Clinical experience with 118 hepatic resections for hepatocellular carcinoma.

Abstract:

:During the recent 5 2/3 years, hepatic resection was performed on 118 patients with hepatocellular carcinoma. Ages ranged from 17 to 78 years with an average of 57 years. There were 101 males and 17 females. Underlying cirrhosis of the liver was found in 101 cases, and chronic hepatitis was found in 16 cases. Before surgery 62 patients had 71 associated conditions such as esophageal varices, diabetes mellitus, cholelithiasis, or peptic ulcer. Operations for the varices and cholelithiasis were performed simultaneously with hepatic resection in 15 and six patients, respectively. The operative mortality rate within 1 month was 7.6%, and the overall in-hospital death rate was 14.4%. In 94 patients with curative resection, the 2-year survival rate was 81.2% in patients without cirrhosis and 55.4% in patients with cirrhosis. The 4-year survival rate was 81.2% in the former and 34.8% in the latter group. The prognosis was significantly better in patients without cirrhosis than in those with cirrhosis. On the contrary, 21 of 24 patients with palliative resection died within 2 years despite extensive chemotherapy. The present results may indicate that the resectability rate of hepatocellular carcinoma is currently increasing, even in the presence of cirrhosis of the liver due to early detection of the tumor by current advances in diagnostic methods and also that major hepatic resection is possible in selected patients with cirrhosis.

journal_name

Surgery

journal_title

Surgery

authors

Nagasue N,Yukaya H,Ogawa Y,Sasaki Y,Chang YC,Niimi K

subject

Has Abstract

pub_date

1986-06-01 00:00:00

pages

694-701

issue

6

eissn

0039-6060

issn

1532-7361

pii

0039-6060(86)90294-1

journal_volume

99

pub_type

杂志文章

相关文献

SURGERY文献大全
  • Surgical reconstruction of the superior vena cava system: indications and results.

    abstract:BACKGROUND:Obstruction of the superior vena cava (SVC) secondary to malignant or benign diseases is rarely treated by surgical reconstruction. The purpose of this retrospective study is to report our experience and compare our results with previous data in the literature. METHODS:From 1993 to 2006, 24 patients underwe...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2008.08.003

    authors: Picquet J,Blin V,Dussaussoy C,Jousset Y,Papon X,Enon B

    更新日期:2009-01-01 00:00:00

  • Myocardial opiate receptor activity is stereospecific, independent of muscarinic receptor antagonism, and may play a role in depressing cardiac function.

    abstract::Earlier work has shown that morphine sulfate can produce a dose-related decrease in heart rate (HR) and cardiac output (CO) in isolated working rat hearts. This response is preventable with the use of the opiate receptor antagonist, naloxone hydrochloride. In this study, the stereospecificity of the opiate response wa...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Vargish T,Beamer KC,Daly T,Head R

    更新日期:1987-08-01 00:00:00

  • Bedside diagnostic minilaparoscopy in the intensive care patient.

    abstract:BACKGROUND:The diagnosis of acute abdominal conditions in the critically ill patient remains difficult. The goal of this study is to demonstrate the use of bedside minilaparoscopy as a diagnostic aid in the intensive care unit (ICU) in patients with possible intra-abdominal catastrophic condition. METHODS:Between Febr...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1067/msy.2002.122607

    authors: Gagné DJ,Malay MB,Hogle NJ,Fowler DL

    更新日期:2002-05-01 00:00:00

  • Downregulation of survivin by siRNA diminishes radioresistance of pancreatic cancer cells.

    abstract:BACKGROUND:Survivin is a member of the inhibitor of apoptosis protein family, which inhibits apoptosis and regulates cell division. Survivin is expressed by the majority of human cancers, including pancreatic adenocarcinoma. We have reported that its expression is correlated with shorter survival of pancreatic cancer p...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2005.05.009

    authors: Kami K,Doi R,Koizumi M,Toyoda E,Mori T,Ito D,Kawaguchi Y,Fujimoto K,Wada M,Miyatake S,Imamura M

    更新日期:2005-08-01 00:00:00

  • Cytoreductive hepatic surgery for neuroendocrine tumors.

    abstract::We retrospectively reviewed 37 patients who underwent hepatic resection between 1970 and 1989 to evaluate the role of cytoreductive hepatic surgery in patients with metastatic neuroendocrine tumors (carcinoid, 24; islet cell, 13). Seventeen resections were curative (no gross residual tumor); nine patients had symptoma...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: McEntee GP,Nagorney DM,Kvols LK,Moertel CG,Grant CS

    更新日期:1990-12-01 00:00:00

  • Cost-effectiveness analysis in surgery.

