Abstract:
BACKGROUND:Surgery for low rectal cancer can be associated with severe bowel dysfunction and impaired quality of life. It is important to determine how patients value the trade-off between anorectal dysfunction versus abdominoperineal resection. Therefore, the objective was to determine patients' preferences for treatment for low rectal cancer. METHODS:Ambulatory patients without colorectal cancer at a single high-volume academic colorectal referral center from September 2019 to March 2020 were included. Patients with prior stoma or malignancy were excluded. Participants were presented with a hypothetic scenario describing a low rectal cancer. A threshold task identified preferences for functional and oncologic outcomes for sphincter preservation versus abdominoperineal resection. RESULTS:A total of 123 patients were recruited. Patients preferred abdominoperineal resection over sphincter preservation if there were more than a mean of 6.7 (standard deviation 4.0) daily bowel movements, 1.9 (standard deviation 2.6) daily episodes of stool incontinence, and 6.5 (standard deviation 3.2) gas incontinence. Abdominoperineal resection was preferred over sphincter preservation in 38% if daily activities were altered owing to fecal urgency. Patients were willing to accept a 10% (interquartile range, 5-25) absolute increase in risk of margin involvement with sphincter preservation to avoid abdominoperineal resection. Abdominoperineal resection was the preferred option overall for 18% of patients. CONCLUSION:An important proportion of patients would prefer abdominoperineal resection over sphincter preservation owing to the impairments in anorectal function associated with sphincter preservation. The decision to perform sphincter preservation or abdominoperineal resection should consider how the patients' value functional outcomes with a low anastomosis.
journal_name
Surgeryjournal_title
Surgeryauthors
Lee L,Trepanier M,Renaud J,Liberman S,Charlebois P,Stein B,Fried GM,Fiore J Jr,Feldman LSdoi
10.1016/j.surg.2020.07.020subject
Has Abstractpub_date
2020-08-24 00:00:00eissn
0039-6060issn
1532-7361pii
S0039-6060(20)30464-5pub_type
杂志文章相关文献
SURGERY文献大全abstract:BACKGROUND:Adenosine released by cells during ischemia typically serves as a feedback inhibitor of further organ work. However, in ischemic intestine, adenosine appears to act via stimulatory A2b receptors to increase work in the form of chloride ion (Cl-) secretion. This unusual response may contribute to luminal flui...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/s0039-6060(96)80295-9
更新日期:1996-08-01 00:00:00
abstract:BACKGROUND:The hypermetabolic response to severe burn is characterized by muscle protein catabolism. Current opinion states that the hypermetabolic state resolves soon after complete wound closure. Clinically, we have witnessed that burned children appear to be hypermetabolic and catabolic long after full healing of th...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1067/msy.2000.108059
更新日期:2000-08-01 00:00:00
abstract:BACKGROUND:Hepatocellular carcinoma (HCC) is among the most common malignant neoplasms worldwide. Only few data on HCC in noncirrhotic livers without viral hepatitis in Western countries are available. The purpose of this study was to define the outcomes and potential prognostic factors associated with survival after h...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2012.09.015
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND:In an attempt to prevent overly aggressive treatment of low-risk thyroid cancers, the American Thyroid Association changed guideline recommendations in late 2015 to state that either hemithyroidectomy or total thyroidectomy are acceptable operations for these patients. We hypothesized that surgeons would inc...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2019.03.002
更新日期:2019-09-01 00:00:00
abstract::Previously, we documented that nonlethal doses of endotoxin cause the translocation (escape) of bacteria from the gut to systemic organs. The purpose of this study was to determine which portion(s) of the endotoxin molecule induces bacterial translocation and to examine the role of xanthine oxidase activity in the pat...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1989-08-01 00:00:00
abstract::The influence of early graft surface thromboreactivity on long-term arterial polyester (Dacron) graft patency was investigated with separate ex vivo and in vivo animal models. First, parallel, flow-regulated external aortocaval fistulae were created in five pigs with use of paired 8 mm X 35 cm crimped, warp-knitted, l...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1989-05-01 00:00:00
abstract::In this study, we have compared a bioassay procedure with high-pressure liquid chromatography (HPLC) for the determination of metronidazole levels in serum and urine. Plasma and urine of volunteers with normal or impaired renal function were obtained at various intervals after a single intravenous dose of 500 mg metro...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00
abstract::Hygroma renalis is an unusual benign tumor of the kidney. Only 24 cases have been reported previously in the world literature; 22 of these patients underwent nephrectomy. Two sisters, with the first known occurrence in siblings, are discussed and the world literature is reviewed. Our first patient underwent nephrectom...
