Administration of ondansetron is associated with lethal outcome.

Abstract:

:We report here the case of a child with a known muscular abnormality and susceptibility to malignant hyperthermia who abruptly died after receiving a therapeutic dose of ondansetron. Also, we discuss the pharmacodynamic relationship of ondansetron to malignant hyperthermia in a susceptible host.

journal_name

Pediatrics

journal_title

Pediatrics

authors

Gener B,Burns JM,Griffin S,Boyer EW

doi

10.1542/peds.2009-2795

subject

Has Abstract

pub_date

2010-06-01 00:00:00

pages

e1514-7

issue

6

eissn

0031-4005

issn

1098-4275

pii

peds.2009-2795

journal_volume

125

pub_type

杂志文章
  • Pediatric advance care planning: a systematic review.

    abstract:BACKGROUND AND OBJECTIVES:Advance care planning (ACP) is increasingly regarded as the gold standard in the care of patients with life-limiting illnesses. Research has focused on adults, but ACP is also being practiced in pediatrics. We conducted a systematic review on empirical literature on pediatric ACP (pACP) to ass...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.2012-2394

    authors: Lotz JD,Jox RJ,Borasio GD,Führer M

    更新日期:2013-03-01 00:00:00

  • Varicella zoster virus meningitis in a previously immunized child.

    abstract::We are reporting a previously well 5-year-old child with varicella-zoster meningitis who had a history of a previous immunization against varicella. This child also developed a transient sensorineural hearing loss. The child was treated with acyclovir and made a full recovery. ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.114.2.e273

    authors: Schwab J,Ryan M

    更新日期:2004-08-01 00:00:00

  • Mental health problems and overweight in a nationally representative sample of adolescents: effects of race and ethnicity.

    abstract:OBJECTIVES:In this study we examined the relation between mental health problems and weight in a population-based study of youth aged 12 to 17 years and whether the association between mental health problems and weight is moderated by race and ethnicity. METHODS:We used 2003 National Survey on Children's Health data. ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2008-0687

    authors: BeLue R,Francis LA,Colaco B

    更新日期:2009-02-01 00:00:00

  • Feasibility and preliminary outcomes of a scalable, community-based treatment of childhood obesity.

    abstract:OBJECTIVE:Clinic-based treatments of childhood obesity are effective but typically have limited reach and are costly. In this study, we evaluated the effects of a scalable weight management program for children and teenagers. METHODS:Participants were 155 children and their parent/guardian. Children had a mean ± SD ag...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章

    doi:10.1542/peds.2012-0344

    authors: Foster GD,Sundal D,McDermott C,Jelalian E,Lent MR,Vojta D

    更新日期:2012-10-01 00:00:00

  • A comparative study of the behavior of Greek neonates.

    abstract::Three groups of 30 Greek neonates each (an adoptive group from the Metera orphanage, a lower-class group, and a middle-class group) were evaluated at days 1, 5, and 10 after birth using a behavioral scale of 21 items and a neurologic evaluation of 16 items. Behaviors were examined for group differences and group-by-ag...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Brazelton TB,Tryphonopoulou Y,Lester BM

    更新日期:1979-02-01 00:00:00

  • Effects of waterbed flotation on premature infants: A pilot study.

    abstract::Two types of waterbeds were developed to impart compensatory vestibular-proprioceptive stimulation to premature infants. Twenty-one infants ranging in gestational age from 27 to 34 weeks and birthweights from 1,050 to 1,920 gm were included in this pilot study. Assignment to experimental and control groups was made by...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Korner AF,Kraemer HC,Haffner ME,Cosper LM

    更新日期:1975-09-01 00:00:00

  • A note on interdisciplinary research in developmental/behavioral pediatrics/psychology.

    abstract::In sum, we have offered a few observations about the practice of interdisciplinary research. Now, in addition to our rather specific suggestions, we want to add a few general comments about the interactions of professionals who are actually involved in interdisciplinary research. Collaboration between physicians and p...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Ellison PH,Kopp CB

    更新日期:1985-05-01 00:00:00

  • Acceptability of Family-Centered Advanced Care Planning for Adolescents With HIV.

    abstract:BACKGROUND AND OBJECTIVE:Small pilot studies support the appropriateness of engaging adolescents with chronic or life-limiting illnesses in pediatric advance care planning (pACP). We do not yet know if pACP is acceptable, feasible, and worthwhile, even if emotionally intense, in a fully powered randomized controlled tr...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1542/peds.2016-1854

    authors: Dallas RH,Kimmel A,Wilkins ML,Rana S,Garcia A,Cheng YI,Wang J,Lyon ME,Adolescent Palliative Care Consortium.