    abstract:BACKGROUND:With tighter constraints on health care spending, many recognize the need to identify and restrict clinical interventions that are not cost-effective. As a result, cost-effectiveness analysis is being used increasingly to assess the relative value of surgical interventions. METHODS AND RESULTS:We first pres...

    journal_title:Surgery

    pub_type: 杂志文章,评审

    doi:

    authors: Finlayson SR,Birkmeyer JD

    更新日期:1998-02-01 00:00:00

  • Hyperparathyroidism unmasked by the treatment of hypothyroidism secondary to Hashimoto's thyroiditis.

    abstract::Primary hyperparathyroidism masked by untreated hypothyroidism was first noted by Kissin and Bakst in 1947; since then there has been only a single case reported. As a result, it has been thought to be a rare complex of parathyroid disease. During the past 17 years we observed 17 patients who developed primary hyperpa...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Calandra DB,Shah K,Lawrence AM,Paloyan E

    更新日期:1984-12-01 00:00:00

  • Cutaneous malignant melanoma: current views on pathogenesis, diagnosis, and surgical management.

    abstract::Reliable cancer statistics reveal an unexplained increase in the incidence and rate of death from melanoma. Increased exposure to ultraviolet light does not seem to be a factor. Hormones may affect the incidence but do not influence survival. The recognition of the biologic evolution of different types of melanomas an...

    journal_title:Surgery

    pub_type: 杂志文章,评审

    doi:

    authors: Adam YG,Efron G

    更新日期:1983-04-01 00:00:00

  • A comparative study of postoperative complications after hepatectomy in patients with and without chronic liver disease.

    abstract:BACKGROUND:Although hepatic resection is the most reliable treatment for hepatocellular carcinoma, impaired liver function because of cirrhosis or chronic hepatitis contributes to relatively high rates of postoperative complications. We have reviewed a series of hepatectomies at our institution and investigated risk fa...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Midorikawa Y,Kubota K,Takayama T,Toyoda H,Ijichi M,Torzilli G,Mori M,Makuuchi M

    更新日期:1999-09-01 00:00:00

  • Effects of long-term lithium infusion on normal parathyroid tissue.

    abstract:BACKGROUND:Approximately 10% of patients taking lithium for manic-depressive disorders become hypercalcemic. It remains unclear whether lithium initiates disease or promotes underlying hyperparathyroidism. We have previously demonstrated that at therapeutic concentrations lithium stimulates in vitro incorporation of bo...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/s0039-6060(05)80258-2

    authors: Saxe A,Gibson G,Silveira E

    更新日期:1995-05-01 00:00:00

  • Validation of the prognostic value of lymph node ratio in patients with cutaneous melanoma: a population-based study of 8,177 cases.

    abstract:BACKGROUND:The proportion of positive among examined lymph nodes (lymph node ratio [LNR]) has been recently proposed as an useful and easy-to-calculate prognostic factor for patients with cutaneous melanoma. However, its independence from the standard prognostic system TNM has not been formally proven in a large series...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2011.02.021

    authors: Mocellin S,Pasquali S,Rossi CR,Nitti D

    更新日期:2011-07-01 00:00:00

  • Successful management of hepatic abscesses by percutaneous catheter drainage in chronic granulomatous disease.

    abstract::Chronic granulomatous disease (CGD) is a disorder of polymorphonuclear leukocytes that can cause multiple recurrent hepatic abscesses in 40% of those patients with the disorder. The mortality rate from this complication of CGD is estimated at 27%. Treatment has consisted of extensive surgical debridement and drainage ...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Skibber JM,Lotze MT,Garra B,Fauci A

    更新日期:1986-05-01 00:00:00

  • Regulation of coronary myoplasmic Ca(2+)-myosin light chain phosphorylation pathway and vasomotor tone: hyperpolarizing versus depolarizing cardioplegia.

    abstract:BACKGROUND:This study was designed to compare the effects of hyperpolarizing versus depolarizing cardioplegic solutions on the coronary vasomotor regulation, specifically focusing on coronary myoplasmic Ca2+-myosin light chain (MLC) phosphorylation pathway and beta-adrenergic signal transduction. METHODS:With the use ...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1067/msy.2000.107417

    authors: Matsuda N,Sellke FW

    更新日期:2000-08-01 00:00:00

  • Effects of bile acid and salicylate on isolated surface and glandular cells of rabbit stomach.

    abstract::Little is known about the response of surface cells and glandular cells of the gastric mucosa to various injurious agents. This study examines the effects of bile acid and salicylate on oxygen consumption and membraneolysis of isolated gastric mucosal surface cells and compares these responses to those of cells consti...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Tanaka K,Fromm D

