Induction of monocyte chemoattractant protein-1 by nicotine in pancreatic ductal adenocarcinoma cells: role of osteopontin.

abstract：BACKGROUND:Although portal venous tumor thrombus (PVTT) is regarded as an ominous prognostic factor in patients with hepatocellular carcinoma (HCC), the optimal treatment method for maximizing both safety and long-term outcome has not yet been discussed. We describe a surgical technique in which the venous wall is peel...

journal_title：Surgery

authors： Inoue Y,Hasegawa K,Ishizawa T,Aoki T,Sano K,Beck Y,Imamura H,Sugawara Y,Kokudo N,Makuuchi M

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Individual trials of small-volume resuscitation of 7.5% NaCl (HS) with and without 6% dextran 70 (HSD) for the treatment of trauma have failed to provide convincing evidence of efficacy. We performed a meta-analysis to evaluate the effects of HS and HSD on survival until discharge or for 30 days. We identifi...

journal_title：Surgery

authors： Wade CE,Kramer GC,Grady JJ,Fabian TC,Younes RN

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:An overproduction of corticosterone during severe sepsis results in increased apoptosis of immune cells, which may result in relative immunosuppression and an impaired ability to fight infections. We have previously demonstrated that administration of tubastatin A, a selective inhibitor of histone deacetylas...

journal_title：Surgery

authors： Zhao T,Li Y,Bronson RT,Liu B,Velmahos GC,Alam HB

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Differentiation between parathyroid hyperplasia and adenoma is difficult and based on the surgeon's skill. Microarrays and other sophisticated research tools generate information about differential gene expression in various tissues. Exploration of genes that express differentially in 1 tissue will enable id...

journal_title：Surgery

authors： Schachter PP,Ayesh S,Schneider T,Laster M,Czerniak A,Hochberg A

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:This study was conducted to evaluate the effects of tumor removal and body weight loss on insulin resistance. METHODS:Insulin sensitivity was examined in 12 patients with cancer and stable weight and five patients with cancer and weight loss before operation, six patients after complete tumor removal, and t...

journal_title：Surgery

authors： Yoshikawa T,Noguchi Y,Matsumoto A

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:Outcomes after operative management of benign hepatic lesions are ill-defined. We sought to define patient-reported quality of life (QOL) postoperatively for benign hepatic tumors. METHODS:Patients who underwent surgery for benign liver lesions (n = 255) were invited to complete a QOL survey designed using ...

journal_title：Surgery

authors： Kneuertz PJ,Marsh JW,de Jong MC,Covert K,Hyder O,Hirose K,Schulick RD,Choti MA,Geller DA,Pawlik TM

更新日期：2012-08-01 00:00:00

abstract：:Active-specific immunotherapy with concanavalin A or with neuraminidase-modified syngeneic tumor cells has been studied in an experimental model of colon cancer. Systemic immunotherapy with concanavalin A-modified tumor cells or with neuraminidase-modified tumor cells has resulted in up to 70 percent cure of rats rece...

journal_title：Surgery

authors： Enker WE,Jacobitz JL

更新日期：1976-08-01 00:00:00

abstract：:This is a report of a patient with a thrombosed Warren shunt and recurrent variceal hemorrhage who demonstrated compartmentalized venous hypertension in the mesenteric and gastrosplenic systems. Although the mesenteric presssure was normalized by the construction of a mesocaval interposition shunt, the gastrosplenic v...

journal_title：Surgery

authors： Law DK,Moore EE

更新日期：1979-05-01 00:00:00

abstract：:The object of this article is to assess the value of human serum albumin (HSA) in the initial resuscitation of hypotensive trauma victims. Thirty-six patients (mean age = 30 years) in shock from trauma who underwent laparotomies were randomly assigned to either Ringer's lactate solution (RL) resuscitation or 4% HSA in...

journal_title：Surgery

authors： Moss GS,Lowe RJ,Jilek J,Levine HD

更新日期：1981-04-01 00:00:00

abstract：:Peripheral parenteral nutrition avoids the use of central lines and is a useful means of nutritional support for selected patients. Amino acids alone have been used for peripheral parenteral nutrition and have been shown to give near nitrogen equilibrium. The addition of small amounts of dextrose to amino acids furthe...

