Abstract:
BACKGROUND:Outcomes after operative management of benign hepatic lesions are ill-defined. We sought to define patient-reported quality of life (QOL) postoperatively for benign hepatic tumors. METHODS:Patients who underwent surgery for benign liver lesions (n = 255) were invited to complete a QOL survey designed using validated assessment tools. Clinicopathologic data were collected from 2 participating hepatobiliary centers and correlated with QOL data. RESULTS:The response rate was 70.2%. Most patients had a benign cystic (41.9%) or solid (47.5%) tumor; 19 (10.6%) patients had an indeterminate lesion. The lesion was most often solitary (71.5%) and median size was 7.5 cm. Most benign lesions were either a simple cyst (35.8%), hemangioma (19.6%), focal nodular dysplasia (19.6%), or hepatic adenoma (16.9%). Presenting symptoms included abdominal pain (70.9%), nausea/vomiting (5.0%), and early satiety (5.0%). Surgery involved less than hemihepatectomy (68.2%); a laparoscopic approach was utilized in 40.8% of patients. Perioperative morbidity was 16%. Postoperatively, the proportion of patients who reported moderate-to-extreme pain decreased from 46.9% to 15.6% and 6.8% at 6 months and 1-year, respectively (P < .001). Patient self-reported mean pain scores also decreased over time (preoperative, 1.65 vs 6 months, 0.63 vs 1 year, 0.28; P < .001). Patients with "moderate-to-extreme" pain preoperatively were more likely to report an improvement in pain scores (odds ratio, 1.96; 95% confidence interval, 1.05-3.66; P = .03). Many patients reported overall improvement in general health (40.5%) and physical health (39.3%; P < .001). CONCLUSION:Surgery for benign liver lesions is associated with high patient satisfaction and improved QOL. Patients with significant preoperative symptoms derive the most benefit from surgery.
journal_name
Surgeryjournal_title
Surgeryauthors
Kneuertz PJ,Marsh JW,de Jong MC,Covert K,Hyder O,Hirose K,Schulick RD,Choti MA,Geller DA,Pawlik TMdoi
10.1016/j.surg.2012.05.004subject
Has Abstractpub_date
2012-08-01 00:00:00pages
193-201issue
2eissn
0039-6060issn
1532-7361pii
S0039-6060(12)00212-7journal_volume
152pub_type
杂志文章,多中心研究相关文献
SURGERY文献大全abstract::The intestinal phase of gastric acid secretion is mediated by the putative hormone entero-oxyntin. The release of the hormone has been demonstrated in both dog and rat models during an intestinal meal of liver extract. The maximal gastric acid response to pentagastrin is augmented by the presence of liver extract in t...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1988-08-01 00:00:00
abstract::Until recently, vascular surgeons have had to make judgments based on an impression of their experiences rather than upon the actual facts. Presently, with the simplified and less costly use of computers, the establishment of a computerized data base is feasible. Our goal had been to develop a system suitable for micr...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1980-12-01 00:00:00
abstract:BACKGROUND:Laparoscopic techniques are being used increasingly in the repair of ventral hernias and offer the potential benefits of a shorter hospital stay, decreased wound complications, and possibly a lower recurrence rate. Despite good results from high-volume centers, significant complications may occur with this a...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2005.06.054
更新日期:2005-10-01 00:00:00
abstract::Metabolic alkalosis secondary to chloride depletion, especially following gastrointestinal surgery and associated with acute renal failure, is a frequent clinical occurrence. Management of the resultant acid-base disturbance mandates chloride replacement. The presence of oliguria limits the choice of accompanying cati...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1975-10-01 00:00:00
abstract:BACKGROUND:Pediatric umbilical hernia repair is a common procedure that requires minimal tissue disruption. We examined variation in opioid prescription fills after repair of uncomplicated umbilical hernias to characterize the types and doses of medication used and persistent postsurgical use. METHODS:Using the Truven...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2018.10.029
