当前位置： SCI文献检索 > SURGERY期刊下所有文献 > Parathyroidectomy for patients with secondary hyperparathyroidism in a changing landscape for the management of end-stage renal disease.

Parathyroidectomy for patients with secondary hyperparathyroidism in a changing landscape for the management of end-stage renal disease.

Abstract：

BACKGROUND:The landscape of patients with end-stage renal disease is changing with the increasing availability of kidney transplantation. In the near future, a less aggressive approach to treat secondary hyperparathyroidism might be beneficial. We report outcomes of parathyroidectomy for end-stage renal disease-related hyperparathyroidism comparing the outcomes of limited, subtotal, and total parathyroidectomy. METHODS:We performed a retrospective analysis of prospectively collected data. Patients were divided into 3 parathyroidectomy subgroups: limited (<3 glands removed), subtotal (3-3.5 glands), and total (4 glands) parathyroidectomy. Primary outcome was serum levels of parathyroid hormone. Secondary endpoints were serum levels of calcium, phosphate, and alkaline phosphatase, postoperative complications, and persistent or recurrent disease rates. RESULTS:In total, 195 patients were included for analysis of whom 13.8% underwent limited parathyroidectomy, 46.7% subtotal parathyroidectomy, and 39.5% total parathyroidectomy. Preoperative parathyroid hormone levels (pg/mL) were 471 (210-868), 1,087 (627-1,795), and 1,070 (475-1,632) for the limited, subtotal, and total parathyroidectomy groups, respectively (P < .001). A decrease in serum parathyroid hormone was seen in all groups; however, postoperative levels remained greater in the limited parathyroidectomy group compared to the subtotal and total parathyroidectomy groups (P < .001). Serum calcium, phosphate, and alkaline phosphatase levels decreased in all groups to within the reference range. In the limited parathyroidectomy group, persistent disease and recurrence occurred more frequently (P = .02 and P = .07, respectively). CONCLUSION:Subtotal parathyroidectomy is the optimal strategy in an era with an increasing availability of kidney transplantation and improved regimens of dialysis. In this changing practice, the approach to parathyroid surgery, however, might shift to a less aggressive and patient-tailored approach.

journal_name

Surgery

journal_title

Surgery

authors

van der Plas W,Kruijff S,Sidhu SB,Delbridge LW,Sywak MS,Engelsman AF

doi

10.1016/j.surg.2020.08.014

subject

Has Abstract

pub_date

2021-02-01 00:00:00

pages

275-281

issue

2

eissn

0039-6060

issn

1532-7361

pii

S0039-6060(20)30546-8

journal_volume

169

pub_type

杂志文章

相关文献

SURGERY文献大全
  • "Take the Volume Pledge" may result in disparity in access to care.

    abstract：BACKGROUND:"Take the Volume Pledge" proposes restricting pancreatectomies to hospitals that perform ≥20 per year. Our purpose was to identify those factors that characterize patients at risk for loss of access to pancreatic cancer care with enforcement of volume standards. METHODS:Using the Healthcare Cost and Utiliza...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：10.1016/j.surg.2016.07.017

    authors： Blanco BA,Kothari AN,Blackwell RH,Brownlee SA,Yau RM,Attisha JP,Ezure Y,Pappas S,Kuo PC,Abood GJ

    更新日期：2017-03-01 00:00:00

  • Circadian esophageal motor function in patients with gastroesophageal reflux disease.

    abstract：:Effective esophageal peristalsis is a major determinant of esophageal clearance function and may contribute to the development of complications in gastroesophageal reflux disease. Using 24-hour ambulatory esophageal manometry, we compared the circadian esophageal motor activity of normal volunteers to that of patients...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：

    authors： Stein HJ,Eypasch EP,DeMeester TR,Smyrk TC,Attwood SE

    更新日期：1990-10-01 00:00:00

  • Results of reoperation for hyperparathyroidism, with evaluation of preoperative localization studies.