    更新日期:2016-12-01 00:00:00

  • The infant development, environment, and lifestyle study: effects of prenatal methamphetamine exposure, polydrug exposure, and poverty on intrauterine growth.

    abstract:OBJECTIVE:Methamphetamine use among pregnant women is an increasing problem in the United States. Effects of methamphetamine use during pregnancy on fetal growth have not been reported in large, prospective studies. We examined the neonatal growth effects of prenatal methamphetamine exposure in the multicenter, longitu...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1542/peds.2005-2564

    authors: Smith LM,LaGasse LL,Derauf C,Grant P,Shah R,Arria A,Huestis M,Haning W,Strauss A,Della Grotta S,Liu J,Lester BM

    更新日期:2006-09-01 00:00:00

  • Fruit Juice in Infants, Children, and Adolescents: Current Recommendations.

    abstract::Historically, fruit juice was recommended by pediatricians as a source of vitamin C and as an extra source of water for healthy infants and young children as their diets expanded to include solid foods with higher renal solute load. It was also sometimes recommended for children with constipation. Fruit juice is marke...

    journal_title:Pediatrics

    pub_type: 指南,杂志文章

    doi:10.1542/peds.2017-0967

    authors: Heyman MB,Abrams SA,SECTION ON GASTROENTEROLOGY, HEPATOLOGY, AND NUTRITION.,COMMITTEE ON NUTRITION.

    更新日期:2017-06-01 00:00:00

  • Gabapentin successfully manages chronic unexplained irritability in children with severe neurologic impairment.

    abstract::Neurologically impaired children have an increased frequency of recurrent pain and irritability that persist in some despite comprehensive evaluation and management of possible pain sources. We hypothesized that visceral hyperalgesia was a source of chronic unexplained irritability and report the outcome of gabapentin...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2006-1609

    authors: Hauer JM,Wical BS,Charnas L

    更新日期:2007-02-01 00:00:00

  • Computer-Aided Recognition of Facial Attributes for Fetal Alcohol Spectrum Disorders.

    abstract:OBJECTIVES:To compare the detection of facial attributes by computer-based facial recognition software of 2-D images against standard, manual examination in fetal alcohol spectrum disorders (FASD). METHODS:Participants were gathered from the Fetal Alcohol Syndrome Epidemiology Research database. Standard frontal and o...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2016-2028

    authors: Valentine M,Bihm DCJ,Wolf L,Hoyme HE,May PA,Buckley D,Kalberg W,Abdul-Rahman OA

    更新日期:2017-12-01 00:00:00

  • Prospective evaluation of postnatal steroid administration: a 1-year experience from the California Perinatal Quality Care Collaborative.

    abstract:OBJECTIVE:Postnatal steroids (PNSs) are used frequently to prevent or treat chronic lung disease (CLD) in the very low birth weight (VLBW) infant, and their use continues despite concerns regarding an increased incidence of longer-term neurodevelopmental abnormalities in such infants. More recently, there has been a su...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2005-0796

    authors: Finer NN,Powers RJ,Ou CH,Durand D,Wirtschafter D,Gould JB,California Perinatal Quality Care Collaborative Executive Committee.

    更新日期:2006-03-01 00:00:00

  • Targeting Sleep, Food, and Activity in Infants for Obesity Prevention: An RCT.

    abstract:OBJECTIVE:The few existing early-life obesity prevention initiatives have concentrated on nutrition and physical activity, with little examination of sleep. METHODS:This community-based, randomized controlled trial allocated 802 pregnant women (≥16 years, <34 weeks' gestation) to: control, FAB (food, activity, and bre...