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:Isolated limb perfusion (ILP) with melphalan is an accepted treatment for intransit melanoma of the extremities. Using an ILP human melanoma xenograft model, we tested the hypothesis that acidosis augments the antitumor effect of melphalan and that nitric oxide (NO) induction mediates tumor regression. METH...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1067/msy.2002.125713
更新日期:2002-08-01 00:00:00
abstract::Hepatic ultrasonography (US) was performed during laparotomy in 47 patients with hepatocellular carcinomas (HCC) less than 5 cm in size. It detected more tumors than did preoperative US and other imaging modalities. In this series, 45.9% of HCCs smaller than 3 cm and 14.2% of those between 3 and 5 cm were invisible an...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract::Heterotopic rat heart allografts were performed in 35 rats. At intervals after transplantation, rats were killed and tissue concentrations of immunoassayable prostaglandin E (PGE) were measured in the native heart, transplanted heart, spleen, and thymus. A significant increase in allograft PGE activity was observed at...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1975-10-01 00:00:00
abstract:BACKGROUND:The landscape of patients with end-stage renal disease is changing with the increasing availability of kidney transplantation. In the near future, a less aggressive approach to treat secondary hyperparathyroidism might be beneficial. We report outcomes of parathyroidectomy for end-stage renal disease-related...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2020.08.014
更新日期:2021-02-01 00:00:00
abstract:BACKGROUND:Our previous work classified a taxonomy of suturing gestures during a vesicourethral anastomosis of robotic radical prostatectomy in association with tissue tears and patient outcomes. Herein, we train deep learning-based computer vision to automate the identification and classification of suturing gestures ...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2020.08.016
更新日期:2020-09-26 00:00:00
abstract::Autologous fibrin glue was evaluated as a sealant of the common bile duct (CBD) with the use of experimental animal models. It proved to be highly effective. Since it is a safe product that can be easily obtained from the patient's own blood, it may find useful application in most biliary tract procedures, liver trans...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1987-03-01 00:00:00
abstract:BACKGROUND:Barriers to trauma care for rural populations are well documented, but little is known about the magnitude of urban-rural disparities in injury mortality. This study sought to quantify differences in injury mortality comparing rural and nonrural residents with traumatic injuries. METHODS:Using data from the...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2016.06.020
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:Little is known about the value of sequential transcatheter arterial chemoembolization and portal vein embolization compared with portal vein embolization alone before major hepatectomy for large hepatocellular carcinoma. We aimed to compare early and long-term outcomes of these two strategies. METHODS:We i...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2019.09.023
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:Hepatectomy for colorectal liver metastases (CRLM) may offer good long-term survival. The impact of the tumor-free surgical margin on long-term results remains controversial, and we have assessed this component in 185 patients. METHODS:Between 1992 and 2005, 185 patients underwent primary hepatectomy with c...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2007.09.038
更新日期:2008-03-01 00:00:00
abstract:BACKGROUND:Video review for assessment of surgical performance is gaining popularity but is time consuming for busy expert reviewers, making review delays inevitable. Decreasing review time and including nonexpert reviewers may facilitate more timely reviews. We hypothesized that a shorter duration video clip would not...
