Abstract:
:Neurologically impaired children have an increased frequency of recurrent pain and irritability that persist in some despite comprehensive evaluation and management of possible pain sources. We hypothesized that visceral hyperalgesia was a source of chronic unexplained irritability and report the outcome of gabapentin treatment in 9 severely neurologically impaired children. Caregivers reported marked improvement after treatment ranging from 3 months to 3 years. Nystagmus in 1 child was the only noted adverse effect. Visceral hyperalgesia may be a source of unexplained irritability in the neurologically impaired child. Symptoms may improve with gabapentin treatment.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Hauer JM,Wical BS,Charnas Ldoi
10.1542/peds.2006-1609subject
Has Abstractpub_date
2007-02-01 00:00:00pages
e519-22issue
2eissn
0031-4005issn
1098-4275pii
119/2/e519journal_volume
119pub_type
杂志文章相关文献
PEDIATRICS文献大全abstract:OBJECTIVE:Although it is well documented that breastfeeding promotes health and development of very low birth weight (VLBW) infants, lactation initiation among mothers of VLBW infants is low. Mothers are anxious about the health of their children, and medical staff may be reluctant to promote breastfeeding out of conce...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2005-0267
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVES:The objective of this study was to document the psychological adjustment of adolescents who were conceived through donor insemination by lesbian mothers who enrolled before these offspring were born in the largest, longest running, prospective, longitudinal study of same-sex-parented families. METHODS:Betwe...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2009-3153
更新日期:2010-07-01 00:00:00
abstract::There are more migrants, refugees, and immigrants adrift in the world today than at any time in the recent past. Doctors and hospitals must care for people from many different cultures, countries, and religious backgrounds. We sometimes find our own deeply held beliefs and values challenged. In this "Ethics Rounds," w...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2017-0690
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVES:Neonatal thrombocytopenia occurs commonly in neonatal intensive care units. The role of the thrombopoietin (Tpo) system in normal neonatal platelet regulation and neonatal thrombocytopenia is not well understood. The purpose of our study was to: 1) determine the normal Tpo level at birth in healthy nonthromb...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.105.6.1286
更新日期:2000-06-01 00:00:00
abstract::Neonatal hyperviscosity syndrome is known to affect multiple organ systems. The effects of polycythemic hyperviscosity on cutaneous blood flow and transcutaneous PO2 and PCO2 were compared in ten term infants prior to and following correction of the hyperviscous state. Cutaneous blood flow was measured by the heat cle...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1984-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Rates of adult women receiving contraceptive provision when simultaneously prescribed a known teratogen are alarmingly low. The prevalence of this behavior among pediatric providers and their adolescent patients is unknown. The objective of this study was to describe pediatric provider behavio...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2015-1454
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:Hospitalization of clinically stable ventilator-dependent children in an intensive care unit (ICU) remains the standard in most pediatric centers. The aim of this study was to determine whether chronically ventilator-dependent children could be hospitalized safely in a non-ICU setting. METHODS:All ventilator...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.101.2.257
更新日期:1998-02-01 00:00:00
abstract:OBJECTIVES:The goals were to describe the epidemiological features of pediatric nonautomobile motorized vehicle-related injuries sustained between 1990 and 2003 and to compare all-terrain vehicle-related injuries with other types of nonautomobile motorized vehicle-related injuries. METHODS:An analysis of nationally re...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2006-3612
更新日期:2007-07-01 00:00:00
abstract:OBJECTIVE:2-methylbutyryl-CoA dehydrogenase deficiency, also known as short/branched-chain acyl-CoA dehydrogenase (SBCAD) deficiency, is a recently described autosomal recessive disorder of L-isoleucine metabolism. Only 4 affected individuals in 2 families have been described. One patient developed athetoid cerebral pa...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.112.1.74
更新日期:2003-07-01 00:00:00
abstract:CONTEXT:Language barriers affect health care interactions. Large, randomized studies of the relative efficacy of interpreter modalities have not been conducted. OBJECTIVE:To compare the efficacy of telephonic and in-person medical interpretation to visits with verified bilingual physicians. METHODS:This was a prospec...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2009-0769
更新日期:2010-03-01 00:00:00
abstract:PURPOSE:To analyze changes in the clinical condition at presentation and methods of establishing the diagnosis of infantile hypertrophic pyloric stenosis (IHPS). METHODS:Retrospective review of patients who underwent pyloromyotomy (PM) for suspected IHPS at two institutions from 1969 through 1994 was performed. For th...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.100.2.e9
更新日期:1997-08-01 00:00:00
abstract:OBJECTIVE:The obesity epidemic has resulted in an increasing number of children needing multidisciplinary obesity treatment. To meet this need, pediatric obesity programs have arisen, particularly in children's hospitals. In 2008, the National Association of Children's Hospitals and Related Institutions (NACHRI) conven...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2011-0480I
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVE:To determine whether upper airway resistance syndrome (UARS) can be recognized and distinguished from obstructive sleep apnea syndrome (OSAS) in prepubertal children based on clinical evaluations, and, in a subgroup of the population, to compare the efficacy of esophageal pressure (Pes) monitoring to that of ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1996-11-01 00:00:00
abstract::Physician health and wellness is a critical issue gaining national attention because of the high prevalence of physician burnout. Pediatricians and pediatric trainees experience burnout at levels equivalent to other medical specialties, highlighting a need for more effective efforts to promote health and well-being in...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2014-2278