    abstract：:During the past 3 years (June, 1974, to July, 1977), 51 patients underwent reoperation for persistent or recurrent hyperparathyroidism at the Mayo Clinica. The overall success rate for cervical reoperation was 72% and for mediastinal reoperation, was 64%. Arteriography alone provided accurate preoperative localization...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：

    authors： Edis AJ,Sheedy PF,Beahrs OH,van Heerden JA

    更新日期：1978-09-01 00:00:00

  • Laparoscopic staging for gastric cancer.

    abstract：BACKGROUND:Laparoscopy has become an increasingly important diagnostic tool for the staging of intraabdominal malignancies. Some investigators have suggested laparoscopy to be of questionable value in the preoperative staging of gastric cancer because many patients may require palliative surgery despite laparoscopic fi...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：10.1016/s0039-6060(96)80184-x

    authors： Lowy AM,Mansfield PF,Leach SD,Ajani J

    更新日期：1996-06-01 00:00:00

  • Progression and survival results after radical hepatic metastasectomy of indolent advanced neuroendocrine neoplasms (NENs) supports an aggressive surgical approach.

    abstract：BACKGROUND:Neuroendocrine neoplasms most commonly metastasize to the liver. Operative extirpation of neuroendocrine neoplasm hepatic metastases improves symptoms and seems to improve survival, but subsequent evidence is required. The current study evaluates the progression-free survival and overall survival of patients...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：10.1016/j.surg.2010.06.008

    authors： Saxena A,Chua TC,Sarkar A,Chu F,Liauw W,Zhao J,Morris DL

    更新日期：2011-02-01 00:00:00

  • Interactions of gastric blood flow, barrier breaker, and hydrogen ion back diffusion during ulcer formation in the rat.

    abstract：:A rat gastric chamber preparation was used to determine the interrelations between H+ back diffusion, mucosal blood flow, the area of mucosa treated with bile salts and ulcer formation. The rate of H+ back diffusion was found to be dependent on both mucosal blood flow and the area of mucosa exposed to bile salts. It i...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：

    authors： Mersereau WA,Hinchey EJ

    更新日期：1978-03-01 00:00:00

  • Matas, Antyllus, and endoaneurysmorrhaphy.

    abstract：:Much can be learned about the history of vascular surgery by tracing the treatment of aneurysms. Rudolph Matas played a major role in the development of the current therapy for these lesions. In the centennial of the signal case that set him on the road to surgical immortality, the details and setting of this operatio...

    journal_title：Surgery

    pub_type： 传,历史文章,杂志文章

    doi：

    authors： Friedman SG,Friedman MS

    更新日期：1989-06-01 00:00:00

  • Effect of surgical delay on survival outcomes in patients undergoing curative resection for primary hepatocellular carcinoma: Inverse probability of treatment weighting using propensity scores and propensity score adjustment.

    abstract：BACKGROUND:The evidence is conflicting regarding the effect of delays from the time of diagnosis to surgery on the survival in patients with hepatocellular carcinoma. We sought to investigate the impact of time to surgery on overall survival for patients who underwent curative resection for primary hepatocellular carci...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：10.1016/j.surg.2019.09.022

    authors： Kabir T,Syn N,Ramkumar M,Yeo EYJ,Teo JY,Koh YX,Lee SY,Cheow PC,Chow PKH,Chung AYF,Ooi LL,Chan CY,Goh BKP

    更新日期：2020-02-01 00:00:00

  • Nonsteroid, calcitonin-like factor from the adrenal gland.

    abstract：:The adrenal glands removed from mongrel adult dogs were used to evaluate calcitonin activity; calcitonin has been recognized since 1962 as being a potent hypocalcemic polypeptide. After removal of the glands the animals demonstrated a significant hypocalcemic period simulating a one-half maximal calcitonin effect, wh...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：

    authors： Kaplan EL,Peskin GW,Arnaud CD

    更新日期：1969-07-01 00:00:00

  • Personalized video feedback improves suturing skills of incoming general surgery trainees.

