Abstract:
BACKGROUND:Research on the effects of cigarette smoking on sleep architecture is limited. The objective of this investigation was to examine differences in sleep EEG between smokers and nonsmokers. METHODS:Smokers and nonsmokers who were free of all medical comorbidities were matched on different factors, including age, gender, race, body mass index, and anthropometric measures. Home polysomnography was conducted using a standard recording montage. Sleep architecture was assessed using visual sleep-stage scoring. The discrete fast Fourier transform was used to calculate the EEG power spectrum for the entire night within contiguous 30-s epochs of sleep for the following frequency bandwidths: delta (0.8 to 4.0 Hz); theta (4.1 to 8.0 Hz); alpha (8.1 to 13.0 Hz); and beta (13.1 to 20.0 Hz). RESULTS:Conventional sleep stages were similar between the two groups. However, spectral analysis of the sleep EEG showed that, compared to nonsmokers, smokers had a lower percentage of EEG power in the delta-bandwidth (59.7% vs 62.6%, respectively; p < 0.04) and higher percentage of EEG power in alpha-bandwidth (15.6% vs 12.5%, respectively; p < 0.001). Differences in the EEG power spectrum between smokers and nonsmokers were greatest in the early part of the sleep period and decreased toward the end. Subjective complaints of lack of restful sleep were also more prevalent in smokers than in nonsmokers (22.5% vs 5.0%, respectively; p < 0.02) and were explained, in part, by the differences in EEG spectral power. CONCLUSIONS:Cigarette smokers manifest disturbances in the sleep EEG that are not evident in conventional measures of sleep architecture. Nicotine in cigarette smoke and withdrawal from it during sleep may contribute to these changes and the subjective experience of nonrestorative sleep.
journal_name
Chestjournal_title
Chestauthors
Zhang L,Samet J,Caffo B,Bankman I,Punjabi NMdoi
10.1378/chest.07-1190subject
Has Abstractpub_date
2008-02-01 00:00:00pages
427-32issue
2eissn
0012-3692issn
1931-3543pii
S0012-3692(15)49091-9journal_volume
133pub_type
杂志文章相关文献
CHEST文献大全abstract:BACKGROUND:National spirometric surveillance data in the United States were last collected during 1988-1994. The objective of this study was to provide current estimates for obstructive and restrictive impairment of lung function and to examine changes since 1988-1994. METHODS:We used data from 14,360 participants age...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.12-1135
更新日期:2013-05-01 00:00:00
abstract:STUDY OBJECTIVES:To clarify the significance of a functional lung pattern characterized by a decreased vital capacity (VC) and an increased residual volume (RV), but with a normal FEV1/VC ratio. SETTING:A university teaching hospital. SUBJECTS:Patients with bronchial asthma, pulmonary emphysema, and small airways dis...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.116.1.231
更新日期:1999-07-01 00:00:00
abstract::We studied the correspondence between fluctuations of esophageal pressure measured before and after placement of a nasogastric (NG) tube in six normal volunteers. Flow, airway pressure, and esophageal pressure data from at least 20 breaths were recorded in seven ventilatory conditions in two body postures: 0 degree (s...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.106.1.137
更新日期:1994-07-01 00:00:00
abstract:INTRODUCTION:Pulmonary arterial hypertension (PAH) is the most common cause of scleroderma-related deaths. New medications for PAH patients make it necessary to identify patients with high risk factors for PAH. This study looks at the use of an exercise echocardiogram in identifying patients who may have PAH and may be...
journal_title:Chest
pub_type: 临床试验,杂志文章
doi:10.1378/chest.07-2324
更新日期:2008-07-01 00:00:00
abstract::Three patients had hypertrophic obstructive cardiomyopathy and coronary artery spasm. The clinical diagnosis of hypertrophic obstructive cardiomyopathy, in all patients, was confirmed by echocardiography and angiography. Significant spasm of the right coronary artery was demonstrated in each patient by selective coron...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.76.6.636
更新日期:1979-12-01 00:00:00
abstract:INTRODUCTION:Managed care, both via staff model health maintenance plans and nonstaff model plans, has become a major source of health-care funding in the United States. However, very little is known about the asthma-specific products and services offered by these plans. The purpose of this study is to examine the asth...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.116.suppl_2.173s
更新日期:1999-10-01 00:00:00
abstract::Strapping of the chest causes decreased lung volumes and increased elastic recoil pressure. Such strapping was used in conjunction with single-breath nitrogen washout to study the effects of changes in these factors on the dynamics of the small airways. Studies consisted of simultaneous measurements of the quasistatic...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.76.1.83
更新日期:1979-07-01 00:00:00
abstract:BACKGROUND:The use of noninvasive ventilation (NIV) in acute exacerbation of COPD has increased over time. However, little is known about patient factors influencing its use in routine clinical practice. METHODS:This was a retrospective cohort study of 723,560 hospitalizations for exacerbation of COPD at 475 hospitals...