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2016-2037

    authors: Taylor BJ,Gray AR,Galland BC,Heath AM,Lawrence J,Sayers RM,Cameron S,Hanna M,Dale K,Coppell KJ,Taylor RW

    更新日期:2017-03-01 00:00:00

  • Use of trained mothers to teach interviewing skills to first-year medical students: a follow-up study.

    abstract::This report describes an attempt to evaluate the effectiveness of "trained mother" interviews early in the medical school curriculum. As an adjunct to a first-year course that teaches interviewing techniques, half of the students were exposed to an interview with one of three trained mothers early in the course. This ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Stillman PL,Sabers DL,Redfield DL

    更新日期:1977-08-01 00:00:00

  • Report of the National Institute of Neurological Disorders and Stroke workshop on perinatal and childhood stroke.

    abstract::The National Institute of Neurological Disorders and Stroke and the Office of Rare Disorders sponsored a workshop on perinatal and childhood stroke in Bethesda, Maryland, on September 18 and 19, 2000. This was an international workshop to bring together experts in the field of perinatal and childhood stroke. Topics co...

    journal_title:Pediatrics

    pub_type:

    doi:10.1542/peds.109.1.116

    authors: Lynch JK,Hirtz DG,DeVeber G,Nelson KB

    更新日期:2002-01-01 00:00:00

  • Phototherapy for neonatal hyperbilirubinemia in "healthy" and "ill" infants.

    abstract::The effectiveness of phototherapy for nonhemolytic hyperbilirubinemia was evaluated in two groups of closely matched newborns, one group consisting of "healthy" and the other "ill" infants. Phototherapy was equally effective in reducing bilirubin levels in both groups of infants. It would seem to be the treatment of c...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Tan KL

    更新日期:1976-06-01 00:00:00

  • Routine admission urinalysis examination in pediatric patients: a poor value.

    abstract::The urinalysis has long been considered an important screening test for hospitalized children. The value of the admission urinalyses, required by hospital bylaws, was assessed for detecting urinary tract disease in children admitted to a day-care unit or impatient medical or surgical services during the months of June...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Mitchell N,Stapleton FB

    更新日期:1990-09-01 00:00:00

  • Pacifying effects of nonnutritive sucking on term and preterm neonates during heelstick procedures.

    abstract::Behavioral state, heart rate, and respiration were monitored during heelstick procedures in samples of healthy, term neonates (N = 48) and preterm neonates treated in minimal care (N = 48) and intensive care (N = 48) nurseries. The treated infants who were given pacifiers spent significantly less time fussing and cryi...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Field T,Goldson E

    更新日期:1984-12-01 00:00:00

  • Postconcussive symptom exaggeration after pediatric mild traumatic brain injury.

    abstract:BACKGROUND:A minority of pediatric patients who have mild traumatic brain injury (mTBI) report persistent postconcussive symptoms. In adults, failure on validity tests, which help to detect exaggerated or feigned problems, is associated with symptom complaints. No pediatric studies have examined the relationship betwee...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2013-3195

    authors: Kirkwood MW,Peterson RL,Connery AK,Baker DA,Grubenhoff JA

    更新日期:2014-04-01 00:00:00

  • A successful city-wide smoke detector giveaway program.

    abstract::Each year, 5,000 Americans die and 300,000 are hospitalized as a result of 2.8 million residential fires. Almost all house fires allow time for safe exit if an early warning is given. Smoke detectors are an effective, reliable, and inexpensive method of providing such warning. After an upsurge of deaths related to fir...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Gorman RL,Charney E,Holtzman NA,Roberts KB

    更新日期:1985-01-01 00:00:00

  • Hypothermia and hyperthermia in children after resuscitation from cardiac arrest.

    abstract:OBJECTIVE:In experimental models of ischemic-anoxic brain injury, changes in body temperature after the insult have a profound influence on neurologic outcome. Specifically, hypothermia ameliorates whereas hyperthermia exacerbates neurologic injury. Accordingly, we sought to determine the temperature changes occurring ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.106.1.118

    authors: Hickey RW,Kochanek PM,Ferimer H,Graham SH,Safar P

    更新日期:2000-07-01 00:00:00

  • Please Test My Child for a Cancer Gene, but Don't Tell Her.