    abstract：BACKGROUND:The American Board of Surgery encourages graduating medical students to prepare for surgical residency before day 1. We sought to determine the impact of personalized video feedback on an advance preparation task. METHODS:We conducted a nonrandomized study comparing video feedback versus no feedback. We sen...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：10.1016/j.surg.2017.11.006

    authors： Naik ND,Abbott EF,Gas BL,Murphy BL,Farley DR,Cook DA

    更新日期：2018-04-01 00:00:00

  • Compartmentalized gastrosplenic and mesenteric venous hypertension after distal splenorenal shunt occlusion: response to mesocaval shunt and splenectomy.

    abstract：:This is a report of a patient with a thrombosed Warren shunt and recurrent variceal hemorrhage who demonstrated compartmentalized venous hypertension in the mesenteric and gastrosplenic systems. Although the mesenteric presssure was normalized by the construction of a mesocaval interposition shunt, the gastrosplenic v...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：

    authors： Law DK,Moore EE

    更新日期：1979-05-01 00:00:00

  • Estrogen receptor beta mediates acute myocardial protection following ischemia.

    abstract：BACKGROUND:Gender differences have been noted in acute ischemia/reperfusion injury. Estrogen and the estrogen receptors (ER) appear to play a critical role in cardiovascular gender differences, given that females have improved myocardial functional recovery associated with decreased tissue inflammation. It has been sug...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：10.1016/j.surg.2008.03.009

    authors： Wang M,Crisostomo PR,Markel T,Wang Y,Lillemoe KD,Meldrum DR

    更新日期：2008-08-01 00:00:00

  • Preoperative lymphocyte subsets and infectious complications after colorectal cancer surgery.

    abstract：:Peripheral lymphocytes, T cells, and T cell subsets of 141 consecutive patients with colorectal cancer were measured preoperatively to determine whether infectious complications could be predicted from derangements of T cell subsets. T cell subset abnormalities reportedly precede sepsis in patients with burn injuries....

    journal_title：Surgery

    pub_type： 杂志文章

    doi：

    authors： Tartter PI

    更新日期：1988-02-01 00:00:00

  • Myocardial opiate receptor activity is stereospecific, independent of muscarinic receptor antagonism, and may play a role in depressing cardiac function.

    abstract：:Earlier work has shown that morphine sulfate can produce a dose-related decrease in heart rate (HR) and cardiac output (CO) in isolated working rat hearts. This response is preventable with the use of the opiate receptor antagonist, naloxone hydrochloride. In this study, the stereospecificity of the opiate response wa...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：

    authors： Vargish T,Beamer KC,Daly T,Head R

    更新日期：1987-08-01 00:00:00

  • Effects of tumor removal and body weight loss on insulin resistance in patients with cancer.

    abstract：BACKGROUND:This study was conducted to evaluate the effects of tumor removal and body weight loss on insulin resistance. METHODS:Insulin sensitivity was examined in 12 patients with cancer and stable weight and five patients with cancer and weight loss before operation, six patients after complete tumor removal, and t...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：

    authors： Yoshikawa T,Noguchi Y,Matsumoto A

    更新日期：1994-07-01 00:00:00

  • Total gastrectomy in patients with gastric adenocarcinoma: Is there an advantage to the minimally invasive approach?

    abstract：BACKGROUND:Previous evaluations of the oncologic efficacy of minimally invasive approaches to total gastrectomy in gastric adenocarcinoma have been limited by sample size and duration of follow-up. METHODS:We queried the National Cancer Database to identify patients undergoing robotic and laparoscopic or open total ga...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：10.1016/j.surg.2019.05.041

    authors： Sweigert PJ,Eguia E,Nelson MH,Nassoiy SP,Knab LM,Abood G,Baker MS

    更新日期：2019-10-01 00:00:00

  • Patient-reported outcome measures: the importance of patient satisfaction in surgery.

    abstract：:In recent years, much attention has been paid to the assessment of the quality of health care. This focus has been driven mainly by a desire to improve health care and decrease inequalities within health care systems. As well as addressing key areas such as structure, process, and outcome, which are normally taken fro...

