y,Xie R,Yang J,Chen Z

    更新日期:2018-06-01 00:00:00

  • Deceased Donor Liver Transplantation in India in the COVID-19 Era: Current Scenario and Future Perspectives.

    abstract::Coronavirus disease 2019 (COVID-19) has been recently declared a global pandemic. As of June 5, 2020, over 75,000 cases have been reported with nearly 2500 deaths in India alone. COVID-19 has severely impacted deceased donor liver transplant (DDLT) programs throughout the world. Acceptance of deceased liver donors has...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Pahari H,Shellagi N,Nath B

    更新日期:2020-11-01 00:00:00

  • Retransplantation for end-stage liver disease: a single-center Asian experience.

    abstract::Liver retransplantation carries a significantly higher morbidity and mortality compared with patients after single transplantations. The aim of this study was to review our outcomes in liver retransplantations. From February 1984 to February 2007, 409 liver transplantations were performed on 396 patients, including 13...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Sun CK,Chen CL,Concejero AM,Wang CC,Wang SH,Liu YW,Yang CH,Yong CC

    更新日期:2008-10-01 00:00:00

  • Impact of ABO-incompatible donor on early and late outcome of hematopoietic stem cell transplantation.

    abstract::ABO incompatibility is not a barrier to allogeneic hematopoietic stem cell transplantation (HSCT). However, the impact of an ABO mismatch on the outcome of the HSCT remains controversial. We analyzed whether ABO incompatibility leads to an increased risk of early/late complications, mortality, or increased transfusion...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Ozkurt ZN,Yegin ZA,Yenicesu I,Aki SZ,Yagci M,Sucak GT

    更新日期:2009-11-01 00:00:00

  • Curcumin Attenuates Hemorrhagic Shock and Blood Replenish Resuscitation-induced Impairment of Pulmonary Barrier Function by Increasing SIRT1 and Reducing Malondialdehyde and TNF-α Contents and Neutrophil Infiltration in Lung in a Dose-Dependent Fashion.

    abstract:OBJECTIVES:Acute lung injury (ALI) is a critical complication subsequent to hemorrhage shock and resuscitation (HSR) that frequently leads to multiple organ failure. Collective evidence suggested that the activation of pulmonary nicotinamide adenine dinucleotide-dependent deacetylase sirtuin-1 (SIRT1) plays a critical ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Yu-Wung Yeh D,Wang JJ

    更新日期:2020-01-01 00:00:00