journal_title：Surgery

authors： Fairfull-Smith RJ,Stoski D,Freeman JB

更新日期：1982-10-01 00:00:00

abstract：BACKGROUND:We determined the effect of infusing the iron chelator deferoxamine complexed to hetastarch on the degree of lung dysfunction and systemic abnormalities produced by a severe smoke exposure. METHODS:Adult sheep were given a smoke exposure under anesthesia that produced a peak carboxyhemoglobin between 40% an...

journal_title：Surgery

authors： Demling R,LaLonde C,Ikegami K

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:Difficult cephalad exposure during carotid endarterectomy in patients with high plaque (HP) may lead to increased incidence of complications after carotid endarterectomy. We report on our experience of carotid endarterectomy in patients with HP. METHODS:This is a retrospective review of 1,233 consecutive pa...

journal_title：Surgery

authors： Vang S,Hans SS

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Squamous cell carcinoma of the head and neck (SCCHN) is the sixth most common cancer worldwide. Greater than 90% of SCCHN of the oropharynx overexpress the epidermal growth factor receptor (EGFR or HER1). Cetuximab (Erbitux-TM) is a humanized anti-HER1 monoclonal antibody (mAb) that binds to HER1 overexpress...

journal_title：Surgery

authors： Luedke E,Jaime-Ramirez AC,Bhave N,Roda J,Choudhary MM,Kumar B,Teknos TN,Carson WE 3rd

更新日期：2012-09-01 00:00:00

abstract：:Axial computerized tomography is a useful tool in the evaluation of either primary or metastatic hepatic neoplasms. An adjunct to this technique is visceral arterial enhanced computerized tomography (AECT). To determine the effectiveness of this modality, bolus intravenous enhanced computerized tomography scans and AE...

journal_title：Surgery

authors： Goulet RJ Jr,Seekri I,Inman M,Kopecky KK,Madura JA,Grosfeld JL

更新日期：1990-10-01 00:00:00

abstract：BACKGROUND:The effects of intestinal inflammation on the central nervous system are unknown. The dorsal motor nucleus of the vagus (DMNV) integrates peripheral and central signals and sends efferent signals to the gastrointestinal system. The purpose of this study was to determine the effects of intestinal inflammation...

journal_title：Surgery

authors： Ammori JB,Zhang WZ,Li JY,Chai BX,Mulholland MW

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Propranolol has been shown previously to restore bone marrow function and improve anemia after lung contusion/hemorrhagic shock. We hypothesized that daily clonidine administration would inhibit central sympathetic outflow and restore bone marrow function in our rodent model of lung contusion/hemorrhagic sho...

journal_title：Surgery

authors： Alamo IG,Kannan KB,Ramos H,Loftus TJ,Efron PA,Mohr AM

更新日期：2017-03-01 00:00:00

abstract：:To clarify the physiopathologic mechanism leading to a marked increase in aromatic amino acids (AAA) in acute hepatic failure (AHF), we compared two experimental models of AHF. Ten pigs were submitted to one-stage hepatic devascularization (group A); in eight other pigs total hepatectomy was performed (group B). The a...

journal_title：Surgery

authors： Mazziotti A,Bernardi M,Antonini L,Dioguardi FS,Bellusci R,Papa V,Tacconi C,Gasbarrini G,Cavallari A,Possati L

更新日期：1981-09-01 00:00:00

abstract：:We will describe the development of new resectional techniques with the use of the ultrasonic scalpel in 33 patients with liver disease. Our experience is presented in the performance of anatomic and nonanatomic liver resections by use of this device. Its saline-cooled tip vibrated at ultrasonic frequencies and select...

journal_title：Surgery

authors： Hodgson WJ,DelGuercio LR

更新日期：1984-02-01 00:00:00

abstract：:During the recent 5 2/3 years, hepatic resection was performed on 118 patients with hepatocellular carcinoma. Ages ranged from 17 to 78 years with an average of 57 years. There were 101 males and 17 females. Underlying cirrhosis of the liver was found in 101 cases, and chronic hepatitis was found in 16 cases. Before s...

journal_title：Surgery

authors： Nagasue N,Yukaya H,Ogawa Y,Sasaki Y,Chang YC,Niimi K

更新日期：1986-06-01 00:00:00

abstract：BACKGROUND:Routine central lymph node dissection (CLND) for papillary thyroid cancer (PTC) at the time of initial thyroidectomy has been advocated with a demonstrated decrease in post-ablation serum thyroglobulin compared to total thyroidectomy alone. Patients now present with central compartment metastatic disease aft...