    journal_title：Surgery

    pub_type： 杂志文章,评审

    doi：10.1016/j.surg.2009.03.019

    authors： Chow A,Mayer EK,Darzi AW,Athanasiou T

    更新日期：2009-09-01 00:00:00

  • Expression of kinase genes in primary hyperparathyroidism: adenoma versus hyperplastic parathyroid tissue.

    abstract：BACKGROUND:Differentiation between parathyroid hyperplasia and adenoma is difficult and based on the surgeon's skill. Microarrays and other sophisticated research tools generate information about differential gene expression in various tissues. Exploration of genes that express differentially in 1 tissue will enable id...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：10.1067/msy.2002.128614

    authors： Schachter PP,Ayesh S,Schneider T,Laster M,Czerniak A,Hochberg A

    更新日期：2002-12-01 00:00:00

  • Recurrent laryngeal nerve palsy after thyroidectomy with routine identification of the recurrent laryngeal nerve.

    abstract：BACKGROUND:The aim of this study was to assess the risk of recurrent laryngeal nerve palsy (RLNP) after thyroidectomy with routine identification of the recurrent laryngeal nerve (RLN) during the operation. METHODS:The present study was confined to 521 patients, 348 total lobectomies and 178 total thyroidectomies, tre...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：10.1016/j.surg.2004.09.008

    authors： Chiang FY,Wang LF,Huang YF,Lee KW,Kuo WR

    更新日期：2005-03-01 00:00:00

  • Nonresponse to pre-operative chemotherapy does not preclude long-term survival after liver resection in patients with colorectal liver metastases.

    abstract：BACKGROUND:Liver resection is the only curative treatment offering a chance of long-term survival in patients with colorectal liver metastases (CRM). Recent data indicated that liver resection in patients with tumor progression while receiving chemotherapy was associated with poor outcome. The aim of the study was to i...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：10.1016/j.surg.2009.02.004

    authors： Neumann UP,Thelen A,Röcken C,Seehofer D,Bahra M,Riess H,Jonas S,Schmeding M,Pratschke J,Bova R,Neuhaus P

    更新日期：2009-07-01 00:00:00

  • Role of bactericidal permeability-increasing protein in the treatment of gram-negative pneumonia.

    abstract：BACKGROUND:Gram-negative infections are a major cause of morbidity and death. Bactericidal permeability-increasing protein (BPI) is an endotoxin-neutralizing protein that also exhibits potent bactericidal activity. This study compared the efficacy of a 23 kd recombinant N-terminal fragment of BPI (rBPI23) with that of ...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：

    authors： Kelly CJ,Cech AC,Argenteanu M,Gallagher H,Shou J,Minnard E,Daly JM

    更新日期：1993-08-01 00:00:00

  • Phenotype mapping of the multiple endocrine neoplasia type II syndrome.

    abstract：:The multiple endocrine neoplasia (MEN) IIb syndrome has been differentiated from MEN IIa by the presence of various phenotypic characteristics such as mucosal neuromas, marfanoid habitus, congenital skeletal anomalies, and prominent corneal nerves, as well as the lack of parathyroid involvement. Analysis of a kindred ...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：

    authors： Talpos GB,Jackson CE,Yott JB,Van Dyke DL

    更新日期：1983-10-01 00:00:00

  • Trainee satisfaction in surgery residency programs: modern management tools ensure trainee motivation and success.

    abstract：OBJECTIVE:To assess trainee satisfaction in their surgery residency with a validated instrument and identify the contributing factors. BACKGROUND:Currently, surgery is deemed unattractive by medical students and ignored by many candidates planning to enter an academic career. New insights on the rational for such lack...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：10.1016/j.surg.2011.07.037

    authors： von Websky MW,Oberkofler CE,Rufibach K,Raptis DA,Lehmann K,Hahnloser D,Clavien PA

    更新日期：2012-11-01 00:00:00

  • Active immunotherapy of pancreatic cancer with tumor cells genetically engineered to secrete multiple cytokines.

