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Uruguayan experience with cryopreserved arterial homografts.

Abstract：

INTRODUCTION:We analyzed the Uruguayan experience with cryopreserved arterial homografts. We studied 55 medical records in the period from June 9, 2000 to April 7, 2007, including 41 from males and 14 from females, ranging from 36-78 years of age. The clinical indications were as follows: Group 1, revascularization of infrainguinal atherosclerotic occlusive disease by bypass due to the lack of availability of a suitable vein (n = 35); Group 2, substitution of an infected prosthetic grafts (n = 15); and Group 3, arteriovenous fistula (AVF) after failure of previous prosthetic loops by repeated thrombosis and/or infection in the absence of a vein (n = 5). RESULTS:Among Group 1, primary and secondary patency rates were 61% and 71%, respectively at 1 year with 15 complications, 3 infections, 8 thromboses, 2 aneurysms, 1 homograft degradation, and 1 death related to surgery. Among Group 2, the primary and secondary patency rates were 71% and 79%, respectively, at 1 year with 6 patients experiencing complications. Group 3 did not have complications with a primary patency rate of 67% at 1 year. CONCLUSIONS:The use of cryopreserved arterial homografts is a valid, accessible, and safe alternative in complicated vascular situations. In our country, it is a technology to consider for patients with critical limb ischemia, when the risk of a major amputation is high and it is not possible to have a suitable vein or prosthetic bypass. It can be an excellent alternative for the substitution of infected synthetic bypasses, especially to substitute in situ for an infected aortic graft.

journal_name

Transplant Proc

journal_title

Transplantation proceedings

authors

Esperón A,Kamaid E,Diamant M,Campos HP,Del Carmen Saldías M,Icasuriaga A,Varela C,Delgado D,Alvarez I

doi

10.1016/j.transproceed.2009.09.006

subject

Has Abstract

pub_date

2009-10-01 00:00:00

pages

3500-4

issue

8

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(09)01254-8

journal_volume

41

pub_type

杂志文章

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