journal_title:Surgery
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.surg.2017.11.011
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:There is currently little information regarding the impact of procedure volume on outcomes after open inguinal hernia repair in the United States. Our hypothesis was that increasing procedure volume is associated with lesser rates of reoperation and resource use. METHODS:The database of the Statewide Planni...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2015.03.058
更新日期:2015-09-01 00:00:00
abstract::Cerebral revascularization, using extra-anatomic bypass grafts of autologous saphenous vein, was performed in three patients to prevent or to compensate for ischemic effects of emergency ligation of a carotid artery. These ligations were required after spontaneous disruption of common carotid arteries in patients with...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1978-04-01 00:00:00
abstract:BACKGROUND:Surgery for low rectal cancer can be associated with severe bowel dysfunction and impaired quality of life. It is important to determine how patients value the trade-off between anorectal dysfunction versus abdominoperineal resection. Therefore, the objective was to determine patients' preferences for treatm...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2020.07.020
更新日期:2020-08-24 00:00:00
abstract::A model for the vascular steal phenomenon was designed and evaluated in 10 mongrel dogs in which the aortic bifurcation was used to represent a parent artery with two distal vascular beds. Right lower extremity flow was increased with a femoral arteriovenous fistula, and progressively greater stenoses were applied to ...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1984-11-01 00:00:00
abstract:BACKGROUND:The risk of invasive cancer in resected intraductal papillary mucinous neoplasm with main pancreatic duct involvement is 33%-60%. Most guidelines, therefore, advise resection of main duct intraductal papillary mucinous neoplasm and mixed type intraductal papillary mucinous neoplasm in surgically fit patients...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2018.01.025
更新日期:2018-05-16 00:00:00
abstract::The aims of this study were to determine whether ectopic pacemakers are present after meals in the Roux limbs of dogs after vagotomy and Roux gastrectomy, whether these pacemakers slow gastric emptying of liquids or solids, and whether abolishing the pacemakers with electric pacing might speed any slow emptying that o...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1989-11-01 00:00:00
abstract::Previous studies in dogs suggest that global ischemia with cardiopulmonary bypass causes increased left ventricular (LV) mass and water content. To investigate effects in humans, we developed a simplified method for mass determination by intraoperative two-dimensional echocardiography. LV mass was measured as echocard...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1984-08-01 00:00:00
abstract:BACKGROUND:Surgical residents have traditionally been evaluated by ward evaluations and multiple-choice testing; overall resident performance has seldom been objectively evaluated. We developed a comprehensive evaluation program for senior residents. The purpose of this study was to determine whether the several differ...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1994-10-01 00:00:00
abstract:BACKGROUND:Parathyroidectomy has a success rate of greater than 95% in the hands of experienced surgeons. To maintain this result in a more cost-effective way, intraoperative monitoring of intact parathyroid hormone (iPTH) has been used to decrease operative times. This technique signals when all hyperfunctioning tissu...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/s0039-6060(96)80040-7
更新日期:1996-12-01 00:00:00
abstract:BACKGROUND AND AIMS:The optimal protocol of the treatment for early gastric cancer has not been fully established. The current study was designed to elucidate the relationship between the depth of tumors with or without an ulcer and the presence of lymph node metastasis and to establish the optimal and practical therap...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1067/msy.2001.114217
更新日期:2001-06-01 00:00:00
abstract:BACKGROUND:The proportion of positive among examined lymph nodes (lymph node ratio [LNR]) has been recently proposed as an useful and easy-to-calculate prognostic factor for patients with cutaneous melanoma. However, its independence from the standard prognostic system TNM has not been formally proven in a large series...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2011.02.021
更新日期:2011-07-01 00:00:00
abstract:BACKGROUND:Only annual mammography and physical examination are recommended for the post-treatment surveillance of early stage breast cancer. METHODS:We used Texas Cancer Registry-Medicare linked data (2001-2007) to identify physician visits and use of mammography, magnetic resonance imaging (MRI), computed tomography...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2013.04.004
更新日期:2013-08-01 00:00:00
abstract:BACKGROUND:Successful parathyroidectomy for sporadic primary hyperparathyroidism (pHPT) is predicted by a 50% drop in PTH intra-operatively. Vitamin D is a known inhibitor of PTH secretion and is associated with secondary HPT following adenoma resection. This study examined the impact of 25-hydroxyvitamin D (25OHD) def...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2007.09.026
更新日期:2007-12-01 00:00:00
abstract::The efficacy of systemic interleukin-2 (IL-2) immunotherapy is dependent on a competent host immune response. This study demonstrated that protein-calorie malnutrition (PCM) inhibited the generation of an antitumor response to IL-2. A/J mice received an isocaloric diet of 2.5% or 24% casein 8 weeks before inoculation ...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1990-08-01 00:00:00
abstract:BACKGROUND:Telomerase reverse transcriptase promoter mutations were recently found to be associated with poorer prognosis in patients with papillary thyroid carcinoma. Correlation between telomerase reverse transcriptase messenger RNA expression and survival of patients with papillary thyroid carcinoma has not been det...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2020.04.054
更新日期:2021-01-01 00:00:00