    更新日期:1983-05-01 00:00:00

  • Aortocolic fistula caused by an ingested chicken bone.

    abstract::Primary aortocolic fistulas are a rare but lethal complication of aortic or iliac aneurysms. A case of fistula between a nonaneurysmal aortic bifurcation and sigmoid colon caused by an ingested chicken bone is presented. This cause of rectal bleeding, which has never been described, might have been suspected after car...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Caes F,Vierendeels T,Welch W,Willems G

    更新日期:1988-04-01 00:00:00

  • Normocalcemic hyperparathyroidism, kidney stones, and idiopathic hypercalciuria.

    abstract::Eighty-four patients with recurrent kidney stones, serum calcium levels in the upper normal quartile, and most of whom with hypercalciuria had their parathyroids surgically explored. Parathyroid adenomata were found in 19 patients, hyperplasia in 39, and normal parathyroids in 26. Postoperatively there was a significa...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Johansson H,Thorén L,Werner I,Grimelius L

    更新日期:1975-05-01 00:00:00

  • Clonidine reduces norepinephrine and improves bone marrow function in a rodent model of lung contusion, hemorrhagic shock, and chronic stress.

    abstract:BACKGROUND:Propranolol has been shown previously to restore bone marrow function and improve anemia after lung contusion/hemorrhagic shock. We hypothesized that daily clonidine administration would inhibit central sympathetic outflow and restore bone marrow function in our rodent model of lung contusion/hemorrhagic sho...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2016.08.043

    authors: Alamo IG,Kannan KB,Ramos H,Loftus TJ,Efron PA,Mohr AM

    更新日期:2017-03-01 00:00:00

  • Teratoma in the region of adrenal gland: a unique entity masquerading as lipomatous adrenal tumor.

    abstract:BACKGROUND:The aim of this study was to establish the clinical and pathologic aspects of 3 atypical lipomatous lesions in the region of the adrenal gland. METHODS:Three young Chinese patients (ages 18, 18, and 37 years) were seen for nonspecific back pain. Radiologic examination revealed a lipomatous lesion in the reg...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1067/msy.1999.98924

    authors: Lam KY,Lo CY

    更新日期:1999-07-01 00:00:00

  • Morbidity in patients with permanent hypoparathyroidism after total thyroidectomy.

    abstract:BACKGROUND:Permanent hypoparathyroidism is common after thyroidectomy. The present study evaluated the risk for morbidity in patients operated with total thyroidectomy with and without permanent hypoparathyroidism. METHODS:Data was retrieved from the Scandinavian Quality Register for Thyroid, Parathyroid, and Adrenal ...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2019.06.056

    authors: Bergenfelz A,Nordenström E,Almquist M

    更新日期:2020-01-01 00:00:00

  • Reversal of ischemic damage with amino acid substrate enhancement during reperfusion.

    abstract::Twenty dogs underwent 15 minutes of normothermic ischemic arrest and 30 minutes of reperfusion while on cardiopulmonary bypass. In 10 control dogs, the reperfusate blood was not modified. In 10 other dogs, the aorta was reclamped and the heart reperfused for 5 minutes with blood containing L-glutamate (0.026M). We mea...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Lazar HL,Buckberg GD,Manganaro AJ,Becker H,Maloney JV Jr

    更新日期:1980-11-01 00:00:00

  • Intraatrial extension of thyroid cancer: technique and results of a radical surgical approach.

    abstract::An occlusion of the superior vena cava by a tumor thrombus extending into the right atrium was diagnosed in three patients with a follicular thyroid cancer. All patients showed the typical clinical picture of the superior vena cava syndrome. A right parasternal thoracotomy was performed for preparation of the major ve...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Niederle B,Hausmaninger C,Kretschmer G,Polterauer P,Neuhold N,Mirza DF,Roka R

    更新日期:1990-12-01 00:00:00

  • Myeloid zinc finger-1 regulates expression of cancer-associated fibroblast and cancer stemness profiles in breast cancer.

    abstract:BACKGROUND:Osteopontin acts thru myeloid zinc finger-1 and transforming growth factor-β to drive the adoption of a cancer-associated fibroblast phenotype by local mesenchymal stem cells. Cancer-associated fibroblasts increase cancer cell stemness. METHODS:Mesenchymal stem cells were exposed to osteopontin or were cocu...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2019.05.042

    authors: Kuo MC,Kuo PC,Mi Z

    更新日期:2019-10-01 00:00:00

  • Living-unrelated renal transplantation provides comparable results to living-related renal transplantation: a 12-year single-center experience.