journal_title:Chest
pub_type: 杂志文章,多中心研究
doi:10.1378/chest.14-1216
更新日期:2015-04-01 00:00:00
abstract:STUDY OBJECTIVE:To determine the clinical and radiographic findings of nontuberculous mycobacteria (NTM) other than Mycobacterium avium complex (MAC) and Mycobacterium kansasii in AIDS compared with non-AIDS patients. DESIGN:A retrospective chart review of all patients in whom NTM other than MAC complex and M kansasii...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.114.1.138
更新日期:1998-07-01 00:00:00
abstract::Closure of ventricular septal defects through the aortic valve annulus has been described for a variety of cardiac anomalies. This technique is most appropriate when simultaneous aortic valve replacement is anticipated. A continuous suture through the patch material may produce a purse-string effect upon the aortic va...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.70.2.311
更新日期:1976-08-01 00:00:00
abstract:BACKGROUND:Skeletal muscle dysfunction occurring as a result of ICU admission associates with higher mortality. Although preadmission higher BMI correlates with better outcomes, the impact of baseline muscle and fat mass has not been defined. We therefore investigated the association of skeletal muscle and fat mass at ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1016/j.chest.2018.10.023
更新日期:2019-02-01 00:00:00
abstract::Random assessments of SaO2 were performed via pulse oximetry in 274 hospitalized non-ICU patients prescribed supplemental O2 in a large tertiary care university hospital. In 507 assessments performed in patients inspiring the prescribed O2, 426 were receiving excessive amounts of O2 to maintain a SaO2 > or = 92 percen...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.102.6.1672
更新日期:1992-12-01 00:00:00
abstract:BACKGROUND:Critically ill patients who develop ARDS have substantial associated morbidity and mortality. Circulating mitochondrial DNA (mtDNA) released during critical illness causes endothelial dysfunction and lung injury in experimental models. This study hypothesized that elevated plasma mtDNA is associated with ARD...
journal_title:Chest
pub_type: 杂志文章
doi:10.1016/j.chest.2019.09.028
更新日期:2020-01-01 00:00:00
abstract::An asymptomatic young man presented with a cardiac murmur and hypertension only in the right arm. Angiograms showed kinking of the aortic arch with a figure-eight appearance consistent with pseudocoarctation. Before the kinked segment, also demonstrated were a stenotic lesion in the aortic arch proximal to the left ca...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.97.5.1239
更新日期:1990-05-01 00:00:00
abstract:STUDY OBJECTIVE:In the present study, we evaluated the leukocyte esterase (LE) area of a reagent strip designed for urinalysis for the semiquantitative measurement of the percentage of polymorphonuclear neutrophils (PMNs) in BAL fluid. DESIGN:Prospective. The relative PMN counts (obtained by conventional microscopy an...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.118.5.1450
更新日期:2000-11-01 00:00:00
abstract::A 32-year-old man was admitted to the emergency department of our hospital after experiencing a peripheral arterial embolism. Investigation of the possible embolic sources in an otherwise asymptomatic patient revealed the existence of a left ventricular diverticulum. The left ventricular diverticulum is a rare congeni...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.127.4.1452
更新日期:2005-04-01 00:00:00
abstract::The factors that influence decision making among surgeons are not well understood. We evaluated how tumor stage in patients subjected to potentially curative surgery for lung cancer affects the self-reported follow-up strategies employed by practicing surgeons. Hypothetical patient profiles and a detailed questionnair...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.111.1.99
更新日期:1997-01-01 00:00:00
abstract::Propofol, a new intravenous sedative agent, was investigated in 41 asthmatic patients undergoing day-case (outpatient) fiberoptic bronchoscopy. The study design was a randomized comparison between propofol and midazolam, which is a well-established intravenous sedative agent. The age, weight, and American Society of A...