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVES:This is an investigation into the longitudinal patterns of bed sharing, the characteristics associated with those patterns, and the relationship with breastfeeding. METHODS:The study used prospective, population-based data from the United Kingdom to investigate nocturnal bed sharing at 5 time points from bi...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2010-1277
更新日期:2010-11-01 00:00:00
abstract:OBJECTIVE:To determine the correlation between the detection of human immunodeficiency virus type 1 (HIV-1) in breast milk, the duration of breastfeeding, and vertical transmission of HIV-1 infection in Ugandan women. METHODS:A prospective study of HIV-1 infection in pregnant Ugandan women and their infants has been o...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1996-09-01 00:00:00
abstract:BACKGROUND:Extremely preterm infants are at risk for neurodevelopmental impairment (NDI). Early cranial ultrasound (CUS) is usual practice, but near-term brain MRI has been reported to better predict outcomes. We prospectively evaluated MRI white matter abnormality (WMA) and cerebellar lesions, and serial CUS adverse f...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1542/peds.2014-0898
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVES:The objectives of this study were to determine the impact of different volume-targeted levels on the work of breathing and to investigate whether a level that reduced the work of breathing below that experienced during ventilatory support without volume targeting could be determined. METHODS:The transdiaphr...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2008-2635
更新日期:2009-04-01 00:00:00
abstract:OBJECTIVE:To review systematically and to summarize the existing literature regarding performance of rapid diagnostic tests for urinary tract infection (UTI) in children. DESIGN:Systematic review and meta-analysis. METHODS:Published articles reporting the performance of urine dipstick tests (leukocyte esterase [LE] a...
journal_title:Pediatrics
pub_type: 杂志文章,meta分析
doi:10.1542/peds.104.5.e54
更新日期:1999-11-01 00:00:00
abstract:OBJECTIVE:Although several studies have suggested that early menarche is associated with the development of adult overweight, few have accounted for childhood overweight before menarche. STUDY DESIGN:A 30-year follow-up of the original participants in the Newton Girls Study, a prospective study of development in a coh...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2004-1604
更新日期:2005-09-01 00:00:00
abstract::One of the most divisive issues in pediatrics today concerns the proper response by pediatricians to parents who refuse routine childhood immunizations for their children. Many pediatricians refuse to care for such families. Others continue to provide care and continue to try to convince parents that the benefits of i...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2016-1597
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:Students often miss school because of gastrointestinal and respiratory illnesses. We assessed the effectiveness of a multifactorial intervention, including alcohol-based hand-sanitizer and surface disinfection, in reducing absenteeism caused by gastrointestinal and respiratory illnesses in elementary school ...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2007-2597
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The effects of in utero methamphetamine exposure on behavioral problems in school-aged children are unclear. Our objective for this study was to evaluate behavior problems in children at aged 3, 5, and 7.5 years who were prenatally exposed to methamphetamine. METHODS:Subjects were enrolled in...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1542/peds.2019-0270
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVE:To determine how sociodemographic factors and type of insurance influence use of medical and health-related services by children with special health care needs (CSHCN), after controlling for need. METHODS:A cross-sectional analysis of 1994 National Health Interview Disability Survey was conducted. Children b...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1542/peds.112.3.593
更新日期:2003-09-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to identify important clinical predictors of change in the functional status of children with perinatally acquired human immunodeficiency virus (HIV) infection. METHODS:Children who were perinatally exposed to HIV underwent evaluation of growth, nutritional, and functional statu...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.106.2.e24
更新日期:2000-08-01 00:00:00
abstract::Initial reports of congenital Zika virus (ZIKV) infection focused on microcephaly at birth with severe brain anomalies; the phenotype has broadened to include microcephaly that develops after birth and neurodevelopmental sequelae. In this narrative review, we summarize medical literature describing motor abnormalities...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2017-2038F
更新日期:2018-02-01 00:00:00
abstract::Cocaine use during pregnancy was assessed by interviews and urine assays obtained prenatally and immediately postpartum from 679 urban women enrolled in prenatal care. Of these, 17% were found to have used cocaine at least once during pregnancy. Eight percent had urine assays positive for cocaine metabolites using the...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1988-12-01 00:00:00
abstract:OBJECTIVE:Tuberculosis (TB) control programs have been less successful among children than among adults in the United States. Between 1992 and 1997, the rate of decline of TB cases among 0- to 14-year-old children was less than the rate of decline among any other age group of US-born persons. Because of the higher prev...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.106.1.e1
更新日期:2000-07-01 00:00:00
abstract::In adults with chronic kidney disease (CKD), reduced levels of vasculoprotective endothelial progenitor cells (EPCs) may contribute to their increased risk of cardiovascular disease. Children with CKD also show signs of cardiovascular disease. However, to our knowledge, there have been no studies on circulating EPC le...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2009-3346
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVES:Coronaviruses cause upper respiratory illness and occasionally lower tract disease in susceptible populations. In this study we examined the prevalence of 4 human coronaviruses, including subtypes OC43, 229E, and the recently described NL63 and HKU1 in a pediatric population presenting to a children's hospit...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2006-1406
更新日期:2007-01-01 00:00:00