Abstract:
:Cardiac cell therapy has emerged as a controversial yet promising therapeutic strategy. Both experimental data and clinical applications in this field have shown modest but tangible benefits on cardiac structure and function and underscore that transplanted stem-progenitor cells can attenuate the postinfarct microenvironment. The paracrine factors secreted by these cells represent a pivotal mechanism underlying the benefits of cell-mediated cardiac repair. This article reviews key studies behind the paracrine effect related to the cardiac reparative effects of cardiac cell therapy.
journal_name
J Cardiovasc Transl Resjournal_title
Journal of cardiovascular translational researchauthors
Maltais S,Tremblay JP,Perrault LP,Ly HQdoi
10.1007/s12265-010-9198-2subject
Has Abstractpub_date
2010-12-01 00:00:00pages
652-62issue
6eissn
1937-5387issn
1937-5395journal_volume
3pub_type
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