journal_title：Surgery

authors： Alvarado R,Sywak MS,Delbridge L,Sidhu SB

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Nodal status is one of the most important prognostic factors for carcinoma of the papilla of Vater. The pattern of lymphatic spread and mode of recurrence were analyzed by determining the frequency of nodal involvement and antemortem and postmortem examination of patients with recurrent disease. METHODS:Fro...

journal_title：Surgery

authors： Kayahara M,Nagakawa T,Ohta T,Kitagawa H,Miyazaki I

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND:The clinical importance of point mutations of ras oncogene in differentiated thyroid cancers has not been fully clarified. The purpose of this study is to determine the prognostic importance of ras mutation in papillary thyroid carcinoma. METHODS:Tumors of 91 patients with papillary carcinoma were studied; ...

journal_title：Surgery

authors： Hara H,Fulton N,Yashiro T,Ito K,DeGroot LJ,Kaplan EL

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Lysophosphatidylcholine (LysoPC) is a product of phosphatidylcholine hydrolysis by phospholipase A2, which is associated with atherosclerosis. However, the underlying molecular mechanisms are still unclear. The purpose of this study was to determine the effects of LysoPC on monolayer permeability of human co...

journal_title：Surgery

authors： Yan S,Chai H,Wang H,Yang H,Nan B,Yao Q,Chen C

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Interleukin 12 (IL-12) p70 is a heterodimeric protein (p35, p40 subunits) that promotes T-helper TH1-type cytokine response. In critically ill patients, after severe trauma or sepsis, IL-12 production is markedly impaired. We tested the hypothesis that deficiency of the transcription factor c-fos will increa...

journal_title：Surgery

authors： Roy S,Charboneau R,Cain K,DeTurris S,Melnyk D,Barke RA

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:Case-control studies have reported an inverse relationship between appendectomy and the risk of ulcerative colitis, but the association has not been confirmed in prospective studies. METHODS:Using national hospital discharge registry data in Denmark, the authors followed up 154,434 patients who underwent ap...

journal_title：Surgery

authors： Frisch M,Johansen C,Mellemkjaer L,Engels EA,Gridley G,Biggar RJ,Olsen JH

更新日期：2001-07-01 00:00:00

abstract：:The term big data has been popularized over the past decade and is often used to refer to data sets that are too large or complex to be analyzed by traditional means. Although the term has been utilized for some time in business and engineering, the concept of big data is relatively new to medicine. The reception from...

journal_title：Surgery

authors： Cobb AN,Benjamin AJ,Huang ES,Kuo PC

更新日期：2018-10-01 00:00:00

abstract：:An unusual case of Mondor's disease associated with carcinoma of the breast is reported. "Forked string" and "triple beads" have been reported previously in this disease. In this patient, however, one of the "beads" of her triple beads was malignant. It is suggested that biopsy and histologic examination are the best ...

journal_title：Surgery

authors： Chiedozi LC,Aghahowa JA

更新日期：1988-04-01 00:00:00

abstract：BACKGROUND:Previous studies using simulation-based curricula have focused largely on technical skills. We developed a set of simulation-based modules that focus on intraoperative decision making. The objective of this study was to conduct a faculty evaluation of: (1) the usefulness of 4 newly developed, simulation-base...

journal_title：Surgery

authors： Pugh CM,DaRosa DA,Santacaterina S,Clark RE

更新日期：2011-04-01 00:00:00

abstract：:Eleven parathyroid cysts were found in 325 patients who underwent parathyroid operations. Ten cysts were located in the neck and one was located in the mediastinum. The cysts ranged in size from 1.6 to 10 cm with a mean of 3.9 cm. The patients who had cysts included six women and five men, and their ages ranged from 2...

journal_title：Surgery

authors： Calandra DB,Shah KH,Prinz RA,Sullivan H,Hofmann C,Oslapas R,Ernst K,Lawrence AM,Paloyan E

更新日期：1983-12-01 00:00:00

abstract：BACKGROUND:Most severe pain occurs within the first 72 hours after an operation, and current local anesthetics have a limited duration of action. HTX-011 is a dual-acting, local anesthetic containing bupivacaine, and low-dose meloxicam in an extended-release polymer. In a prior phase 3 inguinal herniorrhaphy study, HTX...

journal_title：Surgery

authors： Singla N,Winkle P,Bertoch T,Hu J,Beaton A,Redan J

更新日期：2020-11-01 00:00:00