journal_title:Chest
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1378/chest.104.4.1029
更新日期:1993-10-01 00:00:00
abstract:BACKGROUND:Although the physiologic range of pulmonary artery systolic pressure (PASP) has been reported, data on how it is manifested in athletes are limited. The aim of the present study was to explore the full spectrum of PASP and the long-term training impact in a large population of highly trained athletes. METHO...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.10-1260
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND:The tumor microenvironment, of which cancer-associated fibroblasts (CAFs) and tumor-associated macrophages (TAMs) are the major cellular components, plays an important role in tumor progression. This study evaluated the significance of podoplanin-positive CAFs and CD204-positive TAMs, which may reflect tumor...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.11-2458
更新日期:2012-07-01 00:00:00
abstract::The contemporary surgical repertoire for the evaluation and treatment of patients with lung cancer includes the bronchoscope, mediastinoscope, thoracoscope, and standard surgical instrumentation. The recent advances in video optics and the development of endoscopic instruments have significantly expanded the surgical ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.107.6_supplement.298s
更新日期:1995-06-01 00:00:00
abstract::Long-term oxygen is the only therapy that has been shown to improve survival in patients with chronic obstructive pulmonary disease. The aim of this study was to assess the predictors of survival in such patients treated with long-term oxygen therapy. We studied 179 patients who were assessed for long-term oxygen ther...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.100.6.1522
更新日期:1991-12-01 00:00:00
abstract::We wanted to determine the efficacy of dobutamine infusions and Prbc transfusions on splanchnic tissue oxygen utilization by measuring gastric pHi. Physiologic parameters and pHi measurements via the use of a gastric tonometer were obtained in 21 septic patients before and after the administration of a dobutamine infu...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.102.1.184
更新日期:1992-07-01 00:00:00
abstract::The spontaneous variability of arterial blood gas and pH values (ABGs) was examined in a group of 28 typical stable medical ICU patients under a variety of ventilatory conditions. In each patient, 13 ABG specimens were measured at 5-min intervals during a 1-h study period using a new bedside, extravascular fluorescent...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.106.1.187
更新日期:1994-07-01 00:00:00
abstract:STUDY OBJECTIVES:To assess the functional sequelae (FS) of patients with tuberculous pleurisy (TP), to analyze the influence of different factors in the occurrence of these FS, and, finally, to evaluate the relationship between the FS and roentgenographic sequelae. DESIGN:An observational, retrospective study. SETTIN...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.123.6.1996
更新日期:2003-06-01 00:00:00
abstract:CASE PRESENTATION:A 62-year-old woman with a history of partially treated Graves disease and hypertension presented with approximately 3 weeks of worsening fatigue, lower extremity myalgias, and shortness of breath. Her medical history included a thyroid radiofrequency ablation several years earlier. Following the abla...
journal_title:Chest
pub_type:
doi:10.1016/j.chest.2019.09.041
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:Platelet activation reduces pulmonary microvascular blood flow and contributes to inflammation; these factors have been implicated in the pathogenesis of COPD and emphysema. We hypothesized that regular use of aspirin, a platelet inhibitor, would be associated with a slower progression of emphysema-like lung...
journal_title:Chest
pub_type: 杂志文章,多中心研究
doi:10.1016/j.chest.2017.11.031
更新日期:2018-07-01 00:00:00
abstract::The issue of tobacco industry responsibility for population health problems and compensation for their treatment has been growing since the 1960s. In 1999, the state attorneys general collectively launched the largest class action lawsuit in US history and sued the tobacco industry to recover the costs of caring for s...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.09-0982
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:Among patients hospitalized for community-acquired pneumonia (CAP), the risk factors for short-term hospital readmission after discharge are unknown. METHODS:We conducted a prospective observational study of 1,117 patients who had been discharged alive after hospitalization for CAP. We collected variables a...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.08-2950
更新日期:2009-10-01 00:00:00
abstract::Despite major advances in our understanding of the pathophysiologic processes leading to pulmonary arterial hypertension and recent developments in therapeutic approaches, the long-term prognosis for patients with pulmonary arterial hypertension remains unsatisfactory. Early detection and adequate clinical classificat...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.128.6_suppl.622S-a
更新日期:2005-12-01 00:00:00