Abstract：
:Heterotopic rat heart allografts were performed in 35 rats. At intervals after transplantation, rats were killed and tissue concentrations of immunoassayable prostaglandin E (PGE) were measured in the native heart, transplanted heart, spleen, and thymus. A significant increase in allograft PGE activity was observed at days 5 through 7, coinciding with the onset of the rejection reaction. These studies implicate PGE in the host response to allografting, but further studies are needed to determine what (if any) role prostaglandins play in the rejection reaction.
journal_name
Surgeryjournal_title
Surgeryauthors
Jaffe BM,Moore TC,Vigran TSsubject
Has Abstractpub_date
1975-10-01 00:00:00pages
481-4issue
4eissn
0039-6060issn
1532-7361pii
0039-6060(75)90242-1journal_volume
78pub_type
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