journal_title:Surgery
pub_type: 杂志文章,评审
doi:
更新日期:1992-03-01 00:00:00
abstract::The central venous dialysis catheter has gained wide acceptance for short-term hemodialysis with the realization of the need to spare peripheral extremity vessels for the creation of more durable internal arteriovenous fistulas. The Hemocath (Quinton Instrument Co., Seattle, Wash.), a soft, silicone rubber, double-lum...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1987-11-01 00:00:00
abstract:BACKGROUND:Pancreatoduodenectomy is the standard treatment for pathologies of the pancreatic head and is performed routinely worldwide. The aim of the study was to analyze this procedure in terms of extent of surgery, technical difficulty, and clinical outcomes and thereby provide a standardized surgical categorization...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2020.11.030
更新日期:2020-12-29 00:00:00
abstract::Endorectal ileoanal anastomosis with proximal interposition of an ileal reservoir was evaluated experimentally in dogs as an approach to retain sphincteric control of defecation after proctocolectomy. Two months after the operative procedure, eight animals with a reservoir had four to eight semisolid stools per day an...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1982-03-01 00:00:00
abstract:BACKGROUND:It has been shown that vagal nerve stimulation (VNS) can affect body mass. The aim of this study was to evaluate effect of VNS on body mass, body composition, metabolic rate, and plasma leptin and IGF-I levels. METHODS:Eight female pigs were included in the study. Under general anesthesia, a bipolar electro...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2005.06.025
更新日期:2006-02-01 00:00:00
abstract:OBJECTIVE:To assess trainee satisfaction in their surgery residency with a validated instrument and identify the contributing factors. BACKGROUND:Currently, surgery is deemed unattractive by medical students and ignored by many candidates planning to enter an academic career. New insights on the rational for such lack...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2011.07.037
更新日期:2012-11-01 00:00:00
abstract:BACKGROUND:These experiments were designed to quantitatively compare the patterns of tissue thrombosis, cytokine response, and tissue viability in a murine model of partial (PI) versus complete hindlimb ischemia (CI), alone or with reperfusion (RE). METHODS:The control tension tourniquet was used to establish either P...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2005.06.005
更新日期:2005-08-01 00:00:00
abstract::Fine-needle aspirations and cutting needle biopsies were performed on 415 patients with solitary thyroid nodules. All nodules were considered hypofunctioning by scintiscans. Specimens were adequate in 399 patients. Ten percent of these patients had thyroid cancers documented by thyroidectomies. Results from either or ...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1986-12-01 00:00:00
abstract:BACKGROUND:The quick parathyroid hormone assay (QPTH) reliably measures intact parathyroid hormone (iPTH) levels intraoperatively. The accuracy in predicting postoperative calcemia is related to blood sample timing and the criteria applied. To improve specificity or to decrease the cost of QPTH, several criteria have b...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2003.06.001
更新日期:2003-12-01 00:00:00
abstract::Eleven patients wtih gallstone-related acute pancreatitis underwent urgent duodenoscopy and diathermy sphincterotomy; six had stones impacted at the papilla of Vater, and the remainder had stones in the bile duct. One patient had a gallstone in the pancreatic duct. Endoscopic removal of the duct stones resulted in a p...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1981-04-01 00:00:00
abstract::We have treated 13 patients with limb-threatening ischemia caused by acute arterial thrombosis with selective arterial infusion of streptokinase. The indications for thrombolytic therapy included medical contraindication to surgery, surgically inaccessible thrombi, arterial thrombosis following percutaneous translumin...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1983-06-01 00:00:00
abstract:BACKGROUND:No reports have yet precisely determined corticotropin (ACTH) responsiveness in virilizing adrenocortical adenoma. METHODS:Five women with an androgen-secreting adrenal adenoma were reviewed. Three of them were examined by in vitro steroidogenesis. Two of these 3 patients were studied by immunohistochemistr...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1999-04-01 00:00:00