    abstract：BACKGROUND:Vaccination of tumor-bearing animals with tumor cells genetically engineered to secrete cytokines including interleukin-2 (IL-2) and interferon-gamma (IFN-gamma) has been shown to induce effective tumor-specific immune responses capable of inhibiting local and metastatic disease. Previous unsuccessful attemp...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：10.1016/s0039-6060(96)80285-6

    authors： Clary BM,Coveney EC,Blazer DG 3rd,Philip R,Lyerly HK

    更新日期：1996-08-01 00:00:00

  • Enhanced isolated pancreatic islet recovery and functionality in rats by 17beta-estradiol treatment of brain death donors.

    abstract：BACKGROUND:Current isolation techniques recover only 20% to 50% of the pancreatic islets. Brain death (BD) is characterized by activation of proinflammatory cytokines (PICs) with reduced islet yields and functionality. We previously reported that 17beta-estradiol (E2) induces cytoprotection to human islets exposed to P...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：10.1016/j.surg.2004.05.009

    authors： Eckhoff DE,Eckstein C,Smyth CA,Vilatoba M,Bilbao G,Rahemtulla FG,Young CJ,Anthony Thompson J,Chaudry IH,Contreras JL

    更新日期：2004-08-01 00:00:00

  • Sphincter of Oddi botulinum toxin injection to prevent pancreatic fistula after distal pancreatectomy.

    abstract：BACKGROUND:Postoperative pancreatic fistula represents the most important complication after distal pancreatectomy. The aim of this study was to evaluate the use of a preoperative endoscopic injection of botulinum toxin into the sphincter of Oddi to prevent postoperative pancreatic fistula (German Clinical Trials Regis...

    journal_title：Surgery

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.surg.2016.09.005

    authors： Hackert T,Klaiber U,Hinz U,Kehayova T,Probst P,Knebel P,Diener MK,Schneider L,Strobel O,Michalski CW,Ulrich A,Sauer P,Büchler MW

    更新日期：2017-05-01 00:00:00

  • Interstitial protease activation is the central event in progression to necrotizing pancreatitis.

    abstract：BACKGROUND:Although intracellular protease activation is thought to be an early event in acute pancreatitis, factors determining progression from edematous to necrotizing pancreatitis are largely unknown. With enterokinase as a probe and an immunoassay quantifying free trypsinogen activation peptides (TAP), we sought e...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：

    authors： Fernández-del Castillo C,Schmidt J,Warshaw AL,Rattner DW

    更新日期：1994-09-01 00:00:00

  • Neutrophil activation by expanded polytetrafluoroethylene is dependent on the induction of protein phosphorylation.

    abstract：BACKGROUND:Polymorphonuclear leukocyte (PMN) activation after interaction with implantable surfaces has been previously reported. The purpose of this study was to examine the mechanism of PMN activation in response to expanded polytetrafluoroethylene (ePTFE). METHODS:To demonstrate PMN activation, the cumulative produ...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：

    authors： Katz DA,Haimovich B,Greco RS

    更新日期：1994-08-01 00:00:00

  • Growth hormone attenuates the abnormal distribution of body water in critically ill surgical patients.

    abstract：BACKGROUND:Catabolic illness is associated with fluid retention and extracellular space expansion. To determine the effect of human growth hormone (GH) on body water compartments, critically ill surgical patients were studied for a 2-week period during which they either continued to receive standard intensive care unit...

    journal_title：Surgery

    pub_type： 临床试验,杂志文章

    doi：

    authors： Gatzen C,Scheltinga MR,Kimbrough TD,Jacobs DO,Wilmore DW

    更新日期：1992-08-01 00:00:00

  • Risk factors for inguinal hernia in middle-aged and elderly men: results from the Rotterdam Study.

    abstract：BACKGROUND:Prospective data on risk factors and the incidence of inguinal hernia are sparse, especially in an elderly population. The aim of this study was to determine the incidence of and risk factors for inguinal hernia. METHODS:We analyzed data from the Rotterdam Study, a prospective cohort study that observed the...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：10.1016/j.surg.2014.09.029

    authors： de Goede B,Timmermans L,van Kempen BJ,van Rooij FJ,Kazemier G,Lange JF,Hofman A,Jeekel J

    更新日期：2015-03-01 00:00:00