Abstract:
:Pneumocystis carinii pneumonia is a frequent manifestation of the acquired immune deficiency syndrome (AIDS). It usually presents radiologically as diffuse bilateral infiltrates and histologically as a foamy, eosinophilic intra-alveolar exudate containing the organisms' cysts. We recently studied two rare cases of P carinii pneumonia presenting as pulmonary nodules on chest x-ray films in two patients with AIDS. The corresponding histologies were a combination of the usual intra-alveolar pattern, with an alveolar and interstitial granulomatous appearance. Pneumocystis carinii was present in both areas and was the only organism found in the tissues examined. A third case presented with the more common radiographic appearance but also had a granulomatous histology. We conclude that P carinii pneumonia should be considered in the differential diagnosis of pulmonary nodules in immunocompromised patients and that pathologists should be aware of the possibility of a granulomatous reaction to this organism.
journal_name
Chestjournal_title
Chestauthors
Bleiweiss IJ,Jagirdar JS,Klein MJ,Siegel JL,Krellenstein DJ,Gribetz AR,Strauchen JAdoi
10.1378/chest.94.3.580subject
Has Abstractpub_date
1988-09-01 00:00:00pages
580-3issue
3eissn
0012-3692issn
1931-3543pii
S0012-3692(16)30167-2journal_volume
94pub_type
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