abstract:BACKGROUND:Although portal venous tumor thrombus (PVTT) is regarded as an ominous prognostic factor in patients with hepatocellular carcinoma (HCC), the optimal treatment method for maximizing both safety and long-term outcome has not yet been discussed. We describe a surgical technique in which the venous wall is peel...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2008.09.005
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Sclerotherapy is usually effective in controlling acutely bleeding esophageal varices. It may not be as effective as shunt surgery for prevention of rebleeding; therefore we undertook a prospective study comparing interposition mesocaval shunt (MCS) and repeated sclerotherapy. METHODS:Forty-five patients (m...
journal_title:Surgery
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0039-6060(05)80248-x
更新日期:1995-05-01 00:00:00
abstract::This study compares the National Board of Medical Examiners Part II (NBME II) subtest scores of medical students attaining honors in a clinical clerkship to those of students receiving a passing score to determine if the NBME II examinations could be considered independently as valid indicators of clinical achievement...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1981-06-01 00:00:00
abstract:BACKGROUND:The observed to expected (O:E) mortality based on Injury Severity Scores (ISS) has been used to assess quality of trauma center (TC) care. Injuries in the elderly have increased, and these patients often have advanced directives, on occasion limiting aggressive care even for potentially survivable injuries; ...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2011.07.065
更新日期:2011-10-01 00:00:00
abstract::Palliative care has long been described in medical literature but only recently is being discussed in the surgical domain. Mounting evidence suggests that early integration of palliative care improves patient outcomes and this is especially true of oncology patients. Thus, the pendulum is swinging toward recognizing t...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2017.10.001
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:Prospective data on risk factors and the incidence of inguinal hernia are sparse, especially in an elderly population. The aim of this study was to determine the incidence of and risk factors for inguinal hernia. METHODS:We analyzed data from the Rotterdam Study, a prospective cohort study that observed the...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2014.09.029
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:Regional surgical quality improvement consortiums are becoming more common. Herein we have reported the effectiveness of a statewide consortium focusing on open vascular operative procedures. METHODS:The statewide Michigan Surgical Quality Consortium was established in 2005 with 16 hospitals that report cas...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2010.07.009
更新日期:2010-10-01 00:00:00
abstract:BACKGROUND:This study aimed to compare the radicality for and clinical advantages of laparoscopic liver resection, which is increasingly used, and the corresponding open procedure by propensity score matching analysis. METHODS:We analyzed 260 hepatocellular carcinoma patients who underwent initial liver resection at o...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2015.02.031
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:Publicly reported hospital scores are used by patients to make health care-related decisions; however, their relationship to clinical outcomes is unknown. METHODS:Through the use of the New York Statewide Planning and Research Cooperative System database, the association between two commonly used scores (He...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2018.12.006
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:Surgical residents have traditionally been evaluated by ward evaluations and multiple-choice testing; overall resident performance has seldom been objectively evaluated. We developed a comprehensive evaluation program for senior residents. The purpose of this study was to determine whether the several differ...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1994-10-01 00:00:00
abstract:BACKGROUND:Associating liver partition and portal vein ligation for staged hepatectomy induces an unprecedented liver hypertrophy and enables resection of otherwise unresectable liver tumors. The effect of associating liver partition and portal vein ligation for staged hepatectomy on tumor proliferation, however, remai...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2017.10.036
更新日期:2018-02-01 00:00:00