    abstract::A 38-year-old woman is diagnosed with Li-Fraumeni syndrome, an autosomal dominant genetic condition that predisposes to a variety of cancers. The woman has an 11-year-old daughter. The geneticist recommends that the child be tested for the Li-Fraumeni genetic variant. The mother is concerned about the impact of testin...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2017-2238

    authors: Bester J,Sabatello M,van Karnebeek CDM,Lantos JD

    更新日期:2018-04-01 00:00:00

  • Change in prevalence of congenital defects in children with Prader-Willi syndrome.

    abstract:OBJECTIVE:The aim of this study was to assess the prevalence of congenital defects observed in patients with Prader-Willi syndrome (PWS) and to compare this prevalence with that described in the general population. In addition, these findings were correlated with the different etiologic subtypes. METHODS:A total of 18...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2012-1103

    authors: Torrado M,Foncuberta ME,Perez MF,Gravina LP,Araoz HV,Baialardo E,Chertkoff LP

    更新日期:2013-02-01 00:00:00

  • Vaccination and Risk of Childhood IgA Vasculitis.

    abstract:BACKGROUND AND OBJECTIVES:Immunoglobulin A vasculitis (IgAV) might develop after vaccination. However, this potential relationship is essentially based on case reports, and robust pharmaco-epidemiologic data are scarce. We aimed to investigate the effect of vaccination on short-term risk of IgAV in children. METHODS:W...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2018-0841

    authors: Piram M,Gonzalez Chiappe S,Madhi F,Ulinski T,Mahr A

    更新日期:2018-11-01 00:00:00

  • The relationship between maternal hypertensive disease of pregnancy and the incidence of idiopathic respiratory distress syndrome.

    abstract::The relationship between maternal hypertensive disease of pregnancy (HDOP) and idiopathic respiratory distress syndrome (IRDS) was analyzed in 2,105 premature infants weighing between 1,000 and 2,199 gm and born between January 1968 and December 1975 at the Kings County Hospital Center and State University Hospital. H...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Yoon JJ,Kohl S,Harper RG

    更新日期:1980-04-01 00:00:00

  • Human granulocyte colony-stimulating factor may improve outcome attributable to neonatal sepsis complicated by neutropenia.

    abstract:OBJECTIVES:To determine whether adjunctive therapy with recombinant human granulocyte colony-stimulating factor (rhG-CSF) could reverse sepsis-associated neonatal neutropenia and improve neonatal survival compared with conventional therapy in a phase I/II-type trial. STUDY DESIGN:An intravenous infusion of rhG-CSF (10...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章

    doi:10.1542/peds.100.1.e6

    authors: Kocherlakota P,La Gamma EF

    更新日期:1997-07-01 00:00:00

  • Severe fatigue in adolescents: a common phenomenon?

    abstract:OBJECTIVE:The purpose of this study was to determine the prevalence of severe fatigue in adolescent boys and girls, to explore the role of lifestyle factors in fatigue, and to investigate whether severe fatigue in a healthy population is associated with depression, anxiety, and comorbid factors also observed in chronic...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2005-2575

    authors: ter Wolbeek M,van Doornen LJ,Kavelaars A,Heijnen CJ

    更新日期:2006-06-01 00:00:00

  • Prolonged mechanical ventilation and intracranial hemorrhage: impact on developmental progress through 18 months in infants weighing 1,200 grams or less at birth.

    abstract::In this prospective, longitudinal study, the relative impact of intracranial hemorrhage and prolonged mechanical ventilation on developmental progress during the first 18 months of life of infants weighing 1,200 g or less at birth was examined. A total of 159 surviving infants were divided into two groups: infants wit...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Bozynski ME,Nelson MN,Matalon TA,O'Donnell KJ,Naughton PM,Vasan U,Meier WA,Ploughman L

    更新日期:1987-05-01 00:00:00

  • Translating child abuse research into action.

    abstract::The Child Abuse Recognition Experience Study revealed that primary care clinicians did not always follow the legal mandate to report suspected child abuse to child protective services. National child abuse experts representing different disciplines met in a 2-day conference in January 2007 to discuss and develop new s...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2008-0715c

    authors: Flaherty EG,Sege RD,Hurley TP

    更新日期:2008-09-01 00:00:00