    abstract:BACKGROUND:The increasing success of renal transplantation is paralleled by the increased size of the waiting list. Efforts to increase the donor pool have included the use of living-unrelated kidney donors (LURDs). METHODS:During a 12-year period our center performed 309 transplantation from living donors; 279 patien...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/s0039-6060(96)80264-9

    authors: Lowell JA,Brennan DC,Shenoy S,Hagerty D,Miller S,Ceriotti C,Cole B,Howard TK

    更新日期:1996-05-01 00:00:00

  • Fluorometric quantification of low-dose fluorescein delivery to predict amputation site healing.

    abstract::This retrospective study evaluated quantification of skin fluorescein delivery by fiberoptic fluorometry as a means of predicting the healing potential of an amputation site. Fluorometry uses a dual-channel fiberoptic light guide--one channel transmits blue light to excite the fluorescein in the skin under study, and ...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Silverman DG,Roberts A,Reilly CA,Brousseau DA,Norton KJ,Bartley E,Neufeld GR

    更新日期:1987-03-01 00:00:00

  • Quality of post-treatment surveillance of early stage breast cancer in Texas.

    abstract:BACKGROUND:Only annual mammography and physical examination are recommended for the post-treatment surveillance of early stage breast cancer. METHODS:We used Texas Cancer Registry-Medicare linked data (2001-2007) to identify physician visits and use of mammography, magnetic resonance imaging (MRI), computed tomography...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2013.04.004

    authors: Parmar AD,Sheffield KM,Vargas GM,Han Y,Chao C,Riall TS

    更新日期:2013-08-01 00:00:00

  • Selective infusion of streptokinase for arterial thrombosis.

    abstract::We have treated 13 patients with limb-threatening ischemia caused by acute arterial thrombosis with selective arterial infusion of streptokinase. The indications for thrombolytic therapy included medical contraindication to surgery, surgically inaccessible thrombi, arterial thrombosis following percutaneous translumin...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Rush DS,Gewertz BL,Lu CT,Neely SM,Ball DG,Beasley M,Zarins CK

    更新日期:1983-06-01 00:00:00

  • Is there a role for sentinel node biopsy in early N0 tongue tumors?

    abstract:BACKGROUND:Detecting metastases to the cervical lymph nodes is the main problem in the management of squamous cell carcinoma of the tongue. We investigated the ability of sentinel node (SN) biopsy to predict neck status in 11 patients with lateral T1-T2, N0, and M0 squamous cell carcinoma of the tongue who underwent ip...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1067/msy.2000.106809

    authors: Chiesa F,Mauri S,Grana C,Tradati N,Calabrese L,Ansarin M,Mazzarol G,Paganelli G

    更新日期:2000-07-01 00:00:00

  • Interactions of gastric blood flow, barrier breaker, and hydrogen ion back diffusion during ulcer formation in the rat.

    abstract::A rat gastric chamber preparation was used to determine the interrelations between H+ back diffusion, mucosal blood flow, the area of mucosa treated with bile salts and ulcer formation. The rate of H+ back diffusion was found to be dependent on both mucosal blood flow and the area of mucosa exposed to bile salts. It i...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Mersereau WA,Hinchey EJ

    更新日期:1978-03-01 00:00:00

  • Chronic extrinsic denervation after small bowel transplantation in rat jejunum: Effects and adaptation in nitrergic and non-nitrergic neuromuscular inhibitory mechanisms.

    abstract:BACKGROUND:Extrinsic denervation of the transplanted small bowel could play a substantial role in motor dysfunction of the transplanted gut. We attempted to determine the effect of chronic extrinsic denervation on intestinal contractility. METHODS:Jejunal longitudinal muscle strips were obtained from rats 1 week and 8...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1067/msy.2001.112070

    authors: Balsiger BM,Ohtani N,Anding WJ,Duenes JA,Sarr MG

    更新日期:2001-04-01 00:00:00

  • Necrotizing enterocolitis totalis: High mortality in the absence of an aggressive surgical approach.

    abstract:BACKGROUND:Necrotizing enterocolitis is the leading case of gastrointestinal-related morbidity in premature infants. Necrotizing enterocolitis totalis is an aggressive form of necrotizing enterocolitis, which has traditionally been managed with comfort care. Recent advances in management of short bowel syndrome have re...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2019.03.005

    authors: Dukleska K,Devin CL,Martin AE,Miller JM,Sullivan KM,Levy C,Prestowitz S,Flathers K,Vinocur CD,Berman L

    更新日期:2019-06-01 00:00:00